Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Smap1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SMAP1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Smap1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SMAP1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | ISO | Smap1 (Mus musculus) | 6480464 | Estradiol results in decreased expression of SMAP1 mRNA | CTD | PMID:19484750 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of SMAP1 mRNA | CTD | PMID:29581250 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Smap1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SMAP1 mRNA | CTD | PMID:19465110 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SMAP1 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Smap1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SMAP1 mRNA | CTD | PMID:24680724 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of SMAP1 mRNA | CTD | PMID:30047161 | adefovir pivoxil | decreases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | adefovir dipivoxil results in decreased expression of SMAP1 mRNA | CTD | PMID:25596134 | aflatoxin B1 | decreases methylation | ISO | SMAP1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of SMAP1 gene | CTD | PMID:27153756 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of SMAP1 mRNA | CTD | PMID:30047161 | aristolochic acid A | decreases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SMAP1 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | increases methylation | ISO | SMAP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SMAP1 promoter | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | increases expression | ISO | Smap1 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of SMAP1 mRNA | CTD | PMID:19850644 | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Smap1 (Mus musculus) | 6480464 | PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of SMAP1 mRNA] | CTD | PMID:19850644 | bisphenol A | decreases expression | ISO | Smap1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of SMAP1 mRNA | CTD | PMID:26063408 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SMAP1 mRNA | CTD | PMID:25181051 | cadmium dichloride | decreases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of SMAP1 mRNA | CTD | PMID:25596134 | carbamazepine | affects expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of SMAP1 mRNA | CTD | PMID:25979313 | CGP 52608 | multiple interactions | ISO | SMAP1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SMAP1 gene] | CTD | PMID:28238834 | chloroacetaldehyde | affects expression | ISO | SMAP1 (Homo sapiens) | 6480464 | chloroacetaldehyde affects the expression of SMAP1 mRNA | CTD | PMID:25596134 | chlorpyrifos | decreases expression | ISO | Smap1 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of SMAP1 mRNA | CTD | PMID:32715474 | cidofovir anhydrous | decreases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Cidofovir results in decreased expression of SMAP1 mRNA | CTD | PMID:25596134 | cisplatin | multiple interactions | ISO | SMAP1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of SMAP1 mRNA | CTD | PMID:27392435 | clodronic acid | increases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Clodronic Acid results in increased expression of SMAP1 mRNA | CTD | PMID:25596134 | cobalt dichloride | increases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of SMAP1 mRNA | CTD | PMID:17553155 and PMID:19376846 | cyclosporin A | increases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of SMAP1 mRNA | CTD | PMID:20106945 more ... | dieldrin | increases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Dieldrin results in increased expression of SMAP1 mRNA | CTD | PMID:31068361 | dioxygen | increases expression | ISO | Smap1 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of SMAP1 mRNA | CTD | PMID:22629407 | dioxygen | increases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Oxygen deficiency results in increased expression of SMAP1 mRNA | CTD | PMID:25596134 | dioxygen | multiple interactions | ISO | Smap1 (Mus musculus) | 6480464 | Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of SMAP1 mRNA] | CTD | PMID:22629407 | doxorubicin | decreases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SMAP1 mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | SMAP1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SMAP1 protein | CTD | PMID:23301498 | ethanol | increases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Ethanol results in increased expression of SMAP1 protein | CTD | PMID:20621659 | ethanol | affects expression | ISO | Smap1 (Mus musculus) | 6480464 | Ethanol affects the expression of SMAP1 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | ISO | Smap1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SMAP1 mRNA | CTD | PMID:22206623 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SMAP1 mRNA | CTD | PMID:33387578 | isoprenaline | increases expression | ISO | Smap1 (Mus musculus) | 6480464 | Isoproterenol results in increased expression of SMAP1 mRNA | CTD | PMID:20003209 | ivermectin | decreases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SMAP1 protein | CTD | PMID:32959892 | methyl methanesulfonate | increases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of SMAP1 mRNA | CTD | PMID:23649840 | paracetamol | increases expression | ISO | Smap1 (Mus musculus) | 6480464 | Acetaminophen results in increased expression of SMAP1 mRNA | CTD | PMID:17585979 | pirinixic acid | increases expression | ISO | Smap1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of SMAP1 mRNA | CTD | PMID:18301758 | quercetin | decreases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of SMAP1 mRNA | CTD | PMID:21632981 | sodium arsenite | decreases methylation | ISO | Smap1 (Mus musculus) | 6480464 | sodium arsenite results in decreased methylation of SMAP1 gene | CTD | PMID:32068019 | sodium arsenite | decreases expression | ISO | Smap1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of SMAP1 mRNA | CTD | PMID:36209798 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of SMAP1 mRNA | CTD | PMID:30047161 | sunitinib | increases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of SMAP1 mRNA | CTD | PMID:31533062 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of SMAP1 mRNA | CTD | PMID:34492290 | tungsten | decreases expression | ISO | Smap1 (Mus musculus) | 6480464 | Tungsten results in decreased expression of SMAP1 mRNA | CTD | PMID:30912803 | tunicamycin | increases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of SMAP1 mRNA | CTD | PMID:22378314 | uranium atom | affects expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Uranium affects the expression of SMAP1 mRNA | CTD | PMID:15672453 | valproic acid | affects expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SMAP1 mRNA | CTD | PMID:25979313 | valproic acid | increases methylation | ISO | SMAP1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of SMAP1 gene | CTD | PMID:29501571 | valproic acid | decreases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SMAP1 mRNA and Valproic Acid results in decreased expression of SMAP1 protein | CTD | PMID:29501571 | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of SMAP1 gene | CTD | PMID:31682807 | vitamin E | increases expression | ISO | SMAP1 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of SMAP1 mRNA | CTD | PMID:19244175 | |