Gene: Tcf7l2 (transcription factor 7 like 2) Rattus norvegicus
Symbol: Tcf7l2
Name: transcription factor 7 like 2
Description: ENCODES a protein that exhibits armadillo repeat domain binding (ortholog); beta-catenin binding (ortholog); chromatin binding (ortholog); INVOLVED IN blood vessel development (ortholog); bone mineralization (ortholog); canonical Wnt signaling pathway (ortholog); PARTICIPATES IN altered Wnt signaling, canonical pathway; pancreatic cancer pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH Diabetes Mellitus, Type 2; Adenocarcinoma (ortholog); Arthritis, Juvenile (ortholog); FOUND IN beta-catenin-TCF7L2 complex (ortholog); catenin-TCF7L2 complex (ortholog); cytosol (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17beta-estradiol; bisphenol A
Type: protein-coding
Also known as: LOC679869; similar to transcription factor 7-like 2, T-cell specific, HMG-box; transcription factor 7-like 2; transcription factor 7-like 2 (T-cell specific, HMG-box); transcription factor 7-like 2, T-cell specific, HMG-box
Homo sapiens (human) : TCF7L2 (transcription factor 7 like 2)  HGNC  AGR
Mus musculus (house mouse) : Tcf7l2 (transcription factor 7 like 2, T cell specific, HMG box)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Tcf7l2 (transcription factor 7 like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TCF7L2 (transcription factor 7 like 2)
Canis lupus familiaris (dog) : TCF7L2 (transcription factor 7 like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tcf7l2 (transcription factor 7 like 2)
more info ...
Allele / Splice: Tcf7l2em1Mcwi  
Genetic Models: SS-Tcf7l2em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01276,686,911 - 276,730,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01283,387,566 - 283,412,364 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01284,077,353 - 284,118,928 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41262,031,823 - 262,226,710 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1250,490,882 - 250,683,257 (+)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Tcf7l2
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1583621
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2017-11-21
Status: ACTIVE