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Gene: Adam8 (ADAM metallopeptidase domain 8) Rattus norvegicus
Symbol: Adam8
Name: ADAM metallopeptidase domain 8
RGD ID: 1566394
Description: Predicted to have cell adhesion molecule binding activity; metal ion binding activity; and metallopeptidase activity. Predicted to be involved in several processes, including leukocyte migration; positive regulation of leukocyte migration; and positive regulation of macromolecule metabolic process. Predicted to colocalize with alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex. Orthologous to human ADAM8 (ADAM metallopeptidase domain 8); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: a disintegrin and metallopeptidase domain 8; disintegrin and metalloproteinase domain-containing protein 8; LOC499285; RGD1566394; similar to cysteine-rich glycoprotein
Homo sapiens (human) : ADAM8 (ADAM metallopeptidase domain 8)  HGNC  Alliance
Mus musculus (house mouse) : Adam8 (a disintegrin and metallopeptidase domain 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adam8 (ADAM metallopeptidase domain 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ADAM8 (ADAM metallopeptidase domain 8)
Canis lupus familiaris (dog) : ADAM8 (ADAM metallopeptidase domain 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adam8 (ADAM metallopeptidase domain 8)
Sus scrofa (pig) : ADAM8 (ADAM metallopeptidase domain 8)
Chlorocebus sabaeus (African green monkey) : ADAM8 (ADAM metallopeptidase domain 8)
Heterocephalus glaber (naked mole-rat) : Adam8 (ADAM metallopeptidase domain 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01212,317,510 - 212,332,895 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1212,317,848 - 212,330,349 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01219,236,436 - 219,251,059 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41199,780,772 - 199,791,855 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1192,454,105 - 192,468,808 (-)NCBICelera
Cytogenetic Map1q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Adam8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1566394
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.