Trmt2b (tRNA methyltransferase 2 homolog B) - Rat Genome Database

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Gene: Trmt2b (tRNA methyltransferase 2 homolog B) Rattus norvegicus
Analyze
Symbol: Trmt2b
Name: tRNA methyltransferase 2 homolog B
RGD ID: 1565132
Description: Predicted to enable rRNA (uridine-C5-)-methyltransferase activity and tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Orthologous to human TRMT2B (tRNA methyltransferase 2 homolog B); INTERACTS WITH (-)-epigallocatechin 3-gallate (ortholog); (1->4)-beta-D-glucan (ortholog); 1,2-dimethylhydrazine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC503462; RGD1565132; similar to RIKEN cDNA 4732479N06; tRNA (uracil(54)-C(5))-methyltransferase homolog; tRNA (uracil-5-)-methyltransferase homolog B
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X101,716,656 - 101,777,105 (-)NCBIGRCr8
mRatBN7.2X97,425,712 - 97,483,821 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.0X105,056,890 - 105,114,876 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X104,954,402 - 104,996,021 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X121,694,841 - 121,745,024 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX98,467,198 - 98,525,152 (-)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:18614015  


Genomics

Comparative Map Data
Trmt2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X101,716,656 - 101,777,105 (-)NCBIGRCr8
mRatBN7.2X97,425,712 - 97,483,821 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.0X105,056,890 - 105,114,876 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X104,954,402 - 104,996,021 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X121,694,841 - 121,745,024 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX98,467,198 - 98,525,152 (-)NCBICelera
Cytogenetic MapXq32NCBI
TRMT2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X100,973,366 - 101,052,111 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX101,009,346 - 101,052,116 (-)EnsemblGRCh38hg38GRCh38
GRCh37X100,264,339 - 100,307,100 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X100,151,187 - 100,193,726 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X100,070,692 - 100,113,215NCBI
CeleraX100,783,109 - 100,825,878 (-)NCBICelera
Cytogenetic MapXq22.1NCBI
HuRefX90,068,401 - 90,112,076 (-)NCBIHuRef
CHM1_1X100,157,442 - 100,200,214 (-)NCBICHM1_1
T2T-CHM13v2.0X99,416,819 - 99,495,549 (-)NCBIT2T-CHM13v2.0
Trmt2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X133,123,704 - 133,177,770 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX133,123,088 - 133,177,733 (-)EnsemblGRCm39 Ensembl
GRCm38X134,222,955 - 134,277,023 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX134,222,339 - 134,276,984 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X130,757,494 - 130,811,523 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X129,569,305 - 129,623,290 (-)NCBIMGSCv36mm8
CeleraX117,099,787 - 117,155,672 (-)NCBICelera
Cytogenetic MapXE3NCBI
cM MapX55.95NCBI
TRMT2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X100,607,508 - 100,650,697 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X100,611,112 - 100,654,304 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X90,210,740 - 90,253,863 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X100,347,795 - 100,389,981 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX100,347,795 - 100,389,981 (-)Ensemblpanpan1.1panPan2
TRMT2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X74,921,406 - 75,001,373 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X76,361,015 - 76,406,690 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X73,929,590 - 73,974,787 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X75,589,853 - 75,634,947 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X75,352,421 - 75,397,722 (-)NCBIUU_Cfam_GSD_1.0
Trmt2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X63,344,143 - 63,381,368 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493681394,441 - 129,010 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493681393,738 - 130,928 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRMT2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX82,690,392 - 82,735,521 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X82,638,456 - 82,741,659 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X90,777,612 - 90,810,528 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRMT2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X89,259,251 - 89,391,444 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX89,354,510 - 89,382,861 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606514,273,687 - 14,312,223 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Trmt2b
245 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_017602352   ⟹   XP_017457841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X101,716,656 - 101,777,105 (-)NCBI
mRatBN7.2X97,425,712 - 97,483,821 (-)NCBI
Rnor_6.0X105,056,890 - 105,114,876 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_017457841 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_017457841   ⟸   XM_017602352
- Sequence:


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565132 AgrOrtholog
BioCyc Gene G2FUF-1691 BioCyc
NCBI Gene 503462 ENTREZGENE
PhenoGen Trmt2b PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-01-03 Trmt2b  tRNA methyltransferase 2 homolog B  RGD1565132  similar to RIKEN cDNA 4732479N06  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1565132  similar to RIKEN cDNA 4732479N06   RGD1565132_predicted  similar to RIKEN cDNA 4732479N06 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565132_predicted  similar to RIKEN cDNA 4732479N06 (predicted)  LOC503462  similar to RIKEN cDNA 4732479N06  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC503462  similar to RIKEN cDNA 4732479N06      Symbol and Name status set to provisional 70820 PROVISIONAL