Srp72 (signal recognition particle 72)

Gene: Srp72 (signal recognition particle 72) Rattus norvegicus

Analyze

Symbol:

Srp72 (Ensembl: LOC108348180)

Name:

signal recognition particle 72 (Ensembl:signal recognition particle subunit SRP72-like)

RGD ID:

1564787

Description:

Predicted to enable 7S RNA binding activity; TPR domain binding activity; and signal recognition particle binding activity. Predicted to contribute to ribosome binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in endoplasmic reticulum. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Orthologous to human SRP72 (signal recognition particle 72); INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; buspirone.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC100910272; LOC108348046; LOC498351; signal recognition particle 72 kDa protein; signal recognition particle 72 kDa protein-like; signal recognition particle 72kDa; signal recognition particle subunit SRP72; signal recognition particle subunit SRP72-like; similar to signal recognition particle,72 kDa subunit

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SRP72 (signal recognition particle 72)	HGNC	Ensembl, HomoloGene, Inparanoid, OMA, OrthoDB, OrthoMCL, Treefam
Chinchilla lanigera (long-tailed chinchilla):	Srp72 (signal recognition particle 72)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SRP72 (signal recognition particle 72)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SRP72 (signal recognition particle 72)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Srp72 (signal recognition particle 72)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SRP72 (signal recognition particle 72)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SRP72 (signal recognition particle 72)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Srp72 (signal recognition particle 72)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SRP72 (signal recognition particle 72)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Srp72 (signal recognition particle 72)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	srp72 (signal recognition particle 72)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Srp72	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SRP72	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	srpa-72	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Related Pseudogenes:

Srp72-ps1

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	31,522,424 - 31,549,978 (-)	NCBI		GRCr8
mRatBN7.2	14	31,168,175 - 31,195,717 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	31,168,293 - 31,195,729 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	31,546,080 - 31,573,369 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	32,854,412 - 32,881,701 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	31,339,085 - 31,366,374 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	33,447,583 - 33,453,788 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	14	33,325,108 - 33,351,416 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	33,462,627 - 33,489,312 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	14	30,481,417 - 30,508,939 (-)	NCBI		Celera
Cytogenetic Map	14	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bone Marrow Failure Syndrome 1 (ISO)

Chemical and Drug Induced Liver Injury (ISO)

cholestasis (ISO)

Congenital Bone Marrow Failure Syndromes (ISO)

congenital disorder of glycosylation type IIk (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO)

5-fluorouracil (ISO)

acrolein (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

atazanavir sulfate (ISO)

azoxystrobin (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

buspirone (EXP)

caffeine (ISO)

carbon nanotube (ISO)

chenodeoxycholic acid (ISO)

chlorpyrifos (ISO)

coumarin (ISO)

cyclosporin A (ISO)

deguelin (ISO)

deoxycholic acid (ISO)

dexamethasone (ISO)

dibenzo[a,l]pyrene (ISO)

dibutyl phthalate (EXP)

dicrotophos (ISO)

disodium selenite (ISO)

ethanol (ISO)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

glafenine (EXP)

glycochenodeoxycholic acid (ISO)

glycocholic acid (ISO)

glycodeoxycholic acid (ISO)

glyphosate (ISO)

hydralazine (ISO)

hydrogen peroxide (ISO)

indometacin (ISO)

inulin (ISO)

ivermectin (ISO)

methapyrilene (EXP)

methyl methanesulfonate (ISO)

nefazodone (ISO)

nickel sulfate (ISO)

oxaliplatin (ISO)

ozone (ISO)

p-menthan-3-ol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

picoxystrobin (ISO)

resveratrol (ISO)

rimonabant (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

triptonide (ISO)

trovafloxacin (EXP)

tungsten (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

SRP-dependent cotranslational protein targeting to membrane (IBA)

Cellular Component

endoplasmic reticulum (ISO)

signal recognition particle (ISO)

signal recognition particle, endoplasmic reticulum targeting (IBA,ISO)

Molecular Function

7S RNA binding (IBA,ISO)

protein binding (ISO)

ribosome binding (IBA,ISO)

signal recognition particle binding (ISO)

TPR domain binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15632090	PMID:17254600	PMID:18089836	PMID:22541560	PMID:22658674	PMID:22681889	PMID:27899666

Genomics

Comparative Map Data

Srp72
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	31,522,424 - 31,549,978 (-)	NCBI		GRCr8
mRatBN7.2	14	31,168,175 - 31,195,717 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	31,168,293 - 31,195,729 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	31,546,080 - 31,573,369 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	32,854,412 - 32,881,701 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	31,339,085 - 31,366,374 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	33,447,583 - 33,453,788 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	14	33,325,108 - 33,351,416 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	33,462,627 - 33,489,312 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	14	30,481,417 - 30,508,939 (-)	NCBI		Celera
Cytogenetic Map	14	p11	NCBI

SRP72
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	56,467,617 - 56,503,681 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	56,467,617 - 56,503,681 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	57,333,783 - 57,369,847 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	57,028,519 - 57,064,604 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	57,174,717 - 57,210,775	NCBI
Celera	4	54,840,136 - 54,876,261 (+)	NCBI		Celera
Cytogenetic Map	4	q12	NCBI
HuRef	4	53,287,903 - 53,323,943 (+)	NCBI		HuRef
CHM1_1	4	57,368,898 - 57,404,983 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	59,955,623 - 59,991,687 (+)	NCBI		T2T-CHM13v2.0

Srp72
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955447	14,519,064 - 14,552,758 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955447	14,519,978 - 14,552,758 (-)	NCBI	ChiLan1.0	ChiLan1.0

SRP72
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	73,276,204 - 73,312,588 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	73,481,727 - 73,518,107 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	67,420,551 - 67,456,065 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	73,989,304 - 74,025,906 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	73,989,304 - 74,025,906 (-)	Ensembl	panpan1.1		panPan2

SRP72
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	48,688,295 - 48,717,826 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	48,688,295 - 48,717,824 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	48,578,763 - 48,608,289 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	49,302,508 - 49,332,068 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	49,302,504 - 49,332,069 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	48,974,564 - 49,004,098 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	48,503,375 - 48,532,917 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	49,449,469 - 49,479,000 (+)	NCBI		UU_Cfam_GSD_1.0

Srp72
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	27,576,494 - 27,611,170 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936482	18,687,046 - 18,721,757 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936482	18,687,088 - 18,721,734 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SRP72
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	55,729,116 - 55,762,015 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	55,729,202 - 55,762,298 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	57,788,069 - 57,820,984 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SRP72
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	12,127,817 - 12,162,992 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	12,126,607 - 12,162,951 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666066	12,801,516 - 12,838,175 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Srp72
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624761	12,917,855 - 12,949,457 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624761	12,917,855 - 12,949,423 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Srp72
183 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	483
Count of miRNA genes:	215
Interacting mature miRNAs:	247
Transcripts:	ENSRNOT00000002862, ENSRNOT00000066382
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
619619	Rf4	Renal disease susceptibility QTL 4	4.1	0.002	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	14	1	32754612	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41131407	Rat
1581500	Renag1	Renal agenesis QTL 1			kidney development trait (VT:0000527)	percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)	14	8170668	68298175	Rat
1358296	Ael3	Aortic elastin QTL 3	3.7	0.00051	aorta elastin amount (VT:0003905)	aortic elastin	14	8267090	53267090	Rat
2302045	Pia39	Pristane induced arthritis QTL 39	4.9	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G2a level (CMO:0002116)	14	8267090	53267090	Rat
731183	Pia20	Pristane induced arthritis QTL 20	3.55		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	9088978	39057237	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11030622	95876975	Rat
71117	Niddm17	Non-insulin dependent diabetes mellitus QTL 17	2.35		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	17593761	42336881	Rat
631262	Tcas4	Tongue tumor susceptibility QTL 4	7.29		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	14	17622561	42337007	Rat
2313397	Coatc1	Coat color QTL1			coat/hair pigmentation trait (VT:0010463)	coat/hair color measurement (CMO:0001808)	14	18541332	63541332	Rat
61420	Pia6	Pristane induced arthritis QTL 6	4.9		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	14	18631345	42337007	Rat
10755459	Coatc15	Coat color QTL 15		0.01681	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	14	19836944	64836944	Rat
70187	Pancm5	Pancreatic morphology QTL 5	16.7		pancreas mass (VT:0010144)	pancreas weight to body weight ratio (CMO:0000630)	14	30320092	80829842	Rat
2324617	Coatc2	Coat color QTL 2		0.001	coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	14	30767025	39153750	Rat
1300154	Bp189	Blood pressure QTL 189	3.04		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	14	30883777	68757901	Rat

Markers in Region

RH128274

Rat Assembly	Chr	Position (strand)	Source
Celera	14	30,482,075 - 30,482,269	UniSTS
RH 3.4 Map	14	382.58	UniSTS
Cytogenetic Map	14	p11	UniSTS

BF393957

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	31,197,040 - 31,197,170 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	33,966,121 - 33,966,250	NCBI	Rnor6.0
Rnor_6.0	14	33,561,839 - 33,561,968	NCBI	Rnor6.0
Rnor_5.0	14	33,750,638 - 33,750,767	UniSTS	Rnor5.0
Rnor_5.0	14	33,352,752 - 33,352,881	UniSTS	Rnor5.0
RGSC_v3.4	14	33,490,662 - 33,490,791	UniSTS	RGSC3.4
Celera	14	30,510,275 - 30,510,404	UniSTS
RH 3.4 Map	14	426.69	UniSTS
Cytogenetic Map	14	p11	UniSTS
Cytogenetic Map	1	q21	UniSTS

RH139020

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	75,386,095 - 75,386,271 (+)	MAPPER	mRatBN7.2
mRatBN7.2	1	75,982,835 - 75,983,011 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	33,452,112 - 33,452,287	NCBI	Rnor6.0
Rnor_6.0	1	76,651,499 - 76,651,674	NCBI	Rnor6.0
Rnor_5.0	1	77,941,115 - 77,941,290	UniSTS	Rnor5.0
Rnor_5.0	14	33,242,190 - 33,242,365	UniSTS	Rnor5.0
RGSC_v3.4	1	75,191,614 - 75,191,790	UniSTS	RGSC3.4
RGSC_v3.4	1	75,122,862 - 75,123,037	UniSTS	RGSC3.4
RH 3.4 Map	18	393.5	UniSTS
Cytogenetic Map	1	q21	UniSTS
Cytogenetic Map	14	p11	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001170601	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092285	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC088335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC107914	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC158784	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000002862 ⟹ ENSRNOP00000002862

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	31,168,293 - 31,195,729 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000066382 ⟹ ENSRNOP00000061978

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	31,168,293 - 31,195,729 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000104763 ⟹ ENSRNOP00000082438

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	31,168,293 - 31,195,729 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000108068 ⟹ ENSRNOP00000097343

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	31,168,293 - 31,195,729 (-)	Ensembl

RefSeq Acc Id:

NM_001170601 ⟹ NP_001164072

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	31,522,445 - 31,549,974 (-)	NCBI
mRatBN7.2	14	31,168,175 - 31,195,705 (-)	NCBI
Rnor_6.0	14	33,447,583 - 33,453,788 (-)	NCBI
Rnor_5.0	14	33,325,108 - 33,351,416 (-)	NCBI
Celera	14	30,481,417 - 30,508,939 (-)	NCBI

Sequence:

show sequence

CCCCACCTCCACCTTCTCCAAGATGGCGAGCGGCGGCAGCGGTGGGGTGTCAGTCCCTGCGCTG
TGGAGTGAGGTGAACCGTTATGGGCAGAACAGCGACTTCACGCGTGCCCTCAAGACCGTCAACA
AAATATTGCAGATCAACAAGGATGATGTCACGGCCTTGCACTGTAAAGTTGTTTGCCTTATCCA
GAATGGAAGTTTCAAAGAAGCCTTGAATGTCATCAATACTCACACCAAAGTGTTAGCCAATAAC
TCTCTGTCCTTTGAGAAGGCATATTGCGAGTACAGGTTGAACAGAATCGAGAATGCCTTGAAGA
CAATAGAAAGTGCCAACCAGCAGACAGACAAACTGAAGGAGCTTTATGGACAAGTGCTGTACCG
CCTGGAACGCTACGATGAGTGCCTGGCCGTGTACCGAGATCTTGTCCGAAACTCCCAGGATGAC
TACGATGAGGAGAGGAAGACAAACCTGTCAGCAGTCGTTGCCGCTCAAAGCAACTGGGAAAAAG
TGGTTCCCGAGAACTTGGGTCTCCAAGAAGGCACACACGAACTCTGTTACAACGCTGCGTGTGC
ACTGATAGGGCAAGGCCAGCTGACCCAGGCAATGAAAATCCTACAAAAGGCTGAAGATCTTTGT
CGCCGTTCATTTTCAGAAGATTCAGACGGGACTGAGGAAGACCCTCAGGCCGAGCTGGCCATCA
TTCACGGTCAAATGGCTTACATCATGCAGCTTCAGGGGCGCATCGAGGAGGCTCTGCAGCTTTA
CAATCAGATAATAAAACTGAAGCCAACAGATGTGGCACTTCTTGCTGTAATCGCAAATAACATC
ATCACCATTAATAAGGACCAAAATGTCTTTGACTCCAAGAAGAAAGTGAAATTAACCAATGCAG
AAGGAGTAGAGTTTAAGCTCTCCAAGAGACAGCTTCAAGCCATAGAGTTCAACAAGGCTTTGCT
TGCCATGTATACAAACCAGGCAGAACAGTGCCGAAAAATAGCTTCTAGCTTGCAGTCCCAGAGT
CCTGAGCATCTCCTGCCTGTGCTGATCCAAGCTGCCCAGCTCTGTCGTGAAAAGCAGCATACAA
AGGCAATAGAGCTGCTTCAGGAATTTTCTGATCAACATCCAGAAAATGCAGCTGAAATCAAGCT
TACCATGGCTCAATTGAAAATTTCCCAAGGTAATATTTCCAAAGCGTGCCTAATACTGAGAAGC
ATAGAGGAGTTAAAGCATAAGCCAGGCATGGTATCCGCGTTGGTGACCATGTACAGCCATGAGG
AAGACATTGATAGTGCCATTGAAGTCTTCACACAGGCTATCCAGTGGTATCAAAGCCATCAGCC
CAAGTCCCCTGCTCATTTGTCCTTGATAAGAGAGGCCGCAAACTTCAAGCTCAAATATGGACGG
AAGAAGGAGGCAGTTAGTGACCTAGAGCAGCTGTGGAAACAAAATTCAAAAGATATTCACACGC
TAGCCCAGCTTATCTCTGCTTACTCACTTGTGGATCCAGAGAAAGCAAAGGCTCTTAGTAAACA
CCTGCCCTCATCGGATAGTATGTCTCTAAAGGTAGATGTTGAGGCTCTTGAGAATTCTCCTGGT
GCTACGTACATTCGGAAGAAGGGTGGAAAAGTTACTGGAGATAATCAACCAAAGGAACAAGGAC
AGGGAGATTTGAAGAAGAAGAAGAAGAAAAAGAAAGGAAAACTGCCTAAGAATTATGACCCAAA
AGTTACCCCAGATCCAGAAAGATGGCTACCAATGCGAGAGCGCTCTTACTACCGAGGAAGAAAG
AAGGGCAAAAAGAAGGACCAGATCGGAAAAGGAACACAGGGAGCGACCGCAGGAGCCTCCTCTG
AGCTGGACGCCAGTAAAACTGTGAGCAGCCCACCCACCTCCCCAAGACCTGGCAGTGCGGCAAC
GATGGCCTCCTCTACAAGTAACATTGTACCCCCAAGACACCAGAAACCCGCAGGGGCCCCAGCA
ACGAAAAAGAAGCAGCAACAGAAGAAGAAGAAAGGAGGGAAAAGTGGTTGGTGATGGCAGTACA
CTTGTCACAGGCTGTTCTTAACCCAGTGTCAGCGACATTAGGGACATAATAAAGGTGACACAGC
AAGAAGCACAGAGCTCCCTCCTCCATCCCCATAGTCCTGAAATGATTTCTTACACTTGAGATGG
GAAAGCAGCACCCTCCTCAGACTGCCTAGTCAAACTCGGCCTGTGTACCAAATAGCTTTCCAGG
GAGAGGCCTGCAGATGGCAGCACAAGACAAAGACAGGCTTTCCAGGGCTCCCGGGGTTTAAATT
CTCTAGTGGGAAAATACATGCTCCTATCAAGTCGCACCTTAAATTATGTCTTACAAGGCTAAAC
CTGGAATCTTCTGAGCATTCCAAGTATGTGTTTAGAGCTATCATGGATGAAAAAGGATCTGAGG
AACCAAGTGGCCAGACTCACCGTCTAAAATAATCTTAACCATAAATTCTGTCCTGTGATACTGG
AACGGGGACACTTTCACATGTGTGTGTATATTTGTGCACATCTGACTCCTTTGTACCTTTGTCG
TTTTCATTTTCGGATTATGTTAACATGCTGATTTAGTTCCACTGAAGACCTCAGAAACTGTATC
AGTGTTCCAAGTAGTTGACTCTTAGACCCAGGGTTCCGAGGGCAAATGGGTTCGGGCTTCTCAA
TCAGAACACTTAATGGCTACTATCAAGAACATAAAAGTCGGCTTCTTTATCGTAAGAGGAAACA
ATGTCAGGCGGTATTGACATTCACAGGAGCATTTGGCCCTGTTAATAATCAGATGGCTCCCCTT
TCTGGTTATGGGACATGACCATCATTACCTTTTTCAAAGTGCCGTGGTCTGCAGTCATTCTGTG
GCCTGAATGCTGCTCCCGTCTTTCATTGCTAGCAGGCCACTGTCACACTCAGCAGTCGTGAGAC
ACACACGGGTGCCTCCCCATGCTTAGGACTCATTTATGCCACCTGAGGTATCATTCGTTTCACA
CCTATATTTCCTGTGGTCAGTTACTCTGTTCTTGTTAATAAACGTGCTGCTGTGCGGAGCATTA
TCTATTGAAACGTCTTCAGTGGGTTTTTGTAAGGCTCTCCTGCTCCATGGAATTAGAAATGGGG
GTTGCTTTTCTGTTTGCCATAGTCAGTATGTGCAGTGGCGTCTAAGGAGGATTACACTGCTCTC
CAGAGGACTGAGTACCTGCTACAGGACTAGTGTTTAGGATTGCACCTCCTTTGCTTAAGCGGAC
CGACAGAATCTTGGTGTACTAAACCTTGAGAATTTTGTTCTAAGACATCATGGCGAAATACATA
CATAGTCCTCTTAGTTAGCATTGCTAGCATTTAATACTGTCATTGCTAAGCCACAGAAACCTCA
TTTCAAATAAGTTATTTATCTAAACTTCATCTGTATTAACACTCTAGTAGCTATTTGGGGAGAA
GTCTTTAACCAGTTCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT
GTGTGCGCGCGTTAATAAAAAACTATGTGGAGAACCTCATTCTCTGTGTCACATTTTAAAATAA
ATATTAAAATAAA

hide sequence

RefSeq Acc Id:

XM_039092285 ⟹ XP_038948213

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	31,522,424 - 31,549,978 (-)	NCBI
mRatBN7.2	14	31,168,508 - 31,195,717 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001164072	(Get FASTA)	NCBI Sequence Viewer
	XP_038948213	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI07915	(Get FASTA)	NCBI Sequence Viewer
	AAI58785	(Get FASTA)	NCBI Sequence Viewer
	EDL89886	(Get FASTA)	NCBI Sequence Viewer
	EDL89887	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000002862
	ENSRNOP00000002862.5
	ENSRNOP00000061978.2
	ENSRNOP00000082438.1
	ENSRNOP00000097343
	ENSRNOP00000097343.1

RefSeq Acc Id:

NP_001164072 ⟸ NM_001170601

- UniProtKB:

A0A8I6AW91 (UniProtKB/TrEMBL), F7FFH0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASGGSGGVSVPALWSEVNRYGQNSDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEA
LNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDEC
LAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNAACALIGQGQL
TQAMKILQKAEDLCRRSFSEDSDGTEEDPQAELAIIHGQMAYIMQLQGRIEEALQLYNQIIKLK
PTDVALLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKRQLQAIEFNKALLAMYTNQA
EQCRKIASSLQSQSPEHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKI
SQGNISKACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQSHQPKSPAHLS
LIREAANFKLKYGRKKEAVSDLEQLWKQNSKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSM
SLKVDVEALENSPGATYIRKKGGKVTGDNQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPER
WLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATMASSTSN
IVPPRHQKPAGAPATKKKQQQKKKKGGKSGW

hide sequence

RefSeq Acc Id:	XP_038948213 ⟸ XM_039092285
- Peptide Label:	isoform X1
- UniProtKB:	D4A7R0 (UniProtKB/TrEMBL), F7FFH0 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000097343 ⟸ ENSRNOT00000108068

RefSeq Acc Id:

ENSRNOP00000082438 ⟸ ENSRNOT00000104763

RefSeq Acc Id:

ENSRNOP00000061978 ⟸ ENSRNOT00000066382

RefSeq Acc Id:

ENSRNOP00000002862 ⟸ ENSRNOT00000002862

Protein Domains

Signal recognition particle SRP72 subunit RNA-

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A7R0-F1-model_v2	AlphaFold	D4A7R0	1-670	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1564787	AgrOrtholog
BioCyc Gene	G2FUF-15967	BioCyc
Ensembl Genes	ENSRNOG00000002100	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000002862.7	UniProtKB/TrEMBL
	ENSRNOT00000066382.2	UniProtKB/TrEMBL
	ENSRNOT00000104763.1	UniProtKB/TrEMBL
	ENSRNOT00000108068	ENTREZGENE
	ENSRNOT00000108068.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7302022	IMAGE-MGC_LOAD
	IMAGE:7460077	IMAGE-MGC_LOAD
InterPro	Signal_recog_part_SRP72_RNA-bd	UniProtKB/TrEMBL
	SRP72	UniProtKB/TrEMBL
	SRP_TPR-like	UniProtKB/TrEMBL
	TPR-like_helical_dom_sf	UniProtKB/TrEMBL
	TPR_repeat	UniProtKB/TrEMBL
KEGG Report	rno:498351	UniProtKB/TrEMBL
MGC_CLONE	MGC:125258	IMAGE-MGC_LOAD
	MGC:188145	IMAGE-MGC_LOAD
NCBI Gene	498351	ENTREZGENE
PANTHER	PTHR14094	UniProtKB/TrEMBL
	SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72	UniProtKB/TrEMBL
Pfam	SRP72	UniProtKB/TrEMBL
	SRP_TPR_like	UniProtKB/TrEMBL
	TPR_8	UniProtKB/TrEMBL
PhenoGen	Srp72	PhenoGen
PIRSF	SRP72	UniProtKB/TrEMBL
PROSITE	TPR	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000002100	RatGTEx
SMART	TPR	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48452	UniProtKB/TrEMBL
UniProt	A0A8I5ZUX3_RAT	UniProtKB/TrEMBL
	A0A8I6AW91	ENTREZGENE, UniProtKB/TrEMBL
	B0BND9_RAT	UniProtKB/TrEMBL
	D4A7R0	ENTREZGENE, UniProtKB/TrEMBL
	F7FFH0	ENTREZGENE, UniProtKB/TrEMBL
	Q32PZ7_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Srp72	signal recognition particle 72	LOC108348046	signal recognition particle subunit SRP72-like	Data merged from RGD:11446996	737654	PROVISIONAL
2016-08-02	LOC108348046	signal recognition particle subunit SRP72-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2015-02-26	Srp72	signal recognition particle 72	LOC100910272	signal recognition particle 72 kDa protein-like	Data merged from RGD:6499144	737654	APPROVED
2012-07-05	LOC100910272	signal recognition particle 72 kDa protein-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2011-06-09	Srp72	signal recognition particle 72kDa	Srp72	signal recognition particle 72	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-06-09	Srp72	signal recognition particle 72	Srp72	signal recognition particle 72kDa	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-05	Srp72	signal recognition particle 72	LOC498351	similar to signal recognition particle,72 kDa subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	LOC498351	similar to signal recognition particle,72 kDa subunit			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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