Krtap14 (keratin associated protein 14) - Rat Genome Database

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Gene: Krtap14 (keratin associated protein 14) Rattus norvegicus
Analyze
Symbol: Krtap14
Name: keratin associated protein 14
RGD ID: 1564302
Description: Predicted to be located in cytosol and keratin filament. Orthologous to human KRTAP23-1 (keratin associated protein 23-1); INTERACTS WITH bisphenol A; indole-3-methanol; 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: keratin-associated protein 14; LOC501768; RGD1564302; similar to anagen-specific protein mKAP13
RGD Orthologs
Human
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81141,612,876 - 41,613,718 (-)NCBIGRCr8
mRatBN7.21128,126,660 - 28,127,502 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1128,126,660 - 28,127,502 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1136,812,711 - 36,813,553 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01129,512,783 - 29,513,625 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01128,692,487 - 28,693,329 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01128,776,761 - 28,777,603 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1128,776,761 - 28,777,603 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01132,395,932 - 32,396,774 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41128,648,990 - 28,649,832 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1127,842,106 - 27,842,948 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Krtap14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81141,612,876 - 41,613,718 (-)NCBIGRCr8
mRatBN7.21128,126,660 - 28,127,502 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1128,126,660 - 28,127,502 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1136,812,711 - 36,813,553 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01129,512,783 - 29,513,625 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01128,692,487 - 28,693,329 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01128,776,761 - 28,777,603 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1128,776,761 - 28,777,603 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01132,395,932 - 32,396,774 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41128,648,990 - 28,649,832 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1127,842,106 - 27,842,948 (-)NCBICelera
Cytogenetic Map11q11NCBI
KRTAP23-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382130,348,399 - 30,348,606 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2130,348,399 - 30,348,606 (-)EnsemblGRCh38hg38GRCh38
GRCh372131,720,717 - 31,720,924 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362130,642,588 - 30,642,795 (-)NCBINCBI36Build 36hg18NCBI36
Build 342130,642,587 - 30,642,795NCBI
Celera2116,903,853 - 16,904,060 (-)NCBICelera
Cytogenetic Map21q22.11NCBI
HuRef2117,129,599 - 17,129,806 (-)NCBIHuRef
CHM1_12131,282,425 - 31,282,632 (-)NCBICHM1_1
T2T-CHM13v2.02128,714,272 - 28,714,479 (-)NCBIT2T-CHM13v2.0
Krtap14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391688,622,179 - 88,623,033 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1688,622,178 - 88,623,033 (-)EnsemblGRCm39 Ensembl
GRCm381688,825,291 - 88,826,145 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1688,818,667 - 88,826,145 (-)EnsemblGRCm38mm10GRCm38
MGSCv371688,825,536 - 88,826,390 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361688,714,149 - 88,714,991 (-)NCBIMGSCv36mm8
Celera1689,028,533 - 89,029,387 (-)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1651.41NCBI

Variants

.
Variants in Krtap14
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:41
Count of miRNA genes:38
Interacting mature miRNAs:41
Transcripts:ENSRNOT00000002132
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

integumental system musculoskeletal system appendage
High
Medium
Low 2 2 2
Below cutoff 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000002132   ⟹   ENSRNOP00000065994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1128,126,660 - 28,127,502 (-)Ensembl
Rnor_6.0 Ensembl1128,776,761 - 28,777,603 (-)Ensembl
RefSeq Acc Id: NM_001109326   ⟹   NP_001102796
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81141,612,876 - 41,613,718 (-)NCBI
mRatBN7.21128,126,660 - 28,127,502 (-)NCBI
Rnor_6.01128,776,761 - 28,777,603 (-)NCBI
Rnor_5.01132,395,932 - 32,396,774 (-)NCBI
RGSC_v3.41128,648,990 - 28,649,832 (-)RGD
Celera1127,842,106 - 27,842,948 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001102796 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM10667 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000065994
  ENSRNOP00000065994.2
Reference Protein Sequences
RefSeq Acc Id: NP_001102796   ⟸   NM_001109326
- UniProtKB: M0R933 (UniProtKB/TrEMBL),   A6JLA2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000065994   ⟸   ENSRNOT00000002132

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R933-F1-model_v2 AlphaFold M0R933 1-168 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698033
Promoter ID:EPDNEW_R8557
Type:single initiation site
Name:Krtap14_1
Description:keratin associated protein 14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01128,777,599 - 28,777,659EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564302 AgrOrtholog
BioCyc Gene G2FUF-22011 BioCyc
Ensembl Genes ENSRNOG00000001567 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002132 ENTREZGENE
  ENSRNOT00000002132.6 UniProtKB/TrEMBL
InterPro KRTAP_PMG UniProtKB/TrEMBL
KEGG Report rno:501768 UniProtKB/TrEMBL
NCBI Gene 501768 ENTREZGENE
Pfam PMG UniProtKB/TrEMBL
PhenoGen Krtap14 PhenoGen
RatGTEx ENSRNOG00000001567 RatGTEx
UniProt A6JLA2 ENTREZGENE, UniProtKB/TrEMBL
  M0R933 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Krtap14  keratin associated protein 14  RGD1564302_predicted  similar to anagen-specific protein mKAP13 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564302_predicted  similar to anagen-specific protein mKAP13 (predicted)  LOC501768  similar to anagen-specific protein mKAP13  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC501768  similar to anagen-specific protein mKAP13      Symbol and Name status set to provisional 70820 PROVISIONAL