Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Tusc2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TUSC2 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | ISO | Tusc2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TUSC2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Tusc2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TUSC2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tusc2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TUSC2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Tusc2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TUSC2 mRNA | CTD | PMID:21354282 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Tusc2 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of TUSC2 mRNA | CTD | PMID:20188158 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | TUSC2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TUSC2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TUSC2 mRNA | CTD | PMID:28628672 | aflatoxin B1 | increases methylation | ISO | TUSC2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of TUSC2 gene | CTD | PMID:27153756 | arsenite(3-) | multiple interactions | ISO | TUSC2 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to TUSC2 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases methylation | ISO | TUSC2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TUSC2 promoter | CTD | PMID:27901495 | benzo[b]fluoranthene | increases expression | ISO | Tusc2 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of TUSC2 mRNA | CTD | PMID:26377693 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TUSC2 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Tusc2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of TUSC2 mRNA | CTD | PMID:33221593 | bisphenol A | multiple interactions | ISO | TUSC2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TUSC2 mRNA | CTD | PMID:28628672 | bisphenol F | multiple interactions | ISO | TUSC2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TUSC2 mRNA | CTD | PMID:28628672 | cadmium atom | decreases expression | ISO | TUSC2 (Homo sapiens) | 6480464 | Cadmium results in decreased expression of TUSC2 mRNA | CTD | PMID:24284285 | chlorpyrifos | increases expression | ISO | Tusc2 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of TUSC2 mRNA | CTD | PMID:37019170 | cisplatin | increases expression | ISO | TUSC2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of TUSC2 mRNA | CTD | PMID:24280081 and PMID:27392435 | cisplatin | increases expression | ISO | Tusc2 (Mus musculus) | 6480464 | Cisplatin results in increased expression of TUSC2 mRNA | CTD | PMID:24280081 | copper(II) sulfate | decreases expression | ISO | TUSC2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of TUSC2 mRNA | CTD | PMID:19549813 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of TUSC2 mRNA | CTD | PMID:26577399 | dexamethasone | multiple interactions | ISO | TUSC2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TUSC2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TUSC2 mRNA | CTD | PMID:28628672 | disodium selenite | increases expression | ISO | TUSC2 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of TUSC2 mRNA | CTD | PMID:18175754 | ethyl methanesulfonate | increases expression | ISO | TUSC2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of TUSC2 mRNA | CTD | PMID:23649840 | fenthion | increases expression | ISO | Tusc2 (Mus musculus) | 6480464 | Fenthion results in increased expression of TUSC2 mRNA | CTD | PMID:34813904 | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of TUSC2 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Tusc2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TUSC2 mRNA | CTD | PMID:22206623 | FR900359 | affects phosphorylation | ISO | TUSC2 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of TUSC2 protein | CTD | PMID:37730182 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of TUSC2 mRNA | CTD | PMID:33387578 | indometacin | multiple interactions | ISO | TUSC2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TUSC2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TUSC2 mRNA | CTD | PMID:28628672 | leflunomide | decreases expression | ISO | TUSC2 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of TUSC2 mRNA | CTD | PMID:28988120 and PMID:29427785 | malathion | decreases expression | ISO | TUSC2 (Homo sapiens) | 6480464 | Malathion results in decreased expression of TUSC2 mRNA | CTD | PMID:32069766 | methyl methanesulfonate | increases expression | ISO | TUSC2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of TUSC2 mRNA | CTD | PMID:23649840 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of TUSC2 mRNA | CTD | PMID:25729387 | paracetamol | affects expression | ISO | Tusc2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TUSC2 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TUSC2 mRNA | CTD | PMID:33387578 | pirinixic acid | increases expression | ISO | Tusc2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of TUSC2 mRNA | CTD | PMID:18301758 and PMID:23811191 | sulindac | increases expression | EXP | | 6480464 | Sulindac results in increased expression of TUSC2 mRNA | CTD | PMID:24136188 | sunitinib | increases expression | ISO | TUSC2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of TUSC2 mRNA | CTD | PMID:31533062 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of TUSC2 mRNA | CTD | PMID:25729387 | valproic acid | affects expression | ISO | Tusc2 (Mus musculus) | 6480464 | Valproic Acid affects the expression of TUSC2 mRNA | CTD | PMID:17963808 | valproic acid | increases expression | ISO | TUSC2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TUSC2 mRNA | CTD | PMID:23179753 more ... | valproic acid | affects expression | ISO | TUSC2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TUSC2 mRNA | CTD | PMID:25979313 | vorinostat | increases expression | ISO | TUSC2 (Homo sapiens) | 6480464 | vorinostat results in increased expression of TUSC2 protein | CTD | PMID:20543569 | |