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Gene: Sik2 (salt-inducible kinase 2) Rattus norvegicus
Symbol: Sik2
Name: salt-inducible kinase 2
Description: Predicted to have ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including insulin receptor signaling pathway; protein autophosphorylation; and regulation of insulin receptor signaling pathway. Predicted to localize to the cytoplasm and nucleus. Orthologous to human SIK2 (salt inducible kinase 2); INTERACTS WITH bisphenol A; gentamycin; indole-3-methanol.
Type: gene
RefSeq Status: MODEL
Also known as: LOC315649; RGD1559698; similar to salt inducible kinase 2; SNF1-like kinase 2; Snf1lk2
Homo sapiens (human) : SIK2 (salt inducible kinase 2)  HGNC  Alliance
Mus musculus (house mouse) : Sik2 (salt inducible kinase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sik2 (salt inducible kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SIK2 (salt inducible kinase 2)
Canis lupus familiaris (dog) : SIK2 (salt inducible kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sik2 (salt inducible kinase 2)
Sus scrofa (pig) : SIK2 (salt inducible kinase 2)
more info ...
Allele / Splice: Sik2em4Mcwi   Sik2em5Mcwi  
Genetic Models: WKY-Sik2em5Mcwi WKY-Sik2em4Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0855,309,005 - 55,408,608 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl855,308,757 - 55,408,464 (-)Ensembl
Rnor_5.0853,905,730 - 54,005,295 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4854,240,307 - 54,337,976 (-)NCBIRGSC3.4rn4RGSC3.4
Celera850,772,712 - 50,871,786 (-)NCBICelera
Cytogenetic Map8q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Sik2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1559698
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.