Ugt1a3 (UDP glycosyltransferase 1 family, polypeptide A3)

Gene: Ugt1a3 (UDP glycosyltransferase 1 family, polypeptide A3) Rattus norvegicus

Analyze

Symbol:

Ugt1a3 (Ensembl: Ugt1a8)

Name:

UDP glycosyltransferase 1 family, polypeptide A3 (Ensembl:UDP glucuronosyltransferase family 1 member A8)

RGD ID:

1549728

Description:

Predicted to enable enzyme binding activity and glucuronosyltransferase activity. Involved in animal organ regeneration. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human UGT1A5 (UDP glucuronosyltransferase family 1 member A5); PARTICIPATES IN ascorbate and aldarate metabolic pathway; O-linked glycan biosynthetic pathway; pentose and glucuronate interconversion pathway; INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

B3; UDP glycosyltransferase 1 family polypeptide A3; UDP glycosyltransferase 1 family polypeptide A4; UDP-glucuronosyltransferase 1-3; UDP-glucuronosyltransferase 1A3; UDPGT; UDPGT 1-3; Ugt1; UGT1*3; UGT1-03; UGT1.3; Ugt1a4

RGD Orthologs

Human

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UGT1A5 (UDP glucuronosyltransferase family 1 member A5)	HGNC	HomoloGene
Other homologs ²
Homo sapiens (human):	UGT1A4 (UDP glucuronosyltransferase family 1 member A4)	HGNC	Panther
Homo sapiens (human):	UGT1A3 (UDP glucuronosyltransferase family 1 member A3)	HGNC	Panther
Alliance orthologs ³
Homo sapiens (human):	UGT1A5 (UDP glucuronosyltransferase family 1 member A5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ugt1a7 (UDP glucuronosyltransferase 1 family, polypeptide A7)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ugt1ab (UDP glucuronosyltransferase 1 family a, b)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG10168	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG10170	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder)
Drosophila melanogaster (fruit fly):	CG10178	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ugt-22	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA)
Caenorhabditis elegans (roundworm):	ugt-26	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG16732	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder)
Caenorhabditis elegans (roundworm):	ugt-62	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG17322	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder)
Drosophila melanogaster (fruit fly):	CG17323	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder)
Drosophila melanogaster (fruit fly):	CG17324	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ATG26	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	Ugt37c1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder)
Drosophila melanogaster (fruit fly):	Ugt35b	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Ugt86Dc	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Ugt86De	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Ugt86Dj	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG4302	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG6475	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Dot	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder)
Drosophila melanogaster (fruit fly):	Ugt86Dh	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Ugt86Di	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG5724	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder)
Drosophila melanogaster (fruit fly):	CG5999	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder)
Drosophila melanogaster (fruit fly):	Ugt37b1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder)
Drosophila melanogaster (fruit fly):	Ugt36Bb	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder)
Drosophila melanogaster (fruit fly):	CG3797	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder)
Drosophila melanogaster (fruit fly):	Ugt35a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Ugt36Bc	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder)
Drosophila melanogaster (fruit fly):	Ugt86Da	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ugt1a1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	96,228,134 - 96,256,264 (+)	NCBI		GRCr8
mRatBN7.2	9	88,780,328 - 88,808,465 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	88,713,184 - 88,808,465 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	97,204,156 - 97,232,360 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	102,340,349 - 102,368,552 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	100,708,528 - 100,736,659 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	95,274,707 - 95,302,822 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	95,161,157 - 95,302,822 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	94,961,922 - 94,990,037 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	87,070,247 - 87,098,362 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	9	86,341,626 - 86,369,556 (+)	NCBI		Celera
Cytogenetic Map	9	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

bilirubin metabolic disorder (ISO)

Crigler Najjar Syndrome, Type 2 (ISO)

Crigler-Najjar syndrome (ISO)

genetic disease (ISO)

Gilbert syndrome (ISO)

Hyperbilirubinemia, Transient Familial Neonatal (ISO)

Joubert syndrome 22 (ISO)

Perlman syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-methylcholanthrene (ISO)

3H-1,2-dithiole-3-thione (EXP)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (ISO)

9-cis-retinoic acid (EXP)

alpha-hexachlorocyclohexane (EXP)

ammonium chloride (EXP)

Aroclor 1254 (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP)

clofibrate (EXP)

ethanol (EXP)

furan (EXP)

glutathione (EXP)

morin (EXP)

nitrofen (EXP)

Nor-9-carboxy-delta9-THC (ISO)

omeprazole (ISO)

paracetamol (EXP)

perfluorooctanoic acid (EXP)

phenobarbital (EXP)

pregnenolone 16alpha-carbonitrile (EXP,ISO)

sevoflurane (EXP)

sodium arsenite (ISO)

spironolactone (EXP)

tetrachloromethane (EXP)

thyroxine (EXP)

tributylstannane (EXP)

trichloroethene (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

animal organ regeneration (IEP)

bile acid secretion (ISS)

cellular glucuronidation (IBA,ISS)

estrogen metabolic process (ISS)

vitamin D3 metabolic process (ISS)

xenobiotic glucuronidation (ISS)

Cellular Component

endoplasmic reticulum (IBA)

endoplasmic reticulum membrane (IEA)

Molecular Function

enzyme binding (IBA)

glucuronosyltransferase activity (IEA,ISS)

Molecular Pathway Annotations Click to see Annotation Detail View

ascorbate and aldarate metabolic pathway (IEA)

O-linked glycan biosynthetic pathway (IEA)

pentose and glucuronate interconversion pathway (IEA)

phase I biotransformation pathway via cytochrome P450 (IEA)

porphyrin and chlorophyll metabolic pathway (IEA)

retinol metabolic pathway (IEA)

starch and sucrose metabolic pathway (IEA)

steroid hormone biosynthetic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Comprehensive gene review and curation	RGD comprehensive gene curation
6.	Activity and expression of various isoforms of uridine diphosphate glucuronosyltransferase are differentially regulated during hepatic regeneration in rats.	Tian H, etal., Pharm Res. 2005 Dec;22(12):2007-15. Epub 2005 Oct 21.
7.	Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.	Zhang T, etal., Genome Res 2004 Jan;14(1):79-89. Epub 2003 Dec 12.

Additional References at PubMed

PMID:2112380	PMID:7608130	PMID:16141793

Genomics

Comparative Map Data

Ugt1a3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	96,228,134 - 96,256,264 (+)	NCBI		GRCr8
mRatBN7.2	9	88,780,328 - 88,808,465 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	88,713,184 - 88,808,465 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	97,204,156 - 97,232,360 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	102,340,349 - 102,368,552 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	100,708,528 - 100,736,659 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	95,274,707 - 95,302,822 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	95,161,157 - 95,302,822 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	94,961,922 - 94,990,037 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	87,070,247 - 87,098,362 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	9	86,341,626 - 86,369,556 (+)	NCBI		Celera
Cytogenetic Map	9	q35	NCBI

UGT1A5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	233,712,907 - 233,773,300 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	233,712,907 - 233,773,300 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	234,621,553 - 234,681,946 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	234,286,377 - 234,346,684 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	234,403,637 - 234,463,945	NCBI
Celera	2	228,342,257 - 228,402,577 (+)	NCBI		Celera
Cytogenetic Map	2	q37.1	NCBI
HuRef	2	226,421,632 - 226,481,779 (+)	NCBI		HuRef
CHM1_1	2	234,627,452 - 234,682,899 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	234,201,556 - 234,261,929 (+)	NCBI		T2T-CHM13v2.0

Variants

Variants in Ugt1a3
160 total Variants

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	48598251	93598251	Rat
4889852	Pur26	Proteinuria QTL 26	15	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	77813894	101597663	Rat
4889943	Bss90	Bone structure and strength QTL 90	4.1		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	9	86369631	92058970	Rat
7794784	Mcs31	Mammary carcinoma susceptibility QTL 31	2.98		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	9	77813894	111552878	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	36962359	92058970	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	61381434	104821652	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	75712843	111552878	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	62072275	96470995	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	62072275	96470995	Rat
61385	Edpm9	Estrogen-dependent pituitary mass QTL 9	3.43	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	63869687	108869687	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	58163035	100929646	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
2303178	Bp334	Blood pressure QTL 334	3.7	0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	79271511	91616855	Rat
2303178	Bp334	Blood pressure QTL 334	3.7	0.01	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	9	79271511	91616855	Rat
2303178	Bp334	Blood pressure QTL 334	3.7	0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	79271511	91616855	Rat
12879506	Pur33	Proteinuria QTL 33			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	44649921	89649921	Rat
731171	Glom6	Glomerulus QTL 6	2.8	0.0003	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	9	64573531	109573531	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	56771635	101771635	Rat
724547	Cm21	Cardiac mass QTL 21	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	9	79271511	102910209	Rat
11353951	Bp394	Blood pressure QTL 394			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	44649921	89649921	Rat
11353957	Bmd92	Bone mineral density QTL 92		0.01	tibia mineral mass (VT:1000283)	volumetric bone mineral density (CMO:0001553)	9	46114199	91114199	Rat

Markers in Region

D9Mco15

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	88,786,718 - 88,787,007 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	95,281,097 - 95,281,383	NCBI	Rnor6.0
Rnor_5.0	9	94,968,312 - 94,968,598	UniSTS	Rnor5.0
RGSC_v3.4	9	87,076,637 - 87,076,923	UniSTS	RGSC3.4
Celera	9	86,348,016 - 86,348,299	UniSTS
Cytogenetic Map	9	q35	UniSTS

D9Wox40

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	88,786,755 - 88,786,956 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	95,281,134 - 95,281,332	NCBI	Rnor6.0
Rnor_5.0	9	94,968,349 - 94,968,547	UniSTS	Rnor5.0
RGSC_v3.4	9	87,076,674 - 87,076,872	UniSTS	RGSC3.4
Celera	9	86,348,053 - 86,348,248	UniSTS
Cytogenetic Map	9	q35	UniSTS

RH130767

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	88,795,599 - 88,795,779 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	95,289,976 - 95,290,155	NCBI	Rnor6.0
Rnor_5.0	9	94,977,191 - 94,977,370	UniSTS	Rnor5.0
RGSC_v3.4	9	87,085,516 - 87,085,695	UniSTS	RGSC3.4
Celera	9	86,356,892 - 86,357,071	UniSTS
Cytogenetic Map	9	q35	UniSTS
Cytogenetic Map	9	q35-q36	UniSTS

RH94830

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	88,808,140 - 88,808,341 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	95,302,498 - 95,302,698	NCBI	Rnor6.0
Rnor_5.0	9	94,989,713 - 94,989,913	UniSTS	Rnor5.0
RGSC_v3.4	9	87,098,038 - 87,098,238	UniSTS	RGSC3.4
Celera	9	86,369,232 - 86,369,432	UniSTS
Cytogenetic Map	9	q35	UniSTS
Cytogenetic Map	9	q35-q36	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_201424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC092531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC120922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY435131	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D38067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

NM_201424 ⟹ NP_958827

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	96,228,134 - 96,256,264 (+)	NCBI
mRatBN7.2	9	88,780,328 - 88,808,465 (+)	NCBI
Rnor_6.0	9	95,274,707 - 95,302,822 (+)	NCBI
Rnor_5.0	9	94,961,922 - 94,990,037 (+)	NCBI
RGSC_v3.4	9	87,070,247 - 87,098,362 (+)	RGD
Celera	9	86,341,626 - 86,369,556 (+)	RGD

Sequence:

show sequence

ATGGGAATCCAAGGGTTCCTGCAGAAACTCTCAGGACTGCTGCTCCTGCTGTGTGCCCTGCCCT
GGGCTGAAGGTGGAAAGGTGCTGGTGTTTCCCATGGAGGGCAGCCACTGGCTGAGCATGAGGGA
TGTCGTGAGGGAGCTCCACGCCCGAGGTCACCAGGCTGTGGTCCTGGCTCCAGAGGTGACTGTG
CACATCAAAGAAGAGGACTTCTTCACCCTCCAAACCTACCCTGTTCCATACACCAAGGAAGAGT
ACAGGCACCACTTGCTGGGCCACCTTCAAAATTTTTTCGAAACTGAATTTTCTCTGAAGTTAGT
TCTACAGAGAATGGCAGCTGTAAATAACGTATCAACATTCTATGTGAGATCTTGCAGGGGTCTG
CTGCATAACACAGCTCTGATCCAGAGCCTGAACTCCAGCTCCTTCGATGTGGTTTTAACAGATC
CCTTTTTCCCCTGTGGGGCAGTGCTGGCCATGTACCTGCGTGTTCCTGCTGTGTTTTTTCTGCA
ATCCATGCTCTGTGAACTGGAATTTGAAGCAACAAACAGTCCAAACCCTTCTTCTTATATTCCC
AGGTTACTAACATTGAATTCTGACCACATGAGCTTCCTAGACAGAGTGAAGAATATGCTTTATC
CTGTGCCATGGATGTATTTATGCCATGTTAATTATGGCTCTCTGGCGAGACTTGCGTCAGACCT
TTTGCAGAGGGAGGTATCCGTGGTAGAGATCCTCAGACATGCCTCTGTATGGCTGTTGAGAAAG
GACTTTGTGTTCTACTACCCCAGGCCCTTCATGCCCAACATGGTCTTCATTGGGGGCATAAACT
GTGCCAACAGGAAGCCACTGTCTCAGGAATTTGAAGCCTATGTCAACGCCTCCGGAGAACATGG
CATCGTGGTTTTCTCTTTGGGATCCATGGTCTCAGAGATTCCAGAGAAGAAAGCGATGGAAATT
GCTGAGGCTTTGGGCAGAATTCCTCAGACGGTCCTGTGGCGCTACACCGGAACTAGACCATCGA
ACCTTGCAAAGAACACTATTCTTGTCAAATGGCTACCCCAAAACGATCTGCTTGGTCATCCAAA
GGCTCGGGCGTTCATCACACACTCCGGTTCCCATGGTATTTATGAAGGAATATGCAATGGGGTT
CCAATGGTGATGATGCCCTTGTTTGGTGATCAGATGGACAACGCCAAGCGCATGGAAACTCGGG
GAGCTGGGGTGACCCTGAATGTCCTGGAAATGACTGCCGATGATTTGGAAAACGCCCTTAAAAC
TGTCATCAATAACAAGAGTTACAAGGAGAACATCATGCGCCTCTCCAGCCTTCACAAGGACCGT
CCTATCGAGCCTCTGGACCTGGCTGTGTTCTGGGTGGAGTACGTGATGAGGCACAAGGGGGCGC
CACACCTGCGCCCCGCCGCCCACGACCTCACCTGGTACCAGTACCACTCCTTGGACGTGATTGG
CTTTCTCCTGGCCATCGTGTTGACGGTGGTCTTCATTGTCTATAAAAGTTGTGCCTATGGCTGC
CGGAAATGCTTTGGGGGAAAGGGTCGAGTGAAGAAATCACACAAATCCAAGACCCACTGAGAAG
TGGCAGGAAGTGAAGGAGAAGTATTAGTCCCTTATCCAATCAGTTGAAACTTGGAAACAAGTGT
TAAATCCATGTTGCTTTTATTAGGGAAATAATTCACCATACACTATACACCCAGAACAATTTTT
TTTCTTTTTCTTTTTTTCGGAGCTGGGGACCGAACCCAGAACATTTTTTTTTTTAAATAAAAAC
AATCTAATTGCTGGCCACACCCATCAGGGAAGATACTGGAATATGTGATCTGTTTCTCCAGTAT
CTTCAGTCTGGACAATGACTGCCATCTGTTGGTAACTTACAGAAAGTTTAGTGTTCTGCCTTCA
GTGACAGCACCACAGTTTCCCTTACTCCTGTCAGCTAATGGCTTCCTCCCCTGGATTCTCAGAC
CAGTGTGGCCTTCCCAGTGTTAGTCATTCCTCACTGTGCTCATGTTTTGTGGGTGGCACGGCCT
TTGAGCTTTGGGAGAAAAGAAGATGAGGCTGTGACACTGGTGGCCCTGTGTTTGAGATAATAAT
TATTGCTTGTCTCTGAATTTGATGAAAACTGAAGTACATTCTAAAGAAAGTATGTCTTCTATTG
TGTTCCCAAACCAAGAACTTGTCAATAAATTCATATAAATTGTATTATTACTTTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_958827	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAR95632	(Get FASTA)	NCBI Sequence Viewer
	BAA07262	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000046507
	ENSRNOP00000046507.3
	ENSRNOP00000063634.3
GenBank Protein	Q64637	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_958827 ⟸ NM_201424
- Peptide Label:	precursor
- UniProtKB:	Q64637 (UniProtKB/Swiss-Prot), Q6T5F1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGIQGFLQKLSGLLLLLCALPWAEGGKVLVFPMEGSHWLSMRDVVRELHARGHQAVVLAPEVTV HIKEEDFFTLQTYPVPYTKEEYRHHLLGHLQNFFETEFSLKLVLQRMAAVNNVSTFYVRSCRGL LHNTALIQSLNSSSFDVVLTDPFFPCGAVLAMYLRVPAVFFLQSMLCELEFEATNSPNPSSYIP RLLTLNSDHMSFLDRVKNMLYPVPWMYLCHVNYGSLARLASDLLQREVSVVEILRHASVWLLRK DFVFYYPRPFMPNMVFIGGINCANRKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEI AEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGV PMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDR PIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGC RKCFGGKGRVKKSHKSKTH hide sequence

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q64637-F1-model_v2	AlphaFold	Q64637	1-531	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1549728	AgrOrtholog
BioCyc Gene	G2FUF-26819	BioCyc
Ensembl Genes	ENSRNOG00000018740	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000045163	ENTREZGENE
	ENSRNOT00000045163.7	UniProtKB/TrEMBL
	ENSRNOT00000066839.5	UniProtKB/TrEMBL
Gene3D-CATH	Glycogen Phosphorylase B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	UDP_glucos_trans	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	UDP_glycos_trans_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:396551	UniProtKB/TrEMBL
NCBI Gene	396551	ENTREZGENE
PANTHER	EG:EG0003.4 PROTEIN-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	UDP GLUCURONOSYLTRANSFERASE 1 FAMILY POLYPEPTIDE A3 PRECURSOR-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	UDPGT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ugt1a3	PhenoGen
PROSITE	UDPGT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000018740	RatGTEx
Superfamily-SCOP	UDP-Glycosyltransferase/glycogen phosphorylase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	F7EKA4_RAT	UniProtKB/TrEMBL
	Q64637	ENTREZGENE
	Q6T5F1	ENTREZGENE, UniProtKB/TrEMBL
	UD13_RAT	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2009-12-22	Ugt1a3	UDP glycosyltransferase 1 family, polypeptide A3	Ugt1a3	UDP glycosyltransferase 1 family polypeptide A3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-08	Ugt1a3	UDP glycosyltransferase 1 family polypeptide A3	Ugt1a4	UDP glycosyltransferase 1 family polypeptide A4	Symbol and Name updated to reflect Human and Mouse nomenclature	1299863	APPROVED
2005-09-15	Ugt1a4	UDP glycosyltransferase 1 family polypeptide A4			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)