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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:1323139 | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of CERS5 mRNA | CTD | PMID:22206623 | 1,3-dinitrobenzene | increases expression | EXP | | 6480464 | 3-dinitrobenzene results in increased expression of CERS5 mRNA | CTD | PMID:21983209 | 17alpha-ethynylestradiol | affects expression | ISO | RGD:1323139 | 6480464 | Ethinyl Estradiol affects the expression of CERS5 mRNA | CTD | PMID:17555576 | 2,2',4,4',5,5'-hexachlorobiphenyl | increases expression | ISO | RGD:1323138 | 6480464 | 2 more ... | CTD | PMID:34627992 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1323139 | 6480464 | Tetrachlorodibenzodioxin affects the expression of CERS5 mRNA | CTD | PMID:21570461, PMID:24058054 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1323139 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CERS5 mRNA | CTD | PMID:28238261 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of CERS5 mRNA | CTD | PMID:22298810 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | RGD:1323139 | 6480464 | 4, 4'-diaminodiphenylmethane results in decreased expression of CERS5 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of CERS5 mRNA | CTD | PMID:36041667 | 4-amino-2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 4-amino-2, 6-dinitrotoluene affects the expression of CERS5 mRNA | CTD | PMID:21346803 | 4-hydroxyphenyl retinamide | decreases expression | ISO | RGD:1323139 | 6480464 | Fenretinide results in decreased expression of CERS5 mRNA | CTD | PMID:28973697 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of CERS5 mRNA | CTD | PMID:31881176 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of CERS5 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | ISO | RGD:1323138 | 6480464 | Aflatoxin B1 results in increased expression of CERS5 mRNA | CTD | PMID:21632981, PMID:22100608 | Aflatoxin B2 alpha | decreases methylation | ISO | RGD:1323138 | 6480464 | aflatoxin B2 results in decreased methylation of CERS5 intron | CTD | PMID:30157460 | atrazine | decreases expression | ISO | RGD:1323138 | 6480464 | Atrazine results in decreased expression of CERS5 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases expression | ISO | RGD:1323138 | 6480464 | Benzo(a)pyrene results in increased expression of CERS5 mRNA | CTD | PMID:20106945, PMID:21632981 | benzo[a]pyrene | increases methylation | ISO | RGD:1323139 | 6480464 | Benzo(a)pyrene results in increased methylation of CERS5 exon, Benzo(a)pyrene results in increased methylation of CERS5 intron | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | RGD:1323138 | 6480464 | Benzo(a)pyrene results in increased methylation of CERS5 3' UTR | CTD | PMID:27901495 | benzo[e]pyrene | decreases methylation | ISO | RGD:1323138 | 6480464 | benzo(e)pyrene results in decreased methylation of CERS5 intron | CTD | PMID:30157460 | bisphenol A | affects methylation | ISO | RGD:1323139 | 6480464 | bisphenol A affects the methylation of CERS5 promoter | CTD | PMID:27334623 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of CERS5 mRNA | CTD | PMID:36041667 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CERS5 mRNA | CTD | PMID:34947998 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of CERS5 mRNA | CTD | PMID:36041667 | cadmium dichloride | affects expression | ISO | RGD:1323138 | 6480464 | Cadmium Chloride affects the expression of CERS5 mRNA | CTD | PMID:25596134 | chloroacetaldehyde | increases expression | ISO | RGD:1323138 | 6480464 | chloroacetaldehyde results in increased expression of CERS5 mRNA | CTD | PMID:25596134 | choline | multiple interactions | ISO | RGD:1323139 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CERS5 gene | CTD | PMID:20938992 | cidofovir anhydrous | increases expression | ISO | RGD:1323138 | 6480464 | Cidofovir results in increased expression of CERS5 mRNA | CTD | PMID:25596134 | cisplatin | increases expression | ISO | RGD:1323138 | 6480464 | Cisplatin results in increased expression of CERS5 mRNA | CTD | PMID:25596134, PMID:27392435 | clodronic acid | increases expression | ISO | RGD:1323138 | 6480464 | Clodronic Acid results in increased expression of CERS5 mRNA | CTD | PMID:25596134 | cyclosporin A | increases expression | ISO | RGD:1323138 | 6480464 | Cyclosporine results in increased expression of CERS5 mRNA | CTD | PMID:20106945, PMID:25562108 | dioxygen | increases expression | ISO | RGD:1323138 | 6480464 | Oxygen deficiency results in increased expression of CERS5 mRNA | CTD | PMID:25596134 | ethyl methanesulfonate | increases expression | ISO | RGD:1323138 | 6480464 | Ethyl Methanesulfonate results in increased expression of CERS5 mRNA | CTD | PMID:23649840 | fenofibrate | decreases expression | EXP | | 6480464 | Fenofibrate results in decreased expression of CERS5 mRNA | CTD | PMID:25596134 | folic acid | multiple interactions | ISO | RGD:1323139 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CERS5 gene | CTD | PMID:20938992 | formaldehyde | increases expression | ISO | RGD:1323138 | 6480464 | Formaldehyde results in increased expression of CERS5 mRNA | CTD | PMID:23649840 | hydralazine | multiple interactions | ISO | RGD:1323138 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of CERS5 mRNA | CTD | PMID:17183730 | ibuprofen | decreases expression | EXP | | 6480464 | Ibuprofen results in decreased expression of CERS5 mRNA | CTD | PMID:25596134 | ifosfamide | increases expression | ISO | RGD:1323138 | 6480464 | Ifosfamide results in increased expression of CERS5 mRNA | CTD | PMID:25596134 | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of CERS5 mRNA | CTD | PMID:21396975 | L-methionine | multiple interactions | ISO | RGD:1323139 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CERS5 gene | CTD | PMID:20938992 | metformin | increases expression | EXP | | 6480464 | Metformin results in increased expression of CERS5 mRNA | CTD | PMID:25596134 | methapyrilene | decreases methylation | ISO | RGD:1323138 | 6480464 | Methapyrilene results in decreased methylation of CERS5 intron | CTD | PMID:30157460 | methotrexate | affects expression | ISO | RGD:1323139 | 6480464 | Methotrexate affects the expression of CERS5 mRNA | CTD | PMID:18502557 | methotrexate | increases expression | ISO | RGD:1323138 | 6480464 | Methotrexate results in increased expression of CERS5 mRNA | CTD | PMID:24449571 | methyl methanesulfonate | increases expression | ISO | RGD:1323138 | 6480464 | Methyl Methanesulfonate results in increased expression of CERS5 mRNA | CTD | PMID:23649840 | paracetamol | affects expression | ISO | RGD:1323139 | 6480464 | Acetaminophen affects the expression of CERS5 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | RGD:1323138 | 6480464 | Acetaminophen results in increased expression of CERS5 mRNA | CTD | PMID:29067470 | pirinixic acid | multiple interactions | ISO | RGD:1323138 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CERS5 mRNA | CTD | PMID:19710929 | quercetin | increases expression | ISO | RGD:1323138 | 6480464 | Quercetin results in increased expression of CERS5 mRNA | CTD | PMID:21632981 | quercitrin | increases expression | ISO | RGD:1323138 | 6480464 | quercitrin results in increased expression of CERS5 mRNA | CTD | PMID:25193878 | resveratrol | multiple interactions | ISO | RGD:1323138 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of CERS5 mRNA | CTD | PMID:23557933 | temozolomide | increases expression | ISO | RGD:1323138 | 6480464 | Temozolomide results in increased expression of CERS5 mRNA | CTD | PMID:31758290 | tetracycline | increases expression | ISO | RGD:1323139 | 6480464 | Tetracycline results in increased expression of CERS5 mRNA | CTD | PMID:16917069 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of CERS5 mRNA | CTD | PMID:23411599 | valproic acid | multiple interactions | ISO | RGD:1323138 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of CERS5 mRNA | CTD | PMID:17183730 | |