Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | SAP18 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SAP18 mRNA | CTD | PMID:22079256 | 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | increases expression | EXP | | 6480464 | o and p'-DDT results in increased expression of SAP18 mRNA | CTD | PMID:24096037 | 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | increases expression | ISO | Sap18 (Mus musculus) | 6480464 | o and p'-DDT results in increased expression of SAP18 mRNA | CTD | PMID:24096037 | 1,2-dimethylhydrazine | multiple interactions | ISO | Sap18 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SAP18 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Sap18 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SAP18 mRNA | CTD | PMID:22206623 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | multiple interactions | ISO | Sap18 (Mus musculus) | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | increases expression | ISO | Sap18 (Mus musculus) | 6480464 | 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 17alpha-ethynylestradiol | increases expression | ISO | Sap18 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of SAP18 mRNA | CTD | PMID:17942748 and PMID:24096037 | 17alpha-ethynylestradiol | affects expression | ISO | Sap18 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of SAP18 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of SAP18 mRNA | CTD | PMID:24096037 | 17alpha-ethynylestradiol | multiple interactions | ISO | Sap18 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SAP18 mRNA | CTD | PMID:17942748 | 17beta-estradiol | decreases expression | ISO | SAP18 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of SAP18 mRNA | CTD | PMID:15223131 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | SAP18 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Sap18 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SAP18 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SAP18 mRNA | CTD | PMID:21724226 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Sap18 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SAP18 mRNA | CTD | PMID:17942748 | 2,4,6-tribromophenol | decreases expression | ISO | SAP18 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of SAP18 mRNA | CTD | PMID:21346803 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | SAP18 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of SAP18 protein | CTD | PMID:31675489 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SAP18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SAP18 mRNA | CTD | PMID:28628672 | acrylamide | increases expression | ISO | SAP18 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of SAP18 mRNA | CTD | PMID:32763439 | aristolochic acid A | increases expression | ISO | SAP18 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of SAP18 mRNA | CTD | PMID:33212167 | arsenite(3-) | multiple interactions | ISO | SAP18 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to SAP18 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases methylation | ISO | SAP18 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SAP18 promoter | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | increases expression | ISO | SAP18 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of SAP18 mRNA | CTD | PMID:25181051 more ... | bisphenol A | multiple interactions | ISO | SAP18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SAP18 mRNA | CTD | PMID:28628672 | bisphenol A | affects methylation | EXP | | 6480464 | bisphenol A affects the methylation of SAP18 promoter | CTD | PMID:27415467 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of SAP18 mRNA | CTD | PMID:19167457 | caffeine | multiple interactions | ISO | Sap18 (Mus musculus) | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | carbon nanotube | decreases expression | ISO | Sap18 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | chlorpyrifos | decreases expression | ISO | Sap18 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of SAP18 mRNA | CTD | PMID:37019170 | choline | multiple interactions | ISO | Sap18 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of SAP18 mRNA | CTD | PMID:20938992 | clobetasol | increases expression | ISO | Sap18 (Mus musculus) | 6480464 | Clobetasol results in increased expression of SAP18 mRNA | CTD | PMID:27462272 | copper atom | multiple interactions | ISO | SAP18 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of SAP18 mRNA | CTD | PMID:24690739 | copper(0) | multiple interactions | ISO | SAP18 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of SAP18 mRNA | CTD | PMID:24690739 | cyclosporin A | decreases expression | ISO | SAP18 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of SAP18 mRNA | CTD | PMID:25562108 | dexamethasone | multiple interactions | ISO | SAP18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SAP18 mRNA | CTD | PMID:28628672 | dicrotophos | decreases expression | ISO | SAP18 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of SAP18 mRNA | CTD | PMID:28302478 | disulfiram | multiple interactions | ISO | SAP18 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of SAP18 mRNA | CTD | PMID:24690739 | diuron | decreases expression | ISO | SAP18 (Homo sapiens) | 6480464 | Diuron results in decreased expression of SAP18 mRNA | CTD | PMID:35967413 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of SAP18 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Sap18 (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | folic acid | decreases expression | ISO | Sap18 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of SAP18 mRNA | CTD | PMID:25629700 | formaldehyde | increases expression | ISO | SAP18 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of SAP18 mRNA | CTD | PMID:23649840 | fulvestrant | increases methylation | ISO | SAP18 (Homo sapiens) | 6480464 | Fulvestrant results in increased methylation of SAP18 gene | CTD | PMID:31601247 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SAP18 mRNA | CTD | PMID:22061828 | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of SAP18 mRNA | CTD | PMID:24136188 | indometacin | multiple interactions | ISO | SAP18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of SAP18 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | SAP18 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SAP18 protein | CTD | PMID:32959892 | L-methionine | multiple interactions | ISO | Sap18 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of SAP18 mRNA | CTD | PMID:20938992 | lead(0) | decreases expression | ISO | SAP18 (Homo sapiens) | 6480464 | Lead results in decreased expression of SAP18 mRNA | CTD | PMID:19921347 | methamphetamine | decreases expression | EXP | | 6480464 | Methamphetamine results in decreased expression of SAP18 mRNA | CTD | PMID:32035215 | methyl methanesulfonate | increases expression | ISO | SAP18 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of SAP18 mRNA | CTD | PMID:23649840 | methylisothiazolinone | increases expression | ISO | SAP18 (Homo sapiens) | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of SAP18 mRNA | CTD | PMID:31629900 | miconazole | increases expression | ISO | Sap18 (Mus musculus) | 6480464 | Miconazole results in increased expression of SAP18 mRNA | CTD | PMID:27462272 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of SAP18 mRNA | CTD | PMID:24136188 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of SAP18 mRNA | CTD | PMID:24136188 | paracetamol | affects expression | ISO | Sap18 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SAP18 mRNA | CTD | PMID:17562736 | perfluorooctanoic acid | increases expression | ISO | Sap18 (Mus musculus) | 6480464 | perfluorooctanoic acid results in increased expression of SAP18 protein | CTD | PMID:37422089 | perfluorooctanoic acid | decreases expression | ISO | Sap18 (Mus musculus) | 6480464 | perfluorooctanoic acid results in decreased expression of SAP18 protein | CTD | PMID:36214631 | phenobarbital | affects expression | ISO | Sap18 (Mus musculus) | 6480464 | Phenobarbital affects the expression of SAP18 mRNA | CTD | PMID:23091169 | pirinixic acid | increases expression | ISO | Sap18 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of SAP18 mRNA | CTD | PMID:23811191 | potassium chromate | increases expression | ISO | SAP18 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of SAP18 mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | SAP18 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SAP18 mRNA | CTD | PMID:22079256 | propiconazole | decreases expression | ISO | Sap18 (Mus musculus) | 6480464 | propiconazole results in decreased expression of SAP18 mRNA | CTD | PMID:21278054 | quercetin | increases expression | ISO | SAP18 (Homo sapiens) | 6480464 | Quercetin results in increased expression of SAP18 mRNA | CTD | PMID:21632981 | quercitrin | increases expression | ISO | SAP18 (Homo sapiens) | 6480464 | quercitrin results in increased expression of SAP18 mRNA | CTD | PMID:25193878 | silver atom | decreases expression | ISO | Sap18 (Mus musculus) | 6480464 | Silver results in decreased expression of SAP18 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | Sap18 (Mus musculus) | 6480464 | Silver results in decreased expression of SAP18 mRNA | CTD | PMID:27131904 | succimer | multiple interactions | ISO | Sap18 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of SAP18 mRNA | CTD | PMID:21641980 | sunitinib | decreases expression | ISO | SAP18 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of SAP18 mRNA | CTD | PMID:31533062 | tamoxifen | affects expression | ISO | Sap18 (Mus musculus) | 6480464 | Tamoxifen affects the expression of SAP18 mRNA | CTD | PMID:17555576 | tert-butyl hydroperoxide | decreases expression | ISO | SAP18 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of SAP18 mRNA | CTD | PMID:15336504 | testosterone | decreases expression | ISO | Sap18 (Mus musculus) | 6480464 | Testosterone results in decreased expression of SAP18 mRNA | CTD | PMID:21669218 | tetrachloromethane | affects expression | ISO | Sap18 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of SAP18 mRNA | CTD | PMID:17484886 | thapsigargin | decreases expression | ISO | Sap18 (Mus musculus) | 6480464 | Thapsigargin results in decreased expression of SAP18 protein | CTD | PMID:24648495 | topotecan | affects response to substance | ISO | SAP18 (Homo sapiens) | 6480464 | SAP18 protein affects the susceptibility to Topotecan | CTD | PMID:16217747 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of SAP18 mRNA | CTD | PMID:33387578 | triptonide | increases expression | ISO | Sap18 (Mus musculus) | 6480464 | triptonide results in increased expression of SAP18 mRNA | CTD | PMID:33045310 | urethane | increases expression | ISO | SAP18 (Homo sapiens) | 6480464 | Urethane results in increased expression of SAP18 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | Sap18 (Mus musculus) | 6480464 | Valproic Acid affects the expression of SAP18 mRNA | CTD | PMID:17963808 | |