Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Shprh (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SHPRH mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | decreases expression | ISO | Shprh (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SHPRH mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Shprh (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SHPRH mRNA | CTD | PMID:19465110 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SHPRH mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Shprh (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SHPRH mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | SHPRH (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SHPRH mRNA | CTD | PMID:17101203 more ... | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Shprh (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of SHPRH mRNA | CTD | PMID:26251327 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SHPRH (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SHPRH mRNA | CTD | PMID:28628672 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of SHPRH mRNA | CTD | PMID:28959563 | acrylamide | decreases expression | ISO | SHPRH (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of SHPRH mRNA | CTD | PMID:32763439 | aflatoxin B1 | increases expression | ISO | Shprh (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of SHPRH mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases methylation | ISO | SHPRH (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of SHPRH gene | CTD | PMID:27153756 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of SHPRH mRNA | CTD | PMID:30779732 | aristolochic acid A | decreases expression | ISO | SHPRH (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SHPRH mRNA | CTD | PMID:33212167 | atrazine | decreases expression | ISO | SHPRH (Homo sapiens) | 6480464 | Atrazine results in decreased expression of SHPRH mRNA | CTD | PMID:22378314 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | SHPRH (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of SHPRH mRNA | CTD | PMID:25181051 | bisphenol A | increases methylation | ISO | SHPRH (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of SHPRH gene | CTD | PMID:31601247 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SHPRH mRNA | CTD | PMID:30816183 and PMID:34947998 | bisphenol A | multiple interactions | ISO | SHPRH (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SHPRH mRNA | CTD | PMID:28628672 | Bisphenol A diglycidyl ether | affects splicing | ISO | Shprh (Mus musculus) | 6480464 | 2 and 2-bis(4-glycidyloxyphenyl)propane affects the splicing of SHPRH mRNA | CTD | PMID:36464114 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of SHPRH promoter | CTD | PMID:22457795 | cadmium dichloride | decreases expression | ISO | Shprh (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of SHPRH mRNA | CTD | PMID:24982889 | CGP 52608 | multiple interactions | ISO | SHPRH (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SHPRH gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | ISO | Shprh (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of SHPRH mRNA | CTD | PMID:20350560 and PMID:37019170 | cisplatin | increases expression | ISO | Shprh (Mus musculus) | 6480464 | Cisplatin results in increased expression of SHPRH mRNA | CTD | PMID:21151649 | copper(II) sulfate | decreases expression | ISO | SHPRH (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of SHPRH mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | SHPRH (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of SHPRH mRNA | CTD | PMID:25562108 | dexamethasone | multiple interactions | ISO | SHPRH (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SHPRH mRNA | CTD | PMID:28628672 | dibutyl phthalate | decreases expression | ISO | Shprh (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of SHPRH mRNA | CTD | PMID:21266533 | diclofenac | decreases expression | ISO | Shprh (Mus musculus) | 6480464 | Diclofenac results in decreased expression of SHPRH mRNA | CTD | PMID:26934552 | ethanol | affects splicing | ISO | Shprh (Mus musculus) | 6480464 | Ethanol affects the splicing of SHPRH mRNA | CTD | PMID:30319688 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of SHPRH mRNA | CTD | PMID:30307764 | FR900359 | decreases phosphorylation | ISO | SHPRH (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of SHPRH protein | CTD | PMID:37730182 | hydrogen peroxide | affects expression | ISO | SHPRH (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of SHPRH mRNA | CTD | PMID:20044591 | hydrogen peroxide | multiple interactions | ISO | SHPRH (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SHPRH protein | CTD | PMID:18951874 | indometacin | multiple interactions | ISO | SHPRH (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SHPRH mRNA | CTD | PMID:28628672 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of SHPRH mRNA | CTD | PMID:30467583 | pentanal | decreases expression | ISO | SHPRH (Homo sapiens) | 6480464 | pentanal results in decreased expression of SHPRH mRNA | CTD | PMID:26079696 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | SHPRH (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of SHPRH mRNA | CTD | PMID:27153767 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Shprh (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SHPRH mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of SHPRH mRNA | CTD | PMID:36331819 | pirinixic acid | decreases expression | ISO | Shprh (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of SHPRH mRNA | CTD | PMID:18445702 | pirinixic acid | increases expression | ISO | Shprh (Mus musculus) | 6480464 | pirinixic acid results in increased expression of SHPRH mRNA | CTD | PMID:18301758 | potassium dichromate | decreases expression | ISO | Shprh (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of SHPRH mRNA | CTD | PMID:23608068 | quercetin | decreases expression | ISO | SHPRH (Homo sapiens) | 6480464 | Quercetin results in decreased expression of SHPRH mRNA | CTD | PMID:21632981 | quercetin | increases phosphorylation | ISO | SHPRH (Homo sapiens) | 6480464 | Quercetin results in increased phosphorylation of SHPRH protein | CTD | PMID:35688186 | resveratrol | multiple interactions | ISO | SHPRH (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of SHPRH mRNA | CTD | PMID:23557933 | silicon dioxide | decreases expression | ISO | Shprh (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of SHPRH mRNA | CTD | PMID:19073995 | sodium arsenite | decreases expression | ISO | Shprh (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of SHPRH mRNA | CTD | PMID:16014739 | theophylline | multiple interactions | ISO | SHPRH (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SHPRH protein | CTD | PMID:18951874 | titanium dioxide | increases expression | ISO | Shprh (Mus musculus) | 6480464 | titanium dioxide results in increased expression of SHPRH mRNA | CTD | PMID:29264374 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of SHPRH mRNA | CTD | PMID:33387578 | troglitazone | decreases expression | ISO | Shprh (Mus musculus) | 6480464 | troglitazone results in decreased expression of SHPRH mRNA | CTD | PMID:28973697 | valproic acid | increases expression | ISO | SHPRH (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SHPRH mRNA | CTD | PMID:29154799 | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of SHPRH mRNA | CTD | PMID:29427782 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of SHPRH mRNA | CTD | PMID:18042343 and PMID:20566332 | |