Man1a2 (mannosidase, alpha, class 1A, member 2)

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Gene: Man1a2 (mannosidase, alpha, class 1A, member 2) Rattus norvegicus

Analyze

Symbol:

Man1a2

Name:

mannosidase, alpha, class 1A, member 2

RGD ID:

1309767

Description:

Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in mannose trimming involved in glycoprotein ERAD pathway. Predicted to act upstream of or within glycoprotein metabolic process; lung alveolus development; and respiratory gaseous exchange by respiratory system. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi membrane and endoplasmic reticulum. Orthologous to human MAN1A2 (mannosidase alpha class 1A member 2); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC295319; Man1b; mannosidase 1, beta; mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MAN1A2 (mannosidase alpha class 1A member 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Man1a2 (mannosidase, alpha, class 1A, member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Man1a2 (mannosidase alpha class 1A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MAN1A2 (mannosidase alpha class 1A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MAN1A2 (mannosidase alpha class 1A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Man1a2 (mannosidase alpha class 1A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MAN1A2 (mannosidase alpha class 1A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MAN1A2 (mannosidase alpha class 1A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Man1a2 (mannosidase alpha class 1A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	MAN1A2 (mannosidase alpha class 1A member 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Man1a2 (mannosidase, alpha, class 1A, member 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	man1a2 (mannosidase, alpha, class 1A, member 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	alpha-Man-Ia	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mans-1	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mans-2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	alpha-Man-Ic	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	MNL2	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	man1a2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	187,947,484 - 188,096,332 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	187,951,617 - 188,096,332 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	195,591,655 - 195,737,181 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	2	193,440,991 - 193,586,292 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	2	188,259,512 - 188,404,801 (-)	NCBI	Rnor_WKY
Rnor_6.0	2	202,891,537 - 203,043,847 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	202,891,537 - 203,043,847 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	222,489,647 - 222,490,312 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	2	222,338,553 - 222,444,440 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	195,561,701 - 195,705,232 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	195,525,647 - 195,667,623 (-)	NCBI
Celera	2	180,396,514 - 180,540,574 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

acrolein (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

antimony(0) (ISO)

aristolochic acid A (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroacetaldehyde (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

cyclosporin A (EXP,ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dioxygen (ISO)

dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate (ISO)

dorsomorphin (ISO)

ethanol (ISO)

fenofibrate (EXP)

fenvalerate (EXP)

flutamide (EXP)

formaldehyde (ISO)

geldanamycin (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

hypochlorous acid (ISO)

indometacin (ISO)

ivermectin (ISO)

metformin (EXP)

methapyrilene (ISO)

methylmercury chloride (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenol (ISO)

phenylmercury acetate (ISO)

quercetin (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triptonide (ISO)

troglitazone (EXP)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

carbohydrate metabolic process (IEA)

glycoprotein metabolic process (ISO)

lung alveolus development (ISO)

mannose trimming involved in glycoprotein ERAD pathway (IBA)

respiratory gaseous exchange by respiratory system (ISO)

Cellular Component

endoplasmic reticulum (IBA)

Golgi apparatus (ISO)

Golgi membrane (IBA,ISO)

Molecular Function

calcium ion binding (IEA)

mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

Endoplasmic Reticulum-associated degradation pathway (IEA)

N-linked glycan biosynthetic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11042173	PMID:17121831	PMID:19199708	PMID:19946888

Genomics

Comparative Map Data

Man1a2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	187,947,484 - 188,096,332 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	187,951,617 - 188,096,332 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	195,591,655 - 195,737,181 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	2	193,440,991 - 193,586,292 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	2	188,259,512 - 188,404,801 (-)	NCBI	Rnor_WKY
Rnor_6.0	2	202,891,537 - 203,043,847 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	202,891,537 - 203,043,847 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	222,489,647 - 222,490,312 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	2	222,338,553 - 222,444,440 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	195,561,701 - 195,705,232 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	195,525,647 - 195,667,623 (-)	NCBI
Celera	2	180,396,514 - 180,540,574 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

MAN1A2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	117,367,449 - 117,528,872 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	1	117,367,449 - 117,528,872 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	117,910,071 - 118,071,494 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	117,711,608 - 117,869,843 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	117,622,126 - 117,780,362	NCBI
Celera	1	116,138,692 - 116,296,183 (+)	NCBI		Celera
Cytogenetic Map	1	p12	NCBI
HuRef	1	115,766,956 - 115,925,256 (+)	NCBI		HuRef
CHM1_1	1	118,024,915 - 118,183,335 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	117,376,496 - 117,538,299 (+)	NCBI		T2T-CHM13v2.0

Man1a2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	100,469,519 - 100,592,789 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	100,469,524 - 100,592,819 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	100,562,203 - 100,685,473 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	100,562,208 - 100,685,503 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	100,366,126 - 100,489,396 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	100,695,478 - 100,814,288 (-)	NCBI		MGSCv36	mm8
Celera	3	102,769,059 - 102,892,426 (-)	NCBI		Celera
Cytogenetic Map	3	F2.2	NCBI

Man1a2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955435	20,532,717 - 20,683,805 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955435	20,532,717 - 20,683,805 (+)	NCBI	ChiLan1.0	ChiLan1.0

MAN1A2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	1	109,620,892 - 109,780,512 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	84,993,586 - 85,153,199 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	119,988,895 - 120,148,561 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	119,994,812 - 120,148,623 (-)	Ensembl	panpan1.1		panPan2

MAN1A2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	54,697,507 - 54,908,305 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	54,697,324 - 54,904,607 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	54,341,882 - 54,554,835 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	55,576,802 - 55,790,408 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	55,577,342 - 55,764,738 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	54,612,523 - 54,825,251 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	54,649,914 - 54,863,228 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	55,224,869 - 55,438,002 (+)	NCBI		UU_Cfam_GSD_1.0

Man1a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	11,845,536 - 11,989,346 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936627	2,499,660 - 2,641,094 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936627	2,499,666 - 2,640,195 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAN1A2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	103,214,939 - 103,376,673 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	103,214,929 - 103,377,132 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	113,179,406 - 113,343,680 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MAN1A2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	16,199,418 - 16,364,688 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	16,201,781 - 16,364,962 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	18,868,491 - 19,037,306 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Man1a2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624772	13,103,855 - 13,253,408 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624772	13,103,698 - 13,253,215 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Man1a2
1025 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	358
Count of miRNA genes:	222
Interacting mature miRNAs:	262
Transcripts:	ENSRNOT00000067000
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	43154682	202446871	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	56043031	202447032	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118275	202447032	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118463	226797303	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	74786664	206665859	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	76539322	202447032	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	78665619	219826953	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	81689826	221035911	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	81754530	222436696	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	81754530	227146641	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	112456140	212696837	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	112456140	212696837	Rat
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	114837527	211674221	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	114837675	212549332	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	133914684	202447032	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	135552573	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	135552573	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	135552573	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	2	135552573	202446871	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	135552573	202446871	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	136445150	202447032	Rat
1581502	Esta3	Estrogen-induced thymic atrophy QTL 3			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	136916935	189599348	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	136916935	213594495	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	141194931	223265385	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	141194931	223265385	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	141596551	202447032	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	143157029	210020885	Rat
10043136	Iddm54	Insulin dependent diabetes mellitus QTL 54	3.4	0.0001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	143657411	190602963	Rat
10043136	Iddm54	Insulin dependent diabetes mellitus QTL 54	3.4	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	143657411	190602963	Rat
61401	Niddm2	Non-insulin dependent diabetes mellitus QTL 2	4.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	144599348	189599348	Rat
1598833	Bp295	Blood pressure QTL 295	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	147798556	192798556	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	221167075	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	249053267	Rat
1598805	Memor8	Memory QTL 8	3		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	150341585	189039377	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150341684	202446871	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150540301	202447032	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	150540301	202447032	Rat
1359032	Hrtrt18	Heart rate QTL 18			heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	157142078	192625452	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	157142078	211086598	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	157142078	226277316	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	157142209	202446871	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	160564068	205564068	Rat
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	161699179	222436696	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	162765032	207765032	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	164073756	227146641	Rat
1598838	Bp290	Blood pressure QTL 290	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166539266	211539266	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	168358098	223265385	Rat
2307174	Activ3	Activity QTL 3	4.83	0.000058	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	168594495	213594495	Rat
61469	Bp16	Blood pressure QTL 16	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
70162	Bp63	Blood pressure QTL 63	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
2293084	Iddm26	Insulin dependent diabetes mellitus QTL 26	2.9		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	174930955	213594495	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	179335906	224335906	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	179946951	224946951	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	182171407	227171407	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	182171407	227171407	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	182171407	227171407	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	182171407	227171407	Rat
4889834	Pur24	Proteinuria QTL 24	5.8	0.014	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	184114274	202447032	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	184165752	229165752	Rat
7488929	Bp366	Blood pressure QTL 366		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	184974550	193094998	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	185876309	219753474	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	185876309	219753474	Rat

Markers in Region

RH138306

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	188,078,539 - 188,078,683 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	203,024,944 - 203,025,087	NCBI	Rnor6.0
Rnor_5.0	2	222,472,721 - 222,472,864	UniSTS	Rnor5.0
RGSC_v3.4	2	195,687,061 - 195,687,204	UniSTS	RGSC3.4
Celera	2	180,522,786 - 180,522,929	UniSTS
RH 3.4 Map	2	1276.9	UniSTS
Cytogenetic Map	2	q34	UniSTS

AW532536

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	187,949,762 - 187,949,913 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	202,889,683 - 202,889,833	NCBI	Rnor6.0
Rnor_5.0	2	222,336,699 - 222,336,849	UniSTS	Rnor5.0
RGSC_v3.4	2	195,559,847 - 195,559,997	UniSTS	RGSC3.4
Celera	2	180,394,660 - 180,394,810	UniSTS
RH 3.4 Map	2	1279.5	UniSTS
Cytogenetic Map	2	q34	UniSTS

RH136810

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	187,950,689 - 187,950,855 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	202,890,610 - 202,890,775	NCBI	Rnor6.0
Rnor_5.0	2	222,337,626 - 222,337,791	UniSTS	Rnor5.0
RGSC_v3.4	2	195,560,774 - 195,560,939	UniSTS	RGSC3.4
Celera	2	180,395,587 - 180,395,752	UniSTS
RH 3.4 Map	2	1276.2	UniSTS
Cytogenetic Map	2	q34	UniSTS

RH139474

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	187,950,776 - 187,950,956 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	202,890,697 - 202,890,876	NCBI	Rnor6.0
Rnor_5.0	2	222,337,713 - 222,337,892	UniSTS	Rnor5.0
RGSC_v3.4	2	195,560,861 - 195,561,040	UniSTS	RGSC3.4
Celera	2	180,395,674 - 180,395,853	UniSTS
RH 3.4 Map	2	1274.3	UniSTS
Cytogenetic Map	2	q34	UniSTS

RH141555

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	187,951,827 - 187,952,047 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	202,891,748 - 202,891,967	NCBI	Rnor6.0
Rnor_5.0	2	222,338,764 - 222,338,983	UniSTS	Rnor5.0
RGSC_v3.4	2	195,561,912 - 195,562,131	UniSTS	RGSC3.4
Celera	2	180,396,725 - 180,396,944	UniSTS
RH 3.4 Map	2	1279.0	UniSTS
Cytogenetic Map	2	q34	UniSTS

AA945034

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	187,949,033 - 187,949,182 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	202,888,954 - 202,889,102	NCBI	Rnor6.0
Rnor_5.0	2	222,335,970 - 222,336,118	UniSTS	Rnor5.0
RGSC_v3.4	2	195,559,118 - 195,559,266	UniSTS	RGSC3.4
Celera	2	180,393,931 - 180,394,079	UniSTS
RH 3.4 Map	2	1275.8	UniSTS
Cytogenetic Map	2	q34	UniSTS

BQ195426

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	187,952,689 - 187,952,841 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	202,892,610 - 202,892,761	NCBI	Rnor6.0
Rnor_5.0	2	222,339,626 - 222,339,777	UniSTS	Rnor5.0
RGSC_v3.4	2	195,562,774 - 195,562,925	UniSTS	RGSC3.4
Celera	2	180,397,587 - 180,397,738	UniSTS
RH 3.4 Map	2	1228.6	UniSTS
Cytogenetic Map	2	q34	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	39	57	41	19	41	1	1	74	35	41	11	1
Low	1	4					7	10					7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106452	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000067000 ⟹ ENSRNOP00000060243

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	187,951,617 - 188,096,332 (-)	Ensembl
Rnor_6.0 Ensembl	2	202,891,537 - 203,043,847 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000105480 ⟹ ENSRNOP00000095157

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	187,952,810 - 188,096,332 (-)	Ensembl

RefSeq Acc Id:

NM_001106452 ⟹ NP_001099922

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	187,951,617 - 188,096,332 (-)	NCBI
Rnor_6.0	2	202,891,537 - 203,043,847 (-)	NCBI
Rnor_5.0	2	222,338,553 - 222,444,440 (-)	NCBI
Rnor_5.0	2	222,489,647 - 222,490,312 (-)	NCBI
RGSC_v3.4	2	195,561,701 - 195,705,232 (-)	RGD
Celera	2	180,396,514 - 180,540,574 (-)	RGD

Sequence:

show sequence

CATGGCAGAACCCACCTTGCAGCTTCTCTGCAGTGTGTTTCGCCCGGTCCGCTCTCGGGAATGA
AGAGGAGACTCGCGATCACCCGGTGAGGAACTGAGAGCCAAATGGCGAGAAGATCTTACCGGAC
AGAAATCAGCGATCGCTTGGGAGGTCACCCGGGCTTCTGGATGTAATCGGAGACCATGAAAGAG
GTGGCCTCGTAAATAATCATCATCATAATAAAAAAGCACAACAATCCTTTGAGAGGCGGGAAGT
TGAGTTTATTCATTTTTTTTGTCGAGGTTTTGAGAAACGGTTCGATGTGTTGTACATTTGATAT
AAGATGAGAACTTTATAAAGTATTCCGTCCAAGAGCCTAAACGATGACTACCCCAGCGCTGCTG
CCCCTGTCTGGTCGTAGGATACCACCTCTGAACCTGGGGCCGCCCTCCTTCCCACATCACAGGG
CTACCTTGAGACTCTCCGAGAAGTTTATCCTTCTCCTCATCCTTAGTGCCTTCATCACCCTGTG
TTTTGGGGCATTCTTCTTCCTTCCAGACTCTTCAAAACACAAACGCTTTGATCTGGGCTTAGAA
GATGTGTTAATTCCTCACGTAGATGCGGGCAAAGGGGCTAAAGACCCCGGAGTCTTCCTGATTC
ATGGACCCGACGAACACAGACACAGGGAAGAAGAAGAGCGTCTGAGAAATAAGATTAGAGCTGA
TCATGAGAAAGCCCTGGAAGAAGCAAAAGAAAAATTAAGAAAGTCAAGAGAGGAAATCCGTGCA
GAAATTCAGACAGAGAAAAATAAAGTAGCCCAAGCAATGAAGACAAAAGAGACCAGGGTACTGC
CACCTGTCCCTGTCCCACAGCGTGTAGGGGTCAGTGGTGGGGACCCAGAAGACGCGGAGATCAG
GAAGAAAAGAGACAAAATTAAAGAGATGATGAAACATGCCTGGGATAATTACAGAACATACGGA
TGGGGCCATAATGAGCTCAGACCTATTGCAAGGAAAGGGCATTCCACTAACATATTCGGAAGCT
CACAGATGGGGGCCACCATAGTGGATGCTTTGGATACCCTTTATATCATGGGGCTTCATGATGA
ATTCATGGATGGGCAAAGATGGATTGAAGACAACCTTGATTTCAGTGTGAACTCGGAAGTGTCT
GTGTTTGAAGTTAACATTCGCTTTATTGGAGGGCTCCTTGCAGCATATTACCTGTCAGGAGAGG
AAATTTTCAAGACTAAAGCAGTGCAGTTGGCTGAGAAGCTCCTTCCTGCCTTTAACACTCCTAC
TGGGATTCCTTGGGCAATGGTGAACCTGAAAAGTGGAGTAGGTCGGAACTGGGGCTGGGCATCT
GCAGGCAGCAGCATCCTGGCTGAATTTGGCACCCTGCACATGGAGTTCGTGCACCTCAGCTACT
TGACTGGTGACCTGACTTACTATAATAAGGTCATGCACATCCGGAAACTACTACAGAAAATGGA
ACGCCCAAATGGTCTTTATCCAAATTATTTAAACCCGAGGACAGGGCGCTGGGGTCAGTATCAC
ACATCAGTTGGTGGCCTAGGTGACAGTTTTTATGAATACTTACTAAAAGCATGGCTGATGTCAG
ATAAAACAGACCACGAGGCAAGAAGGATGTACGACGACGCTGTTGAGGCTATAGAGAAACATCT
TATTAAGAAGTCCCGAGGAGGTCTAGTCTTTATTGGAGAATGGAAAAATGGACACTTGGAAAGG
AAGATGGGTCATTTGGCCTGCTTTGCTGGGGGAATGTTTGCACTTGGAGCGGATGGTTCCAGAA
AGGATAAAGCTGGCCACTATTTAGAACTAGGGGCAGAAATTGCACGAACATGCCATGAGTCATA
TGACAGAACTGCATTAAAACTAGGTCCTGAGTCATTCAAGTTTGATGGTGCAGTGGAAGCAGTG
GCTGTGCGGCAAGCTGAGAAGTATTACATCCTTCGTCCGGAAGTGATCGAAACCTATTGGTATC
TATGGCGATTCACCCACGACCCAAGATACAGGCAGTGGGGCTGGGAAGCCGCATTGGCTATTGA
GAAGTCCTGCCGAGTCAGTGGTGGGTTTTCTGGTGTCAAGGATGTCTACTCCCCGACTCCTGCG
CACGACGACGTGCAGCAGAGCTTTTTTCTTGCCGAGACGTTAAAATACTTGTACCTGCTGTTCT
CTGGCGATGACCTCCTACCTTTAGACCACTGGGTGTTTAATACAGAGGCTCATCCTCTGCCGGT
GTTGCGTTTAGCCAACACCACTCTTTCAGGTAACCCTGCTGTTCGATGAGCACAGCTGCAGAAG
GACCATTCTTACCTGTGTTTTGTTTACATGGACCACTACAGAAATTGTCTGGAGAGGCGGCTTT
TGAAAACCTGGACCTTTACATCAATATGCCGGATGGAACTCTTCCCTGCAAGACTTTTCACTTG
TAGATATATCAACTTTGAAATTATTCCATTTTATACCTGACCAAAACATGTTCTGGTACACGTA
GGACAGAGACCTGATGTGTTTTGATTCTTAATGAGATGGCCACATGAGAAACAATGTCTTATTC
TATACTGTCAGTGCAAATCAAGAACATAGAGCACCTTACAGGAGTTAGAGATGGCTTTTGAACC
AATTATACATTTGTTTCCTCCCACAGTGGAGCAGCTTTCAAATAAAATATAACATATTGTGTAG
CCCCTTTCCTCCATTTTAATAATGGAACAAACGGAATGACCAGGAACAGAGGAACAGTGTAACT
ACATTGTAGCAAGAAGACTTGGGAAAGCAACAGATACTGTCCCTGTCTGAATTTTCAAGCTCCT
CATTGGATTTTTACCAGACTGGCAACCATTTTATTCCCAACCTAGTCATTGAAATCTGTTTAGA
TTTAGTTTTTCTCTGAGGGGCATGATCTCATGAAGAATACTTTTCAAGTCTTTGTCTCCGTATG
ATATGCTGAACCTGGTATTTATCATAACTGCTGCTTATGAGCCCAAGTGTGGGAGTGTGCATGT
AGCTCACGCTAGCGTTGGGAGCATGGCGGAAGGTGGGGAAGTGCCAGATTGTTGCCTGAAACCT
ATTTGAGAGAAATCCTTGATTTGTTGGTAGGAAATTATCTTCTGAACCAACAACTGAATCAAGC
AAACATTTTCTGCTTTAATCTCACAACACAGTTAATAGAGTCATTTACCTTCCACGTCATGTGG
CTTGGCAAAATCGACTACACTGTCAAGCAGCTCTGTATTTGCTAGAACAAGCCTGATCGCTTAC
AACTTCCTAAAGCAAAGGCAAAAGTCTGCAGTGTCCCTCGAGCAGGGTCAGGCGCTCTACTTGT
TACCTCACAGGTGTGAGCTGCTCACAAAGAGTCCATGTTTTTAAGTTTCTCCAAGATATTATAC
ATCCAAAGAATTACTAGAATAGCTTCAAAGTAATCTTCAGAGGCAAATGTGTGATGTAAGAATC
ATACTCACTAAAACTGACATAAACCT

hide sequence

RefSeq Acc Id:

XM_039102060 ⟹ XP_038957988

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	187,947,484 - 188,095,533 (-)	NCBI

RefSeq Acc Id:

XM_039102061 ⟹ XP_038957989

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	187,947,484 - 188,053,130 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099922	(Get FASTA)	NCBI Sequence Viewer
	XP_038957988	(Get FASTA)	NCBI Sequence Viewer
	XP_038957989	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL85534	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001099922 ⟸ NM_001106452

- UniProtKB:

D3ZR49 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHK
RFDLGLEDVLIPHVDAGKGAKDPGVFLIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRK
SREEIRAEIQTEKNKVAQAMKTKETRVLPPVPVPQRVGVSGGDPEDAEIRKKRDKIKEMMKHAW
DNYRTYGWGHNELRPIARKGHSTNIFGSSQMGATIVDALDTLYIMGLHDEFMDGQRWIEDNLDF
SVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKTKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVG
RNWGWASAGSSILAEFGTLHMEFVHLSYLTGDLTYYNKVMHIRKLLQKMERPNGLYPNYLNPRT
GRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARRMYDDAVEAIEKHLIKKSRGGLVFIGEW
KNGHLERKMGHLACFAGGMFALGADGSRKDKAGHYLELGAEIARTCHESYDRTALKLGPESFKF
DGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKSCRVSGGFSGVKD
VYSPTPAHDDVQQSFFLAETLKYLYLLFSGDDLLPLDHWVFNTEAHPLPVLRLANTTLSGNPAV
R

hide sequence

RefSeq Acc Id:

ENSRNOP00000060243 ⟸ ENSRNOT00000067000

RefSeq Acc Id:	XP_038957988 ⟸ XM_039102060
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038957989 ⟸ XM_039102061
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSRNOP00000095157 ⟸ ENSRNOT00000105480

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZR49-F1-model_v2	AlphaFold	D3ZR49	1-640	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309767	AgrOrtholog
BioCyc Gene	G2FUF-51876	BioCyc
BioCyc Pathway	PWY-7919 [protein N-glycosylation processing phase (plants and animals)]	BioCyc
Ensembl Genes	ENSRNOG00000015226	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000060243	ENTREZGENE
	ENSRNOP00000060243.4	UniProtKB/TrEMBL
	ENSRNOP00000095157.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000067000	ENTREZGENE
	ENSRNOT00000067000.4	UniProtKB/TrEMBL
	ENSRNOT00000105480.1	UniProtKB/TrEMBL
Gene3D-CATH	1.50.10.10	UniProtKB/TrEMBL
InterPro	6hp_glycosidase-like_sf	UniProtKB/TrEMBL
	Glyco_hydro_47	UniProtKB/TrEMBL
	Seven-hairpin_glycosidases	UniProtKB/TrEMBL
KEGG Report	rno:295319	UniProtKB/TrEMBL
NCBI Gene	295319	ENTREZGENE
PANTHER	MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IB	UniProtKB/TrEMBL
	MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED	UniProtKB/TrEMBL
Pfam	Glyco_hydro_47	UniProtKB/TrEMBL
PhenoGen	Man1a2	PhenoGen
PRINTS	GLYHDRLASE47	UniProtKB/TrEMBL
Superfamily-SCOP	Glyco_hydro_47	UniProtKB/TrEMBL
UniProt	A0A8I6ANZ7_RAT	UniProtKB/TrEMBL
	D3ZR49	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Man1a2	mannosidase, alpha, class 1A, member 2	Man1a2_predicted	mannosidase, alpha, class 1A, member 2 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Man1a2_predicted	mannosidase, alpha, class 1A, member 2 (predicted)	Man1b_predicted	mannosidase 1, beta (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-12	Man1b_predicted	mannosidase 1, beta (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)