Spsb1 (splA/ryanodine receptor domain and SOCS box containing 1) - Rat Genome Database

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Gene: Spsb1 (splA/ryanodine receptor domain and SOCS box containing 1) Rattus norvegicus
Analyze
Symbol: Spsb1
Name: splA/ryanodine receptor domain and SOCS box containing 1
RGD ID: 1309319
Description: Predicted to enable ubiquitin ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to be located in cytosol. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human SPSB1 (splA/ryanodine receptor domain and SOCS box containing 1); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC313722; RGD1309319; similar to SPRY domain-containing SOCS box protein SSB-1; SPRY domain-containing SOCS box protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85165,641,255 - 165,701,482 (-)NCBIGRCr8
mRatBN7.25160,358,292 - 160,418,541 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5160,358,308 - 160,418,468 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5163,076,400 - 163,087,774 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05164,898,077 - 164,909,555 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05164,854,450 - 164,865,926 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05166,913,734 - 166,978,534 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5166,913,735 - 166,926,636 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05170,555,623 - 170,619,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45167,014,271 - 167,025,579 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15167,022,865 - 167,035,827 (-)NCBI
Celera5158,623,982 - 158,634,651 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxyethyl methacrylate  (ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
butan-1-ol  (ISO)
C60 fullerene  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chloroacetaldehyde  (ISO)
chloroprene  (ISO)
chlorpromazine  (EXP)
choline  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (EXP,ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (EXP,ISO)
diethylstilbestrol  (ISO)
dimethylarsinous acid  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
diuron  (EXP)
doramapimod  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
fenofibrate  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
glyphosate  (ISO)
ifosfamide  (ISO)
isoprenaline  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
lead diacetate  (ISO)
Licochalcone B  (ISO)
mercury dichloride  (EXP)
metformin  (EXP)
methapyrilene  (ISO)
methoxychlor  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sotorasib  (ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trametinib  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:19028597   PMID:21199876  


Genomics

Comparative Map Data
Spsb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85165,641,255 - 165,701,482 (-)NCBIGRCr8
mRatBN7.25160,358,292 - 160,418,541 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5160,358,308 - 160,418,468 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5163,076,400 - 163,087,774 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05164,898,077 - 164,909,555 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05164,854,450 - 164,865,926 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05166,913,734 - 166,978,534 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5166,913,735 - 166,926,636 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05170,555,623 - 170,619,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45167,014,271 - 167,025,579 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15167,022,865 - 167,035,827 (-)NCBI
Celera5158,623,982 - 158,634,651 (-)NCBICelera
Cytogenetic Map5q36NCBI
SPSB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819,292,894 - 9,369,532 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl19,292,894 - 9,369,532 (+)EnsemblGRCh38hg38GRCh38
GRCh3719,352,953 - 9,429,591 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619,275,571 - 9,352,178 (+)NCBINCBI36Build 36hg18NCBI36
Celera18,462,669 - 8,539,361 (+)NCBICelera
Cytogenetic Map1p36.22NCBI
HuRef18,547,970 - 8,579,365 (+)NCBIHuRef
CHM1_119,388,399 - 9,419,828 (+)NCBICHM1_1
T2T-CHM13v2.018,827,769 - 8,904,391 (+)NCBIT2T-CHM13v2.0
Spsb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394149,980,740 - 150,039,494 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4149,980,740 - 150,039,500 (-)EnsemblGRCm39 Ensembl
GRCm384149,896,283 - 149,955,006 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4149,896,283 - 149,955,043 (-)EnsemblGRCm38mm10GRCm38
MGSCv374149,270,392 - 149,329,115 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364148,740,083 - 148,798,806 (-)NCBIMGSCv36mm8
Celera4152,167,650 - 152,226,371 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map480.46NCBI
Spsb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554864,022,306 - 4,115,077 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554864,022,307 - 4,061,111 (-)NCBIChiLan1.0ChiLan1.0
SPSB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21218,856,729 - 218,935,323 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11217,504,077 - 217,580,356 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v018,053,596 - 8,132,143 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.119,349,825 - 9,363,624 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl19,349,825 - 9,363,624 (+)Ensemblpanpan1.1panPan2
SPSB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1562,640,420 - 62,669,606 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl562,639,629 - 62,667,790 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha562,616,269 - 62,685,333 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0562,825,418 - 62,894,575 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl562,825,374 - 62,894,572 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1562,824,606 - 62,892,430 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0562,687,237 - 62,756,451 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0563,091,729 - 63,160,856 (+)NCBIUU_Cfam_GSD_1.0
Spsb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505832,918,113 - 32,970,426 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366233,427,761 - 3,455,670 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366233,448,787 - 3,455,670 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPSB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl669,720,806 - 69,791,119 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1669,720,538 - 69,789,566 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SPSB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120122,398,856 - 122,474,175 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20122,396,931 - 122,474,190 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605426,413,485 - 26,489,158 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spsb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248182,964,984 - 2,983,433 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248182,965,222 - 3,014,544 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Spsb1
263 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:142
Count of miRNA genes:104
Interacting mature miRNAs:111
Transcripts:ENSRNOT00000023287
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5151006154161165494Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat

Markers in Region
BE114497  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25160,399,752 - 160,399,902 (+)MAPPERmRatBN7.2
Rnor_6.05166,959,629 - 166,959,778NCBIRnor6.0
Rnor_5.05170,601,037 - 170,601,186UniSTSRnor5.0
RGSC_v3.45167,053,914 - 167,054,063UniSTSRGSC3.4
Celera5158,663,127 - 158,663,276UniSTS
RH 3.4 Map51115.0UniSTS
Cytogenetic Map5q36UniSTS
RH128720  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25160,358,459 - 160,358,664 (+)MAPPERmRatBN7.2
Rnor_6.05166,913,902 - 166,914,106NCBIRnor6.0
Rnor_5.05170,555,791 - 170,555,995UniSTSRnor5.0
RGSC_v3.45167,012,843 - 167,013,047UniSTSRGSC3.4
Celera5158,622,554 - 158,622,758UniSTS
RH 3.4 Map51119.2UniSTS
Cytogenetic Map5q36UniSTS
RH129227  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25160,358,949 - 160,359,157 (+)MAPPERmRatBN7.2
Rnor_6.05166,914,392 - 166,914,599NCBIRnor6.0
Rnor_5.05170,556,281 - 170,556,488UniSTSRnor5.0
RGSC_v3.45167,013,333 - 167,013,540UniSTSRGSC3.4
Celera5158,623,044 - 158,623,251UniSTS
RH 3.4 Map51121.3UniSTS
Cytogenetic Map5q36UniSTS
BE106389  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25160,359,906 - 160,360,100 (+)MAPPERmRatBN7.2
Rnor_6.05166,915,349 - 166,915,542NCBIRnor6.0
Rnor_5.05170,557,238 - 170,557,431UniSTSRnor5.0
RGSC_v3.45167,014,290 - 167,014,483UniSTSRGSC3.4
Celera5158,624,001 - 158,624,194UniSTS
RH 3.4 Map51115.5UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 9 2 25 5 39 8
Low 2 43 44 37 17 37 8 11 49 30 2 3 8
Below cutoff 4 4 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000023287   ⟹   ENSRNOP00000023287
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5166,915,330 - 166,926,636 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085251   ⟹   ENSRNOP00000074486
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5160,358,308 - 160,418,468 (-)Ensembl
Rnor_6.0 Ensembl5166,913,735 - 166,924,136 (-)Ensembl
RefSeq Acc Id: NM_001107994   ⟹   NP_001101464
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85165,642,851 - 165,654,225 (-)NCBI
mRatBN7.25160,359,888 - 160,371,262 (-)NCBI
Rnor_6.05166,915,330 - 166,926,636 (-)NCBI
Rnor_5.05170,555,623 - 170,619,867 (-)NCBI
RGSC_v3.45167,014,271 - 167,025,579 (-)RGD
Celera5158,623,982 - 158,634,651 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239462   ⟹   XP_006239524
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85165,641,255 - 165,701,482 (-)NCBI
mRatBN7.25160,358,292 - 160,418,541 (-)NCBI
Rnor_6.05166,913,734 - 166,978,534 (-)NCBI
Rnor_5.05170,555,623 - 170,619,867 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008764258   ⟹   XP_008762480
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85165,641,255 - 165,654,297 (-)NCBI
mRatBN7.25160,358,292 - 160,371,615 (-)NCBI
Rnor_6.05166,913,734 - 166,926,702 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001101464 (Get FASTA)   NCBI Sequence Viewer  
  XP_006239524 (Get FASTA)   NCBI Sequence Viewer  
  XP_008762480 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58604 (Get FASTA)   NCBI Sequence Viewer  
  EDL81174 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000074486
  ENSRNOP00000074486.1
Reference Protein Sequences
RefSeq Acc Id: NP_001101464   ⟸   NM_001107994
- UniProtKB: B0BMX8 (UniProtKB/TrEMBL),   A6IUC3 (UniProtKB/TrEMBL),   A0A0G2K863 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239524   ⟸   XM_006239462
- Peptide Label: isoform X1
- UniProtKB: B0BMX8 (UniProtKB/TrEMBL),   A6IUC3 (UniProtKB/TrEMBL),   A0A0G2K863 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762480   ⟸   XM_008764258
- Peptide Label: isoform X1
- UniProtKB: B0BMX8 (UniProtKB/TrEMBL),   A6IUC3 (UniProtKB/TrEMBL),   A0A0G2K863 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074486   ⟸   ENSRNOT00000085251
RefSeq Acc Id: ENSRNOP00000023287   ⟸   ENSRNOT00000023287
Protein Domains
B30.2/SPRY   SOCS box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0BMX8-F1-model_v2 AlphaFold B0BMX8 1-273 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694277
Promoter ID:EPDNEW_R4802
Type:initiation region
Name:Spsb1_1
Description:splA/ryanodine receptor domain and SOCS box containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05166,926,631 - 166,926,691EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309319 AgrOrtholog
BioCyc Gene G2FUF-39097 BioCyc
Ensembl Genes ENSRNOG00000017212 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000085251.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  SOCS box UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7133644 IMAGE-MGC_LOAD
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  ConA-like_dom UniProtKB/TrEMBL
  SOCS_C UniProtKB/TrEMBL
  SPRY_rcpt UniProtKB/TrEMBL
KEGG Report rno:313722 UniProtKB/TrEMBL
MGC_CLONE MGC:187459 IMAGE-MGC_LOAD
NCBI Gene 313722 ENTREZGENE
PANTHER SPRY DOMAIN CONTAINING SOCS BOX PROTEIN UniProtKB/TrEMBL
  SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 1 UniProtKB/TrEMBL
Pfam SOCS_box UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
PhenoGen Spsb1 PhenoGen
PROSITE B302_SPRY UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017212 RatGTEx
SMART SOCS_box UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP ConA_like_lec_gl UniProtKB/TrEMBL
UniProt A0A0G2K863 ENTREZGENE, UniProtKB/TrEMBL
  A6IUC3 ENTREZGENE, UniProtKB/TrEMBL
  B0BMX8 ENTREZGENE
UniProt Secondary B0BMX8 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Spsb1  splA/ryanodine receptor domain and SOCS box containing 1   Spsb1_predicted  splA/ryanodine receptor domain and SOCS box containing 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Spsb1_predicted  splA/ryanodine receptor domain and SOCS box containing 1 (predicted)  RGD1309319_predicted  similar to SPRY domain-containing SOCS box protein SSB-1 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1309319_predicted  similar to SPRY domain-containing SOCS box protein SSB-1 (predicted)  LOC313722_predicted  similar to SPRY domain-containing SOCS box protein SSB-1 (predicted)  Symbol and Name status set to approved 1331353 APPROVED
2005-01-20 RGD1309319_predicted  similar to SPRY domain-containing SOCS box protein SSB-1 (predicted)  LOC313722_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313722_predicted  similar to SPRY domain-containing SOCS box protein SSB-1 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL