Btg4 (BTG anti-proliferation factor 4)

Gene: Btg4 (BTG anti-proliferation factor 4) Rattus norvegicus

Analyze

Symbol:

Btg4

Name:

BTG anti-proliferation factor 4

RGD ID:

1308809

Description:

Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in negative regulation of cell population proliferation and negative regulation of mitotic cell cycle. Predicted to act upstream of or within maternal-to-zygotic transition of gene expression. Predicted to be active in cytoplasm and nucleus. Orthologous to human BTG4 (BTG anti-proliferation factor 4); PARTICIPATES IN RNA degradation pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

B-cell translocation gene 4; BTG family member 4; LOC315650; SCIR-27

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BTG4 (BTG anti-proliferation factor 4)	HGNC	Ensembl, Inparanoid, NCBI, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):	Btg4 (BTG anti-proliferation factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Btg4 (BTG anti-proliferation factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BTG4 (BTG anti-proliferation factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LOC102153351 (uncharacterized LOC102153351)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Btg4 (BTG anti-proliferation factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BTG4 (BTG anti-proliferation factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BTG4 (BTG anti-proliferation factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Btg4 (BTG anti-proliferation factor 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	RTN3 (reticulon 3)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	BTG4 (BTG anti-proliferation factor 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Btg4 (BTG anti-proliferation factor 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	btg4 (B-cell translocation gene 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	btg4	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	60,307,090 - 60,322,167 (+)	NCBI		GRCr8
mRatBN7.2	8	51,410,774 - 51,425,802 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	51,422,061 - 51,425,796 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	56,969,662 - 56,973,419 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	55,248,589 - 55,252,346 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	53,112,851 - 53,116,609 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	55,408,917 - 55,508,100 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	55,504,359 - 55,508,259 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	54,089,729 - 54,104,457 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	54,434,387 - 54,438,128 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	54,453,440 - 54,457,179 (+)	NCBI
Celera	8	50,968,431 - 50,972,180 (+)	NCBI		Celera
Cytogenetic Map	8	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

ataxia telangiectasia (ISO)

BH4-deficient hyperphenylalaninemia A (ISO)

Carney-Stratakis syndrome (ISO)

Chromosome 11, Partial Trisomy 11q (ISO)

genetic disease (ISO)

intellectual disability (ISO)

Oocyte/Zygote/Embryo Maturation Arrest 8 (ISO)

Pyruvate Dehydrogenase E2 Deficiency (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

copper atom (EXP)

copper(0) (EXP)

Cuprizon (EXP)

fonofos (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

graphite (EXP)

methapyrilene (ISO)

ozone (ISO)

paracetamol (ISO)

parathion (ISO)

pyrogallol (ISO)

sodium arsenite (ISO)

terbufos (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

maternal-to-zygotic transition of gene expression (ISO)

negative regulation of cell population proliferation (IBA)

negative regulation of mitotic cell cycle (IBA,ISO)

Cellular Component

cytoplasm (IBA)

nucleus (IBA)

Molecular Function

mRNA 3'-UTR binding (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA degradation pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:10995567

Genomics

Comparative Map Data

Btg4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	60,307,090 - 60,322,167 (+)	NCBI		GRCr8
mRatBN7.2	8	51,410,774 - 51,425,802 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	51,422,061 - 51,425,796 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	56,969,662 - 56,973,419 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	55,248,589 - 55,252,346 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	53,112,851 - 53,116,609 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	55,408,917 - 55,508,100 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	55,504,359 - 55,508,259 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	54,089,729 - 54,104,457 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	54,434,387 - 54,438,128 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	54,453,440 - 54,457,179 (+)	NCBI
Celera	8	50,968,431 - 50,972,180 (+)	NCBI		Celera
Cytogenetic Map	8	q23	NCBI

BTG4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	111,383,826 - 111,514,725 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	111,467,526 - 111,514,367 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	111,338,251 - 111,385,450 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	110,843,465 - 110,888,274 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	110,843,467 - 110,888,274	NCBI
Celera	11	108,491,434 - 108,536,253 (-)	NCBI		Celera
Cytogenetic Map	11	q23.1	NCBI
HuRef	11	107,262,780 - 107,307,277 (-)	NCBI		HuRef
CHM1_1	11	111,221,343 - 111,266,174 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	111,393,991 - 111,524,873 (-)	NCBI		T2T-CHM13v2.0

Btg4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	51,013,486 - 51,031,224 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	50,972,201 - 51,031,175 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	51,102,147 - 51,119,924 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	51,060,901 - 51,119,875 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	50,924,106 - 50,927,805 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	50,868,231 - 50,871,930 (+)	NCBI		MGSCv36	mm8
Celera	9	48,402,491 - 48,406,190 (+)	NCBI		Celera
Cytogenetic Map	9	A5.3	NCBI
cM Map	9	27.84	NCBI

Btg4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	13,183,524 - 13,247,882 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	13,137,273 - 13,250,261 (-)	NCBI	ChiLan1.0	ChiLan1.0

BTG4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	112,202,213 - 112,258,119 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	113,294,277 - 113,350,171 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	106,374,407 - 106,394,341 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	110,219,490 - 110,236,589 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	110,219,490 - 110,236,589 (-)	Ensembl	panpan1.1		panPan2

LOC102153351
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	21,480,138 - 21,556,544 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	21,426,136 - 21,463,020 (+)	NCBI		Dog10K_Boxer_Tasha

Btg4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	93,779,003 - 93,783,009 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936612	2,922,611 - 2,926,346 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936612	2,922,611 - 2,959,253 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BTG4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	39,237,461 - 39,301,588 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	39,253,116 - 39,281,327 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	44,183,288 - 44,194,432 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BTG4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	102,841,089 - 102,846,723 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	102,828,923 - 102,832,544 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
ChlSab1.1 Ensembl	1	102,828,923 - 102,832,544 (-)	NCBI	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	23,126,818 - 23,145,203 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Btg4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624784	6,583,478 - 6,611,475 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624784	6,582,560 - 6,624,212 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Btg4
57 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	265
Count of miRNA genes:	175
Interacting mature miRNAs:	203
Transcripts:	ENSRNOT00000059086
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2301416	Bp315	Blood pressure QTL 315		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	7670578	52670578	Rat
1354595	Despr4	Despair related QTL 4	2.16	0.0036	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	8	7688955	52688955	Rat
1354627	Despr14	Despair related QTL 14		0.0056	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	7688955	52688955	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	8462195	110921472	Rat
2317030	Wbc5	White blood cell count QTL 5	3.21	0.005	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	8	8736635	53736635	Rat
2317051	Aia18	Adjuvant induced arthritis QTL 18	2.42		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	8	8736635	53736635	Rat
1598824	Memor4	Memory QTL 4	2.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	8	9712220	53356647	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10378157	112202585	Rat
1558646	Swd5	Spike wave discharge measurement QTL 5	3.45	0.00036	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	8	14906751	59906751	Rat
61373	Mcs4	Mammary carcinoma susceptibility QTL 4	1.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	8	16290444	61290444	Rat
631271	Lecl1	Lens clarity QTL 1		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	8	18984168	84531599	Rat
731182	Uae24	Urinary albumin excretion QTL 24	6.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	19331152	93965294	Rat
631842	Inf1	Infertility severity QTL 1	4.1	0.001	seminal gland mass (VT:0010524)	seminal vesicle wet weight (CMO:0001603)	8	22662330	67662330	Rat
2303564	Gluco43	Glucose level QTL 43	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	26130187	71130187	Rat
2303572	Insul13	Insulin level QTL 13	2		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	8	26130187	71130187	Rat
631648	Stl5	Serum triglyceride level QTL 5	4	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	27205715	54998217	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	27205715	99103503	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	27205715	99103503	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	27205715	99103503	Rat
1331804	Cm30	Cardiac mass QTL 30	3.77443		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	8	28242912	53961020	Rat
1300146	Rf17	Renal function QTL 17	2.9		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	8	28242912	73242912	Rat
8662823	Vetf5	Vascular elastic tissue fragility QTL 5	1.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	8	28242912	99525068	Rat
724514	Uae15	Urinary albumin excretion QTL 15	2.9		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	29502665	70386295	Rat
1549908	Neudeg1	Neurodegradation QTL 1	5.5	0	nervous system integrity trait (VT:0010566)	logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)	8	30188867	94457446	Rat
1331744	Bp217	Blood pressure QTL 217	3.398		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	58482492	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	61290444	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	61290444	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	30848154	61290444	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	30848154	61290444	Rat
11556286	Cm81	Cardiac mass QTL 81		0.01	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	30848154	61290444	Rat
1359033	Bp273	Blood pressure QTL 273			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	61290444	Rat
2313046	Bss78	Bone structure and strength QTL 78	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	8	30848154	82460899	Rat
2313057	Bss76	Bone structure and strength QTL 76	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	8	30848154	82460899	Rat
2313067	Bss77	Bone structure and strength QTL 77	3.1	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	8	30848154	82460899	Rat
2313088	Bss75	Bone structure and strength QTL 75	3.1	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	8	30848154	82460899	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	30848154	101699754	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	30848154	101699754	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	30848154	101699754	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	30848259	105647037	Rat
1298065	Scl16	Serum cholesterol level QTL 16	3.8		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	30856404	75856404	Rat
1582222	Epfw2	Epididymal fat weight QTL 2	3.2	0.0005	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	8	31737729	76737729	Rat
61358	Bp39	Blood pressure QTL 39	2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	35551938	80551938	Rat
61464	Niddm11	Non-insulin dependent diabetes mellitus QTL 11	3.1	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	35582032	80582032	Rat
1331838	Niddm61	Non-insulin dependent diabetes mellitus QTL 61	3.53	0.0004	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	36469535	99083736	Rat
737824	Hcar10	Hepatocarcinoma resistance QTL 10	2.9		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	8	40713066	82925667	Rat
1358906	Bp253	Blood pressure QTL 253	4	0.0004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	40713066	93965294	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	40952565	123900184	Rat
1331769	Rf39	Renal function QTL 39	3.871		urine output (VT:0003620)	timed urine volume (CMO:0000260)	8	41866876	75097878	Rat
1298079	Activ2	Activity QTL 2	9.5	0.000001	voluntary movement trait (VT:0003491)	rearing measurement (CMO:0001515)	8	41866876	86866876	Rat
631216	Stl9	Serum triglyceride level QTL 9	4.71	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	8	41867010	70386132	Rat
70161	Bp62	Blood pressure QTL 62	2.9	0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	42692684	90165460	Rat
12879882	Am8	Aortic mass QTL 8		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	43296169	98968765	Rat
12879878	Bw183	Body weight QTL 183		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	43296169	98968765	Rat
12879879	Cm99	Cardiac mass QTL 99		0.001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	43296169	98968765	Rat
12879880	Cm100	Cardiac mass QTL 100		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	43296169	98968765	Rat
12879881	Cm101	Cardiac mass QTL 101		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	8	43296169	98968765	Rat
12879883	Kidm65	Kidney mass QTL 65		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	43296169	98968765	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	46531639	119088626	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	8	46531639	119088626	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	8	46531639	119088626	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	46531639	119088626	Rat
1331837	Bw23	Body weight QTL 23	4.19	0.00007	body mass (VT:0001259)	body weight (CMO:0000012)	8	46531722	99083736	Rat
2303570	Gluco48	Glucose level QTL 48	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	49805831	94805831	Rat
2313086	Bss60	Bone structure and strength QTL 60	4.1	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	8	50095249	82460899	Rat
4889938	Bss89	Bone structure and strength QTL 89	3.8		tibia size trait (VT:0100001)	tibia cortical bone volume (CMO:0001725)	8	50095249	82460899	Rat
5684973	Bss100	Bone structure and strength QTL 100	4.7		tibia area (VT:1000281)	tibia area measurement (CMO:0001382)	8	50095249	82460899	Rat
1358912	Bw51	Body weight QTL 51	2.95		body mass (VT:0001259)	body weight (CMO:0000012)	8	51351728	107062046	Rat

Markers in Region

RH127262

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	51,425,391 - 51,425,663 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	55,507,690 - 55,507,961	NCBI	Rnor6.0
Rnor_5.0	8	54,104,047 - 54,104,318	UniSTS	Rnor5.0
RGSC_v3.4	8	54,437,718 - 54,437,989	UniSTS	RGSC3.4
Celera	8	50,971,770 - 50,972,041	UniSTS
Cytogenetic Map	8	q24	UniSTS

BE119988

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	51,425,575 - 51,425,727 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	55,507,874 - 55,508,025	NCBI	Rnor6.0
Rnor_5.0	8	54,104,231 - 54,104,382	UniSTS	Rnor5.0
RGSC_v3.4	8	54,437,902 - 54,438,053	UniSTS	RGSC3.4
Celera	8	50,971,954 - 50,972,105	UniSTS
RH 3.4 Map	8	555.8	UniSTS
Cytogenetic Map	8	q24	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	nervous system	renal system	reproductive system	respiratory system
High
Medium							1
Low					15		12
Below cutoff	1	6	1	1	55	8	18	2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013176	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001401094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006243035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006243036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595628	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595629	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595630	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595631	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595632	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595634	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595635	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595638	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY960132	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC088755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000059086 ⟹ ENSRNOP00000055863

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	51,422,061 - 51,425,796 (+)	Ensembl
Rnor_6.0 Ensembl	8	55,504,359 - 55,508,094 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000088320 ⟹ ENSRNOP00000072007

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	51,422,061 - 51,425,780 (+)	Ensembl
Rnor_6.0 Ensembl	8	55,504,857 - 55,508,259 (+)	Ensembl

RefSeq Acc Id:

NM_001013176 ⟹ NP_001013194

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	60,318,412 - 60,322,167 (+)	NCBI
mRatBN7.2	8	51,422,047 - 51,425,802 (+)	NCBI
Rnor_6.0	8	55,504,359 - 55,508,100 (+)	NCBI
Rnor_5.0	8	54,089,729 - 54,104,457 (+)	NCBI
RGSC_v3.4	8	54,434,387 - 54,438,128 (+)	RGD
Celera	8	50,968,431 - 50,972,180 (+)	RGD

Sequence:

show sequence

GTTGGCAGCAAGTAATGTAGCTGGTACTCTAACCTTGGACCACTTTTTGTAGAGACCAGAGAAA
TCTTGATAGCAAGGGTAATGCATTTTTATTAATCTTTAACTGTGCGGTTTTGTAAGTCGCAGTT
TTCCAACAGTGGTCCTCTGAAGCCTGGATATTTGACTCTTTGTCCCTACCCAGACTGCTTTGGA
ATCATGAGAGATGAAATTGCAACAGCAGTTTTTTTTGTCACAAGACTGGCGAAAAAGCACGAGA
AACTGAGTACCCAACAGATAGAAACCTTCGCGCTGAAGCTGATGACTGTCTTGTTTGAAAAGTA
CAGAGGTCACTGGCACCCTGACTGCCCTTCTAAGGGGCAGGCTTTTAGGTGTATCAGGATAAAC
AACAACGAGAATAAAGACCCTGTTTTAGAAAGGGCTTGTTCTGAGAGTAATGTGAATTTTTTTC
ATCTGGGACTTCCAAAGGAGATGACCATATGGGTCGATCCCTTTGAGGTGTGCTGTAGGTTGAA
AACTTCAAACCGTCCTTCCAGCCGTGGCTCTGCCTCCCCCGCAGAAAGCATTTGGCAGATGGTC
ATGGCTGCCTCCTGGGGGCTGCTTACCACCCAATGCCCAAGAACTCTAAGTGGTGCAGGCATGC
TGGGCATCGGGTGGACAGGTATCACTGGGTCAACACACAGTTGATCAGTGGTCAGACAGCACCA
GGCGAGCTTGGAGAAGAGGCCTTGTCTTCCCGAAAGCAAAAATGAGGGTAGAGCTAAGAAATAC
TCCCAGTAAAAAAAACACAACAAACAAAACAAACGGCTGCTTCGGGGATGTGAGCATACAAGGC
CACCCTTGCACACAGAACTGCTTCAGGGATGTGAGCATACAAGGCCATCCTTGCACACAGATTG
CCACCTGACTTTTAGCTACTTTTAATTCTCATTTTACTTTATGTAACGTTTTATGAACACTAGT
GAATATATGTGCCAAGTAAAGTGATAGAATGAAAATATTGCCTGTGATAAAATAAAATGAATTT
TAGGAAGAAAGACTTGAAATAAATACTCTTGTGTTTTTAACAAAAAAAATAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001401094 ⟹ NP_001388023

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	60,318,412 - 60,322,167 (+)	NCBI
mRatBN7.2	8	51,422,047 - 51,425,802 (+)	NCBI

RefSeq Acc Id:

XM_006243035 ⟹ XP_006243097

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	60,307,090 - 60,322,167 (+)	NCBI
mRatBN7.2	8	51,410,774 - 51,425,802 (+)	NCBI
Rnor_6.0	8	55,492,794 - 55,508,100 (+)	NCBI
Rnor_5.0	8	54,089,729 - 54,104,457 (+)	NCBI

Sequence:

show sequence

CCCCGCAGTCCCCGGAGACCCTCCCGCTCCGCCCCAACCCCAGGGCATCGGGCCGGAGTCCTGC
TCTCCCTCACGCCGGGTCTGACCCGTCTCCGTTAACTTCTCCACGGCTTCCAGACCCAACTCTA
GAGCCGGTTCGGTCCAGCCCGCGCGCCCTGCAGCTCCTACTGGCCGAGTGACCGTGGCTCTGCG
ACCAACCGCCCTTGGAACCCCGAGGCCGAGGGGGCGGGGCGAGTGGGGGAGGGGCGGCAGAAGC
TACCAGAAGGGGCAATGGGCGGGCTCCTGCAGAGCCTCCTGGGAAGGGGCCCGGGAGATGAAGA
GACAGATTCTTGAGAAGTTTGTCTTCATACTGTACTTAATACTACATTGAAGAAAGAAGCGCAA
AGACCTACATCCATCTCTCCTTCTTTATTGCCCAAGGAGCCCCAAGCCTCCTCACTGTTCATGC
CCATCCTCAGAAACAGTTTCCCAGGCATCTCATCTCGAGCCTTCCTGCATTAGCAGGCCTGGGC
ACTCTTACCTGCAGCACTGCCCTTGCCAATACCCGAGTTCTTTCTTAGGACTGACTACCTCTTA
CAGGGCCATGCAGTGAGATTAAGAAGACGTTGATGGATTTGGAAAGTAATTGGCGAGATCTTCA
TTTTACTCCCAACTCTTTCCACTGCATATGACTGACTCGATTGCTTGAAGAGAAGGAAACGGCA
ATTGGAAGAGGTCCCTACCCAGACTGCTTTGGAATCATGAGAGATGAAATTGCAACAGCAGTTT
TTTTTGTCACAAGACTGGCGAAAAAGCACGAGAAACTGAGTACCCAACAGATAGAAACCTTCGC
GCTGAAGCTGATGACTGTCTTGTTTGAAAAGTACAGAGGTCACTGGCACCCTGACTGCCCTTCT
AAGGGGCAGGCTTTTAGGTGTATCAGGATAAACAACAACGAGAATAAAGACCCTGTTTTAGAAA
GGGCTTGTTCTGAGAGTAATGTGAATTTTTTTCATCTGGGACTTCCAAAGGAGATGACCATATG
GGTCGATCCCTTTGAGGTGTGCTGTAGGTATGGTGAGAAAAAGCATCCCTTCACAATTGCTTCT
TTTAAAGGTAGATGGGAGAACTGGGAATTAGCTCAGAGTGTCAGCTGTGCAGTTAACAAAGCCA
CAGGAGACTGCTCTCCCAGCGCATCTTCTGATGAGGAGAGCTGCGGCAGGGAGGCCCAGGCCAT
CCCCAAAGTGAACAACCCCAAGAGCATCTACCAGGTTGAAAACTTCAAACCGTCCTTCCAGCCG
TGGCTCTGCCTCCCCCGCAGAAAGCATTTGGCAGATGGTCATGGCTGCCTCCTGGGGGCTGCTT
ACCACCCAATGCCCAAGAACTCTAAGTGGTGCAGGCATGCTGGGCATCGGGTGGACAGGTATCA
CTGGGTCAACACACAGTTGATCAGTGGTCAGACAGCACCAGGCGAGCTTGGAGAAGAGGCCTTG
TCTTCCCGAAAGCAAAAATGAGGGTAGAGCTAAGAAATACTCCCAGTAAAAAAACACAACAAAC
AAAACAAACGGCTGCTTCGGGGATGTGAGCATACAAGGCCACCCTTGCACACAGAACTGCTTCA
GGGATGTGAGCATACAAGGCCATCCTTGCACACAGATTGCCACCTGACTTTTAGCTACTTTTAA
TTCTCATTTTACTTTATGTAACGTTTTATGAACACTAGTGAATATATGTGCCAAGTAAAGTGAT
AGAATGAAAATATTGCCTGTGATAAAATAAAATGAATTTTAGGAAGAAAGACTTGAAATAAATA
CTCTTGTGTTTTTAACAAA

hide sequence

RefSeq Acc Id:

XM_006243036 ⟹ XP_006243098

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	60,317,449 - 60,322,167 (+)	NCBI
mRatBN7.2	8	51,421,085 - 51,425,802 (+)	NCBI
Rnor_6.0	8	55,503,426 - 55,508,100 (+)	NCBI
Rnor_5.0	8	54,089,729 - 54,104,457 (+)	NCBI

Sequence:

show sequence

AAGACATGGCATGCCGGATAGCTCACATTTAGAATATCCCCTTGTGGTAGAGGATTTCTTGCAA
TCTGTGTAGTTCCAGTGTGGTTGTGTAGGCACAACATTGAGATGATGGATTTGTCTCCTTACAA
GGTCCCTACCCAGACTGCTTTGGAATCATGAGAGATGAAATTGCAACAGCAGTTTTTTTTGTCA
CAAGACTGGCGAAAAAGCACGAGAAACTGAGTACCCAACAGATAGAAACCTTCGCGCTGAAGCT
GATGACTGTCTTGTTTGAAAAGTACAGAGGTCACTGGCACCCTGACTGCCCTTCTAAGGGGCAG
GCTTTTAGGTGTATCAGGATAAACAACAACGAGAATAAAGACCCTGTTTTAGAAAGGGCTTGTT
CTGAGAGTAATGTGAATTTTTTTCATCTGGGACTTCCAAAGGAGATGACCATATGGGTCGATCC
CTTTGAGGTGTGCTGTAGGTATGGTGAGAAAAAGCATCCCTTCACAATTGCTTCTTTTAAAGGT
AGATGGGAGAACTGGGAATTAGCTCAGAGTGTCAGCTGTGCAGTTAACAAAGCCACAGGAGACT
GCTCTCCCAGCGCATCTTCTGATGAGGAGAGCTGCGGCAGGGAGGCCCAGGCCATCCCCAAAGT
GAACAACCCCAAGAGCATCTACCAGGTTGAAAACTTCAAACCGTCCTTCCAGCCGTGGCTCTGC
CTCCCCCGCAGAAAGCATTTGGCAGATGGTCATGGCTGCCTCCTGGGGGCTGCTTACCACCCAA
TGCCCAAGAACTCTAAGTGGTGCAGGCATGCTGGGCATCGGGTGGACAGGTATCACTGGGTCAA
CACACAGTTGATCAGTGGTCAGACAGCACCAGGCGAGCTTGGAGAAGAGGCCTTGTCTTCCCGA
AAGCAAAAATGAGGGTAGAGCTAAGAAATACTCCCAGTAAAAAAACACAACAAACAAAACAAAC
GGCTGCTTCGGGGATGTGAGCATACAAGGCCACCCTTGCACACAGAACTGCTTCAGGGATGTGA
GCATACAAGGCCATCCTTGCACACAGATTGCCACCTGACTTTTAGCTACTTTTAATTCTCATTT
TACTTTATGTAACGTTTTATGAACACTAGTGAATATATGTGCCAAGTAAAGTGATAGAATGAAA
ATATTGCCTGTGATAAAATAAAATGAATTTTAGGAAGAAAGACTTGAAATAAATACTCTTGTGT
TTTTAACAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001013194	(Get FASTA)	NCBI Sequence Viewer
	NP_001388023	(Get FASTA)	NCBI Sequence Viewer
	XP_006243097	(Get FASTA)	NCBI Sequence Viewer
	XP_006243098	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH88755	(Get FASTA)	NCBI Sequence Viewer
	AAY43133	(Get FASTA)	NCBI Sequence Viewer
	EDL95490	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000055863
	ENSRNOP00000055863.2
	ENSRNOP00000072007
	ENSRNOP00000072007.2

RefSeq Acc Id:	NP_001013194 ⟸ NM_001013176
- Peptide Label:	isoform 2
- UniProtKB:	Q5M7A6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRDEIATAVFFVTRLAKKHEKLSTQQIETFALKLMTVLFEKYRGHWHPDCPSKGQAFRCIRINN NENKDPVLERACSESNVNFFHLGLPKEMTIWVDPFEVCCRLKTSNRPSSRGSASPAESIWQMVM AASWGLLTTQCPRTLSGAGMLGIGWTGITGSTHS hide sequence

RefSeq Acc Id:	XP_006243097 ⟸ XM_006243035
- Peptide Label:	isoform X1
- UniProtKB:	Q4VFT8 (UniProtKB/TrEMBL), A0A0G2K1W2 (UniProtKB/TrEMBL), A0A9K3Y7H5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRDEIATAVFFVTRLAKKHEKLSTQQIETFALKLMTVLFEKYRGHWHPDCPSKGQAFRCIRINN NENKDPVLERACSESNVNFFHLGLPKEMTIWVDPFEVCCRYGEKKHPFTIASFKGRWENWELAQ SVSCAVNKATGDCSPSASSDEESCGREAQAIPKVNNPKSIYQVENFKPSFQPWLCLPRRKHLAD GHGCLLGAAYHPMPKNSKWCRHAGHRVDRYHWVNTQLISGQTAPGELGEEALSSRKQK hide sequence

RefSeq Acc Id:	XP_006243098 ⟸ XM_006243036
- Peptide Label:	isoform X1
- UniProtKB:	Q4VFT8 (UniProtKB/TrEMBL), A0A0G2K1W2 (UniProtKB/TrEMBL), A0A9K3Y7H5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRDEIATAVFFVTRLAKKHEKLSTQQIETFALKLMTVLFEKYRGHWHPDCPSKGQAFRCIRINN NENKDPVLERACSESNVNFFHLGLPKEMTIWVDPFEVCCRYGEKKHPFTIASFKGRWENWELAQ SVSCAVNKATGDCSPSASSDEESCGREAQAIPKVNNPKSIYQVENFKPSFQPWLCLPRRKHLAD GHGCLLGAAYHPMPKNSKWCRHAGHRVDRYHWVNTQLISGQTAPGELGEEALSSRKQK hide sequence

RefSeq Acc Id:

ENSRNOP00000055863 ⟸ ENSRNOT00000059086

RefSeq Acc Id:

ENSRNOP00000072007 ⟸ ENSRNOT00000088320

RefSeq Acc Id:	NP_001388023 ⟸ NM_001401094
- Peptide Label:	isoform 1
- UniProtKB:	A0A0G2K1W2 (UniProtKB/TrEMBL), A0A9K3Y7H5 (UniProtKB/TrEMBL), Q4VFT8 (UniProtKB/TrEMBL)

Protein Domains

Anti-proliferative protein

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K1W2-F1-model_v2	AlphaFold	A0A0G2K1W2	1-262	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308809	AgrOrtholog
BioCyc Gene	G2FUF-30521	BioCyc
Ensembl Genes	ENSRNOG00000011277	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000059086	ENTREZGENE
	ENSRNOT00000059086.4	UniProtKB/TrEMBL
	ENSRNOT00000088320	ENTREZGENE
	ENSRNOT00000088320.2	UniProtKB/TrEMBL
Gene3D-CATH	3.90.640.90	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7307514	IMAGE-MGC_LOAD
InterPro	Anti_prolifrtn	UniProtKB/TrEMBL
	BTG-like_sf	UniProtKB/TrEMBL
	BTG4	UniProtKB/TrEMBL
KEGG Report	rno:315650	UniProtKB/TrEMBL
MGC_CLONE	MGC:105553	IMAGE-MGC_LOAD
NCBI Gene	315650	ENTREZGENE
PANTHER	PROTEIN BTG4	UniProtKB/TrEMBL
	PTHR22978	UniProtKB/TrEMBL
Pfam	BTG	UniProtKB/TrEMBL
PhenoGen	Btg4	PhenoGen
PRINTS	ANTIPRLFBTG1	UniProtKB/TrEMBL
PROSITE	BTG_1	UniProtKB/TrEMBL
	BTG_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000011277	RatGTEx
SMART	btg1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF160696	UniProtKB/TrEMBL
UniProt	A0A0G2K1W2	ENTREZGENE
	A0A9K3Y7H5	ENTREZGENE, UniProtKB/TrEMBL
	Q4VFT8	ENTREZGENE, UniProtKB/TrEMBL
	Q5M7A6	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A0G2K1W2	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-07-13	Btg4	BTG anti-proliferation factor 4	Btg4	BTG family member 4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-12-02	Btg4	BTG family member 4	Btg4	B-cell translocation gene 4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Btg4	B-cell translocation gene 4	Btg4_predicted	B-cell translocation gene 4 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Btg4_predicted	B-cell translocation gene 4 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)