Fancm (FA complementation group M) - Rat Genome Database

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Gene: Fancm (FA complementation group M) Rattus norvegicus
Analyze
Symbol: Fancm
Name: FA complementation group M
RGD ID: 1307897
Description: Predicted to enable chromatin binding activity. Predicted to be involved in DNA metabolic process and positive regulation of protein monoubiquitination. Predicted to be located in nucleoplasm. Predicted to be part of FANCM-MHF complex; Fanconi anaemia nuclear complex; and chromatin. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 15 and spermatogenic failure 28. Orthologous to human FANCM (FA complementation group M); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; paracetamol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fanconi anemia, complementation group M; LOC314172; RGD1307897; similar to RIKEN cDNA C730036B14 gene
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8688,862,898 - 88,916,701 (+)NCBIGRCr8
mRatBN7.2683,126,903 - 83,180,455 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl683,127,093 - 83,180,028 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0686,823,195 - 86,877,067 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl686,823,684 - 86,876,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0696,312,237 - 96,365,616 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4686,424,156 - 86,476,902 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1686,462,951 - 86,480,559 (+)NCBI
Celera681,694,524 - 81,748,389 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma. Wreesmann VB, etal., ORL J Otorhinolaryngol Relat Spec. 2007;69(4):218-25. Epub 2007 Apr 4.
Additional References at PubMed
PMID:12477932   PMID:20347428   PMID:20347429   PMID:29231814  


Genomics

Comparative Map Data
Fancm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8688,862,898 - 88,916,701 (+)NCBIGRCr8
mRatBN7.2683,126,903 - 83,180,455 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl683,127,093 - 83,180,028 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0686,823,195 - 86,877,067 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl686,823,684 - 86,876,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0696,312,237 - 96,365,616 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4686,424,156 - 86,476,902 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1686,462,951 - 86,480,559 (+)NCBI
Celera681,694,524 - 81,748,389 (+)NCBICelera
Cytogenetic Map6q24NCBI
FANCM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381445,135,930 - 45,200,890 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1445,135,930 - 45,200,890 (+)EnsemblGRCh38hg38GRCh38
GRCh371445,605,133 - 45,670,093 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361444,674,886 - 44,739,840 (+)NCBINCBI36Build 36hg18NCBI36
Celera1425,466,389 - 25,531,345 (+)NCBICelera
Cytogenetic Map14q21.2NCBI
HuRef1425,716,007 - 25,780,814 (+)NCBIHuRef
CHM1_11445,543,284 - 45,608,236 (+)NCBICHM1_1
T2T-CHM13v2.01439,327,942 - 39,392,898 (+)NCBIT2T-CHM13v2.0
Fancm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391265,120,884 - 65,178,616 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1265,122,377 - 65,178,832 (+)EnsemblGRCm39 Ensembl
GRCm381265,074,110 - 65,131,842 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1265,075,603 - 65,132,058 (+)EnsemblGRCm38mm10GRCm38
MGSCv371266,176,593 - 66,233,045 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361265,994,211 - 66,050,663 (+)NCBIMGSCv36mm8
Celera1266,205,293 - 66,261,759 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1227.21NCBI
Fancm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540916,751,658 - 16,809,352 (-)NCBIChiLan1.0ChiLan1.0
FANCM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21546,307,022 - 46,373,092 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11445,523,532 - 45,589,603 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01425,752,295 - 25,817,001 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11444,080,146 - 44,143,958 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1444,080,146 - 44,143,958 (+)Ensemblpanpan1.1panPan2
FANCM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1822,561,862 - 22,625,077 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl822,562,147 - 22,623,994 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha822,379,967 - 22,443,217 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0822,721,187 - 22,784,324 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl822,721,241 - 22,782,983 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1822,383,584 - 22,446,699 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0822,449,937 - 22,513,049 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0822,785,967 - 22,848,837 (+)NCBIUU_Cfam_GSD_1.0
Fancm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864054,543,349 - 54,604,838 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365834,085,802 - 4,145,621 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FANCM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1175,334,141 - 175,400,685 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11175,333,965 - 175,402,065 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21195,220,132 - 195,287,229 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FANCM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12422,255,750 - 22,327,191 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2422,256,236 - 22,329,609 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666116215,894 - 286,697 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fancm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473123,340,460 - 23,392,040 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473123,342,313 - 23,391,877 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fancm
132 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat

Markers in Region
D6Got109  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2683,161,747 - 83,162,010 (+)MAPPERmRatBN7.2
Rnor_6.0686,858,364 - 86,858,626NCBIRnor6.0
Rnor_5.0696,347,343 - 96,347,605UniSTSRnor5.0
RGSC_v3.4686,458,835 - 86,459,098RGDRGSC3.4
RGSC_v3.4686,458,836 - 86,459,098UniSTSRGSC3.4
RGSC_v3.1686,462,292 - 86,462,554RGD
Celera681,729,686 - 81,729,948UniSTS
RH 3.4 Map6550.8UniSTS
RH 3.4 Map6550.8RGD
RH 2.0 Map6796.1RGD
Cytogenetic Map6q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6 32 16 18 16 61 20 32 5
Low 3 37 25 25 1 25 8 10 13 15 9 6 8
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001025005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001427663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_056985575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_056985576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_056985577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_056985578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_056985579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_056985580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_056985581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_234239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001838440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001844057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_347272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_347273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_347274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_347275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_347276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_354854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_593053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_601463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_601464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC091339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000006574   ⟹   ENSRNOP00000006574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl686,823,688 - 86,852,282 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000059244   ⟹   ENSRNOP00000056011
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl686,852,323 - 86,876,633 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086081   ⟹   ENSRNOP00000074177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl683,127,093 - 83,180,028 (+)Ensembl
Rnor_6.0 Ensembl686,823,684 - 86,876,599 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086894   ⟹   ENSRNOP00000073969
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl686,872,903 - 86,876,633 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl686,871,430 - 86,873,062 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000088683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl686,866,374 - 86,871,703 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093492   ⟹   ENSRNOP00000076245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl683,166,147 - 83,177,099 (+)Ensembl
Rnor_6.0 Ensembl686,862,790 - 86,873,711 (+)Ensembl
RefSeq Acc Id: NM_001427663   ⟹   NP_001414592
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,863,316 - 88,916,701 (+)NCBI
RefSeq Acc Id: XM_056985575   ⟹   XP_056841555
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,862,901 - 88,916,024 (+)NCBI
mRatBN7.2683,127,167 - 83,180,025 (+)NCBI
RefSeq Acc Id: XM_056985576   ⟹   XP_056841556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,862,901 - 88,916,271 (+)NCBI
mRatBN7.2683,127,167 - 83,179,037 (+)NCBI
RefSeq Acc Id: XM_056985577   ⟹   XP_056841557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,862,901 - 88,916,024 (+)NCBI
mRatBN7.2683,127,167 - 83,179,778 (+)NCBI
RefSeq Acc Id: XM_056985578   ⟹   XP_056841558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,862,901 - 88,916,271 (+)NCBI
mRatBN7.2683,127,167 - 83,179,819 (+)NCBI
RefSeq Acc Id: XM_056985579   ⟹   XP_056841559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,862,898 - 88,909,141 (+)NCBI
mRatBN7.2683,127,167 - 83,174,670 (+)NCBI
RefSeq Acc Id: XM_056985580   ⟹   XP_056841560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,862,898 - 88,916,027 (+)NCBI
mRatBN7.2683,127,167 - 83,179,787 (+)NCBI
RefSeq Acc Id: XM_056985581   ⟹   XP_056841561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,862,899 - 88,911,427 (+)NCBI
mRatBN7.2683,127,167 - 83,175,181 (+)NCBI
RefSeq Acc Id: XM_063261918   ⟹   XP_063117988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,862,901 - 88,916,271 (+)NCBI
RefSeq Acc Id: XM_063261919   ⟹   XP_063117989
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,862,901 - 88,916,271 (+)NCBI
RefSeq Acc Id: XM_063261920   ⟹   XP_063117990
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,862,901 - 88,912,770 (+)NCBI
RefSeq Acc Id: XM_063261921   ⟹   XP_063117991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,862,901 - 88,912,502 (+)NCBI
RefSeq Acc Id: XM_063261922   ⟹   XP_063117992
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,862,898 - 88,912,706 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000006574   ⟸   ENSRNOT00000006574
RefSeq Acc Id: ENSRNOP00000076245   ⟸   ENSRNOT00000093492
RefSeq Acc Id: ENSRNOP00000073969   ⟸   ENSRNOT00000086894
RefSeq Acc Id: ENSRNOP00000056011   ⟸   ENSRNOT00000059244
RefSeq Acc Id: ENSRNOP00000074177   ⟸   ENSRNOT00000086081
RefSeq Acc Id: XP_056841555   ⟸   XM_056985575
- Peptide Label: isoform X1
RefSeq Acc Id: XP_056841558   ⟸   XM_056985578
- Peptide Label: isoform X4
RefSeq Acc Id: XP_056841560   ⟸   XM_056985580
- Peptide Label: isoform X9
RefSeq Acc Id: XP_056841557   ⟸   XM_056985577
- Peptide Label: isoform X3
RefSeq Acc Id: XP_056841556   ⟸   XM_056985576
- Peptide Label: isoform X3
RefSeq Acc Id: XP_056841561   ⟸   XM_056985581
- Peptide Label: isoform X10
RefSeq Acc Id: XP_056841559   ⟸   XM_056985579
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063117992   ⟸   XM_063261922
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063117989   ⟸   XM_063261919
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063117988   ⟸   XM_063261918
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063117990   ⟸   XM_063261920
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063117991   ⟸   XM_063261921
- Peptide Label: isoform X6
RefSeq Acc Id: NP_001414592   ⟸   NM_001427663
- UniProtKB: A0A0G2K7F0 (UniProtKB/TrEMBL)
Protein Domains
ERCC4   Helicase ATP-binding   Helicase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K7F0-F1-model_v2 AlphaFold A0A0G2K7F0 1-2017 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694628
Promoter ID:EPDNEW_R5151
Type:multiple initiation site
Name:Fancm_1
Description:Fanconi anemia, complementation group M
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0686,823,669 - 86,823,729EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307897 AgrOrtholog
BioCyc Gene G2FUF-37319 BioCyc
Ensembl Genes ENSRNOG00000056721 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000086081.2 UniProtKB/TrEMBL
  ENSRNOT00000093492.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10130 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  5' to 3' exonuclease, C-terminal subdomain UniProtKB/TrEMBL
  hef helicase domain UniProtKB/TrEMBL
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  ERCC4_domain UniProtKB/TrEMBL
  FANCM-MHF-bd UniProtKB/TrEMBL
  FANCM/Mph1-like UniProtKB/TrEMBL
  FANCM_DEXDc UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Restrict_endonuc_II-like_core UniProtKB/TrEMBL
  RuvA_2-like UniProtKB/TrEMBL
  XPF_nuclease_FANCM UniProtKB/TrEMBL
NCBI Gene Fancm ENTREZGENE
PANTHER FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER UniProtKB/TrEMBL
  PTHR14025:SF20 UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  ERCC4 UniProtKB/TrEMBL
  FANCM-MHF_bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PhenoGen Fancm PhenoGen
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
RatGTEx ENSRNOG00000056721 RatGTEx
SMART DEXDc UniProtKB/TrEMBL
  ERCC4 UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP Restrict_endonuc_II-like_core UniProtKB/TrEMBL
  SSF47781 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2K7F0 ENTREZGENE, UniProtKB/TrEMBL
  A0A1W2Q6G5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-25 Fancm  FA complementation group M  Fancm  Fanconi anemia, complementation group M  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-07-29 Fancm  Fanconi anemia, complementation group M  RGD1307897  similar to RIKEN cDNA C730036B14 gene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1307897  similar to RIKEN cDNA C730036B14 gene  RGD1307897_predicted  similar to RIKEN cDNA C730036B14 gene (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1307897_predicted  similar to RIKEN cDNA C730036B14 gene (predicted)  LOC314172_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314172_predicted  similar to RIKEN cDNA C730036B14 gene (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL