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Gene: Gas8 (growth arrest specific 8) Rattus norvegicus
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Symbol: Gas8
Name: growth arrest specific 8
Description: Predicted to have Rab GTPase binding activity and microtubule binding activity. Predicted to be involved in several processes, including cilium-dependent cell motility; positive regulation of protein localization to cilium; and positive regulation of smoothened signaling pathway. Predicted to localize to the Golgi apparatus; cilium; and cytoskeleton. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 33. Orthologous to human GAS8 (growth arrest specific 8); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: dynein regulatory complex subunit 4; GAS-11; GAS-8; growth arrest-specific protein 11; growth arrest-specific protein 8; LOC361438; MGC124779
Orthologs:
Homo sapiens (human) : GAS8 (growth arrest specific 8)  HGNC  Alliance
Mus musculus (house mouse) : Gas8 (growth arrest specific 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gas8 (growth arrest specific 8)
Pan paniscus (bonobo/pygmy chimpanzee) : GAS8 (growth arrest specific 8)
Canis lupus familiaris (dog) : GAS8 (growth arrest specific 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gas8 (growth arrest specific 8)
Sus scrofa (pig) : GAS8 (growth arrest specific 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01956,316,367 - 56,335,873 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01967,025,533 - 67,045,034 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41953,838,508 - 53,852,302 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11953,845,757 - 53,862,677 (+)NCBI
Celera1950,784,247 - 50,803,673 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gas8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307817
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.