Snta1 (syntrophin, alpha 1) - Rat Genome Database

Name: Snta1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Snta1 (syntrophin, alpha 1) Rattus norvegicus

Analyze

Symbol:

Snta1

Name:

syntrophin, alpha 1

RGD ID:

1307068

Description:

Enables PDZ domain binding activity. Predicted to be involved in several processes, including negative regulation of peptidyl-cysteine S-nitrosylation; regulation of ventricular cardiac muscle cell membrane repolarization; and ventricular cardiac muscle cell action potential. Predicted to act upstream of or within neuromuscular junction development and regulation of vasoconstriction by circulating norepinephrine. Located in neuromuscular junction and sarcolemma. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in long QT syndrome; long QT syndrome 12; and sudden infant death syndrome. Orthologous to human SNTA1 (syntrophin alpha 1); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

alpha-1-syntrophin; LOC362242; syntrophin, acidic 1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SNTA1 (syntrophin alpha 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Snta1 (syntrophin, acidic 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Snta1 (syntrophin alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SNTA1 (syntrophin alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SNTA1 (syntrophin alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Snta1 (syntrophin alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CDK5RAP1 (CDK5 regulatory subunit associated protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SNTA1 (syntrophin alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Snta1 (syntrophin alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SNTA1 (syntrophin alpha 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Snta1 (syntrophin, acidic 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	snta1 (syntrophin, alpha 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Syn1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	stn-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	snta1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	163,336,509 - 163,366,954 (-)	NCBI		GRCr8
mRatBN7.2	3	142,876,285 - 142,906,737 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	142,876,296 - 142,906,709 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	146,743,646 - 146,773,763 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	155,361,813 - 155,391,929 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	153,101,175 - 153,131,287 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	149,874,023 - 149,905,980 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	149,874,030 - 149,905,944 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	156,245,190 - 156,278,486 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	144,843,678 - 144,874,238 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	144,749,301 - 144,779,860 (-)	NCBI
Celera	3	141,611,616 - 141,641,783 (-)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atrial fibrillation (ISO)

Becker muscular dystrophy (ISO)

Brugada syndrome (ISO)

dilated cardiomyopathy (ISO)

dilated cardiomyopathy 3B (ISO)

Duchenne muscular dystrophy (ISO)

genetic disease (ISO)

long QT syndrome (ISO)

long QT syndrome 1 (ISO)

long QT syndrome 12 (ISO)

long QT syndrome 2 (ISO)

Romano-Ward Syndrome (ISO)

sick sinus syndrome (ISO)

status epilepticus (IEP,ISO)

sudden infant death syndrome (ISO)

Sudden Unexpected Nocturnal Death Syndrome (ISO)

Ventricular Fibrillation (ISO)

Ventricular Fibrillation, Paroxysmal Familial, 1 (ISO)

Ventricular Tachycardia (ISO)

Wolff-Parkinson-White syndrome (ISO)

X-linked dilated cardiomyopathy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-pilocarpine (EXP)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3-chloropropane-1,2-diol (EXP)

4-hydroxyphenyl retinamide (ISO)

acrylamide (EXP)

amitrole (EXP)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

C60 fullerene (EXP)

caffeine (ISO)

carbon nanotube (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

dexamethasone (ISO)

diquat (ISO)

disodium selenite (ISO)

doxorubicin (ISO)

entinostat (ISO)

folic acid (ISO)

FR900359 (ISO)

genistein (EXP)

gentamycin (EXP)

graphite (EXP)

ketamine (EXP)

lead(0) (ISO)

menadione (ISO)

methamphetamine (ISO)

methimazole (EXP)

N-methyl-4-phenylpyridinium (ISO)

naphthalene (ISO)

nitric oxide (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

pyrogallol (ISO)

resveratrol (ISO)

S-butyl-DL-homocysteine (S,R)-sulfoximine (ISO)

sodium arsenite (ISO)

Soman (EXP)

succimer (ISO)

sulfadimethoxine (EXP)

testosterone (ISO)

thioacetamide (EXP)

triclosan (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

negative regulation of peptidyl-cysteine S-nitrosylation (ISO)

neuromuscular junction development (ISO)

regulation of heart rate (ISO)

regulation of sodium ion transmembrane transport (ISO)

regulation of vasoconstriction by circulating norepinephrine (ISO)

regulation of ventricular cardiac muscle cell membrane repolarization (ISO)

ventricular cardiac muscle cell action potential (ISO)

Cellular Component

cytoskeleton (IEA)

dystrophin-associated glycoprotein complex (IBA)

neuromuscular junction (IBA,IDA)

postsynaptic membrane (ISO)

protein-containing complex (ISO)

sarcolemma (IBA,IDA,ISO)

Molecular Function

ATPase binding (ISO)

nitric-oxide synthase binding (ISO)

PDZ domain binding (IPI)

protein binding (ISO)

sodium channel regulator activity (ISO)

structural molecule activity (IEA)

transmembrane transporter binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

acebutolol pharmacodynamics pathway (ISO)

adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway (ISO)

amiodarone pharmacodynamics pathway (ISO)

amlodipine pharmacodynamics pathway (ISO)

atenolol pharmacodynamics pathway (ISO)

betaxolol pharmacodynamics pathway (ISO)

bisoprolol pharmacodynamics pathway (ISO)

bupranolol drug pathway (ISO)

bupranolol pharmacodynamics pathway (ISO)

carvedilol pharmacodynamics pathway (ISO)

diltiazem pharmacodynamics pathway (ISO)

disopyramide pharmacodynamics pathway (ISO)

dobutamine pharmacodynamics pathway (ISO)

esmolol pharmacodynamics pathway (ISO)

flecainde pharmacodynamics pathway (ISO)

fosphenytoin pharmacodynamics pathway (ISO)

fosphenytoin pharmacokinetics pathway (ISO)

ibutilide pharmacodynamics pathway (ISO)

isoprenaline pharmacodynamics pathway (ISO)

isradipine pharmacodynamics pathway (ISO)

levobunolol pharmacodynamics pathway (ISO)

lidocaine pharmacodynamics pathway (ISO)

metoprolol pharmacodynamics pathway (ISO)

mexiletine pharmacodynamics pathway (ISO)

nadolol pharmacodynamics pathway (ISO)

nebivolol pharmacodynamics pathway (ISO)

nifedipine pharmacodynamics pathway (ISO)

nimodipine pharmacodynamics pathway (ISO)

nisoldipine pharmacodynamics pathway (ISO)

nitrendipine pharmacodynamics pathway (ISO)

penbutolol pharmacodynamics pathway (ISO)

phenytoin pharmacodynamics pathway (ISO)

pindolol pharmacodynamics pathway (ISO)

procainamide pharmacodynamics pathway (ISO)

propranolol pharmacodynamics pathway (ISO)

quinidine pharmacodynamics pathway (ISO)

sotalol pharmacodynamics pathway (ISO)

timolol pharmacodynamics pathway (ISO)

verapamil pharmacodynamics pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Alpha1-syntrophin mutations identified in sudden infant death syndrome cause an increase in late cardiac sodium current.	Cheng J, etal., Circ Arrhythm Electrophysiol. 2009 Dec;2(6):667-76. Epub .
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Astroglial loss and edema formation in the rat piriform cortex and hippocampus following pilocarpine-induced status epilepticus.	Kim JE, etal., J Comp Neurol. 2010 Nov 15;518(22):4612-28.
5.	MLC1 trafficking and membrane expression in astrocytes: role of caveolin-1 and phosphorylation.	Lanciotti A, etal., Neurobiol Dis. 2010 Mar;37(3):581-95. Epub 2009 Nov 26.
6.	Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.	Leonoudakis D, etal., J Biol Chem. 2004 May 21;279(21):22331-46. Epub 2004 Mar 15.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
9.	beta 2-Syntrophin: localization at the neuromuscular junction in skeletal muscle.	Peters MF, etal., Neuroreport. 1994 Aug 15;5(13):1577-80.
10.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
11.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
13.	Comprehensive gene review and curation	RGD comprehensive gene curation
14.	alpha-1-syntrophin mutation and the long-QT syndrome: a disease of sodium channel disruption.	Wu G, etal., Circ Arrhythm Electrophysiol. 2008 Aug;1(3):193-201.

Additional References at PubMed

PMID:10995443	PMID:11043403	PMID:11115849	PMID:11717465	PMID:12477932	PMID:12600881	PMID:16935300	PMID:17628813	PMID:18591664	PMID:25931508

Genomics

Comparative Map Data

Snta1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	163,336,509 - 163,366,954 (-)	NCBI		GRCr8
mRatBN7.2	3	142,876,285 - 142,906,737 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	142,876,296 - 142,906,709 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	146,743,646 - 146,773,763 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	155,361,813 - 155,391,929 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	153,101,175 - 153,131,287 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	149,874,023 - 149,905,980 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	149,874,030 - 149,905,944 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	156,245,190 - 156,278,486 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	144,843,678 - 144,874,238 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	144,749,301 - 144,779,860 (-)	NCBI
Celera	3	141,611,616 - 141,641,783 (-)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

SNTA1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	33,407,957 - 33,443,763 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	33,407,957 - 33,443,763 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	31,995,763 - 32,031,569 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	31,459,424 - 31,495,359 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	31,459,423 - 31,495,359	NCBI
Celera	20	28,749,527 - 28,785,451 (-)	NCBI		Celera
Cytogenetic Map	20	q11.21	NCBI
HuRef	20	28,783,561 - 28,819,451 (-)	NCBI		HuRef
CHM1_1	20	31,896,842 - 31,932,765 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	20	35,135,186 - 35,170,977 (-)	NCBI		T2T-CHM13v2.0

Snta1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	154,218,234 - 154,250,004 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	154,218,233 - 154,250,019 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	154,376,313 - 154,408,107 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	154,376,313 - 154,408,099 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	154,202,050 - 154,233,820 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	154,067,769 - 154,099,522 (-)	NCBI		MGSCv36	mm8
Celera	2	160,280,592 - 160,313,658 (-)	NCBI		Celera
Cytogenetic Map	2	H1	NCBI
cM Map	2	76.52	NCBI

Snta1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	27,844,853 - 27,871,547 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	27,844,699 - 27,872,104 (+)	NCBI	ChiLan1.0	ChiLan1.0

SNTA1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	39,099,698 - 39,135,847 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	39,092,798 - 39,128,921 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	29,696,137 - 29,732,258 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	30,810,787 - 30,844,472 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	30,810,787 - 30,844,476 (-)	Ensembl	panpan1.1		panPan2

SNTA1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	22,636,716 - 22,665,828 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	22,636,756 - 22,665,741 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	22,281,583 - 22,313,637 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	23,322,134 - 23,354,134 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	23,322,133 - 23,354,191 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	22,597,383 - 22,628,609 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	22,708,067 - 22,740,033 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	23,139,650 - 23,170,903 (-)	NCBI		UU_Cfam_GSD_1.0

Snta1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	171,615,021 - 171,653,713 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936561	7,101,654 - 7,133,988 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936561	7,101,654 - 7,134,529 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDK5RAP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	36,915,953 - 36,946,187 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	36,917,276 - 36,946,232 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	41,867,614 - 41,896,571 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SNTA1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	37,703,002 - 37,737,529 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	37,702,971 - 37,737,423 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	89,152,431 - 89,194,359 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Snta1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624842	5,805,342 - 5,834,022 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624842	5,805,409 - 5,834,553 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Snta1
109 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	62
Count of miRNA genes:	56
Interacting mature miRNAs:	57
Transcripts:	ENSRNOT00000021715
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	97551417	147415807	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
619618	Rf3	Renal disease susceptibility QTL 3	6.5	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate to body weight ratio (CMO:0001270)	3	107693393	152693393	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	112681431	157681431	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	118839124	163839124	Rat
1598877	Bp285	Blood pressure QTL 285	1.5	0.03	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	120538241	165538241	Rat
1300173	Rf11	Renal function QTL 11	3.38		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	121056165	145956249	Rat
1300159	Kidm4	Kidney mass QTL 4	3.83		kidney mass (VT:0002707)	right kidney wet weight to body weight ratio (CMO:0001953)	3	121056165	157309487	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	122438700	167438700	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	124122556	169034231	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	127162703	168026850	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	130193298	161695983	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	130656562	169034231	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	130656562	169034231	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	131635904	169034231	Rat
2298477	Eau4	Experimental allergic uveoretinitis QTL 4		0.0011	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	3	137398739	169034231	Rat
8552952	Pigfal13	Plasma insulin-like growth factor 1 level QTL 13			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	138799500	169034231	Rat
5686842	Rf59	Renal function QTL 59			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	3	140069424	146976080	Rat
1298068	Bp167	Blood pressure QTL 167		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	141074471	169034231	Rat
1331726	Bp208	Blood pressure QTL 208	3.129		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141339013	162184794	Rat
61335	Bp20	Blood pressure QTL 20	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	141339236	155617360	Rat

Markers in Region

U00677

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	142,876,653 - 142,876,733 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	149,874,388 - 149,874,467	NCBI	Rnor6.0
Rnor_5.0	3	156,245,559 - 156,245,638	UniSTS	Rnor5.0
RGSC_v3.4	3	144,844,039 - 144,844,118	UniSTS	RGSC3.4
Celera	3	141,611,977 - 141,612,056	UniSTS
Cytogenetic Map	3	q41	UniSTS

RH134532

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	142,876,382 - 142,876,576 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	149,874,117 - 149,874,310	NCBI	Rnor6.0
Rnor_5.0	3	156,245,288 - 156,245,481	UniSTS	Rnor5.0
RGSC_v3.4	3	144,843,768 - 144,843,961	UniSTS	RGSC3.4
Celera	3	141,611,706 - 141,611,899	UniSTS
RH 3.4 Map	3	1294.8	UniSTS
Cytogenetic Map	3	q41	UniSTS

AU048638

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	142,879,770 - 142,880,170 (+)	MAPPER	mRatBN7.2
mRatBN7.2	3	142,879,945 - 142,880,170 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	149,877,682 - 149,877,906	NCBI	Rnor6.0
Rnor_6.0	3	149,877,505 - 149,877,906	NCBI	Rnor6.0
Rnor_5.0	3	156,248,676 - 156,249,077	UniSTS	Rnor5.0
Rnor_5.0	3	156,248,853 - 156,249,077	UniSTS	Rnor5.0
RGSC_v3.4	3	144,847,156 - 144,847,557	UniSTS	RGSC3.4
RGSC_v3.4	3	144,847,333 - 144,847,557	UniSTS	RGSC3.4
Celera	3	141,615,104 - 141,615,330	UniSTS
Cytogenetic Map	3	q41	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		43	11	3		3	8	11	37	29	23	7	8
Low	3		46	38	19	38			37	6	18	4
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001100901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006235326	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC100086	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC169101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474050	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000021715 ⟹ ENSRNOP00000021715

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	142,876,296 - 142,906,709 (-)	Ensembl
Rnor_6.0 Ensembl	3	149,874,030 - 149,905,944 (-)	Ensembl

RefSeq Acc Id:

NM_001100901 ⟹ NP_001094371

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	163,336,513 - 163,366,927 (-)	NCBI
mRatBN7.2	3	142,876,293 - 142,906,709 (-)	NCBI
Rnor_6.0	3	149,874,027 - 149,905,944 (-)	NCBI
Rnor_5.0	3	156,245,190 - 156,278,486 (-)	NCBI
RGSC_v3.4	3	144,843,678 - 144,874,238 (-)	RGD
Celera	3	141,611,616 - 141,641,783 (-)	RGD

Sequence:

show sequence

GTGGCGGCTGGCTCTGCTGCCCCGCCGCCCTCTGCCCTGGGCGCTGGGTCGGAGCGGGCCGGGT
ACGGCGGGACCGGGCGAGCGCAGCGTACTGGGACTTCGAGGCGAAGATGGCGTCAGGCAGGCGC
GCTCCGCGCACCGGGTTGCTAGAACTGCGCTCCGGGGCGGGCTCCGGGGCGGGTGGTGAGCGGT
GGCAGCGGGTGTTGCTCACTCTGGCGGAGGACGCGCTGACCGTGAGCCCCGCCGACGGCGAGCC
CGGCCCGGAGCCCGAGCCCGCGCAGCTCAACGGCGCCGCTGAGCCCGGCGCGGCGTCCCCACAG
CTGCCAGAGGCGCTGCTGCTCCAGCGGCGCCGCGTGACGGTGCGCAAGGCCGACGCCGGCGGGC
TCGGCATCAGCATCAAGGGAGGCCGGGAAAACAAGATGCCTATTCTCATTTCCAAGATCTTCAA
GGGGCTGGCAGCAGACCAGACGGAGGCCCTCTTTGTCGGCGATGCCATCCTCTCTGTGAATGGT
GAAGATTTGTCCTCTGCCACCCATGATGAAGCAGTACAGGCCCTCAAGAAGACGGGCAAGGAGG
TTGTGTTGGAGGTTAAGTATATGAAGGAGGTCTCACCGTATTTCAAGAATTCTGCTGGTGGGAC
CTCCGTTGGCTGGGACTCACCTCCTGCCTCGCCTCTTCAGCGTCAGCCTTCTTCCCCTGGCCCC
CAACCCCGGAACCTCAATGAGGCCAAACATGTATCTTTGAAGATGGCGTATGTCTCAAGGAGGT
GTACCCCCACTGACCCGGAGCCCAGGTATCTGGAGATCTGTGCAGCAGATGGCCAGGACACTCT
CTTCTTGAGGGCCAAGGATGAGGCCAGTGCAAGGTCATGGGCAGGTGCCATCCAAGCTCAGATC
AGCACATTTATACCTTGGGTCAAGGATGAGCTGCAGGCGCTGCTGACAGCCACAGGTACAGCTG
GGAGCCAGGACATCAAGCAGATTGGCTGGCTCACGGAACAGTTGCCCAGTGGGGGTACAGCACC
AACCCTGGCCCTGCTGACTGAGAAGGAGCTGCTCCTCTACTGCTCTCTCCCCCAGACTCGAGAG
GCCCTGAGCAGGCCGGCCCGCACTGCCCCGCTCATTGCCACCAGGCTGGTGCACTCAGGCCCTT
CCAAGGGCTCAGTGCCCTATGATGCAGAGCTCTCCTTTGCCCTGCGCACGGGTACACGCCACGG
TGTGGACACTCACCTGTTCAGTGTGGAGTCGCCGCAGGAGCTGGCAGCCTGGACCCGACAGTTG
GTGGATGGCTGTCACCGGGCTGCTGAAGGTGTGCAAGAAGTGTCTACAGCCTGCACGTGGAATG
GCCGTCCCTGCAACCTATCCGTGCACATTGACAAGGGCTTCACACTGTGGGCAGCTGAGCCAGG
AGCAACCCGAGCTGTGCTGCTCCGACAGCCCTTTGAGAAACTTCAGATGTCATCAGATGATGGC
ATGAGTCTCCTTTTCCTGGACTTTGGGGGTGCTGAAGGAGAGATCCAGCTGGACCTGCATTCGT
GTCCCAAAACCATGGTCTTTATCATCCACTCTTTCCTGTCTGCCAAGGTCACCCGCTTGGGGCT
CTTGGCCTAGAAGTTGTCAGGTGAACTAGGCCTGAAGAGGAACGTTCATCTTGTGACCTGACCC
GTCCTTCTGCTGACTGCCTGCTCATCTGTGGGCTGAGGGAAGGGAGAGGAGGGGAACTAGGGCC
TCAGAGACCAACCTGAGGAAGCAGAACTCAGACCTGGGACAGTGAGTCTGGCTTGTGATGGGGC
AGCCTTCCTACTGCTCACCTCCACCAGTGCCTTTCGAAGAGAGATATTTTGTGTACACAGAAGC
CATTCCGAGGCTGGGACCTGACCCTGTGGGGATCCATCCCATCTCCAGTCAACAGCAGAGCTGC
CACGCCTCCTGGAGGCCCCTAAGCCACCCTGAGATCTCTGCAGATGGAGTCTTCTGGGTCAGTG
GCAAGAGGAGGAAGAGGAGCCTTTCTGTTCACTCTCCCTTGGGCCCTGAGGGCTGTCTGGGCTC
TCTCCTCCTCTCTCTCCTTCCTCTTGATAATAAACAGCCTGTGAGCACATAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006235326 ⟹ XP_006235388

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	163,336,509 - 163,366,954 (-)	NCBI
mRatBN7.2	3	142,876,285 - 142,906,737 (-)	NCBI
Rnor_6.0	3	149,874,023 - 149,905,980 (-)	NCBI
Rnor_5.0	3	156,245,190 - 156,278,486 (-)	NCBI

Sequence:

show sequence

GTCCTGCGAAGCTCCGCCCCCGAGGCCCGGGGAAGGGTGGCGGCTGGCTCTGCTGCCCCGCCGC
CCTCTGCCCTGGGCGCTGGGTCGGAGCGGGCCGGGTACGGCGGGACCGGGCGAGCGCAGCGTAC
TGGGACTTCGAGGCGAAGATGGCGTCAGGCAGGCGCGCTCCGCGCACCGGGTTGCTAGAACTGC
GCTCCGGGGCGGGCTCCGGGGCGGGTGGTGAGCGGTGGCAGCGGGTGTTGCTCACTCTGGCGGA
GGACGCGCTGACCGTGAGCCCCGCCGACGGCGAGCCCGGCCCGGAGCCCGAGCCCGCGCAGCTC
AACGGCGCCGCTGAGCCCGGCGCGGCGTCCCCACAGCTGCCAGAGGCGCTGCTGCTCCAGCGGC
GCCGCGTGACGGTGCGCAAGGCCGACGCCGGCGGGCTCGGCATCAGCATCAAGGGAGGCCGGGA
AAACAAGATGCCTATTCTCATTTCCAAGATCTTCAAGGGGCTGGCAGCAGACCAGACGGAGGCC
CTCTTTGTCGGCGATGCCATCCTCTCTGTGAATGGTGAAGATTTGTCCTCTGCCACCCATGATG
AAGCAGTACAGGCCCTCAAGAAGACGGGCAAGGAGGTTGTGTTGGAGGTTAAGTATATGAAGGA
GGTCTCACCGTATTTCAAGAATTCTGCTGGTGGGACCTCCGTTGGCTGGGACTCACCTCCTGCC
TCGCCTCTTCAGCGTCAGCCTTCTTCCCCTGGCCCCCAACCCCGGAACCTCAATGAGGCCAAAC
ATGTATCTTTGAAGATGGCGTATGTCTCAAGGAGGTGTACCCCCACTGACCCGGAGCCCAGGTA
TCTGGAGATCTGTGCAGCAGATGGCCAGGACACTCTCTTCTTGAGGGCCAAGGATGAGGCCAGT
GCAAGGTCATGGGCAGGTGCCATCCAAGCTCAGATCAGCACATTTATACCTTGGGTCAAGGATG
AGCTGCAGGCGCTGCTGACAGCCACAGGTACAGCTGGGAGCCAGGACATCAAGCAGATTGGCTG
GCTCACGGAACAGTTGCCCAGTGGGGGTACAGCACCAACCCTGGCCCTGCTGACTGAGAAGGAG
CTGCTCCTCTACTGCTCTCTCCCCCAGACTCGAGAGGCCCTGAGCAGGCCGGCCCGCACTGCCC
CGCTCATTGCCACCAGGCTGGTGCACTCAGGCCCTTCCAAGGGCTCAGTGCCCTATGATGCAGA
GCTCTCCTTTGCCCTGCGCACGGGTACACGCCACGGTGTGGACACTCACCTGTTCAGTGTGGAG
TCGCCGCAGGAGCTGGCAGCCTGGACCCGACAGTTGGTGGATGGCTGTCACCGGGCTGCTGAAG
CCTGCACGTGGAATGGCCGTCCCTGCAACCTATCCGTGCACATTGACAAGGGCTTCACACTGTG
GGCAGCTGAGCCAGGAGCAACCCGAGCTGTGCTGCTCCGACAGCCCTTTGAGAAACTTCAGATG
TCATCAGATGATGGCATGAGTCTCCTTTTCCTGGACTTTGGGGGTGCTGAAGGAGAGATCCAGC
TGGACCTGCATTCGTGTCCCAAAACCATGGTCTTTATCATCCACTCTTTCCTGTCTGCCAAGGT
CACCCGCTTGGGGCTCTTGGCCTAGAAGTTGTCAGGTGAACTAGGCCTGAAGAGGAACGTTCAT
CTTGTGACCTGACCCGTCCTTCTGCTGACTGCCTGCTCATCTGTGGGCTGAGGGAAGGGAGAGG
AGGGGAACTAGGGCCTCAGAGACCAACCTGAGGAAGCAGAACTCAGACCTGGGACAGTGAGTCT
GGCTTGTGATGGGGCAGCCTTCCTACTGCTCACCTCCACCAGTGCCTTTCGAAGAGAGATATTT
TGTGTACACAGAAGCCATTCCGAGGCTGGGACCTGACCCTGTGGGGATCCATCCCATCTCCAGT
CAACAGCAGAGCTGCCACGCCTCCTGGAGGCCCCTAAGCCACCCTGAGATCTCTGCAGATGGAG
TCTTCTGGGTCAGTGGCAAGAGGAGGAAGAGGAGCCTTTCTGTTCACTCTCCCTTGGGCCCTGA
GGGCTGTCTGGGCTCTCTCCTCCTCTCTCTCCTTCCTCTTGATAATAAACAGCCTATGAGCACA
TAGGCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001094371	(Get FASTA)	NCBI Sequence Viewer
	XP_006235388	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI00087	(Get FASTA)	NCBI Sequence Viewer
	AAI69101	(Get FASTA)	NCBI Sequence Viewer
	EDL85970	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021715
	ENSRNOP00000021715.6

RefSeq Acc Id:

NP_001094371 ⟸ NM_001100901

- UniProtKB:

B5DFL0 (UniProtKB/TrEMBL), F1MA17 (UniProtKB/TrEMBL), A0A8J8Y1B9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASGRRAPRTGLLELRSGAGSGAGGERWQRVLLTLAEDALTVSPADGEPGPEPEPAQLNGAAEP
GAASPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEALFVGDA
ILSVNGEDLSSATHDEAVQALKKTGKEVVLEVKYMKEVSPYFKNSAGGTSVGWDSPPASPLQRQ
PSSPGPQPRNLNEAKHVSLKMAYVSRRCTPTDPEPRYLEICAADGQDTLFLRAKDEASARSWAG
AIQAQISTFIPWVKDELQALLTATGTAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKELLLYCS
LPQTREALSRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELA
AWTRQLVDGCHRAAEGVQEVSTACTWNGRPCNLSVHIDKGFTLWAAEPGATRAVLLRQPFEKLQ
MSSDDGMSLLFLDFGGAEGEIQLDLHSCPKTMVFIIHSFLSAKVTRLGLLA

hide sequence

RefSeq Acc Id:	XP_006235388 ⟸ XM_006235326
- Peptide Label:	isoform X1
- UniProtKB:	A0A8J8Y1B9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASGRRAPRTGLLELRSGAGSGAGGERWQRVLLTLAEDALTVSPADGEPGPEPEPAQLNGAAEP GAASPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEALFVGDA ILSVNGEDLSSATHDEAVQALKKTGKEVVLEVKYMKEVSPYFKNSAGGTSVGWDSPPASPLQRQ PSSPGPQPRNLNEAKHVSLKMAYVSRRCTPTDPEPRYLEICAADGQDTLFLRAKDEASARSWAG AIQAQISTFIPWVKDELQALLTATGTAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKELLLYCS LPQTREALSRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELA AWTRQLVDGCHRAAEACTWNGRPCNLSVHIDKGFTLWAAEPGATRAVLLRQPFEKLQMSSDDGM SLLFLDFGGAEGEIQLDLHSCPKTMVFIIHSFLSAKVTRLGLLA hide sequence

RefSeq Acc Id:

ENSRNOP00000021715 ⟸ ENSRNOT00000021715

Protein Domains

PDZ PH

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B5DFL0-F1-model_v2	AlphaFold	B5DFL0	1-499	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692572

Promoter ID:

EPDNEW_R3097

Type:

initiation region

Name:

Snta1_1

Description:

syntrophin, alpha 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	149,905,921 - 149,905,981	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307068	AgrOrtholog
BioCyc Gene	G2FUF-47177	BioCyc
Ensembl Genes	ENSRNOG00000016062	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000021715	ENTREZGENE
	ENSRNOT00000021715.7	UniProtKB/TrEMBL
Gene3D-CATH	2.30.29.30	UniProtKB/TrEMBL
	2.30.42.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7370211	IMAGE-MGC_LOAD
InterPro	PDZ	UniProtKB/TrEMBL
	PDZ_sf	UniProtKB/TrEMBL
	PH_dom-like	UniProtKB/TrEMBL
	PHsplit_syntrophin	UniProtKB/TrEMBL
	Pleckstrin_homology	UniProtKB/TrEMBL
	Syntrophin	UniProtKB/TrEMBL
KEGG Report	rno:362242	UniProtKB/TrEMBL
MGC_CLONE	MGC:112776	IMAGE-MGC_LOAD
NCBI Gene	362242	ENTREZGENE
PANTHER	PTHR10554:SF6	UniProtKB/TrEMBL
	Syntrophin	UniProtKB/TrEMBL
Pfam	PDZ	UniProtKB/TrEMBL
	PF00169	UniProtKB/TrEMBL
	PH_17	UniProtKB/TrEMBL
PhenoGen	Snta1	PhenoGen
PROSITE	PDZ	UniProtKB/TrEMBL
	PH_DOMAIN	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000016062	RatGTEx
SMART	PDZ	UniProtKB/TrEMBL
	SM00233	UniProtKB/TrEMBL
Superfamily-SCOP	PDZ	UniProtKB/TrEMBL
	PH domain-like	UniProtKB/TrEMBL
UniProt	A0A8J8Y1B9	ENTREZGENE, UniProtKB/TrEMBL
	A6KHY5_RAT	UniProtKB/TrEMBL
	B5DFL0	ENTREZGENE, UniProtKB/TrEMBL
	F1MA17	ENTREZGENE
	Q498T0_RAT	UniProtKB/TrEMBL
UniProt Secondary	F1MA17	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-02-04	Snta1	syntrophin, alpha 1	Snta1	syntrophin, acidic 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Snta1	syntrophin, acidic 1	Snta1_predicted	syntrophin, acidic 1 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Snta1_predicted	syntrophin, acidic 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

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Imported Annotations - SMPDB