Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (S)-nicotine | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Nicotine results in increased expression of CCDC88A mRNA | CTD | PMID:17456735 | 1,3-dinitrobenzene | decreases expression | EXP | | 6480464 | 3-dinitrobenzene results in decreased expression of CCDC88A mRNA | CTD | PMID:21983209 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ccdc88a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CCDC88A promoter] | CTD | PMID:19654925 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CCDC88A mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CCDC88A mRNA | CTD | PMID:32109520 and PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CCDC88A mRNA | CTD | PMID:21570461 and PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of CCDC88A mRNA | CTD | PMID:22298810 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:26705709 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of CCDC88A mRNA | CTD | PMID:30047161 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of CCDC88A mRNA | CTD | PMID:36843608 | acrolein | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of CCDC88A mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of CCDC88A mRNA | CTD | PMID:32699268 | aflatoxin B1 | decreases methylation | ISO | CCDC88A (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of CCDC88A gene | CTD | PMID:27153756 | Aflatoxin B2 alpha | decreases methylation | ISO | CCDC88A (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of CCDC88A intron | CTD | PMID:30157460 | all-trans-retinoic acid | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of CCDC88A mRNA | CTD | PMID:21934132 | alpha-pinene | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of CCDC88A mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of CCDC88A mRNA | CTD | PMID:32699268 | benzo[a]pyrene | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of CCDC88A mRNA | CTD | PMID:20064835 | benzo[a]pyrene | affects methylation | ISO | CCDC88A (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of CCDC88A intron | CTD | PMID:30157460 | benzo[a]pyrene | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of CCDC88A mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of CCDC88A mRNA | CTD | PMID:19770486 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | bisphenol A results in increased expression of CCDC88A mRNA | CTD | PMID:27685785 | bisphenol A | decreases methylation | ISO | CCDC88A (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of CCDC88A gene | CTD | PMID:31601247 | bisphenol A | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CCDC88A gene | CTD | PMID:31601247 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CCDC88A mRNA | CTD | PMID:30816183 | cadmium atom | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Cadmium results in decreased expression of CCDC88A mRNA | CTD | PMID:21120746 | cadmium atom | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CCDC88A mRNA | CTD | PMID:35301059 | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of CCDC88A mRNA | CTD | PMID:33453195 | cadmium dichloride | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CCDC88A mRNA | CTD | PMID:35301059 | cadmium dichloride | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of CCDC88A mRNA | CTD | PMID:24982889 | caffeine | affects phosphorylation | ISO | CCDC88A (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of CCDC88A protein | CTD | PMID:35688186 | chlorpyrifos | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of CCDC88A mRNA | CTD | PMID:37019170 | cisplatin | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of CCDC88A mRNA | CTD | PMID:27392435 | clobetasol | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Clobetasol results in decreased expression of CCDC88A mRNA | CTD | PMID:27462272 | clofibrate | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Clofibrate results in increased expression of CCDC88A mRNA | CTD | PMID:17585979 | cocaine | increases expression | EXP | | 6480464 | Cocaine results in increased expression of CCDC88A mRNA | CTD | PMID:17898221 | copper(II) sulfate | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of CCDC88A mRNA | CTD | PMID:19549813 | crocidolite asbestos | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of CCDC88A mRNA | CTD | PMID:29279043 | dioxygen | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of CCDC88A mRNA | CTD | PMID:24205000 | dioxygen | affects methylation | ISO | Ccdc88a (Mus musculus) | 6480464 | Oxygen deficiency affects the methylation of CCDC88A promoter | CTD | PMID:24205000 | dorsomorphin | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of CCDC88A mRNA | CTD | PMID:29803840 | doxorubicin | multiple interactions | ISO | Ccdc88a (Mus musculus) | 6480464 | [Doxorubicin co-treated with Folic Acid] results in increased expression of CCDC88A mRNA | CTD | PMID:28608983 | enzyme inhibitor | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of CCDC88A protein | CTD | PMID:23301498 | ethanol | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Ethanol results in decreased expression of CCDC88A mRNA | CTD | PMID:29018328 | folic acid | multiple interactions | ISO | Ccdc88a (Mus musculus) | 6480464 | [Doxorubicin co-treated with Folic Acid] results in increased expression of CCDC88A mRNA | CTD | PMID:28608983 | formaldehyde | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of CCDC88A mRNA | CTD | PMID:20655997 and PMID:27664576 | fulvestrant | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CCDC88A gene | CTD | PMID:31601247 | hydrogen peroxide | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Hydrogen Peroxide results in increased expression of CCDC88A mRNA | CTD | PMID:18951874 | ivermectin | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of CCDC88A protein | CTD | PMID:32959892 | leflunomide | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | leflunomide results in decreased expression of CCDC88A mRNA | CTD | PMID:28988120 | maneb | multiple interactions | ISO | Ccdc88a (Mus musculus) | 6480464 | [Paraquat co-treated with Maneb] affects the expression of CCDC88A mRNA | CTD | PMID:22563483 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of CCDC88A mRNA | CTD | PMID:30047161 | miconazole | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Miconazole results in decreased expression of CCDC88A mRNA | CTD | PMID:27462272 | nicotine | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Nicotine results in increased expression of CCDC88A mRNA | CTD | PMID:17456735 | ozone | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of CCDC88A mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Acetaminophen affects the expression of CCDC88A mRNA | CTD | PMID:17562736 | paracetamol | affects expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Acetaminophen affects the expression of CCDC88A mRNA | CTD | PMID:25458485 | paraquat | multiple interactions | ISO | Ccdc88a (Mus musculus) | 6480464 | [Paraquat co-treated with Maneb] affects the expression of CCDC88A mRNA | CTD | PMID:22563483 | paraquat | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Paraquat results in increased expression of CCDC88A mRNA | CTD | PMID:22563483 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of CCDC88A mRNA | CTD | PMID:27153767 | phenylmercury acetate | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCDC88A mRNA | CTD | PMID:27188386 | pirinixic acid | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CCDC88A mRNA | CTD | PMID:19710929 | pyridaben | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | pyridaben results in increased expression of CCDC88A mRNA | CTD | PMID:22563483 | quercetin | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Quercetin results in decreased expression of CCDC88A mRNA | CTD | PMID:21632981 | quercetin | affects phosphorylation | ISO | CCDC88A (Homo sapiens) | 6480464 | Quercetin affects the phosphorylation of CCDC88A protein | CTD | PMID:35688186 | resveratrol | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of CCDC88A mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | serpentine asbestos | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Asbestos and Serpentine results in increased expression of CCDC88A mRNA | CTD | PMID:21148743 | sodium arsenate | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | sodium arsenate results in increased expression of CCDC88A mRNA | CTD | PMID:21795629 | sodium arsenite | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | sodium arsenite results in increased expression of CCDC88A mRNA | CTD | PMID:32068019 | succimer | multiple interactions | ISO | Ccdc88a (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of CCDC88A mRNA | CTD | PMID:21641980 | sunitinib | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of CCDC88A mRNA | CTD | PMID:31533062 | temozolomide | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of CCDC88A mRNA | CTD | PMID:31758290 | testosterone | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Testosterone results in decreased expression of CCDC88A mRNA | CTD | PMID:33359661 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of CCDC88A mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | titanium dioxide results in increased expression of CCDC88A mRNA | CTD | PMID:23557971 | toluene | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Toluene results in increased expression of CCDC88A mRNA | CTD | PMID:28245982 | torcetrapib | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | torcetrapib results in increased expression of CCDC88A mRNA | CTD | PMID:23228038 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of CCDC88A mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of CCDC88A mRNA | CTD | PMID:26272509 | trichostatin A | multiple interactions | ISO | CCDC88A (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCDC88A mRNA | CTD | PMID:27188386 | triptonide | decreases expression | ISO | Ccdc88a (Mus musculus) | 6480464 | triptonide results in decreased expression of CCDC88A mRNA | CTD | PMID:33045310 | valproic acid | decreases methylation | ISO | CCDC88A (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of CCDC88A gene | CTD | PMID:29154799 | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of CCDC88A mRNA | CTD | PMID:29427782 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of CCDC88A mRNA | CTD | PMID:29427782 | valproic acid | affects expression | ISO | Ccdc88a (Mus musculus) | 6480464 | Valproic Acid affects the expression of CCDC88A mRNA | CTD | PMID:17292431 | valproic acid | decreases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of CCDC88A mRNA | CTD | PMID:23179753 | valproic acid | increases expression | ISO | CCDC88A (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CCDC88A mRNA | CTD | PMID:29154799 | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of CCDC88A mRNA | CTD | PMID:19015723 | |