Sipa1l2 (signal-induced proliferation-associated 1 like 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Sipa1l2 (signal-induced proliferation-associated 1 like 2) Rattus norvegicus
Analyze
Symbol: Sipa1l2
Name: signal-induced proliferation-associated 1 like 2
RGD ID: 1306269
Description: Predicted to enable GTPase activator activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to be active in cytoplasm. Orthologous to human SIPA1L2 (signal induced proliferation associated 1 like 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC361442; serine-rich synapse associated protein 2; serine-rich synapse-associated protein; Sersap2; signal-induced proliferation-associated 1-like protein 2; SIPA1-like protein 2; Spar2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81970,287,134 - 70,437,810 (-)NCBIGRCr8
mRatBN7.21953,389,792 - 53,540,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1953,389,805 - 53,540,428 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1960,176,222 - 60,332,340 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01961,032,682 - 61,188,617 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01963,108,630 - 63,264,577 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01958,236,201 - 58,399,842 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1958,236,214 - 58,399,816 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01968,936,975 - 69,098,880 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41955,622,546 - 55,775,008 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11955,627,428 - 55,779,889 (-)NCBI
Celera1952,750,929 - 52,853,027 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP)
calcitriol  (ISO)
cantharidin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroacetaldehyde  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
clothianidin  (ISO)
cobalt dichloride  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
ifosfamide  (ISO)
isoflurane  (ISO)
leflunomide  (ISO)
manganese(II) chloride  (EXP)
mercury dibromide  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
propiconazole  (EXP)
SB 431542  (ISO)
sevoflurane  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
testosterone  (ISO)
tetraphene  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17961154   PMID:25931508   PMID:30706531  


Genomics

Comparative Map Data
Sipa1l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81970,287,134 - 70,437,810 (-)NCBIGRCr8
mRatBN7.21953,389,792 - 53,540,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1953,389,805 - 53,540,428 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1960,176,222 - 60,332,340 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01961,032,682 - 61,188,617 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01963,108,630 - 63,264,577 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01958,236,201 - 58,399,842 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1958,236,214 - 58,399,816 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01968,936,975 - 69,098,880 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41955,622,546 - 55,775,008 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11955,627,428 - 55,779,889 (-)NCBI
Celera1952,750,929 - 52,853,027 (-)NCBICelera
Cytogenetic Map19q12NCBI
SIPA1L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381232,397,965 - 232,630,496 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1232,397,965 - 232,630,571 (-)EnsemblGRCh38hg38GRCh38
GRCh371232,533,711 - 232,766,242 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361230,600,334 - 230,717,866 (-)NCBINCBI36Build 36hg18NCBI36
Celera1205,802,459 - 205,919,973 (-)NCBICelera
Cytogenetic Map1q42.2NCBI
HuRef1203,022,217 - 203,139,810 (-)NCBIHuRef
CHM1_11233,807,559 - 233,925,042 (-)NCBICHM1_1
T2T-CHM13v2.01231,783,662 - 232,016,327 (-)NCBIT2T-CHM13v2.0
Sipa1l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398126,144,807 - 126,296,602 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8126,144,802 - 126,296,547 (-)EnsemblGRCm39 Ensembl
GRCm388125,418,068 - 125,569,863 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8125,418,063 - 125,569,808 (-)EnsemblGRCm38mm10GRCm38
MGSCv378127,941,963 - 128,016,610 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368128,304,153 - 128,455,916 (-)NCBIMGSCv36mm8
Celera8129,732,717 - 129,807,059 (-)NCBICelera
Cytogenetic Map8E2NCBI
cM Map873.63NCBI
Sipa1l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554926,534,165 - 6,709,135 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554926,611,430 - 6,709,016 (+)NCBIChiLan1.0ChiLan1.0
SIPA1L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2116,575,631 - 16,810,753 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1116,771,642 - 17,006,582 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01207,944,776 - 208,180,227 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11212,966,017 - 213,177,329 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1212,966,023 - 213,101,179 (-)Ensemblpanpan1.1panPan2
SIPA1L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.147,024,936 - 7,238,268 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl47,071,645 - 7,237,090 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha47,012,971 - 7,226,332 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.047,047,657 - 7,261,112 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl47,047,336 - 7,260,591 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.147,057,294 - 7,269,791 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.047,176,930 - 7,390,556 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.047,401,471 - 7,614,980 (+)NCBIUU_Cfam_GSD_1.0
Sipa1l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934442,622,403 - 42,700,633 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648418,787,338 - 18,865,991 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648418,787,633 - 18,865,859 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SIPA1L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1458,117,570 - 58,352,504 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11458,116,906 - 58,352,507 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21462,424,381 - 62,588,239 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SIPA1L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12569,616,236 - 69,732,476 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2569,615,794 - 69,732,519 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605571,537,039 - 71,769,134 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sipa1l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477517,413,241 - 17,504,344 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477517,321,335 - 17,504,357 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sipa1l2
766 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:150
Count of miRNA genes:114
Interacting mature miRNAs:122
Transcripts:ENSRNOT00000026843
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)193383821455283146Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)194434021455283277Rat

Markers in Region
BF390033  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21953,509,315 - 53,509,455 (+)MAPPERmRatBN7.2
Rnor_6.01958,355,675 - 58,355,814NCBIRnor6.0
Rnor_5.01969,056,388 - 69,056,527UniSTSRnor5.0
RGSC_v3.41955,744,004 - 55,744,143UniSTSRGSC3.4
Celera1952,870,366 - 52,870,505UniSTS
RH 3.4 Map19736.1UniSTS
Cytogenetic Map19q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 40 12 4 5 4 74 22 33 11
Low 3 3 45 37 14 37 8 11 13 8 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000026843   ⟹   ENSRNOP00000026843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1953,389,805 - 53,540,428 (-)Ensembl
Rnor_6.0 Ensembl1958,236,214 - 58,399,816 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095461   ⟹   ENSRNOP00000084823
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1953,390,874 - 53,540,428 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096967   ⟹   ENSRNOP00000078337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1953,389,805 - 53,540,428 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112190   ⟹   ENSRNOP00000080159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1953,389,805 - 53,540,428 (-)Ensembl
RefSeq Acc Id: NM_001009704   ⟹   NP_001009704
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81970,287,147 - 70,437,773 (-)NCBI
mRatBN7.21953,389,805 - 53,540,428 (-)NCBI
Rnor_6.01958,236,214 - 58,399,816 (-)NCBI
Rnor_5.01968,936,975 - 69,098,880 (-)NCBI
RGSC_v3.41955,622,546 - 55,775,008 (-)RGD
Celera1952,750,929 - 52,853,027 (-)RGD
Sequence:
RefSeq Acc Id: XM_008772638   ⟹   XP_008770860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81970,287,134 - 70,437,810 (-)NCBI
mRatBN7.21953,389,792 - 53,540,466 (-)NCBI
Rnor_6.01958,236,201 - 58,399,842 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008772639   ⟹   XP_008770861
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81970,287,134 - 70,437,810 (-)NCBI
mRatBN7.21953,389,792 - 53,540,466 (-)NCBI
Rnor_6.01958,236,201 - 58,399,842 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097900   ⟹   XP_038953828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81970,287,134 - 70,437,810 (-)NCBI
mRatBN7.21953,389,792 - 53,540,466 (-)NCBI
RefSeq Acc Id: XM_039097901   ⟹   XP_038953829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81970,287,134 - 70,437,810 (-)NCBI
mRatBN7.21953,389,792 - 53,540,466 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001009704   ⟸   NM_001009704
- UniProtKB: Q5JCS6 (UniProtKB/Swiss-Prot),   F1M8G8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770861   ⟸   XM_008772639
- Peptide Label: isoform X4
- UniProtKB: Q5JCS6 (UniProtKB/Swiss-Prot),   A0A8I5ZPJ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770860   ⟸   XM_008772638
- Peptide Label: isoform X2
- UniProtKB: Q5JCS6 (UniProtKB/Swiss-Prot),   A0A8I6G2L5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000026843   ⟸   ENSRNOT00000026843
RefSeq Acc Id: XP_038953829   ⟸   XM_039097901
- Peptide Label: isoform X3
- UniProtKB: Q5JCS6 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038953828   ⟸   XM_039097900
- Peptide Label: isoform X1
- UniProtKB: Q5JCS6 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSRNOP00000078337   ⟸   ENSRNOT00000096967
RefSeq Acc Id: ENSRNOP00000084823   ⟸   ENSRNOT00000095461
RefSeq Acc Id: ENSRNOP00000080159   ⟸   ENSRNOT00000112190
Protein Domains
PDZ   Rap-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5JCS6-F1-model_v2 AlphaFold Q5JCS6 1-1722 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701248
Promoter ID:EPDNEW_R11771
Type:multiple initiation site
Name:Sipa1l2_1
Description:signal-induced proliferation-associated 1 like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01958,399,833 - 58,399,893EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306269 AgrOrtholog
BioCyc Gene G2FUF-5210 BioCyc
Ensembl Genes ENSRNOG00000019791 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026843 ENTREZGENE
  ENSRNOT00000026843.8 UniProtKB/TrEMBL
  ENSRNOT00000095461.1 UniProtKB/TrEMBL
  ENSRNOT00000096967.1 UniProtKB/TrEMBL
  ENSRNOT00000112190.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.11210 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.140.210 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rap/Ran-GAP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rap_GAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIPA1L_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:361442 UniProtKB/Swiss-Prot
NCBI Gene 361442 ENTREZGENE
PANTHER PTHR15711:SF7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAP GTPASE-ACTIVATING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rap-GAP_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rap_GAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPAR_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sipa1l2 PhenoGen
PROSITE PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAPGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019791 RatGTEx
SMART PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF111347 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZPJ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZY04_RAT UniProtKB/TrEMBL
  A0A8I6G2L5 ENTREZGENE, UniProtKB/TrEMBL
  F1M8G8 ENTREZGENE, UniProtKB/TrEMBL
  Q5JCS6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Sipa1l2  signal-induced proliferation-associated 1 like 2  Sipa1l2_predicted  signal-induced proliferation-associated 1 like 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sipa1l2_predicted  signal-induced proliferation-associated 1 like 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED