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Gene: Pak6 (p21 (RAC1) activated kinase 6) Rattus norvegicus
Analyze
Symbol:
Pak6
Name:
p21 (RAC1) activated kinase 6
RGD ID:
1306213
Description:
Predicted to have ATP binding activity; protein serine kinase activity; and protein threonine kinase activity. Predicted to be involved in learning or memory; locomotory behavior; and neuron projection morphogenesis. Predicted to localize to cell junction; fibrillar center; and nucleoplasm. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Orthologous to several human genes including BUB1B-PAK6 (BUB1B-PAK6 readthrough); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; T cell receptor signaling pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; acrylamide.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
LOC296078; p21 (CDKN1A)-activated kinase 6; p21 protein (Cdc42/Rac)-activated kinase 6; p21-activated kinase 6; serine/threonine-protein kinase PAK 6
RGD Orthologs
Alliance Genes
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
PAK6 (p21 (RAC1) activated kinase 6) HGNC
EggNOG, Ensembl, Inparanoid, NCBI, OrthoDB, Panther
Mus musculus (house mouse):
Pak6 (p21 (RAC1) activated kinase 6) HGNC
EggNOG, NCBI, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Pak6 (p21 (RAC1) activated kinase 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
PAK6 (p21 (RAC1) activated kinase 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
PAK6 (p21 (RAC1) activated kinase 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
LOC101957470 (serine/threonine-protein kinase PAK 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
PAK6 (p21 (RAC1) activated kinase 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
PAK6 (p21 (RAC1) activated kinase 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Pak6 (p21 (RAC1) activated kinase 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
BUB1B-PAK6 (BUB1B-PAK6 readthrough) HGNC
OMA, OrthoDB
Alliance orthologs 3
Homo sapiens (human):
PAK6 (p21 (RAC1) activated kinase 6)
Alliance
DIOPT (Ensembl Compara|HGNC|OMA|TreeFam)
Mus musculus (house mouse):
Pak6 (p21 (RAC1) activated kinase 6)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Homo sapiens (human):
BUB1B-PAK6 (BUB1B-PAK6 readthrough)
Alliance
DIOPT (Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Danio rerio (zebrafish):
pak6b (p21 protein (Cdc42/Rac)-activated kinase 6b)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Saccharomyces cerevisiae (baker's yeast):
CLA4
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER)
Drosophila melanogaster (fruit fly):
mbt
Alliance
DIOPT (Ensembl Compara|Hieranoid|PANTHER|PhylomeDB|TreeFam)
Caenorhabditis elegans (roundworm):
pak-2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|TreeFam)
Saccharomyces cerevisiae (baker's yeast):
SKM1
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER)
Saccharomyces cerevisiae (baker's yeast):
STE20
Alliance
DIOPT (Ensembl Compara|PANTHER|PhylomeDB)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl mRatBN7.2 3 105,638,248 - 105,674,399 (+) NCBI Rnor_6.0 Ensembl 3 110,442,637 - 110,487,526 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_6.0 3 110,442,175 - 110,486,317 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_5.0 3 116,987,226 - 117,027,426 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 105,141,150 - 105,191,676 (+) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 3 105,080,467 - 105,088,577 (+) NCBI Celera 3 104,554,473 - 104,587,411 (+) NCBI Celera Cytogenetic Map 3 q35 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Disease Annotations - ClinVar
Imported Disease Annotations - CTD
17beta-estradiol multiple interactions ISO RGD:1314703 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of PAK6 mRNA, Estradiol inhibits the reaction [ESR1 protein binds to PAK6 protein] CTD PMID:29389661 , PMID:30165855 2,2',5,5'-tetrachlorobiphenyl decreases expression EXP 6480464 2 more ... CTD PMID:23829299 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1314704 6480464 Tetrachlorodibenzodioxin affects the expression of PAK6 mRNA CTD PMID:21570461 3,4-methylenedioxymethamphetamine increases expression ISO RGD:1314704 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of PAK6 mRNA CTD PMID:20188158 , PMID:26251327 3-methylcholanthrene multiple interactions ISO RGD:1314704 6480464 [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PAK6 mRNA CTD PMID:23519560 4,4'-sulfonyldiphenol multiple interactions ISO RGD:1314703 6480464 bis4-hydroxyphenylsulfone inhibits the reaction [ESR1 protein binds to PAK6 protein] CTD PMID:29389661 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of PAK6 mRNA CTD PMID:24780913 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of PAK6 mRNA CTD PMID:28959563 afimoxifene decreases response to substance ISO RGD:1314703 6480464 PAK6 results in decreased susceptibility to afimoxifene CTD PMID:21233418 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of PAK6 mRNA CTD PMID:30779732 benzo[a]pyrene decreases expression ISO RGD:1314704 6480464 Benzoapyrene results in decreased expression of PAK6 mRNA CTD PMID:19770486 benzo[a]pyrene affects methylation ISO RGD:1314703 6480464 Benzoapyrene affects the methylation of PAK6 5' UTR CTD PMID:27901495 benzo[a]pyrene decreases methylation ISO RGD:1314703 6480464 Benzoapyrene results in decreased methylation of PAK6 exon CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:1314704 6480464 Benzoapyrene results in increased expression of PAK6 mRNA CTD PMID:23735875 benzo[e]pyrene increases methylation ISO RGD:1314703 6480464 benzoepyrene results in increased methylation of PAK6 3' UTR CTD PMID:30157460 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Testosterone] results in decreased expression of PAK6 mRNA CTD PMID:26496021 bisphenol A increases methylation ISO RGD:1314704 6480464 bisphenol A results in increased methylation of PAK6 promoter CTD PMID:27312807 bisphenol A multiple interactions ISO RGD:1314703 6480464 [bisphenol A binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to PAK6 protein modified form] CTD PMID:28751236 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PAK6 mRNA CTD PMID:25181051 , PMID:30816183 cadmium dichloride affects expression ISO RGD:1314704 6480464 Cadmium Chloride affects the expression of PAK6 mRNA CTD PMID:29408670 calcitriol decreases expression ISO RGD:1314703 6480464 Calcitriol results in decreased expression of PAK6 mRNA CTD PMID:16002434 carbon nanotube increases expression ISO RGD:1314704 6480464 Nanotubes more ... CTD PMID:25554681 cocaine decreases expression ISO RGD:1314703 6480464 Cocaine results in decreased expression of PAK6 mRNA CTD PMID:18000554 copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of PAK6 mRNA CTD PMID:26033743 copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of PAK6 mRNA CTD PMID:26033743 cyclosporin A decreases methylation ISO RGD:1314703 6480464 Cyclosporine results in decreased methylation of PAK6 promoter CTD PMID:27989131 dorsomorphin multiple interactions ISO RGD:1314703 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... CTD PMID:27188386 entinostat increases expression ISO RGD:1314703 6480464 entinostat results in increased expression of PAK6 mRNA CTD PMID:26272509 entinostat multiple interactions ISO RGD:1314703 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of PAK6 mRNA CTD PMID:27188386 finasteride decreases expression EXP 6480464 Finasteride results in decreased expression of PAK6 mRNA CTD PMID:24136188 indole-3-methanol multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PAK6 mRNA CTD PMID:22129741 lead(0) affects expression ISO RGD:1314703 6480464 Lead affects the expression of PAK6 mRNA CTD PMID:28903495 lead(2+) affects expression ISO RGD:1314703 6480464 Lead affects the expression of PAK6 mRNA CTD PMID:28903495 mercury dibromide multiple interactions ISO RGD:1314703 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of PAK6 mRNA CTD PMID:27188386 methapyrilene increases methylation ISO RGD:1314703 6480464 Methapyrilene results in increased methylation of PAK6 3' UTR CTD PMID:30157460 methotrexate increases expression ISO RGD:1314703 6480464 Methotrexate results in increased expression of PAK6 mRNA CTD PMID:21678067 N-acetyl-L-cysteine multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PAK6 mRNA CTD PMID:22129741 N-nitrosodiethylamine multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PAK6 mRNA CTD PMID:22129741 paracetamol affects expression ISO RGD:1314704 6480464 Acetaminophen affects the expression of PAK6 mRNA CTD PMID:17562736 PCB138 affects expression EXP 6480464 2 more ... CTD PMID:23829299 phenobarbital affects expression ISO RGD:1314704 6480464 Phenobarbital affects the expression of PAK6 mRNA CTD PMID:19136022 phenylmercury acetate increases expression ISO RGD:1314703 6480464 Phenylmercuric Acetate results in increased expression of PAK6 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1314703 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of PAK6 mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1314704 6480464 [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PAK6 mRNA CTD PMID:23519560 pirinixic acid affects expression ISO RGD:1314704 6480464 pirinixic acid affects the expression of PAK6 mRNA CTD PMID:19136022 pirinixic acid decreases expression ISO RGD:1314704 6480464 pirinixic acid results in decreased expression of PAK6 mRNA CTD PMID:23811191 potassium dichromate decreases expression ISO RGD:1314704 6480464 Potassium Dichromate results in decreased expression of PAK6 mRNA CTD PMID:23608068 SB 431542 multiple interactions ISO RGD:1314703 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... CTD PMID:27188386 sulindac decreases expression EXP 6480464 Sulindac results in decreased expression of PAK6 mRNA CTD PMID:24136188 sunitinib decreases expression ISO RGD:1314703 6480464 Sunitinib results in decreased expression of PAK6 mRNA CTD PMID:31533062 testosterone multiple interactions EXP 6480464 [bisphenol A co-treated with Testosterone] results in decreased expression of PAK6 mRNA CTD PMID:26496021 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of PAK6 mRNA CTD PMID:22659510 valproic acid affects expression ISO RGD:1314703 6480464 Valproic Acid affects the expression of PAK6 mRNA CTD PMID:25979313 valproic acid multiple interactions ISO RGD:1314703 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of PAK6 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:1314703 6480464 Valproic Acid results in increased expression of PAK6 mRNA CTD PMID:23179753 more ... valproic acid increases methylation ISO RGD:1314703 6480464 Valproic Acid results in increased methylation of PAK6 gene CTD PMID:29154799 vanadyl sulfate decreases expression ISO RGD:1314703 6480464 vanadyl sulfate results in decreased expression of PAK6 mRNA CTD PMID:16330358
Cellular Component
cell junction ISO RGD:1314703 1624291 RGD GO_REF:0000052 cell junction located_in ISO RGD:1314703 1624291 RGD GO_REF:0000052 cell junction located_in IEA UniProtKB:A0A024R9Q4 , ensembl:ENSP000004538581600115 GO_REF:0000107 Ensembl GO_REF:0000107 cell junction located_in IEA UniProtKB:Q9NQU5 , ensembl:ENSP000004538581600115 GO_REF:0000107 Ensembl GO_REF:0000107 cell junction IEA UniProtKB:Q9NQU5 , ensembl:ENSP000004538581600115 GO_REF:0000107 Ensembl GO_REF:0000107 cell junction IEA UniProtKB:A0A024R9Q4 , ensembl:ENSP000004538581600115 GO_REF:0000107 Ensembl GO_REF:0000107 cytoplasm IBA FB:FBgn0010909 more ... 13792537 PMID:21873635 GO_Central cytoplasm part_of IBA FB:FBgn0010909 more ... 13792537 PMID:21873635 GO_Central fibrillar center ISO RGD:1314703 1624291 RGD GO_REF:0000052 fibrillar center located_in IEA UniProtKB:A0A024R9Q4 , ensembl:ENSP000004538581600115 GO_REF:0000107 Ensembl GO_REF:0000107 fibrillar center located_in IEA UniProtKB:Q9NQU5 , ensembl:ENSP000004538581600115 GO_REF:0000107 Ensembl GO_REF:0000107 fibrillar center located_in ISO RGD:1314703 1624291 RGD GO_REF:0000052 fibrillar center IEA UniProtKB:Q9NQU5 , ensembl:ENSP000004538581600115 GO_REF:0000107 Ensembl GO_REF:0000107 fibrillar center IEA UniProtKB:A0A024R9Q4 , ensembl:ENSP000004538581600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleoplasm ISO RGD:1314703 1624291 RGD GO_REF:0000052 nucleoplasm located_in ISO RGD:1314703 1624291 RGD GO_REF:0000052 nucleoplasm located_in IEA UniProtKB:A0A024R9Q4 , ensembl:ENSP000004538581600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleoplasm located_in IEA UniProtKB:Q9NQU5 , ensembl:ENSP000004538581600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleoplasm IEA UniProtKB:A0A024R9Q4 , ensembl:ENSP000004538581600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleoplasm IEA UniProtKB:Q9NQU5 , ensembl:ENSP000004538581600115 GO_REF:0000107 Ensembl GO_REF:0000107
Imported Annotations - KEGG (archival)
References
Additional References at PubMed
Genomics
QTLs in Region (Rnor_6.0)
1358885 Bp251 Blood pressure QTL 251 3.8 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 10639528 127023997 Rat 1358888 Bp264 Blood pressure QTL 264 4.43 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 10639528 127023997 Rat 737818 Hcar12 Hepatocarcinoma resistance QTL 12 2.6 liver integrity trait (VT:0010547) volume of individual liver tumorous lesion (CMO:0001078) 3 30114912 123700444 Rat 70216 Cm14 Cardiac mass QTL 14 2.1 heart mass (VT:0007028) heart wet weight (CMO:0000069) 3 30846101 172879276 Rat 1358362 Srcrt2 Stress Responsive Cort QTL 2 2.78 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 3 39248391 140271184 Rat 2301970 Bw81 Body weight QTL 81 5.19 body mass (VT:0001259) body weight (CMO:0000012) 3 43295930 163640485 Rat 2301971 Cm71 Cardiac mass QTL 71 4.63 heart left ventricle mass (VT:0007031) heart left ventricle weight (CMO:0000776) 3 43295930 163640485 Rat 1581503 Cm58 Cardiac mass QTL 58 2.7 0.05 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 3 45406058 127023997 Rat 1559282 Emca5 Estrogen-induced mammary cancer QTL 5 3.9 mammary gland integrity trait (VT:0010552) percentage of study population developing mammary tumors during a period of time (CMO:0000948) 3 45406058 177699992 Rat 2292591 Esta4 Estrogen-induced thymic atrophy QTL 4 thymus mass (VT:0004954) thymus wet weight (CMO:0000855) 3 48561928 155263151 Rat 1358186 Ept2 Estrogen-induced pituitary tumorigenesis QTL 2 8.3 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 3 48562146 115249962 Rat 2292613 Ept16 Estrogen-induced pituitary tumorigenesis QTL 16 8.3 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 3 48562146 115249962 Rat 631665 Bw8 Body weight QTL 8 5.5 body mass (VT:0001259) body weight (CMO:0000012) 3 51821836 124513579 Rat 724523 Tsu1 Thymus enlargement suppressive QTL 1 3.84 thymus mass (VT:0004954) thymus weight to body weight ratio (CMO:0000612) 3 51822008 120917851 Rat 1582218 Bw74 Body weight QTL 74 3.9 0.0021 body mass (VT:0001259) body weight (CMO:0000012) 3 54630948 119830094 Rat 1582238 Bw68 Body weight QTL 68 3.2 0.0064 body mass (VT:0001259) body weight (CMO:0000012) 3 54630948 119830094 Rat 1582239 Epfw1 Epididymal fat weight QTL 1 4.5 0.0006 epididymal fat pad mass (VT:0010421) epididymal fat pad weight to body weight ratio (CMO:0000658) 3 54630948 119830094 Rat 1581568 Rf53 Renal function QTL 53 total urine protein amount (VT:0000032) urine protein excretion rate to body weight ratio (CMO:0001099) 3 58204463 170534769 Rat 8662816 Vetf4 Vascular elastic tissue fragility QTL 4 4 renal artery integrity trait (VT:0010642) number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563) 3 61241033 165369047 Rat 1300111 Rf12 Renal function QTL 12 3.78 renal blood flow trait (VT:2000006) absolute change in renal blood flow rate (CMO:0001168) 3 62922868 127023997 Rat 1582221 Kidm30 Kidney mass QTL 30 3.5 0.0008 kidney mass (VT:0002707) both kidneys wet weight (CMO:0000085) 3 66711607 119830094 Rat 1582210 Bw71 Body weight QTL 71 3.3 0.0012 body mass (VT:0001259) body weight (CMO:0000012) 3 66711607 119830094 Rat 12879848 Bw181 Body weght QTL 181 0.015 body mass (VT:0001259) body weight (CMO:0000012) 3 72672290 127023997 Rat 2301414 Kidm37 Kidney mass QTL 37 0.001 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 3 72973445 127023997 Rat 1600376 Arunc5 Aerobic running capacity QTL 5 0.21 exercise endurance trait (VT:0002332) maximum distance run on treadmill (CMO:0001406) 3 78700444 123700444 Rat 1581546 Pur13 Proteinuria QTL 13 2.93 0.0335 total urine protein amount (VT:0000032) urine protein excretion rate (CMO:0000759) 3 81136227 154416635 Rat 2302273 Gluco35 Glucose level QTL 35 5.3 0.001 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 3 83817637 119509260 Rat 7387306 Bw124 Body weight QTL 124 3.2 0.0003 body mass (VT:0001259) body weight (CMO:0000012) 3 88910015 133910015 Rat 631649 Bp123 Blood pressure QTL 123 3.2 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 94788365 139788365 Rat 8694437 Bw167 Body weight QTL 167 22.46 0.001 retroperitoneal fat pad mass (VT:0010430) retroperitoneal fat pad weight to body weight ratio (CMO:0000635) 3 97009185 142009185 Rat 631841 Niddm39 Non-insulin dependent diabetes mellitus QTL 39 3.36 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 3 99465522 168732722 Rat 1582219 Bw63 Body weight QTL 63 3.8 0.001 body mass (VT:0001259) body weight (CMO:0000012) 3 100730984 119830094 Rat 724532 Cm17 Cardiac mass QTL 17 2 heart mass (VT:0007028) calculated heart weight (CMO:0000073) 3 101058963 146058963 Rat 2293087 Iddm27 Insulin dependent diabetes mellitus QTL 27 2.68 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 3 102152812 155263151 Rat 1354611 Despr2 Despair related QTL 2 3.03 0.0028 locomotor behavior trait (VT:0001392) amount of time spent in voluntary immobility (CMO:0001043) 3 102466149 147466149 Rat 2312659 Slep7 Serum leptin concentration QTL 7 0.001 blood leptin amount (VT:0005667) serum leptin level (CMO:0000780) 3 103141814 176418101 Rat 2312670 Bw94 Body weight QTL 94 0.01 inguinal fat pad mass (VT:0010424) inguinal fat pad weight to body weight ratio (CMO:0001253) 3 103141814 176418101 Rat 2312673 Scl63 Serum cholesterol level QTL 63 0.001 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 3 103141814 176418101 Rat 2302373 Gluco39 Glucose level QTL 39 5.01 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 3 103141944 170934860 Rat 1582216 Bw65 Body weight QTL 65 6.3 body mass (VT:0001259) body weight (CMO:0000012) 3 106900427 119830094 Rat
