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Gene: Txndc12 (thioredoxin domain containing 12) Rattus norvegicus
Symbol: Txndc12
Name: thioredoxin domain containing 12
RGD ID: 1305960
Description: Predicted to have peptide disulfide oxidoreductase activity. Predicted to be involved in negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Predicted to localize to endoplasmic reticulum lumen. Orthologous to human TXNDC12 (thioredoxin domain containing 12); PARTICIPATES IN glutathione metabolic pathway; INTERACTS WITH bisphenol A; tetrachloromethane; vinclozolin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC298370; RGD1305960; similar to RIKEN cDNA 0610040B21; thioredoxin domain containing 12 (endoplasmic reticulum); thioredoxin domain-containing protein 12
Homo sapiens (human) : TXNDC12 (thioredoxin domain containing 12)  HGNC  Alliance
Mus musculus (house mouse) : Txndc12 (thioredoxin domain containing 12 (endoplasmic reticulum))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Txndc12 (thioredoxin domain containing 12)
Pan paniscus (bonobo/pygmy chimpanzee) : TXNDC12 (thioredoxin domain containing 12)
Canis lupus familiaris (dog) : TXNDC12 (thioredoxin domain containing 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Txndc12 (thioredoxin domain containing 12)
Sus scrofa (pig) : TXNDC12 (thioredoxin domain containing 12)
Chlorocebus sabaeus (African green monkey) : TXNDC12 (thioredoxin domain containing 12)
Heterocephalus glaber (naked mole-rat) : Txndc12 (thioredoxin domain containing 12)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05128,450,830 - 128,475,858 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5128,450,680 - 128,475,864 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05132,291,196 - 132,316,224 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45130,142,600 - 130,167,629 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15130,147,623 - 130,172,855 (+)NCBI
Celera5122,322,074 - 122,347,022 (+)NCBICelera
Cytogenetic Map5q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Txndc12
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305960
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.