Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | mitochondrial DNA depletion syndrome 13 | | ISO | FBXL4 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | mitochondrial DNA depletion syndrome 13 | | ISO | FBXL4 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
3. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
4. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Fbxl4 (Rattus norvegicus - Norway rat) |
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FBXL4 (Homo sapiens - human) |
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Fbxl4 (Mus musculus - house mouse) |
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Fbxl4 (Chinchilla lanigera - long-tailed chinchilla) |
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FBXL4 (Pan paniscus - bonobo/pygmy chimpanzee) |
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FBXL4 (Canis lupus familiaris - dog) |
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Fbxl4 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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FBXL4 (Sus scrofa - pig) |
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FBXL4 (Chlorocebus sabaeus - green monkey) |
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Fbxl4 (Heterocephalus glaber - naked mole-rat) |
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Variants in Fbxl4
497 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH129913 |
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RH129423 |
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RH131368 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 1 | 7 | 3 | 7 | 10 | 21 | 16 | 16 | 11 | 7 | |||
Low | 2 | 43 | 50 | 41 | 16 | 41 | 1 | 1 | 53 | 19 | 24 | 1 | |
Below cutoff | 1 |
RefSeq Transcripts | NM_001395576 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
NM_001395577 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
NR_172642 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017593342 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017593343 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039109815 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063287582 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063287583 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | BC161859 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
CH473962 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000005 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000061128 ⟹ ENSRNOP00000057843 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000077650 ⟹ ENSRNOP00000069859 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000102239 ⟹ ENSRNOP00000076415 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001395576 ⟹ NP_001382505 | ||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_001395577 ⟹ NP_001382506 | ||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NR_172642 | ||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||
Type: | NON-CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_017593342 ⟹ XP_017448831 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017593343 ⟹ XP_017448832 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039109815 ⟹ XP_038965743 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_063287582 ⟹ XP_063143652 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063287583 ⟹ XP_063143653 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001382505 | (Get FASTA) | NCBI Sequence Viewer |
NP_001382506 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017448831 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017448832 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038965743 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063143652 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063143653 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAI61859 | (Get FASTA) | NCBI Sequence Viewer |
EDL98529 | (Get FASTA) | NCBI Sequence Viewer | |
EDL98530 | (Get FASTA) | NCBI Sequence Viewer | |
EDL98531 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000057843 | ||
ENSRNOP00000057843.2 | |||
ENSRNOP00000069859.2 | |||
ENSRNOP00000076415 | |||
ENSRNOP00000076415.1 |
RefSeq Acc Id: | XP_017448831 ⟸ XM_017593342 |
- Peptide Label: | isoform X1 |
- UniProtKB: | B1WBR8 (UniProtKB/TrEMBL), F7FMX3 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017448832 ⟸ XM_017593343 |
- Peptide Label: | isoform X1 |
- UniProtKB: | B1WBR8 (UniProtKB/TrEMBL), F7FMX3 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000057843 ⟸ ENSRNOT00000061128 |
RefSeq Acc Id: | ENSRNOP00000069859 ⟸ ENSRNOT00000077650 |
RefSeq Acc Id: | XP_038965743 ⟸ XM_039109815 |
- Peptide Label: | isoform X1 |
- UniProtKB: | B1WBR8 (UniProtKB/TrEMBL), F7FMX3 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | ENSRNOP00000076415 ⟸ ENSRNOT00000102239 |
RefSeq Acc Id: | NP_001382505 ⟸ NM_001395576 |
- Peptide Label: | isoform 1 |
- UniProtKB: | B1WBR8 (UniProtKB/TrEMBL), F7FMX3 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | NP_001382506 ⟸ NM_001395577 |
- Peptide Label: | isoform 2 |
- UniProtKB: | A0A8I5Y8W0 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063143653 ⟸ XM_063287583 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_063143652 ⟸ XM_063287582 |
- Peptide Label: | isoform X2 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-B1WBR8-F1-model_v2 | AlphaFold | B1WBR8 | 1-621 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13693600 | ||||||||
Promoter ID: | EPDNEW_R4125 | ||||||||
Type: | initiation region | ||||||||
Name: | Fbxl4_1 | ||||||||
Description: | F-box and leucine-rich repeat protein 4 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1305724 | AgrOrtholog |
BioCyc Gene | G2FUF-41804 | BioCyc |
Ensembl Genes | ENSRNOG00000005641 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000061128 | ENTREZGENE |
ENSRNOT00000061128.5 | UniProtKB/TrEMBL | |
ENSRNOT00000077650.2 | UniProtKB/TrEMBL | |
ENSRNOT00000102239 | ENTREZGENE | |
ENSRNOT00000102239.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 1.20.1280.50 | UniProtKB/TrEMBL |
3.80.10.10 | UniProtKB/TrEMBL | |
IMAGE_CLONE | IMAGE:7096047 | IMAGE-MGC_LOAD |
InterPro | F-box_dom_cyclin-like | UniProtKB/TrEMBL |
F-box_dom_like | UniProtKB/TrEMBL | |
L_dom-like | UniProtKB/TrEMBL | |
Leu-rich_rpt_Cys-con_subtyp | UniProtKB/TrEMBL | |
MGC_CLONE | MGC:187392 | IMAGE-MGC_LOAD |
NCBI Gene | 313101 | ENTREZGENE |
PANTHER | F-BOX/LRR-REPEAT PROTEIN 4 | UniProtKB/TrEMBL |
UNCHARACTERIZED | UniProtKB/TrEMBL | |
Pfam | F-box-like | UniProtKB/TrEMBL |
PhenoGen | Fbxl4 | PhenoGen |
PROSITE | FBOX | UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000005641 | RatGTEx |
SMART | FBOX | UniProtKB/TrEMBL |
LRR_CC | UniProtKB/TrEMBL | |
Superfamily-SCOP | F-box_dom_Skp2-like | UniProtKB/TrEMBL |
RNI-like | UniProtKB/TrEMBL | |
UniProt | A0A0G2JWF5_RAT | UniProtKB/TrEMBL |
A0A8I5Y8W0 | ENTREZGENE, UniProtKB/TrEMBL | |
B1WBR8 | ENTREZGENE, UniProtKB/TrEMBL | |
F7FMX3 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2008-04-30 | Fbxl4 | F-box and leucine-rich repeat protein 4 | Fbxl4_predicted | F-box and leucine-rich repeat protein 4 (predicted) | 'predicted' is removed | 2292626 | APPROVED |
2005-01-12 | Fbxl4_predicted | F-box and leucine-rich repeat protein 4 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |