Fbxl4 (F-box and leucine-rich repeat protein 4) - Rat Genome Database

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Gene: Fbxl4 (F-box and leucine-rich repeat protein 4) Rattus norvegicus
Analyze
Symbol: Fbxl4
Name: F-box and leucine-rich repeat protein 4
RGD ID: 1305724
Description: Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in mitochondrial intermembrane space and nuclear speck. Predicted to be part of SCF ubiquitin ligase complex. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 13. Orthologous to human FBXL4 (F-box and leucine rich repeat protein 4); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: F-box/LRR-repeat protein 4; LOC313101
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8540,752,513 - 40,826,154 (+)NCBIGRCr8
mRatBN7.2535,955,801 - 36,029,446 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl535,955,812 - 36,029,443 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx538,081,930 - 38,155,709 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0539,674,526 - 39,748,301 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0539,614,187 - 39,687,968 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0536,555,061 - 36,628,920 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl536,555,109 - 36,629,689 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0541,196,912 - 41,270,903 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4537,156,876 - 37,230,228 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1537,157,055 - 37,230,404 (+)NCBI
Celera534,966,228 - 35,039,999 (+)NCBICelera
Cytogenetic Map5q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:19028597   PMID:23993194  


Genomics

Comparative Map Data
Fbxl4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8540,752,513 - 40,826,154 (+)NCBIGRCr8
mRatBN7.2535,955,801 - 36,029,446 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl535,955,812 - 36,029,443 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx538,081,930 - 38,155,709 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0539,674,526 - 39,748,301 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0539,614,187 - 39,687,968 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0536,555,061 - 36,628,920 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl536,555,109 - 36,629,689 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0541,196,912 - 41,270,903 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4537,156,876 - 37,230,228 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1537,157,055 - 37,230,404 (+)NCBI
Celera534,966,228 - 35,039,999 (+)NCBICelera
Cytogenetic Map5q21NCBI
FBXL4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38698,868,535 - 98,947,946 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl698,868,535 - 98,948,006 (-)EnsemblGRCh38hg38GRCh38
GRCh37699,316,411 - 99,395,822 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36699,428,322 - 99,502,570 (-)NCBINCBI36Build 36hg18NCBI36
Build 34699,428,321 - 99,502,570NCBI
Celera699,965,788 - 100,040,008 (-)NCBICelera
Cytogenetic Map6q16.1-q16.2NCBI
HuRef696,760,379 - 96,835,106 (-)NCBIHuRef
CHM1_1699,584,542 - 99,658,828 (-)NCBICHM1_1
T2T-CHM13v2.06100,042,904 - 100,122,314 (-)NCBIT2T-CHM13v2.0
Fbxl4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39422,357,526 - 22,434,091 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl422,357,543 - 22,434,091 (+)EnsemblGRCm39 Ensembl
GRCm38422,357,526 - 22,434,091 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl422,357,543 - 22,434,091 (+)EnsemblGRCm38mm10GRCm38
MGSCv37422,284,712 - 22,361,193 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36422,448,400 - 22,524,881 (+)NCBIMGSCv36mm8
Celera422,111,884 - 22,188,205 (+)NCBICelera
Cytogenetic Map4A3NCBI
cM Map49.69NCBI
Fbxl4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541124,757,445 - 24,814,643 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541124,757,445 - 24,814,642 (-)NCBIChiLan1.0ChiLan1.0
FBXL4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25118,922,871 - 118,996,545 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16116,801,917 - 116,877,758 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0696,717,103 - 96,790,932 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16100,599,381 - 100,661,249 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6100,599,390 - 100,661,249 (-)Ensemblpanpan1.1panPan2
FBXL4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11257,139,183 - 57,211,157 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1257,139,491 - 57,211,137 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1256,897,651 - 56,975,979 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01257,960,791 - 58,039,209 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1257,960,791 - 58,039,197 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11257,320,719 - 57,399,019 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01257,164,097 - 57,242,411 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01257,408,790 - 57,487,147 (-)NCBIUU_Cfam_GSD_1.0
Fbxl4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494692,074,873 - 92,153,958 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936651530,197 - 609,417 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936651530,296 - 609,443 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXL4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl165,872,123 - 65,935,703 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1165,872,119 - 65,936,442 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2174,422,380 - 74,485,593 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBXL4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11374,916,756 - 74,993,959 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1374,916,869 - 74,997,462 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604047,249,024 - 47,326,291 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxl4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248106,185,748 - 6,239,481 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248106,172,807 - 6,238,045 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fbxl4
497 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:174
Count of miRNA genes:139
Interacting mature miRNAs:163
Transcripts:ENSRNOT00000061128
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5384401847869213Rat
61462Niddm10Non-insulin dependent diabetes mellitus QTL 103.90.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)5511215947171491Rat
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)5894822853948228Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51268928557689285Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1549901Neudeg2Neurodegradation QTL 240nervous system integrity trait (VT:0010566)mononuclear cell count (CMO:0002119)52483871044045280Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat

Markers in Region
RH129913  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2536,029,121 - 36,029,334 (+)MAPPERmRatBN7.2
Rnor_6.0536,628,596 - 36,628,808NCBIRnor6.0
Rnor_5.0541,270,579 - 41,270,791UniSTSRnor5.0
RGSC_v3.4537,229,904 - 37,230,116UniSTSRGSC3.4
Celera535,039,675 - 35,039,887UniSTS
RH 3.4 Map5169.1UniSTS
Cytogenetic Map5q21UniSTS
RH129423  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2535,986,522 - 35,986,729 (+)MAPPERmRatBN7.2
Rnor_6.0536,585,997 - 36,586,203NCBIRnor6.0
Rnor_5.0541,227,830 - 41,228,036UniSTSRnor5.0
RGSC_v3.4537,187,609 - 37,187,815UniSTSRGSC3.4
Celera534,997,078 - 34,997,284UniSTS
RH 3.4 Map5181.8UniSTS
Cytogenetic Map5q21UniSTS
RH131368  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2535,954,379 - 35,954,563 (+)MAPPERmRatBN7.2
Rnor_6.0536,553,643 - 36,553,826NCBIRnor6.0
Rnor_5.0541,195,476 - 41,195,659UniSTSRnor5.0
RGSC_v3.4537,155,440 - 37,155,623UniSTSRGSC3.4
Celera534,964,792 - 34,964,975UniSTS
RH 3.4 Map5181.8UniSTS
Cytogenetic Map5q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 7 3 7 10 21 16 16 11 7
Low 2 43 50 41 16 41 1 1 53 19 24 1
Below cutoff 1

Sequence


RefSeq Acc Id: ENSRNOT00000061128   ⟹   ENSRNOP00000057843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl535,955,812 - 36,029,443 (+)Ensembl
Rnor_6.0 Ensembl536,555,109 - 36,628,917 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077650   ⟹   ENSRNOP00000069859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl535,955,812 - 36,024,469 (+)Ensembl
Rnor_6.0 Ensembl536,566,783 - 36,629,689 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102239   ⟹   ENSRNOP00000076415
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl535,955,828 - 36,029,441 (+)Ensembl
RefSeq Acc Id: NM_001395576   ⟹   NP_001382505
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,752,521 - 40,826,154 (+)NCBI
mRatBN7.2535,955,809 - 36,029,446 (+)NCBI
RefSeq Acc Id: NM_001395577   ⟹   NP_001382506
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,752,521 - 40,826,154 (+)NCBI
mRatBN7.2535,955,809 - 36,029,446 (+)NCBI
RefSeq Acc Id: NR_172642
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,752,521 - 40,826,154 (+)NCBI
mRatBN7.2535,955,809 - 36,029,446 (+)NCBI
RefSeq Acc Id: XM_017593342   ⟹   XP_017448831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,752,517 - 40,826,154 (+)NCBI
mRatBN7.2535,955,805 - 36,029,446 (+)NCBI
Rnor_6.0536,555,062 - 36,628,920 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593343   ⟹   XP_017448832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,752,513 - 40,826,154 (+)NCBI
mRatBN7.2535,955,801 - 36,029,446 (+)NCBI
Rnor_6.0536,555,062 - 36,628,920 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109815   ⟹   XP_038965743
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,752,517 - 40,826,154 (+)NCBI
mRatBN7.2535,955,805 - 36,029,446 (+)NCBI
RefSeq Acc Id: XM_063287582   ⟹   XP_063143652
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,752,517 - 40,826,154 (+)NCBI
RefSeq Acc Id: XM_063287583   ⟹   XP_063143653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,752,513 - 40,826,154 (+)NCBI
RefSeq Acc Id: XP_017448831   ⟸   XM_017593342
- Peptide Label: isoform X1
- UniProtKB: B1WBR8 (UniProtKB/TrEMBL),   F7FMX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448832   ⟸   XM_017593343
- Peptide Label: isoform X1
- UniProtKB: B1WBR8 (UniProtKB/TrEMBL),   F7FMX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000057843   ⟸   ENSRNOT00000061128
RefSeq Acc Id: ENSRNOP00000069859   ⟸   ENSRNOT00000077650
RefSeq Acc Id: XP_038965743   ⟸   XM_039109815
- Peptide Label: isoform X1
- UniProtKB: B1WBR8 (UniProtKB/TrEMBL),   F7FMX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000076415   ⟸   ENSRNOT00000102239
RefSeq Acc Id: NP_001382505   ⟸   NM_001395576
- Peptide Label: isoform 1
- UniProtKB: B1WBR8 (UniProtKB/TrEMBL),   F7FMX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001382506   ⟸   NM_001395577
- Peptide Label: isoform 2
- UniProtKB: A0A8I5Y8W0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143653   ⟸   XM_063287583
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063143652   ⟸   XM_063287582
- Peptide Label: isoform X2
Protein Domains
F-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1WBR8-F1-model_v2 AlphaFold B1WBR8 1-621 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693600
Promoter ID:EPDNEW_R4125
Type:initiation region
Name:Fbxl4_1
Description:F-box and leucine-rich repeat protein 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0536,555,102 - 36,555,162EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305724 AgrOrtholog
BioCyc Gene G2FUF-41804 BioCyc
Ensembl Genes ENSRNOG00000005641 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061128 ENTREZGENE
  ENSRNOT00000061128.5 UniProtKB/TrEMBL
  ENSRNOT00000077650.2 UniProtKB/TrEMBL
  ENSRNOT00000102239 ENTREZGENE
  ENSRNOT00000102239.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7096047 IMAGE-MGC_LOAD
InterPro F-box_dom_cyclin-like UniProtKB/TrEMBL
  F-box_dom_like UniProtKB/TrEMBL
  L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt_Cys-con_subtyp UniProtKB/TrEMBL
MGC_CLONE MGC:187392 IMAGE-MGC_LOAD
NCBI Gene 313101 ENTREZGENE
PANTHER F-BOX/LRR-REPEAT PROTEIN 4 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/TrEMBL
PhenoGen Fbxl4 PhenoGen
PROSITE FBOX UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005641 RatGTEx
SMART FBOX UniProtKB/TrEMBL
  LRR_CC UniProtKB/TrEMBL
Superfamily-SCOP F-box_dom_Skp2-like UniProtKB/TrEMBL
  RNI-like UniProtKB/TrEMBL
UniProt A0A0G2JWF5_RAT UniProtKB/TrEMBL
  A0A8I5Y8W0 ENTREZGENE, UniProtKB/TrEMBL
  B1WBR8 ENTREZGENE, UniProtKB/TrEMBL
  F7FMX3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Fbxl4  F-box and leucine-rich repeat protein 4   Fbxl4_predicted  F-box and leucine-rich repeat protein 4 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Fbxl4_predicted  F-box and leucine-rich repeat protein 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED