Wdr5 (WD repeat domain 5) - Rat Genome Database

Name: Wdr5
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Wdr5 (WD repeat domain 5) Rattus norvegicus

Analyze

Symbol:

Wdr5

Name:

WD repeat domain 5

RGD ID:

1305159

Description:

Predicted to enable histone H3K4 methyltransferase activity and methylated histone binding activity. Involved in neuron projection development. Predicted to be located in nucleoplasm. Predicted to be part of histone acetyltransferase complex and histone methyltransferase complex. Orthologous to human WDR5 (WD repeat domain 5); PARTICIPATES IN histone modification pathway; RNA polymerase II transcription initiation pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC100912075; LOC108348033; LOC362093; MGC114572; WD repeat-containing protein 5; WD repeat-containing protein 5-like

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	WDR5 (WD repeat domain 5)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, PhylomeDB, Treefam
Mus musculus (house mouse):	Wdr5 (WD repeat domain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Wdr5 (WD repeat domain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	WDR5 (WD repeat domain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	WDR5 (WD repeat domain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Wdr5 (WD repeat domain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	WDR5 (WD repeat domain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	WDR5 (WD repeat domain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Wdr5 (WD repeat domain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	WDR5B (WD repeat domain 5B)	HGNC	OrthoDB
Homo sapiens (human):	H2BC10 (H2B clustered histone 10)	HGNC	OMA
Homo sapiens (human):	H2BC5 (H2B clustered histone 5)	HGNC	OMA
Homo sapiens (human):	H2BC13 (H2B clustered histone 13)	HGNC	OMA
Homo sapiens (human):	H2BC9 (H2B clustered histone 9)	HGNC	OMA
Homo sapiens (human):	H2BC17 (H2B clustered histone 17)	HGNC	OMA
Homo sapiens (human):	H2BC21 (H2B clustered histone 21)	HGNC	OMA
Homo sapiens (human):	H2BC4 (H2B clustered histone 4)	HGNC	OMA
Homo sapiens (human):	H2BC8 (H2B clustered histone 8)	HGNC	OMA
Homo sapiens (human):	H2BC7 (H2B clustered histone 7)	HGNC	OMA
Homo sapiens (human):	H2BC6 (H2B clustered histone 6)	HGNC	OMA
Homo sapiens (human):	H2BC12 (H2B clustered histone 12)	HGNC	OMA
Homo sapiens (human):	H2BC18 (H2B clustered histone 18)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Wdr5 (WD repeat domain 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	WDR5 (WD repeat domain 5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	wdr5 (WD repeat domain 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SWD3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	wdr-5.3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	wdr-5.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	wds	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	wdr5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	10,836,964 - 10,856,682 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	10,837,025 - 10,856,671 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	13,905,180 - 13,924,115 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	22,490,606 - 22,509,541 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	20,745,229 - 20,764,191 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	6,061,892 - 6,080,724 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	6,061,940 - 6,080,680 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	11,422,748 - 11,441,574 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	6,432,879 - 6,451,846 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	6,432,099 - 6,450,947 (+)	NCBI
Celera	3	5,632,259 - 5,651,225 (+)	NCBI		Celera
Cytogenetic Map	3	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital heart disease (ISO)

developmental and epileptic encephalopathy 14 (ISO)

Ehlers-Danlos syndrome classic type 1 (ISO)

genetic disease (ISO)

Kleefstra syndrome 1 (ISO)

Leigh disease (ISO)

primary coenzyme Q10 deficiency 7 (ISO)

Rafiq syndrome (ISO)

tuberous sclerosis 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2-methylcholine (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

4-octylphenol (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

carnosic acid (ISO)

chlordecone (ISO)

clofibric acid (EXP)

decabromodiphenyl ether (ISO)

deoxynivalenol (ISO)

dicrotophos (ISO)

dioxygen (ISO)

diuron (EXP)

doxorubicin (ISO)

flutamide (EXP)

gadodiamide hydrate (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

ivermectin (ISO)

methidathion (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (EXP)

nickel atom (ISO)

Nonylphenol (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

sodium arsenite (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

trichloroethene (EXP)

trimellitic anhydride (ISO)

triticonazole (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

gluconeogenesis (IEA,ISO)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

neuron projection development (IDA)

obsolete regulation of dosage compensation by inactivation of X chromosome (IEA)

positive regulation of gluconeogenesis (IEA,ISO)

positive regulation of histone H3-K4 methylation (IEA,ISO)

regulation of cell cycle (IEA,ISO)

regulation of cell division (IEA,ISO)

regulation of DNA-templated transcription (ISO)

regulation of embryonic development (IEA,ISO)

regulation of transcription by RNA polymerase II (ISO)

regulation of tubulin deacetylation (IEA,ISO)

skeletal system development (IEA,ISO)

transcription initiation-coupled chromatin remodeling (IEA,ISO,ISS)

Cellular Component

ATAC complex (IEA,ISO)

histone acetyltransferase complex (ISO,ISS)

histone methyltransferase complex (ISO,ISS)

MLL1 complex (IEA,ISO,ISS)

MLL1/2 complex (ISO)

MLL3/4 complex (IEA,ISO)

NSL complex (IEA,ISO)

nucleoplasm (ISO)

nucleus (ISO,ISS)

Set1C/COMPASS complex (IBA,IEA,ISO,ISS)

Molecular Function

histone binding (IBA)

histone H3K4 methyltransferase activity (IEA,ISO)

methylated histone binding (IEA,ISO,ISS)

protein binding (IPI,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

histone modification pathway (ISO)

RNA polymerase II transcription initiation pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator.	Brown SA, etal., Science. 2005 Apr 29;308(5722):693-6.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	X-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expression.	Nakagawa T and Xiong Y, Mol Cell. 2011 Aug 5;43(3):381-91. doi: 10.1016/j.molcel.2011.05.033.
5.	Readout of epigenetic modifications.	Patel DJ and Wang Z, Annu Rev Biochem. 2013;82:81-118. doi: 10.1146/annurev-biochem-072711-165700.
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis.	Shilatifard A Annu Rev Biochem. 2012;81:65-95. doi: 10.1146/annurev-biochem-051710-134100.
8.	ATAC-king the complexity of SAGA during evolution.	Spedale G, etal., Genes Dev. 2012 Mar 15;26(6):527-41. doi: 10.1101/gad.184705.111.
9.	The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles.	Topalidou I, etal., PLoS Genet. 2016 May 18;12(5):e1006074. doi: 10.1371/journal.pgen.1006074. eCollection 2016 May.

Additional References at PubMed

PMID:11551928	PMID:12477932	PMID:15489334	PMID:15960975	PMID:16600877	PMID:17355966	PMID:17500065	PMID:17998332	PMID:18838386	PMID:18838538	PMID:18840606	PMID:19103755
PMID:19556245	PMID:20018852	PMID:20508642	PMID:22514746	PMID:24051374	PMID:26324722

Genomics

Comparative Map Data

Wdr5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	10,836,964 - 10,856,682 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	10,837,025 - 10,856,671 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	13,905,180 - 13,924,115 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	22,490,606 - 22,509,541 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	20,745,229 - 20,764,191 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	6,061,892 - 6,080,724 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	6,061,940 - 6,080,680 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	11,422,748 - 11,441,574 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	6,432,879 - 6,451,846 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	6,432,099 - 6,450,947 (+)	NCBI
Celera	3	5,632,259 - 5,651,225 (+)	NCBI		Celera
Cytogenetic Map	3	p12	NCBI

WDR5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	134,135,199 - 134,159,968 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	134,135,365 - 134,159,968 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	137,000,321 - 137,025,090 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	135,991,031 - 136,014,915 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	134,034,467 - 134,053,330	NCBI
Celera	9	107,546,368 - 107,570,384 (+)	NCBI		Celera
Cytogenetic Map	9	q34.2	NCBI
HuRef	9	106,494,213 - 106,518,092 (+)	NCBI		HuRef
CHM1_1	9	137,147,954 - 137,171,840 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	146,348,934 - 146,373,713 (+)	NCBI		T2T-CHM13v2.0

Wdr5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	27,405,159 - 27,426,547 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	27,405,169 - 27,426,547 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	27,515,147 - 27,536,535 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	27,515,157 - 27,536,535 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	27,370,667 - 27,392,055 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	27,337,223 - 27,358,544 (+)	NCBI		MGSCv36	mm8
Celera	2	27,217,888 - 27,239,293 (+)	NCBI		Celera
Cytogenetic Map	2	A3	NCBI
cM Map	2	19.38	NCBI

Wdr5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955513	3,198,980 - 3,216,468 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955513	3,198,655 - 3,213,754 (+)	NCBI	ChiLan1.0	ChiLan1.0

WDR5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	9	5,213,518 - 5,238,324 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	105,241,415 - 105,265,925 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	133,848,185 - 133,872,889 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	133,848,185 - 133,872,889 (+)	Ensembl	panpan1.1		panPan2

WDR5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	50,352,600 - 50,371,224 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	50,352,472 - 50,371,236 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	49,631,684 - 49,651,782 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	51,225,059 - 51,245,284 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	51,225,396 - 51,245,435 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	49,985,941 - 50,006,039 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	50,328,703 - 50,348,976 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	50,406,626 - 50,426,733 (+)	NCBI		UU_Cfam_GSD_1.0

Wdr5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	200,415,266 - 200,430,169 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936669	2,943,656 - 2,958,409 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936669	2,943,759 - 2,959,788 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

WDR5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	273,560,283 - 273,578,063 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	273,560,274 - 273,577,827 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	307,533,235 - 307,550,804 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

WDR5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	3,982,998 - 4,007,605 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	3,983,013 - 4,007,119 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666058	1,089,087 - 1,113,046 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Wdr5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	2,274,813 - 2,292,379 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	2,275,660 - 2,291,796 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Wdr5
25 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	207
Count of miRNA genes:	142
Interacting mature miRNAs:	171
Transcripts:	ENSRNOT00000011556
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70202	Alc19	Alcohol consumption QTL 19	2.5		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	3	1	27494778	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	1	31158234	Rat
631831	Alc8	Alcohol consumption QTL 8	2.7		consumption behavior trait (VT:0002069)	calculated ethanol drink intake rate (CMO:0001615)	3	1	33230976	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	diastolic blood pressure (CMO:0000005)	3	1	33278763	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	3	1	33278763	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	pulse pressure (CMO:0000292)	3	1	33278763	Rat
631545	Bp85	Blood pressure QTL 85	3.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	33278763	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	1	36847613	Rat
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	1	38710544	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	39874793	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	8227194	33703538	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	8227194	47233430	Rat
70203	Gcr2	Gastric cancer resistance QTL 2	2.6		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	3	8658162	27494778	Rat
1358357	Srcrtb1	Stress Responsive Cort Basal QTL 1	6.36	0.002	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	8658162	27494778	Rat
6893355	Bw101	Body weight QTL 101	0.4	0.38	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
6893363	Bw105	Body weight QTL 105	2.6	0.0036	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
1558654	Bw56	Body weight QTL 56	4.5	0.0000171	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
70191	BpQTLcluster4	Blood pressure QTL cluster 4	3		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	3	10778704	50302886	Rat
70191	BpQTLcluster4	Blood pressure QTL cluster 4	3		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	3	10778704	50302886	Rat
1558647	Cm46	Cardiac mass QTL 46	5.4	0.0000055	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	10778823	30356773	Rat
1558650	Cm48	Cardiac mass QTL 48	4	0.0001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	3	10778823	30356773	Rat
1558657	Cm43	Cardiac mass QTL 43	6.6	0.0000000293	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	10778823	30356773	Rat

Markers in Region

RH141408

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	10,856,268 - 10,856,455 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	6,080,311 - 6,080,497	NCBI	Rnor6.0
Rnor_5.0	3	11,441,161 - 11,441,347	UniSTS	Rnor5.0
RGSC_v3.4	3	6,451,451 - 6,451,637	UniSTS	RGSC3.4
Celera	3	5,650,830 - 5,651,016	UniSTS
RH 3.4 Map	3	10.7	UniSTS
Cytogenetic Map	3	p12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	32	41	26	19	26	1	1	73	30	41	11	1
Low		11	16	15		15	7	10	1	5			7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001039034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233831	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC100156	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000115	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000011556 ⟹ ENSRNOP00000011556

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	10,837,025 - 10,856,671 (+)	Ensembl
Rnor_6.0 Ensembl	3	6,061,940 - 6,080,680 (+)	Ensembl

RefSeq Acc Id:

NM_001039034 ⟹ NP_001034123

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	10,837,696 - 10,856,664 (+)	NCBI
Rnor_6.0	3	6,062,593 - 6,080,706 (+)	NCBI
Rnor_5.0	3	11,422,748 - 11,441,574 (+)	NCBI
RGSC_v3.4	3	6,432,879 - 6,451,846 (+)	RGD
Celera	3	5,632,259 - 5,651,225 (+)	RGD

Sequence:

show sequence

GGAATCTGCATTTGATTGGAGGGAGACTGATGGCTGCTGCCCTTCCATGATCACGTTCCCTGTA
GTGTAAAGCTGCGGTTGCCAGTTAACTGCCTCCTTTGTGGGCCGTGGAGGCCAGCTCCAAACCA
CCTGCTGAGGATCCTGCTTAACACACCTCCCTCCCAGAGCTGTCCTCTTCAAGTCCTGCTTTCC
GGTGACCTTAAAACAGAACACCTGAGTGCTCTCTGTCTTGGACTCTACCCAGTGGAATTGGAAA
TTGGTTTCCTTTGAGACGGTTTCAGGTCCCATAGAGTACGGGTTAGCTGACGGCTTCTTCCATT
GTGACTCCCTCTTCACGGTGTCCTGCCCTGTGGGCTTCAGAGCCATGGCCACGGAGGAGAAGAA
ACCAGAGACAGAGGCTGCAAGAGCACAGCCCACTCCTTCCTCATCAGCCACACAGAGCAAGCCT
ACACCTGTTAAGCCAAACTATGCCCTGAAGTTCACCCTGGCTGGCCACACAAAAGCTGTGTCCT
CTGTGAAGTTCAGCCCCAATGGGGAGTGGCTGGCAAGTTCCTCTGCTGATAAACTCATTAAAAT
TTGGGGAGCATATGATGGAAAGTTTGAGAAAACTATATCTGGTCACAAACTGGGAATATCTGAT
GTAGCCTGGTCATCAGATTCTAACCTCCTTGTGTCTGCCTCTGATGATAAAACTTTGAAGATTT
GGGACGTGAGTTCCGGAAAGTGTCTGAAGACCCTAAAGGGCCACAGTAACTATGTCTTCTGCTG
CAACTTCAACCCCCAGTCCAACCTCATCGTCTCAGGGTCTTTTGATGAAAGTGTGAGGATATGG
GATGTGAAGACAGGGAAGTGCCTCAAGACTTTGCCTGCCCATTCGGATCCAGTCTCAGCCGTTC
ATTTCAATCGTGATGGATCCTTGATCGTTTCCAGTAGCTATGATGGCCTCTGCCGAATCTGGGA
CACTGCCTCTGGCCAATGTCTGAAGACGCTCATTGATGACGACAATCCTCCGGTGTCCTTCGTG
AAGTTCTCTCCAAATGGCAAGTACATCCTGGCTGCAACTTTGGACAACACACTGAAGCTCTGGG
ACTACAGCAAAGGGAAGTGCCTGAAGACATACACCGGCCACAAGAATGAGAAGTACTGCATATT
TGCCAACTTCTCCGTGACAGGTGGGAAGTGGATCGTGTCTGGCTCTGAAGATAACCTGGTATAT
ATCTGGAATCTGCAGACCAAGGAGATCGTACAGAAGTTGCAGGGTCATACAGATGTCGTGATCT
CCACGGCCTGTCACCCAACAGAGAACATCATTGCCTCAGCAGCGTTAGAGAATGACAAAACAAT
CAAACTGTGGAAGAGTGACTGCTAAGCCCTGGCTCCATGGGAGACTTCAGGAAGCCACCCAGAT
TGGCAAGAAACACATGTGGGGCAGAGGCGTGGGGCCAGGTTGGGTTGACAGGCTTGGTGCACCT
CCTCTCTGAAGATGTCGGGCCAGGGGCGTGCATATATACCACCGAGTCTTGATAGCCACTGTGA
TATTTCTTGCCAATTCTGTCTCTGCCTGGGGAAGTTCCTGGTCTGTTCTGTGTGCTCAGAGGCA
ACAAATTTTTTAATTTTTTATTACAAGAGTGAGTCCAACTCCTCATGGGTTGTTTTTCTCTGTA
ATTGTTGTTTTGGTATTGTATTGCCCAGTGCACACACTGGAACAGGACCTACAGCCCTACTCCC
ATTCCCTGCCTCCAGCCTTGGCCTGCTTGTTCAAGTTCCCTACCTGTAATAGTACCCAGTGTGC
TTCCATGAGTTTCTGGAAACACAGAAAGGTTGTAAGTTGTATCTGTGTCAAGTCCCTTTGTTTT
TTTGGAGTTCATAGGTCAACACTGACCTCTCAGTGGTTGCAGTGTCCCCTTGTCTCACTGGTAT
CACTCAGTAAAGCCACACACTGTAATAAAAGGTGGGTATGGACTGGGTGTGGCCCTGAGTTCTG
ACAGAGCTCTTCACATCTGGGCTTTAGAACATACCCCCTCCCTGCAGGAGTTGGAAAAGTCTCT
GGGAGGTGGGTTCTGCTGGGCCTCCTCTTCCCAGTGGCTGTGTTGGCACTAAGTGTTTCGAGAG
GAAGAACCTCAGTTGAGAGAGTGGAAGGAAGGAAGTCTTGGAAAGGCACCATGTAGTGAGGTTC
TGGACCCTCTTTATCTCTGAATGAGGCTCAGGGTCACCTGTGCAGGAGGGAGAAGTTCAATTTG
GTGCTTGCCTCAGCAGATACAGCCTCCTGCCTTGGCCTCTGAATCCACCAAACCTCTCTTAGCC
CTTGCTCCAAATGGATCCTCAGGTGACCAGGCTAGAAAGAGATAATGGCCAAGCTAGAACTGCA
CAGCATTTTCACAACTGCTTCTGGCCAAACCCAGGTGGCCTGACACGAAGCAGACTGCAGAGGG
TCTGAGTCCAGATGGGTGGGCAAGGCTGCTGGGCACAGGCACAGGCAGAAAGGAGATTCTGGGT
TTGCTCTGGTTGTGGCAGCTTGCGAGGTCAATACTGATACGTATTGAAGCCAGGTTGCCCTGGT
CAGTAGCTGCTCTACTCTGCCTTTGCTGAGACCTGTCCCCAGCTGTGGTCCTCTTGGCCCTTCC
TCCGCTCCATCGTGGCACAATTAAGAATCCAAAGGTGTTGGAAAAGGACCCCCACACACATACA
TACCAGTACATTGTCTCTTCCTTGAGGGAGGTGATGTGCACATGGACTGTCACATTGAAGAAGC
CATTGTAATAGGGTGGCTTGTCACACTGACGTGGGTTCTGTGGCCCCTGGCATCTATGGGTAGA
TGTGCCTGGGTTCTGGTCAATGTTGTGGGCAGGTTGCTGGGGTTTCTGGAGGGGTGGTGAGGTC
TTTCCAGCTGTGGCCCGGTGTGCGGCCCCTCCTGAGGGAGGGAGCTTGCTTGCCATGTTGAGCG
CAGTATCCCCAAGTATAGTTTATTTTTTCTACAGTTGAACTCTGTTGTAGATTTATGTAAAAAT
ACATTCTCTTTTTAAAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAA

hide sequence

RefSeq Acc Id:

XM_006233831 ⟹ XP_006233893

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	10,836,964 - 10,856,682 (+)	NCBI
Rnor_6.0	3	6,061,892 - 6,080,724 (+)	NCBI
Rnor_5.0	3	11,422,748 - 11,441,574 (+)	NCBI

Sequence:

show sequence

ACGCGCAATCCCTCCCGCCTCCCGCGCCGCGGCCGACTGGTCCACCAGATCGTCTGCTCTCGCG
CGCAGGGCCAGCCGAGGCGACGCCAGAGCGCCCGGCCCCGCCGCCCCGGCCCCGGCAGTGTCTA
AGGCGGAAACAAGGAATCTGCATTTGATTGGAGGGAGACTGATGGCTGCTGCCCTTCCATGATC
ACGTTCCCTGTAGTGTAAAGCTGCGGTTGCCAGTTAACTGCCTCCTTTGTGGGCCGTGGAGGCC
AGCTCCAAACCACCTGCTGAGGATCCTGCTTAACACACCTCCCTCCCAGAGCTGTCCTCTTCAA
GTCCTGCTTTCCGGTGACCTTAAAACAGAACACCTGAGTGCTCTCTGTCTTGGACTCTACCCAG
TGGAATTGGAAATTGGTTTCCTTTGAGACGGTTTCAGGTCCCATAGAGTACGGGTTAGCTGACG
GCTTCTTCCATTGTGACTCCCTCTTCACGGTGTCCTGCCCTGTGGGCTTCAGAGCCATGGCCAC
GGAGGAGAAGAAACCAGAGACAGAGGCTGCAAGAGCACAGCCCACTCCTTCCTCATCAGCCACA
CAGAGCAAGCCTACACCTGTTAAGCCAAACTATGCCCTGAAGTTCACCCTGGCTGGCCACACAA
AAGCTGTGTCCTCTGTGAAGTTCAGCCCCAATGGGGAGTGGCTGGCAAGTTCCTCTGCTGATAA
ACTCATTAAAATTTGGGGAGCATATGATGGAAAGTTTGAGAAAACTATATCTGGTCACAAACTG
GGAATATCTGATGTAGCCTGGTCATCAGATTCTAACCTCCTTGTGTCTGCCTCTGATGATAAAA
CTTTGAAGATTTGGGACGTGAGTTCCGGAAAGTGTCTGAAGACCCTAAAGGGCCACAGTAACTA
TGTCTTCTGCTGCAACTTCAACCCCCAGTCCAACCTCATCGTCTCAGGGTCTTTTGATGAAAGT
GTGAGGATATGGGATGTGAAGACAGGGAAGTGCCTCAAGACTTTGCCTGCCCATTCGGATCCAG
TCTCAGCCGTTCATTTCAATCGTGATGGATCCTTGATCGTTTCCAGTAGCTATGATGGCCTCTG
CCGAATCTGGGACACTGCCTCTGGCCAATGTCTGAAGACGCTCATTGATGACGACAATCCTCCG
GTGTCCTTCGTGAAGTTCTCTCCAAATGGCAAGTACATCCTGGCTGCAACTTTGGACAACACAC
TGAAGCTCTGGGACTACAGCAAAGGGAAGTGCCTGAAGACATACACCGGCCACAAGAATGAGAA
GTACTGCATATTTGCCAACTTCTCCGTGACAGGTGGGAAGTGGATCGTGTCTGGCTCTGAAGAT
AACCTGGTATATATCTGGAATCTGCAGACCAAGGAGATCGTACAGAAGTTGCAGGGTCATACAG
ATGTCGTGATCTCCACGGCCTGTCACCCAACAGAGAACATCATTGCCTCAGCAGCGTTAGAGAA
TGACAAAACAATCAAACTGTGGAAGAGTGACTGCTAAGCCCTGGCTCCATGGGAGACTTCAGGA
AGCCACCCAGATTGGCAAGAAACACATGTGGGGCAGAGGCGTGGGGCCAGGTTGGGTTGACAGG
CTTGGTGCACCTCCTCTCTGAAGATGTCGGGCCAGGGGCGTGCATATATACCACCGAGTCTTGA
TAGCCACTGTGATATTTCTTGCCAATTCTGTCTCTGCCTGGGGAAGTTCCTGGTCTGTTCTGTG
TGCTCAGAGGCAACAAATTTTTTAATTTTTTATTACAAGAGTGAGTCCAACTCCTCATGGGTTG
TTTTTCTCTGTAATTGTTGTTTTGGTATTGTATTGCCCAGTGCACACACTGGAACAGGACCTAC
AGCCCTACTCCCATTCCCTGCCTCCAGCCTTGGCCTGCTTGTTCAAGTTCCCTACCTGTAATAG
TACCCAGTGTGCTTCCATGAGTTTCTGGAAACACAGAAAGGTTGTAAGTTGTATCTGTGTCAAG
TCCCTTTGTTTTTTTGGAGTTCATAGGTCAACACTGACCTCTCAGTGGTTGCAGTGTCCCCTTG
TCTCACTGGTATCACTCAGTAAAGCCACACACTGTAATAAAAGGTGGGTATGGACTGGGTGTGG
CCCTGAGTTCTGACAGAGCTCTTCACATCTGGGCTTTAGAACATACCCCCTCCCTGCAGGAGTT
GGAAAAGTCTCTGGGAGGTGGGTTCTGCTGGGCCTCCTCTTCCCAGTGGCTGTGTTGGCACTAA
GTGTTTCGAGAGGAAGAACCTCAGTTGAGAGAGTGGAAGGAAGGAAGTCTTGGAAAGGCACCAT
GTAGTGAGGTTCTGGACCCTCTTTATCTCTGAATGAGGCTCAGGGTCACCTGTGCAGGAGGGAG
AAGTTCAATTTGGTGCTTGCCTCAGCAGATACAGCCTCCTGCCTTGGCCTCTGAATCCACCAAA
CCTCTCTTAGCCCTTGCTCCAAATGGATCCTCAGGTGACCAGGCTAGAAAGAGATAATGGCCAA
GCTAGAACTGCACAGCATTTTCACAACTGCTTCTGGCCAAACCCAGGTGGCCTGACACGAAGCA
GACTGCAGAGGGTCTGAGTCCAGATGGGTGGGCAAGGCTGCTGGGCACAGGCACAGGCAGAAAG
GAGATTCTGGGTTTGCTCTGGTTGTGGCAGCTTGCGAGGTCAATACTGATACGTATTGAAGCCA
GGTTGCCCTGGTCAGTAGCTGCTCTACTCTGCCTTTGCTGAGACCTGTCCCCAGCTGTGGTCCT
CTTGGCCCTTCCTCCGCTCCATCGTGGCACAATTAAGAATCCAAAGGTGTTGGAAAAGGACCCC
CACACACATACATACCAGTACATTGTCTCTTCCTTGAGGGAGGTGATGTGCACATGGACTGTCA
CATTGAAGAAGCCATTGTAATAGGGTGGCTTGTCACACTGACGTGGGTTCTGTGGCCCCTGGCA
TCTATGGGTAGATGTGCCTGGGTTCTGGTCAATGTTGTGGGCAGGTTGCTGGGGTTTCTGGAGG
GGTGGTGAGGTCTTTCCAGCTGTGGCCCGGTGTGCGGCCCCTCCTGAGGGAGGGAGCTTGCTTG
CCATGTTGAGCGCAGTATCCCCAAGTATAGTTTATTTTTTCTACAGTTGAACTCTGTTGTAGAT
TTATGTAAAAATACATTCTCTTTTTAAAAATAAAGATTTTCATGTCTTGTAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001034123	(Get FASTA)	NCBI Sequence Viewer
	XP_006233893	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI00157	(Get FASTA)	NCBI Sequence Viewer
	EDL93432	(Get FASTA)	NCBI Sequence Viewer
	Q498M4	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001034123 ⟸ NM_001039034

- UniProtKB:

Q498M4 (UniProtKB/Swiss-Prot), A6JTL5 (UniProtKB/TrEMBL), A0A8L2Q668 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSS
ADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGH
SNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYD
GLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHK
NEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAA
LENDKTIKLWKSDC

hide sequence

RefSeq Acc Id:	XP_006233893 ⟸ XM_006233831
- Peptide Label:	isoform X1
- UniProtKB:	Q498M4 (UniProtKB/Swiss-Prot), A6JTL5 (UniProtKB/TrEMBL), A0A8L2Q668 (UniProtKB/TrEMBL)
- Sequence:	show sequence MATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSS ADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGH SNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYD GLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHK NEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAA LENDKTIKLWKSDC hide sequence

RefSeq Acc Id:

ENSRNOP00000011556 ⟸ ENSRNOT00000011556

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q498M4-F1-model_v2	AlphaFold	Q498M4	1-334	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305159	AgrOrtholog
BioCyc Gene	G2FUF-50294	BioCyc
Ensembl Genes	ENSRNOG00000008212	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000011556	ENTREZGENE
	ENSRNOP00000011556.4	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000011556	ENTREZGENE
	ENSRNOT00000011556.6	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7462311	IMAGE-MGC_LOAD
InterPro	G-protein_beta_WD-40_rep	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:362093	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:114572	IMAGE-MGC_LOAD
NCBI Gene	362093	ENTREZGENE
PANTHER	TRANSCRIPTION INITIATION FACTOR TFIID	UniProtKB/TrEMBL
	WD40 REPEAT PROTEIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD_REPEATS_REGION DOMAIN-CONTAINING PROTEIN	UniProtKB/Swiss-Prot
	WD_REPEATS_REGION DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
	WD_REPEATS_REGION DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
Pfam	WD40	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Wdr5	PhenoGen
PIRSF	GN-bd_beta	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	GPROTEINBRPT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	WD_REPEATS_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD_REPEATS_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD_REPEATS_REGION	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	WD40	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF50978	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8L2Q668	ENTREZGENE, UniProtKB/TrEMBL
	A6JTL5	ENTREZGENE, UniProtKB/TrEMBL
	Q498M4	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Wdr5	WD repeat domain 5	LOC108348033	WD repeat-containing protein 5-like	Data Merged	737654	PROVISIONAL
2016-08-02	LOC108348033	WD repeat-containing protein 5-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2015-07-29	Wdr5	WD repeat domain 5	LOC100912075	WD repeat-containing protein 5-like	Data Merged	737654	PROVISIONAL
2012-07-05	LOC100912075	WD repeat-containing protein 5-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-12-06	Wdr5	WD repeat domain 5	Wdr5_predicted	WD repeat domain 5 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Wdr5_predicted	WD repeat domain 5 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

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Imported Disease Annotations - ClinVar

RGD Manual Annotations