Iws1 (interacts with SUPT6H, CTD assembly factor 1) - Rat Genome Database

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Gene: Iws1 (interacts with SUPT6H, CTD assembly factor 1) Rattus norvegicus
Analyze
Symbol: Iws1
Name: interacts with SUPT6H, CTD assembly factor 1
RGD ID: 1304762
Description: Predicted to be involved in gene expression; regulation of mRNA export from nucleus; and regulation of mRNA processing. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human IWS1 (interacts with SUPT6H, CTD assembly factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: IWS1 homolog; IWS1 homolog (S. cerevisiae); IWS1, SUPT6H interacting protein; IWS1-like protein; LOC291705; MGC124986; protein IWS1 homolog; RGD1304762; similar to hypothetical protein FLJ10006
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81823,969,352 - 24,011,560 (+)NCBIGRCr8
mRatBN7.21823,695,496 - 23,737,363 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1823,695,425 - 23,736,172 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1823,823,597 - 23,861,406 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01824,579,583 - 24,617,407 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01823,918,579 - 23,956,389 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01824,849,508 - 24,891,339 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1824,849,545 - 24,880,317 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01824,564,090 - 24,606,101 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41824,489,571 - 24,524,125 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11824,494,575 - 24,550,538 (+)NCBI
Celera1823,448,049 - 23,478,821 (+)NCBICelera
Cytogenetic Map18p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:17234882   PMID:19141475  


Genomics

Comparative Map Data
Iws1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81823,969,352 - 24,011,560 (+)NCBIGRCr8
mRatBN7.21823,695,496 - 23,737,363 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1823,695,425 - 23,736,172 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1823,823,597 - 23,861,406 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01824,579,583 - 24,617,407 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01823,918,579 - 23,956,389 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01824,849,508 - 24,891,339 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1824,849,545 - 24,880,317 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01824,564,090 - 24,606,101 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41824,489,571 - 24,524,125 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11824,494,575 - 24,550,538 (+)NCBI
Celera1823,448,049 - 23,478,821 (+)NCBICelera
Cytogenetic Map18p12NCBI
IWS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382127,480,812 - 127,527,336 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2127,436,207 - 127,526,886 (-)EnsemblGRCh38hg38GRCh38
GRCh372128,238,388 - 128,284,065 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362127,954,860 - 128,000,514 (-)NCBINCBI36Build 36hg18NCBI36
Celera2121,549,354 - 121,595,041 (-)NCBICelera
Cytogenetic Map2q14.3NCBI
HuRef2120,545,348 - 120,591,062 (-)NCBIHuRef
CHM1_12128,242,935 - 128,288,602 (-)NCBICHM1_1
T2T-CHM13v2.02127,916,064 - 127,962,573 (-)NCBIT2T-CHM13v2.0
Iws1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391832,200,377 - 32,237,384 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1832,200,794 - 32,237,381 (+)EnsemblGRCm39 Ensembl
GRCm381832,067,326 - 32,104,331 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1832,067,741 - 32,104,328 (+)EnsemblGRCm38mm10GRCm38
MGSCv371832,227,388 - 32,263,985 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361832,210,774 - 32,240,318 (+)NCBIMGSCv36mm8
Celera1832,548,980 - 32,585,919 (+)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1817.92NCBI
Iws1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554593,021,764 - 3,063,128 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554593,021,320 - 3,063,363 (+)NCBIChiLan1.0ChiLan1.0
IWS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21348,118,820 - 48,221,507 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B48,133,798 - 48,200,382 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B32,750,718 - 32,810,360 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B128,132,447 - 128,192,258 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B128,146,087 - 128,192,258 (-)Ensemblpanpan1.1panPan2
IWS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11923,081,625 - 23,122,618 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1923,082,096 - 23,122,618 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1923,329,380 - 23,370,167 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01924,408,165 - 24,448,927 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1924,408,412 - 24,448,918 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11923,112,151 - 23,152,919 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01923,306,466 - 23,347,248 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01924,438,452 - 24,479,477 (+)NCBIUU_Cfam_GSD_1.0
Iws1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530397,813,621 - 97,851,019 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646943,766,663 - 43,808,333 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646943,766,699 - 43,805,919 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IWS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1559,822,822 - 59,879,422 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11559,822,789 - 59,875,867 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
IWS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1102,688,690 - 2,747,457 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl102,689,031 - 2,734,828 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606120,024,617 - 20,070,770 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Iws1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473213,966,393 - 14,001,713 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473213,961,929 - 14,002,003 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Iws1
85 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:314
Count of miRNA genes:197
Interacting mature miRNAs:226
Transcripts:ENSRNOT00000061011
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552968Pigfal19Plasma insulin-like growth factor 1 level QTL 1911.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)18125758124Rat
9590248Scort10Serum corticosterone level QTL 1019.710.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)18125758124Rat
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18130558703Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134291613Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134291613Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18142547119Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18518585840503530Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194179131393320Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181194179131393320Rat
12904690Cm129Cardiac mass QTL 1290.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)181194427326548295Rat
12904689Cm128Cardiac mass QTL 1280.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)181194427326548295Rat
12904693Am20Aortic mass QTL 200.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)181194427326548295Rat
12904695Kidm73Kidney mass QTL 730.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)181194427326548295Rat
12904691Cm130Cardiac mass QTL 1300.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)181194427326548295Rat
12904680Bw189Body weight QTL 1890.019body mass (VT:0001259)body weight (CMO:0000012)181194427326548295Rat
2301410Bp317Blood pressure QTL 3170.004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181194427326548295Rat
1331781Scl28Serum cholesterol level QTL 283.995blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)181194429924797117Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181194429931359530Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)181194429941122201Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181823456431359530Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181823456431359530Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat

Markers in Region
BF399129  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21823,710,093 - 23,710,313 (+)MAPPERmRatBN7.2
Rnor_6.01824,864,110 - 24,864,329NCBIRnor6.0
Rnor_5.01824,578,979 - 24,579,198UniSTSRnor5.0
RGSC_v3.41824,504,135 - 24,504,354UniSTSRGSC3.4
Celera1823,462,614 - 23,462,833UniSTS
RH 3.4 Map18315.5UniSTS
Cytogenetic Map18p12UniSTS
BE118002  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21823,726,103 - 23,726,244 (+)MAPPERmRatBN7.2
Rnor_6.01824,880,119 - 24,880,259NCBIRnor6.0
Rnor_5.01824,594,881 - 24,595,021UniSTSRnor5.0
RGSC_v3.41824,523,927 - 24,524,067UniSTSRGSC3.4
Celera1823,478,623 - 23,478,763UniSTS
RH 3.4 Map18314.3UniSTS
Cytogenetic Map18p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 44 28 19 28 8 10 74 35 41 11 8
Low 13 13 13 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000061011   ⟹   ENSRNOP00000057730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1823,695,527 - 23,726,302 (+)Ensembl
Rnor_6.0 Ensembl1824,849,545 - 24,880,317 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085516   ⟹   ENSRNOP00000069847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1823,695,425 - 23,726,276 (+)Ensembl
Rnor_6.0 Ensembl1824,849,553 - 24,880,282 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095752   ⟹   ENSRNOP00000090115
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1823,695,502 - 23,734,339 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102322   ⟹   ENSRNOP00000085053
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1823,695,502 - 23,720,740 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112252   ⟹   ENSRNOP00000091736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1823,695,502 - 23,736,172 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114318   ⟹   ENSRNOP00000095799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1823,695,771 - 23,726,276 (+)Ensembl
RefSeq Acc Id: NM_001034918   ⟹   NP_001030090
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81823,969,740 - 24,007,550 (+)NCBI
mRatBN7.21823,695,500 - 23,733,314 (+)NCBI
Rnor_6.01824,849,545 - 24,880,317 (+)NCBI
Rnor_5.01824,564,090 - 24,606,101 (+)NCBI
RGSC_v3.41824,489,571 - 24,524,125 (+)RGD
Celera1823,448,049 - 23,478,821 (+)RGD
Sequence:
RefSeq Acc Id: NM_001398635   ⟹   NP_001385564
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81823,969,740 - 24,007,550 (+)NCBI
mRatBN7.21823,695,500 - 23,733,314 (+)NCBI
RefSeq Acc Id: XM_006254572   ⟹   XP_006254634
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81823,969,352 - 24,000,237 (+)NCBI
mRatBN7.21823,695,496 - 23,726,005 (+)NCBI
Rnor_6.01824,849,508 - 24,880,115 (+)NCBI
Rnor_5.01824,564,090 - 24,606,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254573   ⟹   XP_006254635
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81823,969,352 - 24,007,550 (+)NCBI
mRatBN7.21823,695,496 - 23,726,299 (+)NCBI
Rnor_6.01824,849,508 - 24,880,314 (+)NCBI
Rnor_5.01824,564,090 - 24,606,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254574   ⟹   XP_006254636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81823,969,352 - 24,011,560 (+)NCBI
mRatBN7.21823,695,496 - 23,737,363 (+)NCBI
Rnor_6.01824,849,508 - 24,891,339 (+)NCBI
Rnor_5.01824,564,090 - 24,606,101 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600919   ⟹   XP_017456408
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81823,969,352 - 24,010,260 (+)NCBI
mRatBN7.21823,695,496 - 23,736,020 (+)NCBI
Rnor_6.01824,849,508 - 24,889,045 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063277254   ⟹   XP_063133324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81823,969,352 - 24,000,237 (+)NCBI
RefSeq Acc Id: XR_005496012
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81823,969,352 - 24,011,560 (+)NCBI
mRatBN7.21823,695,496 - 23,737,363 (+)NCBI
RefSeq Acc Id: XR_005496013
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81823,969,352 - 24,011,560 (+)NCBI
mRatBN7.21823,695,496 - 23,737,363 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001030090   ⟸   NM_001034918
- Peptide Label: isoform 1
- UniProtKB: Q3SWT4 (UniProtKB/Swiss-Prot),   A0A0G2JWE3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254634   ⟸   XM_006254572
- Peptide Label: isoform X2
- UniProtKB: Q3SWT4 (UniProtKB/Swiss-Prot),   A0A0G2JWE3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254636   ⟸   XM_006254574
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AF19 (UniProtKB/TrEMBL),   A0A8I6A2E0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254635   ⟸   XM_006254573
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JWE3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456408   ⟸   XM_017600919
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AB64 (UniProtKB/TrEMBL),   A0A8I6A2E0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000057730   ⟸   ENSRNOT00000061011
RefSeq Acc Id: ENSRNOP00000069847   ⟸   ENSRNOT00000085516
RefSeq Acc Id: ENSRNOP00000095799   ⟸   ENSRNOT00000114318
RefSeq Acc Id: ENSRNOP00000085053   ⟸   ENSRNOT00000102322
RefSeq Acc Id: ENSRNOP00000091736   ⟸   ENSRNOT00000112252
RefSeq Acc Id: ENSRNOP00000090115   ⟸   ENSRNOT00000095752
RefSeq Acc Id: NP_001385564   ⟸   NM_001398635
- Peptide Label: isoform 2
RefSeq Acc Id: XP_063133324   ⟸   XM_063277254
- Peptide Label: isoform X3
Protein Domains
TFIIS N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3SWT4-F1-model_v2 AlphaFold Q3SWT4 1-764 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700686
Promoter ID:EPDNEW_R11205
Type:initiation region
Name:Iws1_1
Description:IWS1, SUPT6H interacting protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01824,849,554 - 24,849,614EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304762 AgrOrtholog
BioCyc Gene G2FUF-8044 BioCyc
Ensembl Genes ENSRNOG00000014630 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055025752 UniProtKB/Swiss-Prot
  ENSRNOG00060028060 UniProtKB/Swiss-Prot
  ENSRNOG00065012356 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000061011 ENTREZGENE
  ENSRNOT00000061011.4 UniProtKB/Swiss-Prot
  ENSRNOT00000085516.2 UniProtKB/TrEMBL
  ENSRNOT00000095752.1 UniProtKB/TrEMBL
  ENSRNOT00000102322.1 UniProtKB/TrEMBL
  ENSRNOT00000112252.1 UniProtKB/TrEMBL
  ENSRNOT00000114318.1 UniProtKB/TrEMBL
  ENSRNOT00055044462 UniProtKB/Swiss-Prot
  ENSRNOT00060048817 UniProtKB/Swiss-Prot
  ENSRNOT00065020129 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.930.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7190021 IMAGE-MGC_LOAD
InterPro TFIIS/LEDGF_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TFIIS_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:291705 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124986 IMAGE-MGC_LOAD
NCBI Gene 291705 ENTREZGENE
PANTHER PROTEIN IWS1 HOMOLOG UniProtKB/Swiss-Prot
  PROTEIN IWS1 HOMOLOG UniProtKB/Swiss-Prot
  PROTEIN IWS1 HOMOLOG UniProtKB/TrEMBL
  PROTEIN IWS1 HOMOLOG UniProtKB/TrEMBL
Pfam Med26 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Iws1 PhenoGen
PROSITE TFIIS_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014630 RatGTEx
  ENSRNOG00055025752 RatGTEx
  ENSRNOG00060028060 RatGTEx
  ENSRNOG00065012356 RatGTEx
Superfamily-SCOP SSF47676 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JWE3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A2E0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AB64 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AF19 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AQ12_RAT UniProtKB/TrEMBL
  IWS1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-10 Iws1  interacts with SUPT6H, CTD assembly factor 1  Iws1  IWS1, SUPT6H interacting protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-13 Iws1  IWS1, SUPT6H interacting protein  Iws1  IWS1 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-06-15 Iws1  IWS1 homolog (S. cerevisiae)  RGD1304762  similar to hypothetical protein FLJ10006  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1304762  similar to hypothetical protein FLJ10006  RGD1304762_predicted  similar to hypothetical protein FLJ10006 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1304762_predicted  similar to hypothetical protein FLJ10006 (predicted)  LOC291705_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC291705_predicted  similar to hypothetical protein FLJ10006 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL