Actg1 (actin, gamma 1) - Rat Genome Database

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Gene: Actg1 (actin, gamma 1) Rattus norvegicus
Analyze
Symbol: Actg1
Name: actin, gamma 1
RGD ID: 1304556
Description: A structural constituent of postsynaptic actin cytoskeleton. Involved in response to calcium ion and response to mechanical stimulus. Localizes to postsynaptic actin cytoskeleton and presynaptic actin cytoskeleton. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome and autosomal dominant nonsyndromic deafness 20. Orthologous to human ACTG1 (actin gamma 1); PARTICIPATES IN auditory mechanotransduction pathway; arrhythmogenic right ventricular cardiomyopathy pathway; dilated cardiomyopathy pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Actg; actin, cytoplasmic 2; actin, gamma, cytoplasmic; actin, gamma, cytoplasmic 1; gamma-actin; LOC287876
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.210105,619,738 - 105,622,587 (-)NCBI
Rnor_6.0 Ensembl10109,519,134 - 109,520,846 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl375,643,054 - 75,644,954 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.010109,518,429 - 109,521,288 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010109,113,705 - 109,116,103 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410109,773,489 - 109,776,334 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110109,787,992 - 109,790,826 (-)NCBI
Celera10104,164,981 - 104,167,826 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3,3'-diindolylmethane  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amphetamine  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bufalin  (ISO)
buspirone  (EXP)
carbon nanotube  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cytochalasin D  (ISO)
D-glucose  (EXP)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
dihydroartemisinin  (ISO)
dioxygen  (EXP)
dopamine  (EXP)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
fenoldopam  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fumonisin B1  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glucose  (EXP)
GW 4064  (ISO)
jaspamide  (ISO)
leflunomide  (ISO)
levofloxacin  (EXP)
mancozeb  (ISO)
metacetamol  (ISO)
methamphetamine  (EXP)
methotrexate  (ISO)
microcystin  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosomorpholine  (EXP)
ozone  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorododecanoic acid  (EXP)
phenformin  (EXP)
phenobarbital  (EXP)
PhIP  (EXP)
pirinixic acid  (ISO)
potassium dichromate  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
rac-lactic acid  (ISO)
rotenone  (EXP)
Salinomycin  (ISO)
selenium atom  (ISO)
sodium fluoride  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
yohimbine  (EXP)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

References

Additional References at PubMed
PMID:2372296   PMID:2402472   PMID:9334353   PMID:12063253   PMID:12947022   PMID:14760703   PMID:15194427   PMID:16189514   PMID:16502470   PMID:16510873   PMID:17634366   PMID:18796539  
PMID:19013151   PMID:19144319   PMID:19946888   PMID:20458337   PMID:21516116   PMID:21557262   PMID:21630459   PMID:21753002   PMID:22516433   PMID:22855531   PMID:23376485   PMID:23382103  
PMID:23533145   PMID:23580065   PMID:23979707   PMID:25416956   PMID:25705373   PMID:25910212   PMID:27840001   PMID:28259758   PMID:28493397   PMID:29891944  


Genomics

Comparative Map Data
Actg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.210105,619,738 - 105,622,587 (-)NCBI
Rnor_6.0 Ensembl10109,519,134 - 109,520,846 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl375,643,054 - 75,644,954 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.010109,518,429 - 109,521,288 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010109,113,705 - 109,116,103 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410109,773,489 - 109,776,334 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110109,787,992 - 109,790,826 (-)NCBI
Celera10104,164,981 - 104,167,826 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
ACTG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1781,509,413 - 81,523,847 (-)EnsemblGRCh38hg38GRCh38
GRCh381781,509,971 - 81,512,799 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371779,476,997 - 79,479,825 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,091,594 - 77,094,422 (-)NCBINCBI36hg18NCBI36
Build 341777,091,593 - 77,094,422NCBI
Cytogenetic Map17q25.3NCBI
HuRef1774,925,813 - 74,928,708 (-)NCBIHuRef
CHM1_11779,563,278 - 79,566,173 (-)NCBICHM1_1
Actg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,236,513 - 120,239,321 (-)NCBIGRCm39mm39
GRCm39 Ensembl11120,236,516 - 120,239,368 (-)Ensembl
GRCm3811120,345,687 - 120,348,495 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,345,690 - 120,348,542 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,207,004 - 120,209,798 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611120,161,780 - 120,171,339 (-)NCBImm8
Celera11132,080,255 - 132,083,049 (-)NCBICelera
Cytogenetic Map11E2NCBI
Actg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555061,546,678 - 1,552,105 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555061,546,678 - 1,549,611 (+)NCBIChiLan1.0ChiLan1.0
ACTG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11781,668,221 - 81,671,087 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1781,668,221 - 81,671,087 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01775,965,911 - 75,968,822 (-)NCBIMhudiblu_PPA_v0panPan3
ACTG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.19635,978 - 638,328 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl9635,978 - 638,328 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha91,238,649 - 1,241,000 (+)NCBI
ROS_Cfam_1.091,229,608 - 1,232,436 (+)NCBI
UMICH_Zoey_3.191,254,519 - 1,256,870 (+)NCBI
UNSW_CanFamBas_1.091,380,335 - 1,382,686 (+)NCBI
UU_Cfam_GSD_1.091,460,286 - 1,462,637 (+)NCBI
Actg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056021,238,788 - 1,241,248 (+)NCBI
SpeTri2.0NW_0049365945,170,711 - 5,173,251 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACTG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl121,160,350 - 1,323,217 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1121,320,355 - 1,323,219 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2121,163,186 - 1,166,032 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACTG1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,456,907 - 73,459,777 (-)NCBI
Vero_WHO_p1.0NW_02366607744,839,199 - 44,842,119 (-)NCBI
Actg1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480110,496,876 - 10,499,737 (-)NCBI

Position Markers
PMC138261P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p11UniSTS
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map18p12UniSTS
PMC156330P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera1951,258,498 - 51,259,502UniSTS
Celera1213,454,501 - 13,455,354UniSTS
Cytogenetic Map12p11UniSTS
Cytogenetic Map18p12UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map10q32.3UniSTS
PMC201106P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p11UniSTS
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map18p12UniSTS
PMC22644P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p11UniSTS
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map18p12UniSTS
PMC302066P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p11UniSTS
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map18p12UniSTS
PMC97568P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p11UniSTS
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map18p12UniSTS
RH128697  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map18p12UniSTS
PMC156124P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p11UniSTS
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map18p12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014827894110992275Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1023861015112626471Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1053621375112626471Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1053621375112626471Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1055678976112626471Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1065590122110590122Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1065992275110992275Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1065992275110992275Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1067880046112626471Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1067988218110992091Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1069385595112626471Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1069385595112626471Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1070166960112626471Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1070800069112626471Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1071692298112626471Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1073008136112626471Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1073008136112626471Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1073008136112626471Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1073467158112626471Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1075544754112626471Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1075544754112626471Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1078970279112626471Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1079927661112626471Rat
4889492Pancm2Pancreatic morphology QTL 23.2pancreatic beta cell morphology trait (VT:0005217)ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)1080239190112626471Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1085079943112626471Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)1086566908112626471Rat
631538Oia5Oil induced arthritis QTL 5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1090041957112626471Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1090296897112626471Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1091689348112626471Rat
1579915Bp280Blood pressure QTL 2800.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1093662786112626471Rat
12880395Cm109Cardiac mass QTL 1090.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1093662786112626471Rat
12880396Am13Aortic mass QTL 130.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1093662786112626471Rat
12880398Kidm67Kidney mass QTL 670.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1093662786112626471Rat
12880384Cm107Cardiac mass QTL 1070.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)93662786112626471Rat
12880385Cm108Cardiac mass QTL 1080.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)93662786112626471Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1093886117110992275Rat
724530Bp149Blood pressure QTL 1490.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1093886117112626471Rat
1558652Bw57Body weight QTL 574.20.0008body mass (VT:0001259)body weight (CMO:0000012)1094170766112626471Rat
1354641Bvd2Brain ventricular dilatation QTL 26.360.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)1096520816110992275Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1098079221112626471Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1098079221112626471Rat
1578663Bss18Bone structure and strength QTL 183.6femur width (VT:1000666)femoral neck width (CMO:0001695)10100155035110992275Rat
1578672Bmd16Bone mineral density QTL 166.2femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)10100155035110992275Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:104
Count of miRNA genes:79
Interacting mature miRNAs:91
Transcripts:ENSRNOT00000054976
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 9 8 8 8 102 18 29 2
Medium 2 86 106 74 38 74 16 22 46 52 53 20 16
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001127449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CF110974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK364554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK595239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000054976   ⟹   ENSRNOP00000051859
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl10109,519,134 - 109,520,846 (-)Ensembl
RefSeq Acc Id: NM_001127449   ⟹   NP_001120921
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.210105,619,742 - 105,622,587 (-)NCBI
Rnor_6.010109,518,433 - 109,521,288 (-)NCBI
Rnor_5.010109,113,705 - 109,116,103 (-)NCBI
RGSC_v3.410109,773,489 - 109,776,334 (-)RGD
Celera10104,164,981 - 104,167,826 (-)RGD
Sequence:
RefSeq Acc Id: XM_017597166   ⟹   XP_017452655
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.010109,518,429 - 109,520,871 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597167   ⟹   XP_017452656
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.010109,518,429 - 109,520,852 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039085690   ⟹   XP_038941618
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.210105,619,738 - 105,622,582 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001120921 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941618 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM06825 (Get FASTA)   NCBI Sequence Viewer  
  P63259 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001120921   ⟸   NM_001127449
- UniProtKB: P63259 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017452655   ⟸   XM_017597166
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017452656   ⟸   XM_017597167
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000051859   ⟸   ENSRNOT00000054976
RefSeq Acc Id: XP_038941618   ⟸   XM_039085690
- Peptide Label: isoform X1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304556 AgrOrtholog
Ensembl Genes ENSRNOG00000036701 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000053452 Ensembl, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000051859 UniProtKB/Swiss-Prot
  ENSRNOP00000072273 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000054976 UniProtKB/Swiss-Prot
  ENSRNOT00000079310 UniProtKB/Swiss-Prot
InterPro Actin UniProtKB/Swiss-Prot
  Actin/actin-like_CS UniProtKB/Swiss-Prot
  Actin_CS UniProtKB/Swiss-Prot
  ATPase_NBD UniProtKB/Swiss-Prot
KEGG Report rno:100361457 UniProtKB/Swiss-Prot
  rno:287876 UniProtKB/Swiss-Prot
NCBI Gene 287876 ENTREZGENE
PANTHER PTHR11937 UniProtKB/Swiss-Prot
Pfam Actin UniProtKB/Swiss-Prot
PhenoGen Actg1 PhenoGen
PRINTS ACTIN UniProtKB/Swiss-Prot
PROSITE ACTINS_1 UniProtKB/Swiss-Prot
  ACTINS_2 UniProtKB/Swiss-Prot
  ACTINS_ACT_LIKE UniProtKB/Swiss-Prot
SMART ACTIN UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53067 UniProtKB/Swiss-Prot
UniProt ACTG_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P02571 UniProtKB/Swiss-Prot
  P14104 UniProtKB/Swiss-Prot
  P99022 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Actg1  actin, gamma 1  LOC295810  similar to Actin, cytoplasmic 2 (Gamma-actin)  Data Merged 1643240 APPROVED
2008-08-29 Actg1  actin, gamma 1  Actg1  actin, gamma, cytoplasmic 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC295810  similar to Actin, cytoplasmic 2 (Gamma-actin)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-30 Actg1  actin, gamma, cytoplasmic 1  Actg  actin, gamma, cytoplasmic  Symbol and Name updated 1299863 APPROVED
2005-12-06 Actg  actin, gamma, cytoplasmic  Actg_predicted  actin, gamma, cytoplasmic (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Actg_predicted  actin, gamma, cytoplasmic (predicted)      Symbol and Name status set to approved 70820 APPROVED