Uqcrc1 (ubiquinol-cytochrome c reductase core protein 1) - Rat Genome Database

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Gene: Uqcrc1 (ubiquinol-cytochrome c reductase core protein 1) Rattus norvegicus
Analyze
Symbol: Uqcrc1
Name: ubiquinol-cytochrome c reductase core protein 1
RGD ID: 1303314
Description: Predicted to enable ubiquitin protein ligase binding activity. Involved in response to activity and response to alkaloid. Part of mitochondrial respiratory chain complex III. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human UQCRC1 (ubiquinol-cytochrome c reductase core protein 1); PARTICIPATES IN electron transport chain pathway; Alzheimer's disease pathway; Huntington's disease pathway; INTERACTS WITH 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: complex III subunit 1; core protein I; cytochrome b-c1 complex subunit 1, mitochondrial; MGC93712; ubiquinol-cytochrome c reductase core protein I; ubiquinol-cytochrome-c reductase complex core protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,468,223 - 118,479,968 (+)NCBIGRCr8
mRatBN7.28109,589,735 - 109,601,481 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,589,706 - 109,601,480 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,207,272 - 115,219,022 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,406,459 - 113,418,209 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,249,253 - 111,261,004 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,679,328 - 117,691,073 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,679,278 - 117,691,071 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08117,030,932 - 117,042,820 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,955,930 - 113,967,675 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,975,384 - 113,987,128 (+)NCBI
Celera8108,883,471 - 108,895,222 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one  (ISO)
2,2,2-tetramine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
4,4'-sulfonyldiphenol  (EXP)
8-bromo-3',5'-cyclic GMP  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
ampicillin  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
bilirubin IXalpha  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chromium trinitrate  (ISO)
cisplatin  (EXP,ISO)
clobetasol  (ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
disodium selenite  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furan  (EXP)
gentamycin  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
lamivudine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
LY294002  (ISO)
maneb  (ISO)
metronidazole  (EXP)
molybdenum atom  (ISO)
molybdenum trioxide  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nefazodone  (EXP)
neomycin  (EXP)
oxybenzone  (EXP)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
PCB138  (EXP)
perfluorododecanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
potassium chromate  (ISO)
propiconazole  (ISO)
Pseudolaric acid B  (ISO)
Pyridostigmine bromide  (EXP)
resveratrol  (ISO)
rotenone  (ISO)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium nitrate  (ISO)
streptozocin  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl ethyl ether  (EXP)
thapsigargin  (EXP,ISO)
Triptolide  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vitamin E  (ISO)
zidovudine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Complete coding sequence, intron/exon organization, and chromosomal location of the gene for the core I protein of human ubiquinol-cytochrome c reductase. Hoffman GG, etal., J Biol Chem 1993 Oct 5;268(28):21113-9.
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Decreased levels of complex III core protein 1 and complex V beta chain in brains from patients with Alzheimer's disease and Down syndrome. Kim SH, etal., Cell Mol Life Sci. 2000 Nov;57(12):1810-6.
5. Hippocampal metabolic proteins are modulated in voluntary and treadmill exercise rats. Kirchner L, etal., Exp Neurol. 2008 Jul;212(1):145-51. Epub 2008 Mar 27.
6. Association of gene expression and methylation of UQCRC1 to the predisposition of Alzheimer's disease in a Chinese population. Ma SL, etal., J Psychiatr Res. 2016 May;76:143-7. doi: 10.1016/j.jpsychires.2016.02.010. Epub 2016 Feb 18.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Pressure overload and neurohumoral activation differentially affect the myocardial proteome. Schott P, etal., Proteomics. 2005 Apr;5(5):1372-81.
14. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
15. Mass spectrometric characterization of mitochondrial electron transport complexes: subunits of the rat heart ubiquinol-cytochrome c reductase. Sun G, etal., J Mass Spectrom 2003 May;38(5):531-9.
Additional References at PubMed
PMID:12865426   PMID:14651853   PMID:15489334   PMID:16120479   PMID:16782889   PMID:17634366   PMID:18614015   PMID:19041937   PMID:19725078   PMID:20833797   PMID:26316108   PMID:28676853  
PMID:28750029   PMID:28844695   PMID:32357304   PMID:32819597  


Genomics

Comparative Map Data
Uqcrc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,468,223 - 118,479,968 (+)NCBIGRCr8
mRatBN7.28109,589,735 - 109,601,481 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,589,706 - 109,601,480 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,207,272 - 115,219,022 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,406,459 - 113,418,209 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,249,253 - 111,261,004 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,679,328 - 117,691,073 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,679,278 - 117,691,071 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08117,030,932 - 117,042,820 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,955,930 - 113,967,675 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,975,384 - 113,987,128 (+)NCBI
Celera8108,883,471 - 108,895,222 (+)NCBICelera
Cytogenetic Map8q32NCBI
UQCRC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38348,599,002 - 48,609,646 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl348,599,002 - 48,610,976 (-)EnsemblGRCh38hg38GRCh38
GRCh37348,636,435 - 48,647,079 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,611,436 - 48,622,102 (-)NCBINCBI36Build 36hg18NCBI36
Build 34348,611,435 - 48,622,102NCBI
Celera348,592,174 - 48,602,839 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef348,694,682 - 48,705,348 (-)NCBIHuRef
CHM1_1348,588,742 - 48,599,408 (-)NCBICHM1_1
T2T-CHM13v2.0348,627,962 - 48,639,898 (-)NCBIT2T-CHM13v2.0
Uqcrc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,765,716 - 108,778,709 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9108,765,701 - 108,778,691 (+)EnsemblGRCm39 Ensembl
GRCm389108,936,648 - 108,949,641 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,936,633 - 108,949,623 (+)EnsemblGRCm38mm10GRCm38
MGSCv379108,838,661 - 108,851,686 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369108,793,553 - 108,806,578 (+)NCBIMGSCv36mm8
Celera9108,494,681 - 108,507,601 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.63NCBI
LOC102005965
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955532685,395 - 696,554 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955532685,315 - 691,286 (-)NCBIChiLan1.0ChiLan1.0
LOC100977575
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2248,573,688 - 48,584,412 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1348,578,456 - 48,589,180 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0348,520,870 - 48,531,947 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1349,602,770 - 49,613,717 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl349,602,770 - 49,613,717 (-)Ensemblpanpan1.1panPan2
UQCRC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12040,507,767 - 40,515,854 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2040,506,907 - 40,520,110 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2040,424,996 - 40,433,095 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02040,993,125 - 41,001,225 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2040,992,686 - 41,001,240 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12040,230,564 - 40,238,664 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02040,635,079 - 40,643,433 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02040,916,265 - 40,924,365 (+)NCBIUU_Cfam_GSD_1.0
LOC101956274
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560263,625,445 - 63,635,735 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936529385,851 - 396,230 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936529385,942 - 396,196 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UQCRC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,298,449 - 31,309,516 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,298,449 - 31,308,719 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,542,911 - 34,553,174 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UQCRC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,000,432 - 10,012,524 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2210,000,864 - 10,012,202 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041157,073,473 - 157,085,359 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101719627
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247302,603,089 - 2,613,828 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247302,603,301 - 2,613,105 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Uqcrc1
27 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:116
Count of miRNA genes:98
Interacting mature miRNAs:106
Transcripts:ENSRNOT00000042114
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat

Markers in Region
AA819271  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map81191.4UniSTS
Cytogenetic Map8q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000042114   ⟹   ENSRNOP00000044696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8109,589,706 - 109,601,480 (+)Ensembl
Rnor_6.0 Ensembl8117,679,278 - 117,691,071 (+)Ensembl
RefSeq Acc Id: NM_001004250   ⟹   NP_001004250
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,468,223 - 118,479,968 (+)NCBI
mRatBN7.28109,589,735 - 109,601,481 (+)NCBI
Rnor_6.08117,679,328 - 117,691,073 (+)NCBI
Rnor_5.08117,030,932 - 117,042,820 (+)NCBI
RGSC_v3.48113,955,930 - 113,967,675 (+)RGD
Celera8108,883,471 - 108,895,222 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001004250 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH78923 (Get FASTA)   NCBI Sequence Viewer  
  EDL77131 (Get FASTA)   NCBI Sequence Viewer  
  EDL77132 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000044696
  ENSRNOP00000044696.2
  ENSRNOP00055009416
  ENSRNOP00060023752
  ENSRNOP00065007918
GenBank Protein Q68FY0 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001004250   ⟸   NM_001004250
- Peptide Label: precursor
- UniProtKB: Q68FY0 (UniProtKB/Swiss-Prot),   A6I395 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000044696   ⟸   ENSRNOT00000042114
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q68FY0-F1-model_v2 AlphaFold Q68FY0 1-480 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696318
Promoter ID:EPDNEW_R6842
Type:multiple initiation site
Name:Uqcrc1_1
Description:ubiquinol-cytochrome c reductase core protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08117,679,312 - 117,679,372EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303314 AgrOrtholog
BioCyc Gene G2FUF-29104 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
  PWY-7279 [aerobic respiration II (cytochrome c) (yeast)] BioCyc
BioCyc Pathway Image PWY-3781 BioCyc
  PWY-7279 BioCyc
Ensembl Genes ENSRNOG00000032134 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055007183 UniProtKB/Swiss-Prot
  ENSRNOG00060017294 UniProtKB/Swiss-Prot
  ENSRNOG00065006872 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000042114 ENTREZGENE
  ENSRNOT00000042114.5 UniProtKB/Swiss-Prot
  ENSRNOT00055011906 UniProtKB/Swiss-Prot
  ENSRNOT00060029534 UniProtKB/Swiss-Prot
  ENSRNOT00065010701 UniProtKB/Swiss-Prot
Gene3D-CATH Metalloenzyme, LuxS/M16 peptidase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7106265 IMAGE-MGC_LOAD
InterPro Metalloenz_LuxS/M16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M16_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M16_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:301011 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93712 IMAGE-MGC_LOAD
NCBI Gene 301011 ENTREZGENE
PANTHER CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  METALLOPROTEASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Peptidase_M16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M16_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Uqcrc1 PhenoGen
RatGTEx ENSRNOG00000032134 RatGTEx
  ENSRNOG00055007183 RatGTEx
  ENSRNOG00060017294 RatGTEx
  ENSRNOG00065006872 RatGTEx
Superfamily-SCOP LuxS/MPP-like metallohydrolase UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A6I395 ENTREZGENE, UniProtKB/TrEMBL
  A6I396_RAT UniProtKB/TrEMBL
  Q68FY0 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-09-28 Uqcrc1  ubiquinol-cytochrome c reductase core protein 1  Uqcrc1  ubiquinol-cytochrome c reductase core protein I  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Uqcrc1  ubiquinol-cytochrome c reductase core protein I  Uqcrc1  ubiquinol-cytochrome c reductase core protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Uqcrc1  ubiquinol-cytochrome c reductase core protein 1      Symbol and Name status set to approved 1299863 APPROVED
2005-02-14 Uqcrc1  ubiquinol-cytochrome c reductase core protein I      Symbol and Name status set to provisional 70820 PROVISIONAL