Abca7 (ATP binding cassette subfamily A member 7) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Abca7 (ATP binding cassette subfamily A member 7) Rattus norvegicus
Analyze
Symbol: Abca7
Name: ATP binding cassette subfamily A member 7
RGD ID: 1303134
Description: Predicted to enable ATPase-coupled transmembrane transporter activity; apolipoprotein A-I receptor activity; and floppase activity. Predicted to be involved in several processes, including lipid transport; positive regulation of transport; and regulation of MAPK cascade. Predicted to be located in several cellular components, including apical plasma membrane; phagocytic cup; and ruffle membrane. Predicted to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in Alzheimer's disease 9. Orthologous to human ABCA7 (ATP binding cassette subfamily A member 7); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP-binding cassette sub-family A member 7; ATP-binding cassette, sub-family A (ABC1), member 7; ATP-binding cassette, sub-family A, member 7; ATP-binding cassette, subfamily A (ABC1), member 7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,342,092 - 10,362,094 (-)NCBIGRCr8
mRatBN7.279,691,452 - 9,711,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,691,449 - 9,711,425 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,573,976 - 12,592,469 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,449,312 - 14,467,805 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,310,438 - 12,328,932 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,742,433 - 12,762,423 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,742,433 - 12,762,341 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,912,155 - 12,932,147 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,203,983 - 11,222,960 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1711,203,982 - 11,222,960 (-)NCBI
Celera77,867,206 - 7,885,960 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Cloning of rat ABCA7 and its preferential expression in platelets. Sasaki M, etal., Biochem Biophys Res Commun 2003 May 16;304(4):777-82.
Additional References at PubMed
PMID:12917409   PMID:14570867   PMID:15520449   PMID:16908670   PMID:18429932   PMID:20495215   PMID:23467355   PMID:24097981   PMID:26260791   PMID:27472885   PMID:28091533   PMID:29476059  


Genomics

Comparative Map Data
Abca7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,342,092 - 10,362,094 (-)NCBIGRCr8
mRatBN7.279,691,452 - 9,711,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,691,449 - 9,711,425 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,573,976 - 12,592,469 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,449,312 - 14,467,805 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,310,438 - 12,328,932 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,742,433 - 12,762,423 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,742,433 - 12,762,341 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,912,155 - 12,932,147 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,203,983 - 11,222,960 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1711,203,982 - 11,222,960 (-)NCBI
Celera77,867,206 - 7,885,960 (-)NCBICelera
Cytogenetic Map7q11NCBI
ABCA7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,040,107 - 1,065,572 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,039,997 - 1,065,572 (+)EnsemblGRCh38hg38GRCh38
GRCh37191,040,106 - 1,065,571 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619991,102 - 1,016,571 (+)NCBINCBI36Build 36hg18NCBI36
Celera19970,935 - 998,554 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef19812,691 - 838,952 (+)NCBIHuRef
CHM1_1191,038,376 - 1,065,164 (+)NCBICHM1_1
T2T-CHM13v2.0191,002,776 - 1,030,237 (+)NCBIT2T-CHM13v2.0
Abca7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,832,328 - 79,851,406 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1079,832,328 - 79,851,406 (+)EnsemblGRCm39 Ensembl
GRCm381079,996,453 - 80,015,572 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,996,494 - 80,015,572 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,460,360 - 79,478,317 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,400,744 - 79,418,701 (+)NCBIMGSCv36mm8
Celera1081,012,422 - 81,030,379 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Abca7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,815,562 - 6,836,772 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,818,002 - 6,838,177 (-)NCBIChiLan1.0ChiLan1.0
ABCA7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,374,938 - 5,401,483 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,611,225 - 4,637,922 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01962,811 - 77,897 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1191,016,829 - 1,042,251 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl191,018,095 - 1,042,104 (+)Ensemblpanpan1.1panPan2
ABCA7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,668,371 - 57,684,111 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,667,706 - 57,677,342 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,470,691 - 57,486,228 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,410,598 - 58,426,136 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,410,507 - 58,425,315 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,465,893 - 57,481,504 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,945,423 - 57,961,034 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02058,148,479 - 58,164,018 (-)NCBIUU_Cfam_GSD_1.0
Abca7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,357,348 - 217,374,569 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588461,389 - 477,229 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936588460,308 - 477,382 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCA7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,357,218 - 77,375,180 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,357,161 - 77,375,349 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,621,720 - 77,640,442 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103233590
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.16792,684 - 821,522 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl6792,783 - 821,375 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660818,035,915 - 8,121,412 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abca7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,573,130 - 7,591,038 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248287,572,821 - 7,592,428 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Abca7
48 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:135
Count of miRNA genes:115
Interacting mature miRNAs:123
Transcripts:ENSRNOT00000064886
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat

Markers in Region
RH139906  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.279,691,500 - 9,691,837 (+)MAPPERmRatBN7.2
Rnor_6.0712,742,482 - 12,742,818NCBIRnor6.0
Rnor_5.0712,912,204 - 12,912,540UniSTSRnor5.0
RGSC_v3.4711,203,950 - 11,204,286UniSTSRGSC3.4
Celera77,867,173 - 7,867,509UniSTS
RH 3.4 Map740.7UniSTS
Cytogenetic Map7q11UniSTS
BF390650  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.279,695,031 - 9,695,498 (+)MAPPERmRatBN7.2
Rnor_6.0712,746,013 - 12,746,479NCBIRnor6.0
Rnor_5.0712,915,735 - 12,916,201UniSTSRnor5.0
RGSC_v3.4711,207,481 - 11,207,947UniSTSRGSC3.4
Celera77,870,704 - 7,871,170UniSTS
Cytogenetic Map7q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 12 12 5 12 13 19 1 8
Low 3 43 45 29 14 29 8 11 61 16 40 3 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000064886   ⟹   ENSRNOP00000063805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl79,691,449 - 9,711,425 (-)Ensembl
Rnor_6.0 Ensembl712,742,433 - 12,762,341 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl712,743,992 - 12,746,090 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl712,746,039 - 12,746,952 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl712,742,479 - 12,746,546 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095800   ⟹   ENSRNOP00000095986
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl79,691,449 - 9,711,425 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097711   ⟹   ENSRNOP00000085552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl79,691,452 - 9,711,425 (-)Ensembl
RefSeq Acc Id: NM_207598   ⟹   NP_997481
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,342,092 - 10,361,989 (-)NCBI
mRatBN7.279,691,452 - 9,711,353 (-)NCBI
Rnor_6.0712,742,515 - 12,761,261 (-)NCBI
Rnor_5.0712,912,155 - 12,932,147 (-)NCBI
RGSC_v3.4711,203,983 - 11,222,960 (-)RGD
Celera77,867,206 - 7,885,960 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240871   ⟹   XP_006240933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,342,092 - 10,362,072 (-)NCBI
mRatBN7.279,691,452 - 9,711,441 (-)NCBI
Rnor_6.0712,742,433 - 12,762,423 (-)NCBI
Rnor_5.0712,912,155 - 12,932,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240872   ⟹   XP_006240934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,342,092 - 10,362,070 (-)NCBI
mRatBN7.279,691,452 - 9,711,457 (-)NCBI
Rnor_6.0712,742,433 - 12,762,423 (-)NCBI
Rnor_5.0712,912,155 - 12,932,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240874   ⟹   XP_006240936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,342,092 - 10,362,094 (-)NCBI
mRatBN7.279,691,452 - 9,711,466 (-)NCBI
Rnor_6.0712,742,433 - 12,762,423 (-)NCBI
Rnor_5.0712,912,155 - 12,932,147 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594715   ⟹   XP_017450204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,342,092 - 10,362,072 (-)NCBI
mRatBN7.279,691,452 - 9,711,441 (-)NCBI
Rnor_6.0712,742,433 - 12,762,423 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078645   ⟹   XP_038934573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,342,092 - 10,362,072 (-)NCBI
mRatBN7.279,691,452 - 9,711,441 (-)NCBI
RefSeq Acc Id: XM_039078646   ⟹   XP_038934574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,344,697 - 10,362,077 (-)NCBI
mRatBN7.279,694,082 - 9,711,444 (-)NCBI
RefSeq Acc Id: XM_063263170   ⟹   XP_063119240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,344,318 - 10,362,077 (-)NCBI
RefSeq Acc Id: XR_005486558
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,345,648 - 10,362,078 (-)NCBI
mRatBN7.279,695,008 - 9,711,444 (-)NCBI
RefSeq Acc Id: XR_010052951
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,343,651 - 10,362,077 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_997481   ⟸   NM_207598
- UniProtKB: F1LR67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240936   ⟸   XM_006240874
- Peptide Label: isoform X1
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot),   F1LR67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240934   ⟸   XM_006240872
- Peptide Label: isoform X1
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot),   F1LR67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240933   ⟸   XM_006240871
- Peptide Label: isoform X1
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot),   F1LR67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450204   ⟸   XM_017594715
- Peptide Label: isoform X3
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot),   A0A8I6A4A6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000063805   ⟸   ENSRNOT00000064886
RefSeq Acc Id: XP_038934573   ⟸   XM_039078645
- Peptide Label: isoform X2
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038934574   ⟸   XM_039078646
- Peptide Label: isoform X5
- UniProtKB: Q7TNJ2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSRNOP00000095986   ⟸   ENSRNOT00000095800
RefSeq Acc Id: ENSRNOP00000085552   ⟸   ENSRNOT00000097711
RefSeq Acc Id: XP_063119240   ⟸   XM_063263170
- Peptide Label: isoform X4
Protein Domains
ABC transporter

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TNJ2-F1-model_v2 AlphaFold Q7TNJ2 1-2170 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695047
Promoter ID:EPDNEW_R5572
Type:multiple initiation site
Name:Abca7_1
Description:ATP binding cassette subfamily A member 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0712,762,365 - 12,762,425EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303134 AgrOrtholog
BioCyc Gene G2FUF-34911 BioCyc
Ensembl Genes ENSRNOG00000012939 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055032600 UniProtKB/Swiss-Prot
  ENSRNOG00060024048 UniProtKB/Swiss-Prot
  ENSRNOG00065019847 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000064886 ENTREZGENE
  ENSRNOT00000064886.5 UniProtKB/TrEMBL
  ENSRNOT00000095800.1 UniProtKB/TrEMBL
  ENSRNOT00000097711.1 UniProtKB/TrEMBL
  ENSRNOT00055056345 UniProtKB/Swiss-Prot
  ENSRNOT00060041695 UniProtKB/Swiss-Prot
  ENSRNOT00065033462 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC2_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_transporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABCA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:299609 UniProtKB/Swiss-Prot
NCBI Gene 299609 ENTREZGENE
PANTHER PHOSPHOLIPID-TRANSPORTING ATPASE ABCA7 UniProtKB/Swiss-Prot
  PTHR19229 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR19229:SF49 UniProtKB/TrEMBL
Pfam ABC2_membrane_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_tran UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Abca7 PhenoGen
PROSITE ABC_TRANSPORTER_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012939 RatGTEx
  ENSRNOG00055032600 RatGTEx
  ENSRNOG00060024048 RatGTEx
  ENSRNOG00065019847 RatGTEx
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A4A6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ASJ6_RAT UniProtKB/TrEMBL
  A6K8T5_RAT UniProtKB/TrEMBL
  ABCA7_RAT UniProtKB/Swiss-Prot
  F1LR67 ENTREZGENE, UniProtKB/TrEMBL
  Q7TNJ2 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-19 Abca7  ATP binding cassette subfamily A member 7  Abca7  ATP-binding cassette, subfamily A (ABC1), member 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-11-16 Abca7  ATP-binding cassette, subfamily A (ABC1), member 7  Abca7  ATP-binding cassette, sub-family A (ABC1), member 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Abca7  ATP-binding cassette, sub-family A (ABC1), member 7  ABCA7  ATP-binding cassette, sub-family A, member 7  Name updated 1299863 APPROVED
2005-02-14 ABCA7  ATP-binding cassette, sub-family A, member 7      Symbol and Name status set to provisional 70820 PROVISIONAL