Mir8114 (microRNA 8114) - Rat Genome Database
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Gene: Mir8114 (microRNA 8114) Mus musculus
Analyze
Symbol: Mir8114
Name: microRNA 8114
RGD ID: 9999937
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: Gm27382; mmu-mir-8114
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,775,672 - 153,775,782 (+)NCBIGRCm39mm39
GRCm39 Ensembl1153,775,672 - 153,775,782 (+)Ensembl
GRCm381153,899,926 - 153,900,036 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,899,926 - 153,900,036 (+)EnsemblGRCm38mm10GRCm38
Celera1156,333,046 - 156,333,156 (+)NCBICelera
Cytogenetic Map1G3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:16381832   PMID:23185045  


Genomics


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194200000172200000Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195600000162200000Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1104005680191493284Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112081092168358833Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112081092175641372Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117600000180000000Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121800000153900000Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121800000154000000Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121800000165000000Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122100000165000000Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1123000000157000000Mouse
1301488Tir3b_mtrypansomiasis infection response 3b (mouse)Not determined1128551097157361794Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128800000181500000Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129255120163255255Mouse
1302128Ity3_mimmunity to S. typhimurium 3 (mouse)Not determined11131228571165311895Mouse
14746980Manh50_mmandible shape 50 (mouse)1134255813168255813Mouse
1301458Skts8_mskin tumor susceptibility 8 (mouse)Not determined1135919071169919261Mouse
1301408Lore8_mloss of righting induced by ethanol 8 (mouse)Not determined1136002150170002264Mouse
1357434Obsty1_mobesity 1 (mouse)Not determined1136334204170334348Mouse
1300837Vmbic1_mventral midbrain iron content 1 (mouse)Not determined1139624618173624738Mouse
4141160Cq1_mcholesterol QTL 1 (mouse)Not determined1139624618173624738Mouse
1357602Vtbt2_mvertebral trabecular bone trait 2 (mouse)Not determined1139774467173774646Mouse
1302193Cpfd1_mcerebellum pattern fissures (mouse)Not determined1139774467173774646Mouse
1300740Tne1_mtotal number errors (mouse)Not determined1139774467173774646Mouse
1300696Bpq2_mblood pressure QTL 2 (mouse)Not determined1139774467173774646Mouse
1301523Ccrs1_mcorpus callosum hemisphere surface size 1 (mouse)Not determined1139774467173774646Mouse
1301710Bmd5_mbone mineral density 5 (mouse)Not determined1139774467173774646Mouse
1301894Skull2_mskull morphology 2 (mouse)Not determined1139774467173774646Mouse
11049576Lmr8a_mleishmaniasis resistance 8a (mouse)1139774467173774646Mouse
4142014Wbcq5_mwhite blood cell quantitative locus 5 (mouse)Not determined1141267440175267586Mouse
11533913Rd6m1_mretinal degeneration 6 modifier 1 (mouse)1141405603175405702Mouse
1301467Pcir1_mperiosteal circumference 1 (mouse)Not determined1141405603175405702Mouse
4141233Femwf12_mfemur work to failure 12 (mouse)Not determined141405603175405702Mouse
1301191Stia1_mserum transfer induced arthritis 1 (mouse)Not determined1141405603175405702Mouse
1301151Hdlq14_mHDL QTL 14 (mouse)Not determined1142661973176662164Mouse
1558720Bpq8_mblood pressure QTL 8 (mouse)Not determined1143457095177457233Mouse
11537365Cnes4_mC. neoformans susceptibility locus 4 (mouse)1144621573178621573Mouse
1300571Opfa_mopen field activity (mouse)Not determined1144703778178704023Mouse
12790996Aath2_maortic arch atherosclerosis 2 (mouse)1145250061179250061Mouse
1300934Cfbw1_mcystic fibrosis body weight 1 (mouse)Not determined1145317638179317756Mouse
1301818Ap1q_malcohol preference 1 QTL (mouse)Not determined1147032461167758653Mouse
1301135Pas8_mpulmonary adenoma susceptibility 8 (mouse)Not determined1147249520158405702Mouse
1357567Nidd3k_mNidd3 on KK-A<y> (mouse)Not determined7147249520169211344Mouse
12910522Scgq2_mspontaneous crescentic glomerulonephritis QTL 2 (mouse)1147249520171804689Mouse
1301385Radpf2_mradiation pulmonary fibrosis 2 (mouse)Not determined1147249520183092234Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147249520189251027Mouse
12790984Pcho7_mplasma cholesterol 7 (mouse)1147391821181391821Mouse
12791001Aath6_maortic arch atherosclerosis 6 (mouse)1147391821181391821Mouse
1300777Chol10_mcholesterol 10 (mouse)Not determined9148047933182048047Mouse
10043899Hdlq99_mHDL QTL 99 (mouse)Not determined1148047933182048047Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150317922188627115Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150317922188627115Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150317922188627115Mouse
12903996Cfq5_mconditioned fear QTL 5 (mouse)1150730586159479894Mouse
4141346Skmw12_mskeletal muscle weight 12 (mouse)Not determined150929168184929353Mouse
1300969Sluc5_msusceptibility to lung cancer 5 (mouse)Not determined1151358674185358833Mouse
4142159Nba2_mNew Zealand Black autoimmunity 2 (mouse)Not determined152007542186007711Mouse
1301301Sle1_msystemic lupus erythmatosus susceptibility 1 (mouse)Not determined1152211172186211344Mouse
4142119Bpq21_mblood pressure QTL 21 (mouse)Not determined1152211172186211344Mouse
1301614Cgnz1_mchronic glomerulonephritis in NZM 1 (mouse)Not determined1152211172186211344Mouse
4141554Cfmq1_mcystic fibrosis modifier QTL 1 (mouse)Not determined1152211172186211344Mouse
1357889Lprq3_mlipoprotein QTL 3 (mouse)Not determined1152211172186211344Mouse
1301025Lbw7_mlupus NZB x NZW 7 (mouse)Not determined1152211172186211344Mouse
11251722Ewc1_methanol withdrawal and consumption 1 (mouse)1152305175186305175Mouse
13464138Hdlq107_mHDL QTL 107 (mouse)1152305175186305175Mouse
10054270Nba10_mNew Zealand Black autoimmunity 10 (mouse)Not determined1152919071186706423Mouse
4142149Ctex_mCtla4 expression QTL (mouse)Not determined1153681660175641372Mouse
10412074Nhdlt1_mnon-HDL cholesterol and triglyceride levels 1 (mouse)Not determined1153848421187848536Mouse
10054490Opefa_mopen field activity (mouse)Not determined1153885284187885284Mouse

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:7347
Count of gene targets:4398
Count of transcripts:6521
Interacting mature miRNAs:mmu-miR-8114
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_106194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000183582
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1153,899,926 - 153,900,036 (+)Ensembl
RefSeq Acc Id: NR_106194
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,775,672 - 153,775,782 (+)NCBI
GRCm381153,899,926 - 153,900,036 (+)NCBI
Celera1156,333,046 - 156,333,156 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000099227 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000183582 ENTREZGENE
MGD MGI:5530764 ENTREZGENE
miRBase MI0026046 ENTREZGENE
NCBI Gene Mir8114 ENTREZGENE
PhenoGen Mir8114 PhenoGen
RNAcentral URS000075AA5B RNACentral
  URS000075E34F RNACentral