Mir669f (microRNA 669f) - Rat Genome Database
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Pathways
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Gene: Mir669f (microRNA 669f) Mus musculus
Analyze
Symbol: Mir669f
Name: microRNA 669f
RGD ID: 9686153
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: Mirn6; Mirn669f; mmu-mir-669f
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39210,472,040 - 10,472,160 (+)NCBIGRCm39mm39
GRCm39 Ensembl210,472,040 - 10,472,160 (+)Ensembl
GRCm38210,467,229 - 10,467,349 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl210,467,229 - 10,467,349 (+)EnsemblGRCm38mm10GRCm38
Cytogenetic Map2A1NCBI
cM Map28.22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
RISC complex  (IDA)

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:17989215   PMID:20413612   PMID:20548288   PMID:20668074   PMID:23185045   PMID:24931612  


Genomics


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301838Sluc16_msusceptibility to lung cancer 16 (mouse)Not determined2126524778Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2778910341789249Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388608993591306Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2834628442346384Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2949443443494563Mouse
4142333Tgq10_mtriglyceride QTL 10 (mouse)Not determined125319748Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2841803942418228Mouse
10045633Heal15_mwound healing/regeneration 15 (mouse)Not determined2121984831Mouse
4141836Tgq11_mtriglyceride QTL 11 (mouse)Not determined125319748Mouse
12904743Carcdq3_mcardiac collagen deposition QTL 3 (mouse)2323390328289138Mouse
12903993Opfaq1_mopen field activity QTL 1 (mouse)2967188027132630Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2949443443494563Mouse

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:31114
Count of gene targets:10732
Count of transcripts:17968
Interacting mature miRNAs:mmu-miR-669f-3p, mmu-miR-669f-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_130324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL772216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000103850
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl210,467,229 - 10,467,349 (+)Ensembl
RefSeq Acc Id: NR_130324
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39210,472,040 - 10,472,160 (+)NCBI
GRCm38210,467,229 - 10,467,349 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000077038 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000103850 ENTREZGENE
MGD MGI:3783384 ENTREZGENE
miRBase MI0006287 ENTREZGENE
NCBI Gene Mir669f ENTREZGENE
PhenoGen Mir669f PhenoGen
RNAcentral URS00000BC03C RNACentral
  URS00004C89DD RNACentral
  URS000078D701 RNACentral