Pvrig (poliovirus receptor related immunoglobulin domain containing) - Rat Genome Database

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Gene: Pvrig (poliovirus receptor related immunoglobulin domain containing) Mus musculus
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Symbol: Pvrig
Name: poliovirus receptor related immunoglobulin domain containing
RGD ID: 9676783
MGI Page MGI
Description: Predicted to enable phosphatase binding activity and signaling receptor activity. Predicted to be involved in negative regulation of T cell receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human PVRIG (PVR related immunoglobulin domain containing).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Gm36869; predicted gene, 36869; transmembrane protein PVRIG
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Pvrig-ps  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395138,340,193 - 138,346,953 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5138,340,223 - 138,341,819 (+)EnsemblGRCm39 Ensembl
GRCm385138,341,931 - 138,348,691 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5138,341,961 - 138,343,557 (+)EnsemblGRCm38mm10GRCm38
Celera5135,325,089 - 135,331,893 (+)NCBICelera
Cytogenetic Map5G2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
plasma membrane  (IBA,ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21873635   PMID:26755705   PMID:30659055   PMID:38355793  


Genomics

Comparative Map Data
Pvrig
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395138,340,193 - 138,346,953 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5138,340,223 - 138,341,819 (+)EnsemblGRCm39 Ensembl
GRCm385138,341,931 - 138,348,691 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5138,341,961 - 138,343,557 (+)EnsemblGRCm38mm10GRCm38
Celera5135,325,089 - 135,331,893 (+)NCBICelera
Cytogenetic Map5G2NCBI
PVRIG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,219,248 - 100,221,490 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,218,241 - 100,221,490 (+)EnsemblGRCh38hg38GRCh38
GRCh37799,816,871 - 99,819,113 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,654,807 - 99,657,047 (+)NCBINCBI36Build 36hg18NCBI36
Celera794,552,220 - 94,554,458 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,451,626 - 94,453,866 (+)NCBIHuRef
CHM1_1799,746,940 - 99,749,176 (+)NCBICHM1_1
T2T-CHM13v2.07101,459,061 - 101,461,299 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,176,957 - 99,179,197 (+)NCBI
Pvrig
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81222,474,441 - 22,479,191 (+)NCBIGRCr8
mRatBN7.21217,363,721 - 17,365,577 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1217,364,080 - 17,365,280 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01219,679,671 - 19,681,861 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,680,712 - 19,681,832 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01221,736,342 - 21,737,952 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41217,946,826 - 17,975,559 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1219,286,647 - 19,288,837 (+)NCBICelera
Cytogenetic Map12q11NCBI
Pvrig
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955573592,438 - 595,056 (-)NCBIChiLan1.0ChiLan1.0
PVRIG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,139,172 - 118,140,749 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,403,658 - 166,405,381 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,254,639 - 92,256,592 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17105,687,005 - 105,689,674 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7105,687,005 - 105,689,674 (+)Ensemblpanpan1.1panPan2
PVRIG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.169,314,959 - 9,324,544 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,318,163 - 9,319,499 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha611,018,942 - 11,027,224 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.069,248,638 - 9,256,912 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl69,251,549 - 9,253,111 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.169,101,143 - 9,109,421 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.069,078,192 - 9,083,497 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.069,261,175 - 9,269,459 (-)NCBIUU_Cfam_GSD_1.0
Pvrig
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,569,938 - 133,570,749 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936543465,781 - 467,150 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PVRIG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,230,328 - 8,232,836 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,230,311 - 8,232,840 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.237,576,673 - 7,579,437 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PVRIG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,843,568 - 12,845,648 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,843,811 - 12,845,133 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,435,077 - 3,437,743 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
1301715Elmaz2_melevated maze behavior 2 (mouse)Not determined5125178229141700466Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119945037141700466Mouse
13464143Bbaa2b_mB.burgdorferi-associated arthritis 2b (mouse)5133052969140709801Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121455402151758149Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115156883149157015Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129787831151758149Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129520084151758149Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125133457151758149Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119945037149347326Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124700335151758149Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121555236151758149Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118948964151758149Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115156883149157015Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
11049557Lmr26_mleishmaniasis resistance 26 (mouse)5133925558151758149Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001378438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC157588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000211088   ⟹   ENSMUSP00000147735
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5138,340,223 - 138,341,819 (+)Ensembl
GRCm38.p6 Ensembl5138,341,961 - 138,343,557 (+)Ensembl
RefSeq Acc Id: NM_001378438   ⟹   NP_001365367
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395138,340,193 - 138,346,953 (+)NCBI
GRCm385138,341,931 - 138,348,691 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001365367 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000147735
  ENSMUSP00000147735.2
RefSeq Acc Id: NP_001365367   ⟸   NM_001378438
- Peptide Label: precursor
- UniProtKB: A0A1B0GS01 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000147735   ⟸   ENSMUST00000211088

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A1B0GS01-F1-model_v2 AlphaFold A0A1B0GS01 1-234 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:5596028 AgrOrtholog
Ensembl Genes ENSMUSG00000109713 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000211088 ENTREZGENE
  ENSMUST00000211088.2 UniProtKB/TrEMBL
InterPro TM_PVRIG UniProtKB/TrEMBL
MGD MGI:5596028 ENTREZGENE
NCBI Gene Gm36869 ENTREZGENE
PANTHER PTHR39220 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN PVRIG UniProtKB/TrEMBL
PhenoGen Pvrig PhenoGen
UniProt A0A1B0GS01 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-28 Pvrig  poliovirus receptor related immunoglobulin domain containing  Gm36869  predicted gene, 36869  Symbol and/or name change 5135510 APPROVED