Mir6947 (microRNA 6947) - Rat Genome Database

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Gene: Mir6947 (microRNA 6947) Mus musculus
Analyze
Symbol: Mir6947
Name: microRNA 6947
RGD ID: 9650347
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mmu-mir-6947
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391429,710,845 - 29,710,909 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1429,710,845 - 29,710,909 (+)EnsemblGRCm39 Ensembl
GRCm381429,988,888 - 29,988,952 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1429,988,888 - 29,988,952 (+)EnsemblGRCm38mm10GRCm38
Celera1426,244,720 - 26,244,784 (+)NCBICelera
Cytogenetic Map14A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:22955976  


Genomics

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:29186
Count of gene targets:11290
Count of transcripts:19283
Interacting mature miRNAs:mmu-miR-6947-3p, mmu-miR-6947-5p
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301991Wta3_mweight adult 3 (mouse)Not determined14388747337887650Mouse
4141550Dbm3_mdiabetes modifier 3 (mouse)Not determined514347339143596Mouse
4141265Appd2_mAPP associated premature death 2 (mouse)Not determined14594555230114862Mouse
4141864Mrdq4_mmodifier of retinal degeneration QTL 4 (mouse)Not determined992324548765082Mouse
1300779Dyscalc4_mdystrophic cardiac calcinosis 4 (mouse)Not determined141221287146213007Mouse
27226748Femd8_mfemur midshaft diameter 8, 10 week (mouse)141376927346737457Mouse
27226752Femd4_mfemur midshaft diameter 4, 5 week (mouse)141376927347237457Mouse
1300544Hypn_mhyperinsulinemia (mouse)Not determined141516061649160765Mouse
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141882760452827726Mouse
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
14746973Manh76_mmandible shape 76 (mouse)142228721756287217Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492624858179769Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142792195761137449Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_105912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CT009536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000198991
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1429,710,845 - 29,710,909 (+)Ensembl
GRCm38.p6 Ensembl1429,988,888 - 29,988,952 (+)Ensembl
RefSeq Acc Id: NR_105912
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391429,710,845 - 29,710,909 (+)NCBI
GRCm381429,988,888 - 29,988,952 (+)NCBI
Celera1426,244,720 - 26,244,784 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000104926 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000198991 ENTREZGENE
MGD MGI:5562741 ENTREZGENE
miRBase MI0022794 ENTREZGENE
NCBI Gene Mir6947 ENTREZGENE
PhenoGen Mir6947 PhenoGen
RNAcentral URS000075AAA7 RNACentral
  URS000075AE4E RNACentral
  URS000075CB4D RNACentral