Mir7008 (microRNA 7008) - Rat Genome Database

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Gene: Mir7008 (microRNA 7008) Mus musculus
Analyze
Symbol: Mir7008
Name: microRNA 7008
RGD ID: 9645113
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: Gm27752; mmu-mir-7008
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39331,093,115 - 31,093,177 (+)NCBIGRCm39mm39
GRCm39 Ensembl331,093,115 - 31,093,177 (+)Ensembl
GRCm38331,038,966 - 31,039,028 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl331,038,966 - 31,039,028 (+)EnsemblGRCm38mm10GRCm38
Celera330,950,109 - 30,950,171 (+)NCBICelera
Cytogenetic Map3A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:16381832   PMID:22955976  


Genomics


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33200000142700000Mouse
1300559Thypr3_mthymocyte proliferative response 3 (mouse)Not determined3447125538471355Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3752111468809613Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7521114102782718Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1018416183277639Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31018416183277639Mouse
1357857Lvrq5_mliver weight QTL 5 (mouse)Not determined31018416183277639Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31018416183277639Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1018416183277639Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1018416183277639Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31018416183277639Mouse
1301358Eae20_mexperimental allergic encephalomyelitis 20 (mouse)Not determined31157630445576442Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316000000109800000Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316450000130370000Mouse
4142092Tgq13_mtriglyceride QTL 13 (mouse)Not determined1823401952234019Mouse
1301114Ssial2_msusceptibility to sialadenitis 2 (mouse)Not determined32012071354125954Mouse
12904010Cfq8_mconditioned fear QTL 8 (mouse)32471406831277954Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328900000119100000Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330013439147599053Mouse

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:32152
Count of gene targets:11713
Count of transcripts:20197
Interacting mature miRNAs:mmu-miR-7008-3p, mmu-miR-7008-5p
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_105975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC111093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000184398
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl331,038,966 - 31,039,028 (+)Ensembl
RefSeq Acc Id: NR_105975
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39331,093,115 - 31,093,177 (+)NCBI
GRCm38331,038,966 - 31,039,028 (+)NCBI
Celera330,950,109 - 30,950,171 (+)NCBI
Sequence:
Promoters
RGD ID:6880430
Promoter ID:EPDNEW_M3665
Type:initiation region
Name:Mir7008_1
Description:Mus musculus microRNA 7008 , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38331,038,962 - 31,039,022EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000098890 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000184398 ENTREZGENE
MGD MGI:5531134 ENTREZGENE
miRBase MI0022857 ENTREZGENE
NCBI Gene Mir7008 ENTREZGENE
PhenoGen Mir7008 PhenoGen
RNAcentral URS0000759A16 RNACentral
  URS000075AFEF RNACentral
  URS000075E760 RNACentral