Mir6989 (microRNA 6989) - Rat Genome Database

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Gene: Mir6989 (microRNA 6989) Mus musculus
Analyze
Symbol: Mir6989
Name: microRNA 6989
RGD ID: 9632171
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: Gm27885; mmu-mir-6989
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39196,396,510 - 6,396,574 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl196,396,510 - 6,396,574 (+)EnsemblGRCm39 Ensembl
GRCm38196,346,480 - 6,346,544 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl196,346,480 - 6,346,544 (+)EnsemblGRCm38mm10GRCm38
Celera196,219,461 - 6,219,525 (+)NCBICelera
Cytogenetic Map19ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:22955976  


Genomics

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:29940
Count of gene targets:12167
Count of transcripts:21219
Interacting mature miRNAs:mmu-miR-6989-3p, mmu-miR-6989-5p
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122371338Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132340234Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19332321637323348Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19531332639313470Mouse
25394536Skmw86_mskeletal muscle weight 86, TA (mouse)1950648178957825Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120695286Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19332855120539663Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132875174Mouse
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120328703Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19165376435653927Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19325000035877400Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19332321637323348Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19332321637323348Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19332321637323348Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_105955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC127556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000184812
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl196,396,510 - 6,396,574 (+)Ensembl
GRCm38.p6 Ensembl196,346,480 - 6,346,544 (+)Ensembl
RefSeq Acc Id: NR_105955
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39196,396,510 - 6,396,574 (+)NCBI
GRCm38196,346,480 - 6,346,544 (+)NCBI
Celera196,219,461 - 6,219,525 (+)NCBI
Sequence:
Promoters
RGD ID:13678668
Promoter ID:EPDNEW_M23483
Type:multiple initiation site
Name:Mir6989_1
Description:Mus musculus microRNA 6989 , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38196,346,419 - 6,346,479EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000099230 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000184812 ENTREZGENE
MGD MGI:5531267 ENTREZGENE
miRBase MI0022837 ENTREZGENE
NCBI Gene Mir6989 ENTREZGENE
PhenoGen Mir6989 PhenoGen
RNAcentral URS0000759CFA RNACentral
  URS000075A1FA RNACentral
  URS000075B97D RNACentral