Mir6395 (microRNA 6395) - Rat Genome Database

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Gene: Mir6395 (microRNA 6395) Mus musculus
Analyze
Symbol: Mir6395
Name: microRNA 6395
RGD ID: 9621142
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: Gm27561; mmu-mir-6395
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39834,633,776 - 34,633,866 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl834,633,776 - 34,633,866 (-)EnsemblGRCm39 Ensembl
GRCm38834,166,622 - 34,166,712 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl834,166,622 - 34,166,712 (-)EnsemblGRCm38mm10GRCm38
Celera836,785,399 - 36,785,489 (-)NCBICelera
Cytogenetic Map8A4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:16381832   PMID:22319597  


Genomics

Variants

.
Variants in Mir6395
4 total Variants
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:21857
Count of gene targets:11139
Count of transcripts:19544
Interacting mature miRNAs:mmu-miR-6395
Prediction methods:Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226756Femd2_mfemur midshaft diameter 2, 5 week (mouse)8495000035067154Mouse
1301532Scc8_mcolon tumor susceptibility 8 (mouse)Not determined8721249935110107Mouse
1300906Ap8q_malcohol preference 8 QTL (mouse)Not determined8798418941984342Mouse
10412209Cypr7_mcytokine production 7 (mouse)Not determined8810320142103372Mouse
1301929Eae24_msusceptibility to experimental allergic encephalomyelitis 24 (mouse)Not determined8810320142103372Mouse
1301128Sluc20_msusceptibility to lung cancer 20 (mouse)Not determined8810320142103372Mouse
11532713Sluc42_msusceptibility to lung cancer 42 (mouse)81344721035321225Mouse
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81477316071498244Mouse
1301088Alcw6_malcohol withdrawal 6 (mouse)Not determined81550657249506729Mouse
1300912Daq19_mdirectional asymmetry QTL 19 (mouse)Not determined81550657249506729Mouse
1301298Pgia4_mproteoglycan induced arthritis 4 (mouse)Not determined81656937350569697Mouse
1301550Fembrs2_mfemur breaking strength 2 (mouse)Not determined81832109752321225Mouse
1301160Eae14_msusceptibility to experimental allergic encephalomyelitis 14 (mouse)Not determined81945501853455150Mouse
1300603Cd8ts2_mCD8 T cell subset 2 (mouse)Not determined81945501853455150Mouse
10043974Obq30_mobesity QTL 30 (mouse)Not determined82658332260583322Mouse
13524525Bodwtq7_mbody wweight QTL 7 (mouse)82824955647027681Mouse
1302173Vent1_mventricular size 1 (mouse)Not determined83183168634743564Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83250657271740637Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3250657271740637Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3250657271740637Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3250657271740637Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832506572117965439Mouse
13801029Gripgtt2_mglucose response to intraperitoneal glucose tolerance test 2, females only (mouse)83251002834987154Mouse
10043990Hbnr12_mHeligmosomoides bakeri nematode resistance 12 (mouse)Not determined83327701651290537Mouse
1301936Trigq2_mtriglyceride QTL 2 (mouse)Not determined83429039768290537Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_105820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC167537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000183885
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl834,633,776 - 34,633,866 (-)Ensembl
GRCm38.p6 Ensembl834,166,622 - 34,166,712 (-)Ensembl
RefSeq Acc Id: NR_105820
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39834,633,776 - 34,633,866 (-)NCBI
GRCm38834,166,622 - 34,166,712 (-)NCBI
Celera836,785,399 - 36,785,489 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000098785 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000183885 ENTREZGENE
MGD MGI:5530943 ENTREZGENE
miRBase MI0021930 ENTREZGENE
NCBI Gene Mir6395 ENTREZGENE
PhenoGen Mir6395 PhenoGen
RNAcentral URS000075D971 RNACentral
  URS000075EDD6 RNACentral