Mir5623 (microRNA 5623) - Rat Genome Database
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Gene: Mir5623 (microRNA 5623) Mus musculus
Analyze
Symbol: Mir5623
Name: microRNA 5623
RGD ID: 9617382
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: Gm26068; mir-5623; mmu-mir-5623
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391958,039,599 - 58,039,668 (+)NCBIGRCm39mm39
GRCm381958,051,167 - 58,051,236 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1958,051,167 - 58,051,236 (+)EnsemblGRCm38mm10GRCm38
Celera1960,246,421 - 60,246,490 (+)NCBICelera
Cytogenetic Map19D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:21037258   PMID:21911355  


Genomics


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12790634Ebm1_mEpidermolysis Bullosa modifier 1 (mouse)192500000059000000Mouse
1301451Ath16_matherosclerosis 16 (mouse)Not determined192543847859438566Mouse
13506250Renmq1_mrenal mercury accumulation QTL 1 (mouse)192739715561397266Mouse
4141138Femwf11_mfemur work to failure 11 (mouse)Not determined2815190961431566Mouse
4141562Pas3b_mpulmonary adenoma susceptibility 3b (mouse)Not determined2977296261431566Mouse
1300683Fembm7_mfemoral bone morphometry 7 (mouse)Not determined193015278561431566Mouse
1301410Cd8mts6_mCD8 memory T cell subset 6 (mouse)Not determined193015279261431566Mouse
1301942Pas13_mpulmonary adenoma susceptibility 13 (mouse)Not determined193015279261431566Mouse
1300856Nobq2_mNew Zealand obese QTL 2 (mouse)Not determined193090944161431566Mouse
1301741Lith2_mlithogenic gene 2 (mouse)Not determined193300371961431566Mouse
1301639Stnn_mstriatal neuron number (mouse)Not determined193396351461431566Mouse
4141019Tgq29_mtriglyceride QTL 29 (mouse)Not determined3460834861431566Mouse
1302170Tanidd1_mtally ho associated non-insulin dependednt diabetes mellitus 1 (mouse)Not determined193676416661431566Mouse
4141650Chldq9_mcholesterol and HDL QTL 9 (mouse)Not determined193789455061431566Mouse
1301466T2dm2_mtype 2 diabetes mellitus 2 (mouse)Not determined193838761861431566Mouse
1302104Lfp1_mlong free running period 1 (mouse)Not determined193919563261431566Mouse
10043896Bw21_mbody weight QTL 21 (mouse)Not determined193960763461431566Mouse
1300585Pgia12_mproteoglycan induced arthritis 12 (mouse)Not determined194259842761431566Mouse
11667075Led3_mlate embryonic death 3 (mouse)195109994059135440Mouse
11528548Sluc35_msusceptibility to lung cancer 35 (mouse)195538761859135440Mouse

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:42622
Count of gene targets:15571
Count of transcripts:29565
Interacting mature miRNAs:mmu-miR-5623-3p, mmu-miR-5623-5p
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000176631
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1958,051,167 - 58,051,236 (+)Ensembl
RefSeq Acc Id: NR_049196
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391958,039,599 - 58,039,668 (+)NCBI
GRCm381958,051,167 - 58,051,236 (+)NCBI
Celera1960,246,421 - 60,246,490 (+)NCBI
Sequence:
Promoters
RGD ID:13679866
Promoter ID:EPDNEW_M24082
Type:single initiation site
Name:Mir5623_1
Description:Mus musculus microRNA 5623 , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381958,051,216 - 58,051,276EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000093757 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000176631 ENTREZGENE
MGD MGI:5455845 ENTREZGENE
miRBase MI0019191 ENTREZGENE
NCBI Gene Mir5623 ENTREZGENE
PhenoGen Mir5623 PhenoGen
RNAcentral URS00005EA889 RNACentral
  URS000075B83B RNACentral
  URS000075ECE6 RNACentral