Mir6368 (microRNA 6368) - Rat Genome Database

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Gene: Mir6368 (microRNA 6368) Mus musculus
Analyze
Symbol: Mir6368
Name: microRNA 6368
RGD ID: 9608071
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: Gm27800; mmu-mir-6368
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391328,894,764 - 28,894,856 (-)NCBIGRCm39mm39
GRCm39 Ensembl1328,894,764 - 28,894,856 (-)Ensembl
GRCm381328,710,781 - 28,710,873 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1328,710,781 - 28,710,873 (-)EnsemblGRCm38mm10GRCm38
Celera1328,934,540 - 28,934,632 (-)NCBICelera
Cytogenetic Map13A3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
carbon nanotube  (EXP)
icariin  (EXP)

References
Additional References at PubMed
PMID:16381832   PMID:22319597  


Genomics


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301255Cd4ts6_mCD4 T cell subset 6 (mouse)Not determined13133994099Mouse
10449140Eosn2_meosinophil differential 2 (mouse)134672634046726Mouse
15039338Nmrs34_mNAFLD-associated magnetic resonance shift 34 (mouse)134672634046726Mouse
1301455Bmd3_mbone mineral density 3 (mouse)Not determined13329344237293650Mouse
10045624Heal24_mwound healing/regeneration (mouse)Not determined13329344237293650Mouse
10045625Heal23_mwound healing/regeneration 23 (mouse)Not determined13329344237293650Mouse
1301367Twq1_mtestis weight QTL 1 (mouse)Not determined13343134237431502Mouse
1301733Heal3_mwound healing/regeneration 3 (mouse)Not determined13349603037496173Mouse
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13390000075900000Mouse
1558898Hpi1_mhapatic PMN infiltration 1 (mouse)Not determined13436402652947604Mouse
10402494Igmsc1_mimmunoglobulin M secreting cells 1 (mouse)Not determined131699396044765084Mouse
1301984Pbd2_mpeak bone density 2 (mouse)Not determined131701492338763430Mouse
1301880Hypt_mhypertension (mouse)Not determined131797280951972941Mouse
13463469Gssq1_mglomerulosclerosis severity QTL 1 (mouse)131887692552877067Mouse
12880423V25Dq7_mvitamin D inactive form serum level QTL 7 (mouse)131940000053400000Mouse
1301015Sysbp2_msystolic blood pressure 2 (mouse)Not determined132029344259673791Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20293442112761890Mouse
1357591Tesq1_mtestis weight QTL 1 (mouse)Not determined132043134255572704Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132043134272237070Mouse
10045618Heal17_mwound healing/regeneration 17 (mouse)Not determined132056296354563080Mouse
1558844Lith15_mlithogenic gene 15 (mouse)Not determined132176326255763430Mouse
4142489Ath25_matherosclerosis 25 (mouse)Not determined2568305359683053Mouse
10401111Pgia40_mproteoglycan induced arthritis 40 (mouse)Not determined132776499361765084Mouse
1300710Pcd4ts2_mp-glycoprotein positive CD4 T cell subset 2 (mouse)Not determined132805696662057068Mouse
1357802Vtbt15_mvertebral trabecular bone trait 15 (mouse)Not determined132806390362064039Mouse
10045621Heal21_mwound healing/regeneration 21 (mouse)Not determined132806390362064039Mouse

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:19059
Count of gene targets:8188
Count of transcripts:13494
Interacting mature miRNAs:mmu-miR-6368
Prediction methods:Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_105787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL606488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000184136
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1328,710,781 - 28,710,873 (-)Ensembl
RefSeq Acc Id: NR_105787
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391328,894,764 - 28,894,856 (-)NCBI
GRCm381328,710,781 - 28,710,873 (-)NCBI
Celera1328,934,540 - 28,934,632 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000099158 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000184136 ENTREZGENE
MGD MGI:5531182 ENTREZGENE
miRBase MI0021897 ENTREZGENE
NCBI Gene Mir6368 ENTREZGENE
PhenoGen Mir6368 PhenoGen
RNAcentral URS000075A27A RNACentral
  URS000075E5EB RNACentral