Mir6345 (microRNA 6345) - Rat Genome Database

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Gene: Mir6345 (microRNA 6345) Mus musculus
Analyze
Symbol: Mir6345
Name: microRNA 6345
RGD ID: 9599101
MGI Page MGI
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: Gm27819; mmu-mir-6345
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,279,880 - 93,280,007 (+)NCBIGRCm39mm39
GRCm39 Ensembl193,279,880 - 93,280,007 (+)Ensembl
GRCm38193,352,158 - 93,352,285 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,352,158 - 93,352,285 (+)EnsemblGRCm38mm10GRCm38
Celera196,296,756 - 96,296,883 (+)NCBICelera
Cytogenetic Map1DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:22319597  


Genomics


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134721057150318120Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134721057150318120Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134721057150318120Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139093727126517573Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162907596120601949Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163880843153681816Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167300000129800000Mouse
1302146Cocrb1_mcocaine related behavior 1 (mouse)Not determined170205811104211835Mouse
1300976Bmd19_mbone mineral density 19 (mouse)Not determined173227055108910684Mouse
4142394Mssq1_mmandible size and shape QTL 1 (mouse)Not determined73687970107688108Mouse
1301304Hrq3_mheart rate quantitative locus 3 (mouse)Not determined173687970107688108Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173716016147249632Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74477076148839837Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174952818133363199Mouse
27095931Pglq1_mpelvic girdle length QTL 1, 5 week (mouse)176000000128600000Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)176000000148900000Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
1558928Mord2_mmodifier of retinal degeneration 2 (mouse)Not determined177146478110608345Mouse
14697706Stsl3a_mSalmonella typhimurium susceptibility locus 3a (mouse)17750000095900000Mouse
4141725Wbcq4_mwhite blood cell quantitative locus 4 (mouse)Not determined179930958113931066Mouse
12050069Nabq1_mnasal bone morphology QTL 1 (mouse)179930958113931066Mouse
13452395Leusq2_mleucocytosis susceptibility QTL 2 (mouse)180267876126458780Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782314261147249632Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182665468135687641Mouse
10412238Alpq5_malcohol preference QTL 5 (mouse)Not determined182904910116904910Mouse
12791004Aath7_maortic arch atherosclerosis 7 (mouse)182904910116904910Mouse
11667074Led2_mlate embryonic death 2 (mouse)185768306117267351Mouse
12790991Aath1_maortic arch atherosclerosis 1 (mouse)186556204120556204Mouse
4141329Mleu1_mmyeloid leukemia survival 1 (mouse)Not determined89858782123858782Mouse
15039333Nmrs1_mNAFLD-associated magnetic resonance shift 1 (mouse)189858782123858782Mouse
4141347Reb1_mrepetitive behavior 1 (mouse)Not determined91540544100485942Mouse
1357760Synch3_msynechia 3 (mouse)Not determined192973712126973820Mouse
4141627Bwq7_mbody weight, QTL 7 (mouse)Not determined193013187124570059Mouse

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:11502
Count of gene targets:5854
Count of transcripts:9215
Interacting mature miRNAs:mmu-miR-6345
Prediction methods:Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_105763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000184286
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl193,352,158 - 93,352,285 (+)Ensembl
RefSeq Acc Id: NR_105763
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,279,880 - 93,280,007 (+)NCBI
GRCm38193,352,158 - 93,352,285 (+)NCBI
Celera196,296,756 - 96,296,883 (+)NCBI
Sequence:
Promoters
RGD ID:6874546
Promoter ID:EPDNEW_M724
Type:single initiation site
Name:Mir6345_1
Description:Mus musculus microRNA 6345 , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38193,352,205 - 93,352,265EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000098689 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000184286 ENTREZGENE
MGD MGI:5531201 ENTREZGENE
miRBase MI0021873 ENTREZGENE
NCBI Gene Mir6345 ENTREZGENE
PhenoGen Mir6345 PhenoGen
RNAcentral URS000075BF33 RNACentral
  URS000075D2B9 RNACentral