Strit1 (small transmembrane regulator of ion transport 1) - Rat Genome Database
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Gene: Strit1 (small transmembrane regulator of ion transport 1) Mus musculus
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Symbol: Strit1
Name: small transmembrane regulator of ion transport 1
RGD ID: 9592078
MGI Page MGI
Description: Exhibits enzyme activator activity. Involved in positive regulation of calcium ion transport and regulation of striated muscle contraction. Localizes to sarcoplasmic reticulum membrane. Orthologous to human STRIT1 (small transmembrane regulator of ion transport 1); INTERACTS WITH benzo[a]pyrene (ortholog); sunitinib (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DWORF; Gm34302; predicted gene, 34302; Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF; SERCA regulator DWORF
RGD Orthologs
Human
Bonobo
Dog
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39363,388,516 - 63,391,327 (-)NCBIGRCm39mm39
GRCm39 Ensembl363,388,533 - 63,391,300 (-)Ensembl
GRCm38363,481,095 - 63,483,906 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl363,481,112 - 63,483,879 (-)EnsemblGRCm38mm10GRCm38
Celera363,154,551 - 63,157,363 (-)NCBICelera
Cytogenetic Map3E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References
Additional References at PubMed
PMID:26816378   PMID:30299255  


Genomics

Comparative Map Data
Strit1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39363,388,516 - 63,391,327 (-)NCBIGRCm39mm39
GRCm39 Ensembl363,388,533 - 63,391,300 (-)Ensembl
GRCm38363,481,095 - 63,483,906 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl363,481,112 - 63,483,879 (-)EnsemblGRCm38mm10GRCm38
Celera363,154,551 - 63,157,363 (-)NCBICelera
Cytogenetic Map3E1NCBI
STRIT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3155,290,227 - 155,293,683 (-)EnsemblGRCh38hg38GRCh38
GRCh383155,290,227 - 155,293,683 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373155,008,016 - 155,011,472 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map3q25.2NCBI
HuRef3152,402,230 - 152,405,698 (-)NCBIHuRef
CHM1_13154,971,058 - 154,974,543 (-)NCBICHM1_1
STRIT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13160,398,665 - 160,402,152 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3160,399,367 - 160,402,051 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03152,346,768 - 152,351,244 (-)NCBIMhudiblu_PPA_v0panPan3
STRIT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12349,131,218 - 49,134,728 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2349,131,221 - 49,134,942 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2349,006,134 - 49,027,054 (-)NCBI
ROS_Cfam_1.02349,764,376 - 49,785,339 (-)NCBI
UMICH_Zoey_3.12349,350,344 - 49,371,236 (-)NCBI
UNSW_CanFamBas_1.02349,400,356 - 49,421,263 (-)NCBI
UU_Cfam_GSD_1.02349,683,533 - 49,704,426 (-)NCBI
Strit1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_ltri_2NW_02440560287,066,687 - 87,069,867 (+)NCBI
STRIT1
(Chlorocebus sabaeus - African green monkey)
No map positions available.


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33200000142700000Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3752111468809613Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7521114102782718Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1018416183277639Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31018416183277639Mouse
1357857Lvrq5_mliver weight QTL 5 (mouse)Not determined31018416183277639Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31018416183277639Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1018416183277639Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1018416183277639Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31018416183277639Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316000000109800000Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316450000130370000Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328900000119100000Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330013439147599053Mouse
1300961Bh4p_mbar holding four paws (mouse)Not determined33188340565883548Mouse
10412073Ssen2_msuseptibility to Sendai virus 2 (mouse)Not determined33358101667581166Mouse
9587784Afw13_mabdominal fat weight QTL 13 (mouse)Not determined33384462467844807Mouse
10043882Bwtq13_mbody weight QTL 13 (mouse)Not determined33384462467844807Mouse
15039332Nmrs6_mNAFLD-associated magnetic resonance shift 6 (mouse)33426332068263320Mouse
15039336Nmrs2_mNAFLD-associated magnetic resonance shift 2 (mouse)33466868268668682Mouse
18337272Bmd46_mbone mineral density 46, males (mouse)33550000069500000Mouse
14746977Manh53_mmandible shape 53 (mouse)33601785970017859Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337120713143647422Mouse
1300587Aod2_mautoimmune ovarian dysgenesis 2 (mouse)Not determined33712559368809613Mouse
1301585Cd4ts1_mCD4 T cell subset 1 (mouse)Not determined33979668173796810Mouse
10755516Amzn1_manatomical modifier of Zfp423 1 (mouse)33979668173796810Mouse
11039513Ltpr3a_mLeishmania tropica response 3a (mouse)33979668173796810Mouse
11041901Lmr11b_mleishmaniasis resistance 11b (mouse)33979668173796810Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)341000000116000000Mouse
26884389Skwq10_mskull length QTL 10, 16 week (mouse)34400000065400000Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)344000000101700000Mouse
4141079Ath23_matherosclerosis 23 (mouse)Not determined4945016083450160Mouse
1301824Susp_msuppressor of superoxide production (mouse)Not determined34958758483587697Mouse
1300895Hdl5_mHDL level 5 (mouse)Not determined34958758483587697Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)352000000102400000Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352300000137500000Mouse
1301917Tshp4_mtooth shape 4 (mouse)Not determined35271817686718412Mouse
1357585Manln3_mmandible length 3 (mouse)Not determined35271817686718412Mouse
1300593Skull4_mskull morphology 4 (mouse)Not determined35271817686718412Mouse
13464139Nhdlq17_mnon-HDL QTL 17 (mouse)35301585087015850Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356796681100556821Mouse
12880419V125Dq4_mvitamin D active form serum level QTL 4 (mouse)35900000093000000Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36183275495832934Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000192926   ⟹   ENSMUSP00000147363
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl363,481,112 - 63,483,879 (-)Ensembl
RefSeq Acc Id: NM_001369305   ⟹   NP_001356234
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39363,388,516 - 63,391,327 (-)NCBI
GRCm38363,481,095 - 63,483,906 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001369306   ⟹   NP_001356235
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39363,388,516 - 63,391,327 (-)NCBI
GRCm38363,481,095 - 63,483,906 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001356234 (Get FASTA)   NCBI Sequence Viewer  
  NP_001356235 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein P0DN83 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001356235   ⟸   NM_001369306
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001356234   ⟸   NM_001369305
- Peptide Label: isoform 1
RefSeq Acc Id: ENSMUSP00000147363   ⟸   ENSMUST00000192926


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:5593461 AgrOrtholog
Ensembl Genes ENSMUSG00000103476 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000147363 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000192926 ENTREZGENE, UniProtKB/Swiss-Prot
MGD MGI:5593461 ENTREZGENE
NCBI Gene Gm34302 ENTREZGENE
PhenoGen Strit1 PhenoGen
UniProt DWORF_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-09 Strit1  small transmembrane regulator of ion transport 1  Gm34302  predicted gene, 34302  Symbol and/or name change 5135510 APPROVED