Polm (DNA polymerase mu) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Polm (DNA polymerase mu) Chinchilla lanigera
Analyze
Symbol: Polm
Name: DNA polymerase mu
RGD ID: 9067189
Description: INVOLVED IN B cell differentiation (ortholog); somatic hypermutation of immunoglobulin genes (ortholog); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA-directed DNA/RNA polymerase mu; polymerase (DNA directed), mu
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,886,291 - 7,895,085 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554567,886,182 - 7,893,800 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Polm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,886,291 - 7,895,085 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554567,886,182 - 7,893,800 (+)NCBIChiLan1.0ChiLan1.0
POLM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,072,062 - 44,082,530 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,072,062 - 44,082,530 (-)EnsemblGRCh38hg38GRCh38
GRCh37744,111,661 - 44,122,129 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,078,371 - 44,088,607 (-)NCBINCBI36Build 36hg18NCBI36
Build 34743,885,085 - 43,895,322NCBI
Celera744,209,796 - 44,220,079 (-)NCBICelera
Cytogenetic Map7p13NCBI
HuRef743,997,135 - 44,007,419 (-)NCBIHuRef
CHM1_1744,115,725 - 44,126,007 (-)NCBICHM1_1
T2T-CHM13v2.0744,230,561 - 44,241,032 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,151,339 - 44,161,618 (-)NCBI
Polm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,777,860 - 5,788,831 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,777,860 - 5,788,016 (-)EnsemblGRCm39 Ensembl
GRCm38115,827,860 - 5,838,832 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,827,860 - 5,838,016 (-)EnsemblGRCm38mm10GRCm38
MGSCv37115,727,863 - 5,738,019 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,727,863 - 5,737,763 (-)NCBIMGSCv36mm8
Celera116,319,454 - 6,329,603 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.87NCBI
Polm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,921,039 - 84,930,649 (-)NCBIGRCr8
mRatBN7.21480,707,075 - 80,716,677 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,706,345 - 80,717,086 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,109,494 - 85,119,056 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,349,591 - 86,359,153 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,798,913 - 82,808,475 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,069,378 - 86,079,327 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,069,016 - 86,078,954 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,761,187 - 86,771,152 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,491,716 - 86,501,294 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11486,510,861 - 86,520,439 (-)NCBI
Celera1479,591,849 - 79,601,427 (-)NCBICelera
Cytogenetic Map14q21NCBI
POLM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2648,983,399 - 48,993,783 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1797,306,089 - 97,318,530 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,785,797 - 44,796,624 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1744,852,594 - 44,862,816 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl744,852,594 - 44,862,816 (-)Ensemblpanpan1.1panPan2
POLM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha162,018,930 - 2,026,262 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01614,835,737 - 14,843,073 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,835,697 - 14,845,960 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01614,466,925 - 14,474,259 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,447,398 - 14,454,737 (+)NCBIUU_Cfam_GSD_1.0
Polm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511899,821,348 - 99,830,709 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,032,920 - 19,042,432 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,032,995 - 19,042,400 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1851,079,503 - 51,088,781 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11851,077,845 - 51,091,354 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21855,971,589 - 55,982,831 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POLM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,585,912 - 14,596,127 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2114,586,164 - 14,599,248 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660627,918,848 - 7,928,889 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Polm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,932,064 - 7,938,365 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247407,932,179 - 7,939,133 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000010799   ⟹   ENSCLAP00000010667
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554567,886,291 - 7,895,085 (+)Ensembl
RefSeq Acc Id: XM_005396675   ⟹   XP_005396732
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554567,886,183 - 7,893,800 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005396676   ⟹   XP_005396733
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554567,886,182 - 7,893,800 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005396677   ⟹   XP_005396734
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554567,886,183 - 7,893,800 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005396678   ⟹   XP_005396735
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554567,886,182 - 7,893,800 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005396679   ⟹   XP_005396736
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554567,886,182 - 7,893,800 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005396732   ⟸   XM_005396675
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V5Z3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005396733   ⟸   XM_005396676
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005396735   ⟸   XM_005396678
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005396736   ⟸   XM_005396679
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_005396734   ⟸   XM_005396677
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCLAP00000010667   ⟸   ENSCLAT00000010799
Protein Domains
BRCT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007360 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000010799 ENTREZGENE
  ENSCLAT00000010799.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.110 UniProtKB/TrEMBL
  3.30.210.10 UniProtKB/TrEMBL
  3.30.460.10 UniProtKB/TrEMBL
  3.40.50.10190 UniProtKB/TrEMBL
  5' to 3' exonuclease, C-terminal subdomain UniProtKB/TrEMBL
InterPro BRCT_dom UniProtKB/TrEMBL
  BRCT_dom_sf UniProtKB/TrEMBL
  DNA-dir_DNA_pol_X UniProtKB/TrEMBL
  DNA/RNApol_mu UniProtKB/TrEMBL
  DNA_pol-X_BS UniProtKB/TrEMBL
  DNA_pol_b-like_N UniProtKB/TrEMBL
  DNA_pol_B_palm_palm UniProtKB/TrEMBL
  DNA_pol_lambd_fingers_domain UniProtKB/TrEMBL
  DNA_pol_lamdba_lyase_dom_sf UniProtKB/TrEMBL
  DNA_Pol_thumb_sf UniProtKB/TrEMBL
  DNA_pol_X UniProtKB/TrEMBL
  NT_sf UniProtKB/TrEMBL
  PolB_thumb UniProtKB/TrEMBL
  TdT/Mu UniProtKB/TrEMBL
NCBI Gene Polm ENTREZGENE
PANTHER DNA-DIRECTED DNA/RNA POLYMERASE MU UniProtKB/TrEMBL
  PTHR11276 UniProtKB/TrEMBL
Pfam DNA_pol_B_palm UniProtKB/TrEMBL
  DNA_pol_B_thumb UniProtKB/TrEMBL
  DNA_pol_lambd_f UniProtKB/TrEMBL
  HHH_8 UniProtKB/TrEMBL
PIRSF DNA_NT UniProtKB/TrEMBL
  DNApol_mu UniProtKB/TrEMBL
PRINTS DNAPOLX UniProtKB/TrEMBL
  DNAPOLXTDT UniProtKB/TrEMBL
PROSITE BRCT UniProtKB/TrEMBL
  DNA_POLYMERASE_X UniProtKB/TrEMBL
SMART POLXc UniProtKB/TrEMBL
Superfamily-SCOP PsbU/PolX domain-like UniProtKB/TrEMBL
  SSF47802 UniProtKB/TrEMBL
  SSF52113 UniProtKB/TrEMBL
  SSF81301 UniProtKB/TrEMBL
UniProt A0A8C2V5Z3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-26 Polm  DNA polymerase mu    polymerase (DNA directed), mu  Symbol and/or name change 5135510 APPROVED