Bhlhe41 (basic helix-loop-helix family member e41) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Bhlhe41 (basic helix-loop-helix family member e41) Chinchilla lanigera
Analyze
Symbol: Bhlhe41
Name: basic helix-loop-helix family member e41
RGD ID: 9066457
Description: ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN circadian regulation of gene expression (ortholog); circadian rhythm (ortholog); negative regulation of DNA-templated transcription (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH esophageal cancer (ortholog); Familial Natural Short Sleep 1 (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: basic helix-loop-helix family, member e41; class E basic helix-loop-helix protein 41
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541321,100,021 - 21,103,358 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Bhlhe41
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541321,100,021 - 21,103,358 (-)NCBIChiLan1.0ChiLan1.0
BHLHE41
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381226,120,030 - 26,125,037 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1226,120,030 - 26,125,037 (-)EnsemblGRCh38hg38GRCh38
GRCh371226,272,963 - 26,277,970 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,164,226 - 26,169,113 (-)NCBINCBI36Build 36hg18NCBI36
Build 341226,164,227 - 26,169,113NCBI
Celera1231,419,506 - 31,424,550 (-)NCBICelera
Cytogenetic Map12p12.1NCBI
HuRef1226,043,295 - 26,047,960 (-)NCBIHuRef
CHM1_11226,237,976 - 26,243,020 (-)NCBICHM1_1
T2T-CHM13v2.01225,992,585 - 25,998,690 (-)NCBIT2T-CHM13v2.0
Bhlhe41
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396145,803,969 - 145,811,146 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6145,803,969 - 145,811,284 (-)EnsemblGRCm39 Ensembl
GRCm386145,858,243 - 145,865,420 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6145,858,243 - 145,865,558 (-)EnsemblGRCm38mm10GRCm38
MGSCv376145,811,257 - 145,813,860 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366145,819,896 - 145,822,499 (-)NCBIMGSCv36mm8
Celera6148,934,952 - 148,937,555 (-)NCBICelera
Cytogenetic Map6G3NCBI
cM Map677.7NCBI
Bhlhe41
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84180,565,003 - 180,569,415 (-)NCBIGRCr8
mRatBN7.24178,834,264 - 178,838,618 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4178,834,271 - 178,838,468 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4185,117,084 - 185,121,450 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04180,901,598 - 180,905,964 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04179,522,031 - 179,526,399 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04180,230,742 - 180,235,138 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4180,232,382 - 180,234,804 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04244,394,139 - 244,398,535 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera4167,334,944 - 167,338,512 (-)NCBICelera
Cytogenetic Map4q44NCBI
BHLHE41
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21070,697,481 - 70,702,552 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11270,693,542 - 70,698,949 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01260,194,758 - 60,199,344 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11262,806,113 - 62,810,773 (+)NCBIpanpan1.1PanPan1.1panPan2
BHLHE41
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12721,464,302 - 21,469,119 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2724,913,768 - 24,918,529 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02721,659,233 - 21,663,998 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2721,659,186 - 21,663,998 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12721,469,068 - 21,473,810 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02721,491,838 - 21,496,575 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02725,081,155 - 25,085,938 (-)NCBIUU_Cfam_GSD_1.0
Bhlhe41
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494583,384,039 - 83,391,789 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365481,306,939 - 1,314,678 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BHLHE41
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl547,686,404 - 47,692,762 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1547,687,662 - 47,692,761 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2551,429,074 - 51,433,848 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BHLHE41
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11125,872,139 - 25,879,985 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1125,874,108 - 25,876,826 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660699,196,174 - 9,200,076 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bhlhe41
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475213,000,525 - 13,003,079 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475213,000,238 - 13,004,777 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_013511397   ⟹   XP_013366851
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541321,100,021 - 21,103,358 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013366851 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000022758.1
Reference Protein Sequences
RefSeq Acc Id: XP_013366851   ⟸   XM_013511397
- Sequence:
Protein Domains
bHLH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015603 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000022967.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene Bhlhe41 ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED UniProtKB/TrEMBL
  CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 41 UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
UniProt A0A8C2YTT1_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Bhlhe41  basic helix-loop-helix family member e41    basic helix-loop-helix family, member e41  Symbol and/or name change 5135510 APPROVED