Nfu1 (NFU1 iron-sulfur cluster scaffold) - Rat Genome Database

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Gene: Nfu1 (NFU1 iron-sulfur cluster scaffold) Chinchilla lanigera
Analyze
Symbol: Nfu1
Name: NFU1 iron-sulfur cluster scaffold
RGD ID: 9064652
Description: ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (ortholog); iron ion binding (ortholog); INVOLVED IN iron-sulfur cluster assembly (ortholog); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; ASSOCIATED WITH genetic disease (ortholog); multiple mitochondrial dysfunctions syndrome (ortholog); multiple mitochondrial dysfunctions syndrome 1 (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NFU1 iron-sulfur cluster scaffold homolog; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542415,647,623 - 15,674,573 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542415,648,213 - 15,671,383 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)
mitochondrion  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nfu1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542415,647,623 - 15,674,573 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542415,648,213 - 15,671,383 (+)NCBIChiLan1.0ChiLan1.0
NFU1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38269,395,750 - 69,439,567 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl269,396,113 - 69,437,628 (-)EnsemblGRCh38hg38GRCh38
GRCh37269,622,882 - 69,666,699 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36269,476,756 - 69,518,257 (-)NCBINCBI36Build 36hg18NCBI36
Build 34269,534,905 - 69,576,404NCBI
Celera269,473,252 - 69,514,522 (-)NCBICelera
Cytogenetic Map2p13.3NCBI
HuRef269,359,753 - 69,401,132 (-)NCBIHuRef
CHM1_1269,552,650 - 69,594,074 (-)NCBICHM1_1
T2T-CHM13v2.0269,408,096 - 69,451,867 (-)NCBIT2T-CHM13v2.0
Nfu1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39686,986,040 - 87,005,443 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl686,986,218 - 87,005,443 (+)EnsemblGRCm39 Ensembl
GRCm38687,009,234 - 87,028,461 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,009,236 - 87,028,461 (+)EnsemblGRCm38mm10GRCm38
MGSCv37686,959,830 - 86,978,455 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36686,975,538 - 86,994,049 (+)NCBIMGSCv36mm8
Celera688,949,192 - 88,967,878 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map637.76NCBI
Nfu1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84121,016,316 - 121,036,925 (+)NCBIGRCr8
mRatBN7.24119,458,981 - 119,480,162 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4119,459,061 - 119,480,373 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4124,932,395 - 124,952,928 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04120,707,135 - 120,727,667 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04119,331,386 - 119,351,919 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04118,814,284 - 118,834,955 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4118,814,284 - 118,834,955 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04183,383,769 - 183,404,239 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44121,184,017 - 121,187,110 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14121,401,604 - 121,432,159 (+)NCBI
Celera4108,428,818 - 108,449,350 (+)NCBICelera
Cytogenetic Map4q34NCBI
NFU1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21256,976,064 - 57,017,749 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A56,980,179 - 57,021,685 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A69,438,979 - 69,480,470 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A70,559,872 - 70,600,301 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A70,559,872 - 70,600,301 (-)Ensemblpanpan1.1panPan2
NFU1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11068,134,865 - 68,161,841 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1068,134,902 - 68,335,988 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1068,026,707 - 68,053,938 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01069,158,089 - 69,185,558 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1069,157,090 - 69,186,295 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11068,838,469 - 68,865,703 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01069,139,057 - 69,166,520 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01069,436,279 - 69,463,557 (-)NCBIUU_Cfam_GSD_1.0
Nfu1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629214,858,369 - 14,890,628 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649113,679,629 - 13,712,988 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649113,680,669 - 13,712,924 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFU1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl372,983,136 - 73,024,663 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1372,983,075 - 73,013,227 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2376,438,277 - 76,442,256 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NFU1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11437,690,329 - 37,731,093 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1437,690,656 - 37,730,819 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604574,263,441 - 74,305,552 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nfu1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247623,887,124 - 3,917,406 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000012266   ⟹   ENSCLAP00000012125
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542415,647,623 - 15,674,573 (+)Ensembl
RefSeq Acc Id: XM_005385648   ⟹   XP_005385705
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542415,648,213 - 15,671,383 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514673   ⟹   XP_013370127
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542415,651,682 - 15,671,383 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005385705 (Get FASTA)   NCBI Sequence Viewer  
  XP_013370127 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000012125
  ENSCLAP00000012125.1
Reference Protein Sequences
RefSeq Acc Id: XP_005385705   ⟸   XM_005385648
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VCV5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013370127   ⟸   XM_013514673
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000012125   ⟸   ENSCLAT00000012266
Protein Domains
Scaffold protein Nfu/NifU N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000008359 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000012266 ENTREZGENE
  ENSCLAT00000012266.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.70 UniProtKB/TrEMBL
  3.30.300.130 UniProtKB/TrEMBL
InterPro FSCA_dom_sf UniProtKB/TrEMBL
  Nfu/NifU_N UniProtKB/TrEMBL
  Nfu/NifU_N_sf UniProtKB/TrEMBL
  NIF_FeS_clus_asmbl_NifU_C UniProtKB/TrEMBL
NCBI Gene Nfu1 ENTREZGENE
PANTHER IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED UniProtKB/TrEMBL
  NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam Nfu_N UniProtKB/TrEMBL
  NifU UniProtKB/TrEMBL
SMART Nfu_N UniProtKB/TrEMBL
Superfamily-SCOP SSF110836 UniProtKB/TrEMBL
  SSF117916 UniProtKB/TrEMBL
UniProt A0A8C2VCV5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Nfu1  NFU1 iron-sulfur cluster scaffold    NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED