Cav3 (caveolin 3) - Rat Genome Database

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Gene: Cav3 (caveolin 3) Chinchilla lanigera
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Symbol: Cav3
Name: caveolin 3
RGD ID: 9064143
Description: ENCODES a protein that exhibits alpha-tubulin binding (ortholog); calcium channel regulator activity (ortholog); connexin binding (ortholog); INVOLVED IN actin filament organization (ortholog); cardiac muscle cell development (ortholog); caveola assembly (ortholog); PARTICIPATES IN platelet-derived growth factor signaling pathway; ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy (ortholog); Cardiomegaly (ortholog); cardiomyopathy (ortholog); FOUND IN caveola (ortholog); cell surface (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: caveolin-3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955561325,944 - 335,914 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955561326,008 - 335,911 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin filament organization  (ISO)
cardiac muscle cell development  (ISO)
caveola assembly  (ISO)
cell differentiation  (ISO)
cellular response to organonitrogen compound  (ISO)
cholesterol homeostasis  (ISO)
cytoplasmic microtubule organization  (ISO)
detection of muscle stretch  (ISO)
endocytosis  (ISO)
glucose homeostasis  (ISO)
heart trabecula formation  (ISO)
membrane raft organization  (ISO)
myoblast fusion  (ISO)
myotube differentiation  (ISO)
negative regulation of calcium ion transport  (ISO)
negative regulation of cardiac muscle hypertrophy  (ISO)
negative regulation of cell growth involved in cardiac muscle cell development  (ISO)
negative regulation of cell size  (ISO)
negative regulation of MAP kinase activity  (ISO)
negative regulation of MAPK cascade  (ISO)
negative regulation of membrane depolarization during cardiac muscle cell action potential  (ISO)
negative regulation of nitric-oxide synthase activity  (ISO)
negative regulation of potassium ion transmembrane transport  (ISO)
negative regulation of potassium ion transmembrane transporter activity  (ISO)
negative regulation of protein kinase activity  (ISO)
negative regulation of sarcomere organization  (ISO)
nucleus localization  (ISO)
plasma membrane organization  (ISO)
plasma membrane repair  (ISO)
positive regulation of caveolin-mediated endocytosis  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of microtubule polymerization  (ISO)
positive regulation of myotube differentiation  (ISO)
protein localization  (ISO)
protein localization to plasma membrane  (ISO)
regulation of branching involved in mammary gland duct morphogenesis  (ISO)
regulation of calcium ion import  (ISO)
regulation of calcium ion transmembrane transporter activity  (ISO)
regulation of calcium ion transport  (ISO)
regulation of cardiac muscle cell action potential involved in regulation of contraction  (ISO)
regulation of cardiac muscle contraction  (ISO)
regulation of heart contraction  (ISO)
regulation of heart rate  (ISO)
regulation of membrane depolarization during cardiac muscle cell action potential  (ISO)
regulation of membrane potential  (ISO)
regulation of nerve growth factor receptor activity  (ISO)
regulation of p38MAPK cascade  (ISO)
regulation of protein kinase B signaling  (ISO)
regulation of signal transduction by receptor internalization  (ISO)
regulation of skeletal muscle contraction  (ISO)
regulation of sodium ion transmembrane transporter activity  (ISO)
regulation of transforming growth factor beta receptor signaling pathway  (ISO)
regulation of ventricular cardiac muscle cell membrane depolarization  (ISO)
regulation of ventricular cardiac muscle cell membrane repolarization  (ISO)
response to hypoxia  (ISO)
response to ischemia  (ISO)
triglyceride metabolic process  (ISO)
ventricular cardiac muscle cell action potential  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Cav3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955561325,944 - 335,914 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955561326,008 - 335,911 (+)NCBIChiLan1.0ChiLan1.0
CAV3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl38,733,802 - 8,841,808 (+)EnsemblGRCh38hg38GRCh38
GRCh3838,733,802 - 8,746,758 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3738,775,488 - 8,788,444 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3638,750,496 - 8,763,451 (+)NCBINCBI36hg18NCBI36
Build 3438,750,495 - 8,763,450NCBI
Celera38,710,271 - 8,723,238 (+)NCBI
Cytogenetic Map3p25.3NCBI
HuRef38,709,553 - 8,722,499 (+)NCBIHuRef
CHM1_138,725,885 - 8,738,871 (+)NCBICHM1_1
Cav3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396112,436,466 - 112,449,833 (+)NCBIGRCm39mm39
GRCm39 Ensembl6112,436,466 - 112,449,833 (+)Ensembl
GRCm386112,459,505 - 112,472,872 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6112,459,505 - 112,472,872 (+)EnsemblGRCm38mm10GRCm38
MGSCv376112,409,499 - 112,422,866 (+)NCBIGRCm37mm9NCBIm37
MGSCv366112,425,278 - 112,438,649 (+)NCBImm8
Celera6114,297,536 - 114,310,896 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map652.26NCBI
Cav3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24145,582,168 - 145,598,142 (+)NCBI
Rnor_6.0 Ensembl4144,382,945 - 144,398,917 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04144,382,945 - 144,398,919 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04207,683,202 - 207,699,176 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44148,294,428 - 148,310,380 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14148,539,268 - 148,555,221 (+)NCBI
Celera4134,152,488 - 134,168,462 (+)NCBICelera
Cytogenetic Map4q41NCBI
CAV3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.138,928,069 - 8,940,942 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl38,928,069 - 8,940,942 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v038,684,829 - 8,697,731 (+)NCBIMhudiblu_PPA_v0panPan3
CAV3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1209,384,901 - 9,398,055 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl209,384,901 - 9,401,196 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha209,418,382 - 9,431,544 (-)NCBI
ROS_Cfam_1.0209,414,987 - 9,428,087 (-)NCBI
UMICH_Zoey_3.1209,136,869 - 9,150,024 (-)NCBI
UNSW_CanFamBas_1.0209,481,732 - 9,494,836 (-)NCBI
UU_Cfam_GSD_1.0209,455,880 - 9,468,982 (-)NCBI
Cav3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494214,631,527 - 14,644,827 (+)NCBI
SpeTri2.0NW_0049366024,264,896 - 4,278,160 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAV3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1365,117,776 - 65,134,066 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11365,117,868 - 65,130,886 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21372,400,156 - 72,412,174 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CAV3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12244,726,597 - 44,740,456 (+)NCBI
Vero_WHO_p1.0NW_023666041121,826,639 - 121,839,504 (-)NCBI
Cav3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247313,348,172 - 3,363,772 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000002423   ⟹   ENSCLAP00000002372
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955561325,944 - 335,914 (+)Ensembl
RefSeq Acc Id: XM_005412999   ⟹   XP_005413056
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955561326,008 - 335,911 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005413056 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005413056   ⟸   XM_005412999
- Sequence:
RefSeq Acc Id: ENSCLAP00000002372   ⟸   ENSCLAT00000002423


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001721 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000002372 ENTREZGENE
Ensembl Transcript ENSCLAT00000002423 ENTREZGENE
NCBI Gene Cav3 ENTREZGENE