Inpp4a (inositol polyphosphate-4-phosphatase type I A) - Rat Genome Database

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Gene: Inpp4a (inositol polyphosphate-4-phosphatase type I A) Chinchilla lanigera
Analyze
Symbol: Inpp4a
Name: inositol polyphosphate-4-phosphatase type I A
RGD ID: 9062800
Description: INVOLVED IN regulation of postsynaptic membrane neurotransmitter receptor levels (ortholog); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; ASSOCIATED WITH autosomal dominant dyskeratosis congenita 1 (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN cytoplasm (ortholog); glutamatergic synapse (ortholog); nuclear membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inositol polyphosphate-4-phosphatase, type I, 107kDa; type I inositol 3,4-bisphosphate 4-phosphatase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554704,930,568 - 5,040,383 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554704,930,568 - 5,040,153 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Inpp4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554704,930,568 - 5,040,383 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554704,930,568 - 5,040,153 (+)NCBIChiLan1.0ChiLan1.0
INPP4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38298,444,587 - 98,594,392 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl298,444,854 - 98,594,392 (+)EnsemblGRCh38hg38GRCh38
GRCh37299,061,050 - 99,210,855 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36298,501,857 - 98,570,614 (+)NCBINCBI36Build 36hg18NCBI36
Build 34298,519,930 - 98,662,684NCBI
Celera293,265,040 - 93,411,219 (+)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef292,826,490 - 92,972,083 (+)NCBIHuRef
CHM1_1299,065,634 - 99,211,815 (+)NCBICHM1_1
T2T-CHM13v2.0298,902,886 - 99,052,718 (+)NCBIT2T-CHM13v2.0
Inpp4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39137,338,908 - 37,449,821 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl137,338,946 - 37,449,817 (+)EnsemblGRCm39 Ensembl
GRCm38137,299,827 - 37,410,740 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl137,299,865 - 37,410,736 (+)EnsemblGRCm38mm10GRCm38
MGSCv37137,356,738 - 37,467,581 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36137,302,465 - 37,352,805 (+)NCBIMGSCv36mm8
Celera137,079,390 - 37,192,754 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map115.46NCBI
Inpp4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8947,024,064 - 47,142,391 (+)NCBIGRCr8
mRatBN7.2939,528,245 - 39,650,574 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl939,528,674 - 39,646,581 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx948,024,733 - 48,142,652 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0953,147,494 - 53,265,400 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0951,429,369 - 51,547,271 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0943,889,887 - 44,006,593 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl943,889,473 - 44,004,325 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0943,533,507 - 43,707,953 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4936,238,645 - 36,356,933 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1936,240,058 - 36,358,347 (+)NCBI
Celera937,284,544 - 37,400,878 (+)NCBICelera
Cytogenetic Map9q21NCBI
INPP4A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21229,853,793 - 29,999,903 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A29,857,185 - 30,002,660 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A100,720,587 - 100,867,228 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A99,355,307 - 99,499,350 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A99,428,904 - 99,499,350 (+)Ensemblpanpan1.1panPan2
INPP4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11044,086,533 - 44,221,225 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1044,089,025 - 44,145,506 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1044,008,800 - 44,143,763 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01044,959,356 - 45,094,368 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1044,959,356 - 45,094,231 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11044,669,735 - 44,804,682 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01044,960,705 - 45,095,469 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01045,136,428 - 45,271,376 (-)NCBIUU_Cfam_GSD_1.0
Inpp4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629284,307,312 - 84,439,129 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367441,629,438 - 1,693,141 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367441,629,432 - 1,692,069 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INPP4A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl355,711,031 - 55,834,367 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1355,711,025 - 55,779,579 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2358,266,124 - 58,307,943 (-)NCBISscrofa10.2Sscrofa10.2susScr3
INPP4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1142,161,649 - 2,306,023 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl142,235,510 - 2,302,858 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041169,681,423 - 169,826,862 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Inpp4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247493,574,625 - 3,632,581 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247493,508,135 - 3,632,581 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005400714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005400715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005400718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005400720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005400722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013522723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013522724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013522726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013522727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013522728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013522729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013522730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013522732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01052741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01052742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBDF01050934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCLAT00000020071   ⟹   ENSCLAP00000019878
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554704,930,568 - 5,039,088 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000020072   ⟹   ENSCLAP00000019879
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554704,930,568 - 5,039,088 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000020073   ⟹   ENSCLAP00000019880
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554704,951,413 - 5,040,153 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000020074   ⟹   ENSCLAP00000019881
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554704,951,414 - 5,040,383 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000020075   ⟹   ENSCLAP00000019882
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554704,986,750 - 5,040,383 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000020076   ⟹   ENSCLAP00000019883
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554704,987,663 - 5,037,770 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000020077   ⟹   ENSCLAP00000019884
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554704,987,663 - 5,033,146 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000020078   ⟹   ENSCLAP00000019885
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554705,003,881 - 5,033,146 (+)Ensembl
RefSeq Acc Id: XM_005400714   ⟹   XP_005400771
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554704,951,414 - 5,040,153 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005400715   ⟹   XP_005400772
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554704,951,412 - 5,037,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005400718   ⟹   XP_005400775
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554704,951,412 - 5,037,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005400720   ⟹   XP_005400777
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554704,951,413 - 5,040,153 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005400722   ⟹   XP_005400779
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554704,951,414 - 5,040,153 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522723   ⟹   XP_013378177
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554704,951,412 - 5,037,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522724   ⟹   XP_013378178
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554704,964,666 - 5,037,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522726   ⟹   XP_013378180
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554704,930,568 - 5,037,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522727   ⟹   XP_013378181
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554704,930,821 - 5,037,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522728   ⟹   XP_013378182
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554704,951,413 - 5,037,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522729   ⟹   XP_013378183
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554704,951,412 - 5,037,570 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522730   ⟹   XP_013378184
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554704,951,413 - 5,040,153 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013522732   ⟹   XP_013378186
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554704,990,412 - 5,037,570 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005400772   ⟸   XM_005400715
- Peptide Label: isoform X6
- UniProtKB: A0A8C2VUU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005400775   ⟸   XM_005400718
- Peptide Label: isoform X7
- UniProtKB: A0A8C2VUU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005400777   ⟸   XM_005400720
- Peptide Label: isoform X8
- UniProtKB: A0A8C2VZS1 (UniProtKB/TrEMBL),   A0A8C2VSH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005400771   ⟸   XM_005400714
- Peptide Label: isoform X5
- UniProtKB: A0A8C2VWH7 (UniProtKB/TrEMBL),   A0A8C2VSH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005400779   ⟸   XM_005400722
- Peptide Label: isoform X9
- UniProtKB: A0A8C2VUK0 (UniProtKB/TrEMBL),   A0A8C2VSH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013378180   ⟸   XM_013522726
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VUU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013378181   ⟸   XM_013522727
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VUU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013378177   ⟸   XM_013522723
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VUU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013378183   ⟸   XM_013522729
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VUU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013378184   ⟸   XM_013522730
- Peptide Label: isoform X4
- UniProtKB: A0A8C2VSH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013378182   ⟸   XM_013522728
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VUU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013378178   ⟸   XM_013522724
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VUU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013378186   ⟸   XM_013522732
- Peptide Label: isoform X10
- UniProtKB: A0A8C2VUU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000019878   ⟸   ENSCLAT00000020071
RefSeq Acc Id: ENSCLAP00000019879   ⟸   ENSCLAT00000020072
RefSeq Acc Id: ENSCLAP00000019880   ⟸   ENSCLAT00000020073
RefSeq Acc Id: ENSCLAP00000019881   ⟸   ENSCLAT00000020074
RefSeq Acc Id: ENSCLAP00000019882   ⟸   ENSCLAT00000020075
RefSeq Acc Id: ENSCLAP00000019883   ⟸   ENSCLAT00000020076
RefSeq Acc Id: ENSCLAP00000019884   ⟸   ENSCLAT00000020077
RefSeq Acc Id: ENSCLAP00000019885   ⟸   ENSCLAT00000020078
Protein Domains
C2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013632 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000020071.1 UniProtKB/TrEMBL
  ENSCLAT00000020072.1 UniProtKB/TrEMBL
  ENSCLAT00000020073 ENTREZGENE
  ENSCLAT00000020073.1 UniProtKB/TrEMBL
  ENSCLAT00000020074 ENTREZGENE
  ENSCLAT00000020074.1 UniProtKB/TrEMBL
  ENSCLAT00000020075 ENTREZGENE
  ENSCLAT00000020075.1 UniProtKB/TrEMBL
  ENSCLAT00000020076.1 UniProtKB/TrEMBL
  ENSCLAT00000020077 ENTREZGENE
  ENSCLAT00000020077.1 UniProtKB/TrEMBL
  ENSCLAT00000020078.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  INPP4 UniProtKB/TrEMBL
NCBI Gene Inpp4a ENTREZGENE
PANTHER INOSITOL POLYPHOSPHATE-4-PHOSPHATASE TYPE I A UniProtKB/TrEMBL
  PTHR12187 UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A8C2VSH5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VUK0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VUU5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VWH7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VXH0_CHILA UniProtKB/TrEMBL
  A0A8C2VZC5_CHILA UniProtKB/TrEMBL
  A0A8C2VZS1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Inpp4a  inositol polyphosphate-4-phosphatase type I A    inositol polyphosphate-4-phosphatase, type I, 107kDa  Symbol and/or name change 5135510 APPROVED