Ric8a (RIC8 guanine nucleotide exchange factor A) - Rat Genome Database

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Gene: Ric8a (RIC8 guanine nucleotide exchange factor A) Chinchilla lanigera
Analyze
Symbol: Ric8a
Name: RIC8 guanine nucleotide exchange factor A
RGD ID: 9062780
Description: ENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); GTPase activator activity (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); basement membrane organization (ortholog); cell migration involved in gastrulation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: synembryn-A
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,827,004 - 11,833,162 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,827,004 - 11,833,495 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ric8a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,827,004 - 11,833,162 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,827,004 - 11,833,495 (-)NCBIChiLan1.0ChiLan1.0
RIC8A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811207,708 - 215,113 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11207,708 - 215,113 (+)EnsemblGRCh38hg38GRCh38
GRCh3711207,708 - 215,113 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611198,530 - 205,113 (+)NCBINCBI36Build 36hg18NCBI36
Celera11343,749 - 350,332 (-)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef1128,547 - 35,130 (+)NCBIHuRef
CHM1_111207,204 - 213,787 (+)NCBICHM1_1
T2T-CHM13v2.011248,906 - 256,311 (+)NCBIT2T-CHM13v2.0
Ric8a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397140,437,310 - 140,443,644 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7140,436,870 - 140,444,285 (+)EnsemblGRCm39 Ensembl
GRCm387140,857,397 - 140,863,731 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7140,856,957 - 140,864,372 (+)EnsemblGRCm38mm10GRCm38
MGSCv377148,043,296 - 148,049,630 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367140,708,717 - 140,715,051 (+)NCBIMGSCv36mm8
Celera7140,649,681 - 140,656,018 (+)NCBICelera
Cytogenetic Map7F4NCBI
cM Map786.06NCBI
Ric8a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81205,364,796 - 205,371,102 (+)NCBIGRCr8
mRatBN7.21195,935,162 - 195,941,469 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1195,935,349 - 195,941,467 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1204,287,626 - 204,293,929 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01211,414,534 - 211,420,838 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01204,088,386 - 204,094,690 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01213,606,599 - 213,612,905 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,606,599 - 213,612,904 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01220,531,948 - 220,538,536 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,014,483 - 201,020,790 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11201,164,714 - 201,170,146 (+)NCBI
Celera1193,579,108 - 193,585,413 (+)NCBICelera
Cytogenetic Map1q41NCBI
RIC8A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v292,574,819 - 2,582,645 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1111,730,133 - 1,738,008 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011203,317 - 210,135 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111248,881 - 255,274 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11248,880 - 255,269 (+)Ensemblpanpan1.1panPan2
RIC8A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11825,363,031 - 25,368,645 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1825,362,875 - 25,368,378 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1825,012,985 - 25,018,594 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01825,889,581 - 25,895,184 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1825,889,427 - 25,902,180 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11825,457,590 - 25,463,198 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01825,102,367 - 25,107,976 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01825,715,214 - 25,720,830 (+)NCBIUU_Cfam_GSD_1.0
Ric8a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494757,369 - 62,720 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493688856,811 - 63,776 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493688857,212 - 62,722 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIC8A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl232,215 - 39,360 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1232,135 - 37,682 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22162,187,001 - 162,192,480 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RIC8A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1118,597 - 25,398 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl119,013 - 25,473 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603897,033,852 - 97,040,311 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ric8a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476622,234,484 - 22,240,940 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476622,234,484 - 22,240,874 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000007393   ⟹   ENSCLAP00000007279
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547611,827,004 - 11,833,162 (-)Ensembl
RefSeq Acc Id: XM_005401889   ⟹   XP_005401946
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547611,827,006 - 11,833,495 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005401890   ⟹   XP_005401947
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547611,827,006 - 11,833,495 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013502915   ⟹   XP_013358369
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547611,827,004 - 11,833,162 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005401946 (Get FASTA)   NCBI Sequence Viewer  
  XP_005401947 (Get FASTA)   NCBI Sequence Viewer  
  XP_013358369 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000007279
  ENSCLAP00000007279.1
RefSeq Acc Id: XP_005401947   ⟸   XM_005401890
- UniProtKB: A0A8C2V2S6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005401946   ⟸   XM_005401889
- UniProtKB: A0A8C2V2S6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013358369   ⟸   XM_013502915
- UniProtKB: A0A8C2V2S6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000007279   ⟸   ENSCLAT00000007393


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005117 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007393 ENTREZGENE
  ENSCLAT00000007393.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Gua_nucleotide_exch_fac_Ric8 UniProtKB/TrEMBL
  Synembryn UniProtKB/TrEMBL
NCBI Gene Ric8a ENTREZGENE
PANTHER PTHR12425 UniProtKB/TrEMBL
  SYNEMBRYN-A UniProtKB/TrEMBL
Pfam Ric8 UniProtKB/TrEMBL
PRINTS SYNEMBRYN UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A8C2V2S6 ENTREZGENE, UniProtKB/TrEMBL