Erc2 (ELKS/RAB6-interacting/CAST family member 2) - Rat Genome Database

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Gene: Erc2 (ELKS/RAB6-interacting/CAST family member 2) Chinchilla lanigera
Analyze
Symbol: Erc2
Name: ELKS/RAB6-interacting/CAST family member 2
RGD ID: 9057826
Description: ENCODES a protein that exhibits PDZ domain binding (ortholog); protein-containing complex binding (ortholog); structural constituent of presynaptic active zone (ortholog); INVOLVED IN maintenance of presynaptic active zone structure (ortholog); regulation of calcium-dependent activation of synaptic vesicle fusion (ortholog); regulation of presynaptic cytosolic calcium ion concentration (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog); Golgi-associated vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ERC protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554305,513,662 - 6,308,882 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554305,345,191 - 6,308,909 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Erc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554305,513,662 - 6,308,882 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554305,345,191 - 6,308,909 (-)NCBIChiLan1.0ChiLan1.0
ERC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38355,508,311 - 56,468,467 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl355,508,311 - 56,469,095 (-)EnsemblGRCh38hg38GRCh38
GRCh37355,542,339 - 56,502,495 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36355,517,376 - 56,477,431 (-)NCBINCBI36Build 36hg18NCBI36
Celera355,509,269 - 56,468,649 (-)NCBICelera
Cytogenetic Map3p14.3NCBI
HuRef355,591,133 - 56,551,243 (-)NCBIHuRef
CHM1_1355,493,671 - 56,453,566 (-)NCBICHM1_1
T2T-CHM13v2.0355,542,510 - 56,508,891 (-)NCBIT2T-CHM13v2.0
Erc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391427,344,232 - 28,200,494 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1427,344,385 - 28,200,494 (+)EnsemblGRCm39 Ensembl
GRCm381427,622,275 - 28,478,537 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1427,622,428 - 28,478,537 (+)EnsemblGRCm38mm10GRCm38
MGSCv371428,435,628 - 29,291,723 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361426,449,326 - 27,305,403 (+)NCBIMGSCv36mm8
Celera1423,854,528 - 24,727,160 (+)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1416.51NCBI
Erc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8162,819,399 - 3,680,258 (+)NCBIGRCr8
mRatBN7.2162,812,712 - 3,673,624 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl162,848,620 - 3,670,776 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx162,819,340 - 3,680,212 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0163,965,020 - 4,825,629 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0162,824,168 - 3,685,138 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0163,258,580 - 4,283,592 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl163,293,599 - 3,679,222 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0163,260,419 - 4,388,774 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4162,932,781 - 3,596,299 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1162,932,780 - 3,596,297 (+)NCBI
Celera162,811,369 - 3,459,316 (+)NCBICelera
Cytogenetic Map16p16NCBI
ERC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2255,491,457 - 56,468,006 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1355,496,228 - 56,472,777 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0355,438,875 - 56,417,072 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1356,659,377 - 57,599,384 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl356,836,941 - 57,599,248 (-)Ensemblpanpan1.1panPan2
ERC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12033,842,753 - 34,748,038 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2033,842,753 - 34,746,491 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2033,769,262 - 34,672,553 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02034,114,565 - 35,020,292 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2034,114,216 - 35,020,299 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12033,558,663 - 34,463,362 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02033,918,155 - 34,823,551 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02034,092,812 - 35,039,347 (+)NCBIUU_Cfam_GSD_1.0
Erc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118172,937,212 - 173,811,690 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364736,075,769 - 6,950,263 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364736,075,811 - 6,532,671 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1337,388,517 - 38,367,504 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11337,388,513 - 38,367,512 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21341,281,049 - 41,624,117 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ERC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12216,851,862 - 17,817,504 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2217,034,445 - 17,817,522 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041149,054,724 - 150,028,608 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Erc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624822756,550 - 1,807,175 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624822756,532 - 1,806,129 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005387385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005387388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013515684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013515685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013515686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013515687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013515688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013515689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013515690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001234567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01029260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01029285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBDI01215309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCLAT00000007973   ⟹   ENSCLAP00000007853
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554305,513,662 - 6,308,882 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000007974   ⟹   ENSCLAP00000007854
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554305,513,662 - 6,307,809 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000007975   ⟹   ENSCLAP00000007855
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554305,513,701 - 6,277,554 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000007976   ⟹   ENSCLAP00000007856
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554305,513,701 - 6,277,554 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000007977   ⟹   ENSCLAP00000007857
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554306,013,849 - 6,016,850 (-)Ensembl
RefSeq Acc Id: XM_005387385   ⟹   XP_005387442
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554305,345,191 - 6,308,909 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005387388   ⟹   XP_005387445
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554305,345,191 - 6,308,909 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515684   ⟹   XP_013371138
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554305,345,191 - 6,308,909 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515685   ⟹   XP_013371139
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554305,345,191 - 6,307,760 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515686   ⟹   XP_013371140
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554305,345,191 - 6,308,909 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515687   ⟹   XP_013371141
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554305,345,191 - 6,308,909 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515688   ⟹   XP_013371142
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554305,345,191 - 6,308,909 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515689   ⟹   XP_013371143
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554305,345,191 - 6,308,909 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515690   ⟹   XP_013371144
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554305,348,075 - 6,308,909 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001234567
Type: NON-CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554305,348,072 - 6,308,909 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005387445   ⟸   XM_005387388
- Peptide Label: isoform X7
- UniProtKB: A0A8C2V519 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005387442   ⟸   XM_005387385
- Peptide Label: isoform X5
- UniProtKB: A0A8C2V422 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013371142   ⟸   XM_013515688
- Peptide Label: isoform X4
- UniProtKB: A0A8C2V519 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013371143   ⟸   XM_013515689
- Peptide Label: isoform X6
- UniProtKB: A0A8C2UZ11 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013371141   ⟸   XM_013515687
- Peptide Label: isoform X3
- UniProtKB: A0A8C2UZ11 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013371140   ⟸   XM_013515686
- Peptide Label: isoform X2
- UniProtKB: A0A8C2V519 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013371138   ⟸   XM_013515684
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V422 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013371139   ⟸   XM_013515685
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V422 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013371144   ⟸   XM_013515690
- Peptide Label: isoform X8
- UniProtKB: A0A8C2V422 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000007853   ⟸   ENSCLAT00000007973
RefSeq Acc Id: ENSCLAP00000007854   ⟸   ENSCLAT00000007974
RefSeq Acc Id: ENSCLAP00000007855   ⟸   ENSCLAT00000007975
RefSeq Acc Id: ENSCLAP00000007856   ⟸   ENSCLAT00000007976
RefSeq Acc Id: ENSCLAP00000007857   ⟸   ENSCLAT00000007977


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005508 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007973 ENTREZGENE
  ENSCLAT00000007973.1 UniProtKB/TrEMBL
  ENSCLAT00000007974.1 UniProtKB/TrEMBL
  ENSCLAT00000007975.1 UniProtKB/TrEMBL
  ENSCLAT00000007976.1 UniProtKB/TrEMBL
  ENSCLAT00000007977.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.1490 UniProtKB/TrEMBL
InterPro ELKS/CAST UniProtKB/TrEMBL
NCBI Gene Erc2 ENTREZGENE
PANTHER ELKS/RAB6-INTERACTING/CAST PROTEIN UniProtKB/TrEMBL
  PTHR18861:SF3 UniProtKB/TrEMBL
Pfam Cast UniProtKB/TrEMBL
Superfamily-SCOP Tropomyosin UniProtKB/TrEMBL
UniProt A0A8C2UZ11 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UZ13_CHILA UniProtKB/TrEMBL
  A0A8C2V422 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2V519 ENTREZGENE, UniProtKB/TrEMBL