Cct3 (chaperonin containing TCP1 subunit 3)

Gene: Cct3 (chaperonin containing TCP1 subunit 3) Chinchilla lanigera

Analyze

Symbol:

Cct3

Name:

chaperonin containing TCP1 subunit 3

RGD ID:

9057612

Description:

ENCODES a protein that exhibits protein folding chaperone (ortholog); INVOLVED IN binding of sperm to zona pellucida (ortholog); chaperone-mediated protein folding (ortholog); positive regulation of establishment of protein localization to telomere (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); Chemical and Drug Induced Liver Injury (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN cell body (ortholog); chaperonin-containing T-complex (ortholog); microtubule (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

chaperonin containing TCP1, subunit 3 (gamma); T-complex protein 1 subunit gamma

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955545	2,444,988 - 2,461,113 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955545	2,444,988 - 2,460,976 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease type 2 (ISO)

Chemical and Drug Induced Liver Injury (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

human immunodeficiency virus infectious disease (ISO)

immunodeficiency 42 (ISO)

MHC class II deficiency (ISO)

parathyroid carcinoma (ISO)

severe congenital neutropenia 3 (ISO)

severe congenital neutropenia 5 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

binding of sperm to zona pellucida (ISO)

chaperone-mediated protein folding (ISO)

positive regulation of establishment of protein localization to telomere (ISO)

positive regulation of protein localization to Cajal body (ISO)

positive regulation of telomerase RNA localization to Cajal body (ISO)

positive regulation of telomere maintenance via telomerase (ISO)

protein folding (ISO)

protein stabilization (ISO)

Cellular Component

cell body (ISO)

chaperonin-containing T-complex (ISO)

microtubule (ISO)

zona pellucida receptor complex (ISO)

Molecular Function

protein binding (ISO)

protein folding chaperone (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Cct3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955545	2,444,988 - 2,461,113 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955545	2,444,988 - 2,460,976 (-)	NCBI	ChiLan1.0	ChiLan1.0

CCT3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	156,308,968 - 156,338,292 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	156,308,968 - 156,367,873 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	156,278,759 - 156,308,083 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	154,545,376 - 154,574,819 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	153,091,832 - 153,121,121	NCBI
Celera	1	129,351,733 - 129,381,131 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI
HuRef	1	127,638,812 - 127,668,494 (-)	NCBI		HuRef
CHM1_1	1	157,674,664 - 157,704,561 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	155,447,437 - 155,476,903 (-)	NCBI		T2T-CHM13v2.0

Cct3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	88,204,442 - 88,229,073 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	88,204,423 - 88,229,074 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	88,297,135 - 88,321,766 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	88,297,116 - 88,321,767 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	88,101,057 - 88,125,688 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	88,383,062 - 88,407,693 (+)	NCBI		MGSCv36	mm8
Celera	3	88,336,705 - 88,361,340 (+)	NCBI		Celera
Cytogenetic Map	3	F1	NCBI
cM Map	3	38.79	NCBI

Cct3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	176,063,529 - 176,088,180 (+)	NCBI		GRCr8
mRatBN7.2	2	173,765,701 - 173,790,353 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	173,765,698 - 173,790,757 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	180,910,314 - 180,934,758 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	178,932,672 - 178,957,116 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	173,532,533 - 173,557,196 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	187,669,051 - 187,693,610 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	187,668,796 - 187,693,610 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	207,072,068 - 207,096,553 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	180,381,044 - 180,434,152 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	180,331,149 - 180,384,258 (+)	NCBI
Celera	2	167,711,584 - 167,735,276 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

CCT3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	93,508,565 - 93,536,333 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	93,240,518 - 93,268,250 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	131,652,058 - 131,679,802 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	135,482,012 - 135,508,983 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	135,481,427 - 135,508,983 (-)	Ensembl	panpan1.1		panPan2

CCT3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	41,566,274 - 41,583,903 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	41,566,292 - 41,584,863 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	41,054,446 - 41,072,072 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	41,431,013 - 41,448,650 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	41,431,096 - 41,449,272 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	41,212,433 - 41,230,036 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	41,265,635 - 41,283,249 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	41,549,686 - 41,567,311 (+)	NCBI		UU_Cfam_GSD_1.0

Cct3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	26,506,956 - 26,523,883 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	5,537,015 - 5,554,384 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	5,537,338 - 5,554,384 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCT3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	93,733,918 - 93,753,340 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	93,733,967 - 93,753,340 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	102,435,570 - 102,453,406 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CCT3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	7,518,729 - 7,545,296 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	7,518,846 - 7,545,677 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	6,819,515 - 6,846,680 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cct3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624885	1,575,562 - 1,592,594 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624885	1,575,560 - 1,592,540 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005411673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01071901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01010937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000006261 ⟹ ENSCLAP00000006158

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955545	2,444,988 - 2,461,113 (-)	Ensembl

RefSeq Acc Id:

ENSCLAT00000006262 ⟹ ENSCLAP00000006159

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955545	2,445,219 - 2,460,852 (-)	Ensembl

RefSeq Acc Id:

XM_005411673 ⟹ XP_005411730

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955545	2,444,988 - 2,460,976 (-)	NCBI

Sequence:

show sequence

TAGCGGGTTTAGGTGTCAGCCCTGAGGAGGCAGCGTTTTCTGGGCTTGTCCCCGTTTCTCTGTC
TCTCCAGAAGATTCTGCCGGTTCTCCCTGCTCTGGGTACCTGGCTCTGCAACGCGCCGCCATGA
TGGGCCACCGTCCCGTGCTCGTGCTCAGCCAAAATACAAAGCGTGAATCTGGAAGAAAAGTTCA
ATCTGGAAACATCAATGCTGCTAAGACTATTGCAGATATCATTCGAACATGTTTGGGACCCAAG
TCCATGATGAAGATGCTTTTGGATCCAATGGGAGGCATCGTGATGACCAATGATGGCAATGCCA
TTCTTCGAGAGATTCAAGTCCAGCATCCAGCAGCCAAGTCAATGATTGAAATTAGCCGGACACA
AGATGAAGAGGTTGGAGATGGGACCACATCAGTAATTATTCTTGCGGGAGAGATGTTGTCTGTG
GCTGAGCACTTCCTGGAGCAACAGATGCACCCAACAGTGGTGATCAGTGCATACCGAAAAGCGC
TGGATGATATGATCAGCACTCTAAAGAAAATCAGCACCCCTGTTGACGTCAATAACCGTGATAT
GATGCTAAACATCATCAATAGCTCCATTACTACCAAAGCAATCAGTTGGTGGTCTTCTTTGGCT
TGTAATATTGCCCTGGATGCTGTCAAGACTGTACAGTTTGAGGAAAATGGTCGGAAAGAAATCG
ACATCAAGAAATACGCAAAAGTGGAAAAGATACCTGGGGGCATCATTGAAGACTCATGTGTCCT
GCGTGGAGTCATGATTAACAAGGATGTGACCCATTCACGAATGAGGCGCTATATAAAGAATCCT
CGAATTGTGCTGCTGGATTCATCTCTCGAGTACAAGAAAGGAGAAAGCCAGACTGACATTGAGA
TTACACGAGAGGAAGACTTTGCCCGAATCCTCCAGATGGAAGAAGAGTACATCCAGCAGCTCTG
CGAGGACATCATCCAGTTGAAGCCCGACGTGGTCATCACAGAAAAGGGCATTTCAGATTTAGCT
CAGCACTACCTCTTGCGGGCCAATATCACAGCCATCCGTAGAGTTCGAAAGACAGACAATAATC
GGATAGCTAGAGCCTGTGGGGCCCGGATAGTTAGCAGACCGGAAGAGCTGAGAGAAGATGATGT
TGGGACAGGAGCAGGCCTGCTGGAAATCAAGAAAATTGGAGACGAGTACTTTACATTCATCACT
GAGTGCAAAGACCCCAAGGCCTGTACCATCCTCCTCAGAGGAGCCAGCAAAGAAATTCTCTCGG
AAGTAGAGCGCAACCTACAGGACGCTATGCAAGTGTGCCGCAACGTGCTCCTGGACCCTCAGCT
GGTGCCAGGAGGTGGGGCCTCTGAGATGGCTGTGGCCCATGCCTTGACAGAAAAATCCAAGGCC
ATGACTGGCGTGGAGCAGTGGCCCTACAGGGCTGTAGCGCAGGCTCTGGAGGTCATCCCTCGCA
CACTCATCCAGAACTGTGGGGCCAGCACCATCCGCCTACTAACCTCTCTTCGGGCCAAACACAC
ACAGGAAGGCTGTGAGACCTGGGGTGTAAATGGAGAGACAGGGGCTTTGGTGGACATGAAGGAA
CTGGGCATATGGGAGCCTTTGGCTGTGAAGCTACAAACATACAAGACAGCAGTAGAGACGGCAG
TTTTGCTGCTGAGGATTGATGACATCGTCTCAGGCCACAAAAAGAAGGGTGATGATCAGAGCCG
GCAAGGTGGGGCTCCTGATCCTGGCCAGGAGTGAATGGTGGGCGAGGCGACTTCAGCACACAGA
CCAGCAGTCTCCCCTTTTCTTCAGCCAGTGTGCCAGGAACACTGTGCACGTCTTTGTTTGGAAG
GGATCAGGTTGAGGGGCAGTCCCCAGTACCGCTCTGTCCCAGCTCAGTTTGCAAAAGGCACTGA
CATGTAATTCTTCTCTATTGTAAGCTTTCCATTTAGTTTGCTTCCTATGATTAAATCTAAGTCA
TTTGAGATA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005411730	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000006158
	ENSCLAP00000006158.1
	ENSCLAP00000006159.1

RefSeq Acc Id:

XP_005411730 ⟸ XM_005411673

- UniProtKB:

A0A8C2UVS5 (UniProtKB/TrEMBL), A0A8C2UYL4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGN
AILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRK
ALDDMISTLKKISTPVDVNNRDMMLNIINSSITTKAISWWSSLACNIALDAVKTVQFEENGRKE
IDIKKYAKVEKIPGGIIEDSCVLRGVMINKDVTHSRMRRYIKNPRIVLLDSSLEYKKGESQTDI
EITREEDFARILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLLRANITAIRRVRKTDN
NRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITECKDPKACTILLRGASKEIL
SEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIP
RTLIQNCGASTIRLLTSLRAKHTQEGCETWGVNGETGALVDMKELGIWEPLAVKLQTYKTAVET
AVLLLRIDDIVSGHKKKGDDQSRQGGAPDPGQE

hide sequence

RefSeq Acc Id:

ENSCLAP00000006158 ⟸ ENSCLAT00000006261

RefSeq Acc Id:

ENSCLAP00000006159 ⟸ ENSCLAT00000006262

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000004359	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000006261	ENTREZGENE
	ENSCLAT00000006261.1	UniProtKB/TrEMBL
	ENSCLAT00000006262.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.560.10	UniProtKB/TrEMBL
	3.30.260.10	UniProtKB/TrEMBL
	3.50.7.10	UniProtKB/TrEMBL
InterPro	Chap_CCT_gamma	UniProtKB/TrEMBL
	Chaperone_TCP-1	UniProtKB/TrEMBL
	Chaperonin_TCP-1_CS	UniProtKB/TrEMBL
	Cpn60/GroEL/TCP-1	UniProtKB/TrEMBL
	GroEL-like_apical_dom_sf	UniProtKB/TrEMBL
	GROEL-like_equatorial_sf	UniProtKB/TrEMBL
	TCP-1-like_intermed_sf	UniProtKB/TrEMBL
NCBI Gene	Cct3	ENTREZGENE
PANTHER	PTHR11353	UniProtKB/TrEMBL
	T-COMPLEX PROTEIN 1 SUBUNIT GAMMA	UniProtKB/TrEMBL
Pfam	Cpn60_TCP1	UniProtKB/TrEMBL
PRINTS	TCOMPLEXTCP1	UniProtKB/TrEMBL
PROSITE	TCP1_1	UniProtKB/TrEMBL
	TCP1_2	UniProtKB/TrEMBL
	TCP1_3	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48592	UniProtKB/TrEMBL
	SSF52029	UniProtKB/TrEMBL
	SSF54849	UniProtKB/TrEMBL
UniProt	A0A8C2UVS5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2UYL4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Cct3	chaperonin containing TCP1 subunit 3		chaperonin containing TCP1, subunit 3 (gamma)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD