LOC102010850 (cytochrome P450 1A1)

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Gene: LOC102010850 (cytochrome P450 1A1) Chinchilla lanigera

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Symbol:

LOC102010850 (Ensembl: CYP1A1)

Name:

cytochrome P450 1A1 (Ensembl:cytochrome P450 family 1 subfamily A member 1)

RGD ID:

9056314

Description:

ENCODES a protein that exhibits arachidonate monooxygenase activity (ortholog); catalytic activity (ortholog); demethylase activity (ortholog); INVOLVED IN 9-cis-retinoic acid biosynthetic process (ortholog); amine metabolic process (ortholog); camera-type eye development (ortholog); PARTICIPATES IN gefitinib pharmacokinetics pathway; phase I biotransformation pathway via cytochrome P450; tamoxifen pharmacokinetics pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Lung Injury (ortholog); acute lymphoblastic leukemia (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955450	3,183,750 - 3,189,488 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955450	3,183,958 - 3,189,488 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute kidney failure (ISO)

Acute Lung Injury (ISO)

acute lymphoblastic leukemia (ISO)

acute myeloid leukemia (ISO)

allergic contact dermatitis (ISO)

allergic disease (ISO)

ankylosing spondylitis (ISO)

Arteritis (ISO)

asthma (ISO)

atopic dermatitis (ISO)

autism spectrum disorder (ISO)

Bardet-Biedl syndrome (ISO)

Behcet's disease (ISO)

biliary tract cancer (ISO)

Birth Weight (ISO)

Bloom syndrome (ISO)

Bradycardia (ISO)

breast cancer (ISO)

Breast Neoplasms (ISO)

bronchitis (ISO)

Brugada syndrome 8 (ISO)

Cardiac Fibrosis (ISO)

Cardiomegaly (ISO)

Chemical and Drug Induced Liver Injury (ISO)

Chronic Bronchitis (ISO)

Chronic Intermittent Hypoxia (ISO)

chronic myeloid leukemia (ISO)

chronic obstructive pulmonary disease (ISO)

clubfoot (ISO)

colitis (ISO)

colorectal cancer (ISO)

contact dermatitis (ISO)

cystic fibrosis (ISO)

diabetes mellitus (ISO)

Digestive System Neoplasms (ISO)

dilated cardiomyopathy (ISO)

Drug Eruptions (ISO)

end stage renal disease (ISO)

endometrial cancer (ISO)

endometriosis (ISO)

esophageal cancer (ISO)

esophagus squamous cell carcinoma (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Liver Neoplasms (ISO)

Fetal Growth Retardation (ISO)

gallbladder cancer (ISO)

Graves' disease (ISO)

Hamartoma (ISO)

head and neck cancer (ISO)

heart disease (ISO)

Hematuria (ISO)

hepatocellular carcinoma (ISO)

Hepatomegaly (ISO)

Hyperoxia (ISO)

Hyperoxic Lung Injury (ISO)

hypertension (ISO)

Hypertriglyceridemia (ISO)

hypertrophic cardiomyopathy (ISO)

hypospadias (ISO)

Inflammation (ISO)

Jaundice (ISO)

Keshan disease (ISO)

Kidney Neoplasms (ISO)

Liver Reperfusion Injury (ISO)

long QT syndrome (ISO)

lung cancer (ISO)

Lung Injury (ISO)

male infertility (ISO)

Metabolic Side Effects of Drugs and Substances (ISO)

Micronuclei, Chromosome-Defective (ISO)

multiple myeloma (ISO)

Nematode Infections (ISO)

nephritis (ISO)

Occupational Diseases (ISO)

oral cavity cancer (ISO)

oral squamous cell carcinoma (ISO)

PAPA syndrome (ISO)

Parkinson's disease (ISO)

Parkinsonism (ISO)

periodontitis (ISO)

peripheral vascular disease (ISO)

pneumonia (ISO)

polycystic ovary syndrome (ISO)

porphyria cutanea tarda (ISO)

Prenatal Exposure Delayed Effects (ISO)

prostate cancer (ISO)

Prostatic Neoplasms (ISO)

psoriasis (ISO)

psoriatic arthritis (ISO)

pulmonary hypertension (ISO)

Pulmonary Hypertension, Hypoxia-Induced (ISO)

reactive arthritis (ISO)

renal cell carcinoma (ISO)

schizophrenia (ISO)

Sepsis (ISO)

Sinus Tachycardia (ISO)

Sjogren's syndrome (ISO)

Spontaneous Abortions (ISO)

stomach cancer (ISO)

systemic lupus erythematosus (ISO)

type 2 diabetes mellitus (ISO)

urinary bladder cancer (ISO)

Ventricular Remodeling (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

9-cis-retinoic acid biosynthetic process (ISO)

amine metabolic process (ISO)

camera-type eye development (ISO)

cellular response to copper ion (ISO)

cellular response to organic cyclic compound (ISO)

coumarin metabolic process (ISO)

dibenzo-p-dioxin catabolic process (ISO)

dibenzo-p-dioxin metabolic process (ISO)

digestive tract development (ISO)

estrogen metabolic process (ISO)

fatty acid metabolic process (ISO)

flavonoid metabolic process (ISO)

hepatocyte differentiation (ISO)

hydrogen peroxide biosynthetic process (ISO)

insecticide metabolic process (ISO)

lipid hydroxylation (ISO)

liver development (ISO)

long-chain fatty acid metabolic process (ISO)

maternal process involved in parturition (ISO)

nitric oxide metabolic process (ISO)

phenol-containing compound metabolic process (ISO)

porphyrin-containing compound metabolic process (ISO)

positive regulation of G1/S transition of mitotic cell cycle (ISO)

response to 2,3,7,8-tetrachlorodibenzodioxine (ISO)

response to 3-methylcholanthrene (ISO)

response to Aroclor 1254 (ISO)

response to arsenic-containing substance (ISO)

response to diphenyl ether (ISO)

response to food (ISO)

response to genistein (ISO)

response to herbicide (ISO)

response to hyperoxia (ISO)

response to hypoxia (ISO)

response to immobilization stress (ISO)

response to iron(III) ion (ISO)

response to lipopolysaccharide (ISO)

response to nematode (ISO)

response to toxic substance (ISO)

response to vitamin A (ISO)

response to xenobiotic stimulus (ISO)

retinol metabolic process (ISO)

steroid metabolic process (ISO)

tissue remodeling (ISO)

toxin metabolic process (ISO)

xenobiotic metabolic process (ISO)

Cellular Component

mitochondrial inner membrane (ISO)

mitochondrion (ISO)

Molecular Function

arachidonate monooxygenase activity (ISO)

catalytic activity (ISO)

demethylase activity (ISO)

enzyme binding (ISO)

estrogen 16-alpha-hydroxylase activity (ISO)

estrogen 2-hydroxylase activity (ISO)

flavonoid 3'-monooxygenase activity (ISO)

Hsp70 protein binding (ISO)

Hsp90 protein binding (ISO)

long-chain fatty acid omega-1 hydroxylase activity (ISO)

long-chain fatty acid omega-hydroxylase activity (ISO)

monooxygenase activity (ISO)

oxidoreductase activity (ISO)

oxidoreductase activity, acting on diphenols and related substances as donors (ISO)

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (ISO)

protein binding (ISO)

steroid hydroxylase activity (ISO)

vitamin D 24-hydroxylase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

gefitinib pharmacokinetics pathway (ISO)

phase I biotransformation pathway via cytochrome P450 (ISO)

tamoxifen pharmacokinetics pathway (ISO)

tryptophan metabolic pathway (ISO)

warfarin pharmacokinetics pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LOC102010850
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955450	3,183,750 - 3,189,488 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955450	3,183,958 - 3,189,488 (+)	NCBI	ChiLan1.0	ChiLan1.0

CYP1A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	74,719,542 - 74,725,528 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	74,719,542 - 74,725,536 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	75,011,883 - 75,017,869 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	72,798,943 - 72,804,930 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	72,798,942 - 72,804,930	NCBI
Celera	15	51,961,906 - 51,967,900 (-)	NCBI		Celera
Cytogenetic Map	15	q24.1	NCBI
HuRef	15	51,809,772 - 51,815,766 (-)	NCBI		HuRef
CHM1_1	15	75,130,208 - 75,136,202 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	72,589,430 - 72,595,416 (-)	NCBI		T2T-CHM13v2.0

Cyp1a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	57,595,211 - 57,611,107 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	57,595,211 - 57,611,107 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	57,687,928 - 57,703,824 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	57,687,928 - 57,703,824 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	57,535,735 - 57,551,629 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	57,486,065 - 57,501,958 (+)	NCBI		MGSCv36	mm8
Celera	9	85,889,319 - 85,895,530 (-)	NCBI		Celera
Cytogenetic Map	9	B	NCBI
cM Map	9	31.34	NCBI

Cyp1a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	66,991,940 - 66,998,014 (+)	NCBI		GRCr8
mRatBN7.2	8	58,096,021 - 58,102,130 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	58,096,077 - 58,102,125 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	63,629,083 - 63,635,108 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	61,906,655 - 61,912,680 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	59,771,206 - 59,777,229 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	62,472,087 - 62,478,122 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	62,472,095 - 62,478,147 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	62,249,046 - 62,255,081 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	61,462,207 - 61,468,237 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	61,481,260 - 61,487,291 (+)	NCBI
Celera	8	57,561,801 - 57,567,827 (+)	NCBI		Celera
RH 3.4 Map	8	671.2	RGD
Cytogenetic Map	8	q24	NCBI

CYP1A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	63,949,165 - 63,957,527 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	68,112,819 - 68,121,152 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	53,664,968 - 53,672,277 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	73,284,566 - 73,290,636 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	73,284,566 - 73,290,636 (-)	Ensembl	panpan1.1		panPan2

CYP1A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	37,793,277 - 37,799,535 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	37,793,508 - 37,796,866 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	37,726,194 - 37,732,463 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	37,998,587 - 38,004,872 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	37,998,848 - 38,002,205 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	37,951,106 - 37,957,375 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	37,976,995 - 37,983,257 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	38,232,580 - 38,238,845 (-)	NCBI		UU_Cfam_GSD_1.0

LOC101969148
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	115,834,681 - 115,840,894 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	33,682,730 - 33,688,332 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	33,682,730 - 33,688,332 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CYP1A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	58,802,887 - 58,809,775 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	58,802,887 - 58,809,155 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	63,491,496 - 63,497,751 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	7	q	NCBI

CYP1A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	8,753,236 - 8,759,378 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	8,753,327 - 8,759,384 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	132,870,282 - 132,876,394 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LOC101707509
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004627988	7 - 1,323 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005393546	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005393547	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01042426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDK01432211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000009989 ⟹ ENSCLAP00000009860

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955450	3,183,750 - 3,189,488 (+)	Ensembl

Ensembl Acc Id:

ENSCLAT00000009990 ⟹ ENSCLAP00000009861

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955450	3,185,486 - 3,188,800 (+)	Ensembl

RefSeq Acc Id:

XM_005393546 ⟹ XP_005393603

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955450	3,183,958 - 3,189,488 (+)	NCBI

Sequence:

show sequence

AGAATCTGGAGCCTCCCCATCCTCCTCAGGGTCCTGGCCCCAGAGACTGCTCTTCTCAGCTTAG
CACCTCACAGCCAAGGCAGCTGCCTGGAAGATCCTGCCACTACTCATGTTTTCTGTGTCTGAGC
TTCCAATGTTCACCTCCGCTGTGGACCTACTCCTGGCTGCCACCATCTTCTGCTTAGTACTCTG
GGTGGTCAGAGCCTCTAGGCCTCAGGTCCCCAAAGGCCTGAAGAGCCCCCCAGGGCCCTGGGGG
TGGCCACTGATCGGGCATGTGCTGACCCTGGGCAAGAATCCACACCTGGCGCTGGCCAGGCTGA
GTGCTCGCTATGGGGATGTGCTGCAGATCCGCATCGGCTCCACGCCTGTGGTGGTGCTGAGTGG
TCTAGACACCATCCGCCAGGCCTTGGTGCGGCAGGGCGACGACTTCAAGGGCCGGCCTGACTTC
TACAGCTTCACCTTCATCTCTGATGGCCAAAGCATGACTTTCAACCCAGATTCAGGCCCCGTGT
GGGCTGCCCGCCGGCGCCTCGCGCAGGATGCCCTGAAGAGTTTCTCTTTGGCCTCAGACCCGGC
TTCTGCGTCCTCCTGCTACTTAGAGGAGCATGTGAAGAAGGAGGCTGAGTACCTTATCAACAAG
TTCCAGGAGCTCATGGCAGGGCCTGGACACTTTGACCCCTACAGATATGTGGTGGTCTCAGTGG
CCAATGTCATCTCTGCCATATGCTTTGGGCGGCGCTATGACCACGACCACCAAGAGCTGCTTGA
TTTAGTCGACCTGAATAATGAGTTTGGGGAGCTGACTGCCTCAGGAAACCCAGTTGACTTCATC
CCCATCCTCCAGTATCTGCCCAGCTCTTCCATGGATACCTTCAAGGACCTGAACAGGAAGTTCT
CTGTCTTCATAAACAAGATGGTCAAGGAGCACTACAAAACATTTGAGAAGGGTCACATCCGGGA
CATCACAGACAGCCTGATAGAGCACTGTCAGGACAGGAAGCTGGATGAGAACGCCAATATTCTG
CTTTCAGACCAGAAGATCATTAGCATTGTCTTGGACCTCTTTGGAGCTGGTTTTGACACAGTCA
CAACTGCCATCTCCTGGAGCCTCCTGTACCTCGTGACGAACCCAAGGATACAGAGAAAGATCCA
GGAGGAGCTGGATACTGTGATTGGTAGGGAGCGGTGGCCCCAGCTCACTGACCGAACCCAGCTG
CCCTACATGGAAGCCTTCATCCTGGAGGTCTTCCGGCACTCCTCCTTCTTGCCCTTCACCATTC
CACACAGCACCACAAGAGACACAAGTTTGAATGGATTTTACATCCCAAAGGGGTGCTGTATTTT
TGTGAACCAGTGGCAGATTAACCATGACCTGAAGCTGTGGGGGGACCCATCTGTGTTCCGGCCT
GAACGCTTTCTTTCTCCGGATGGCACTGTGGACAAGGCACTGAGTGAGAAGGTGATTATCTTTG
GCTTGGGCAAGCGCCGATGCATCGGGGAGATCATTGGTCGCTGGGAGGTCTTCCTTTTCCTGGC
CATCCTGCTGCAGCAACTGGAATTCAGTGTATCACCAGGAGTGAAAGTAGACATGACCCCCATC
TATGGTCTGTCTATGAAGCATCCCCGATGCAAGCACTTCCAGGCACAGCTACGTCCTTCTGTCC
TCAAGTGTCCTGAAGCCTAGATCTGTCTACCTGGTCTGCATGGGGAGTAGATCTGGGCTTCAGC
CTGAAACTCATAGACTCTTGGAGAATCATACCAGCTCTCTACCCCAACTTCCCACGCTGCATAC
TAAACACAGACAGTGGGGACAGCAGAAGGATGTAGGAACCCATGGGGTTTCCACAGAGGTGCCT
GAGCTGGGAGCCCAGCAGAGTTGGGTCTTTCAGCCTCTGGGAACCTCTGAGGAGCTCTCTGGAA
GTCTCTGGGCCTACCAGCTGCCAGGCTGGAGAAACATTTAGAGCAGGCCTGCCAGGACCTGTCT
GATCCTTGTGGGATCCTCCTGGAGGAAGGGAAGAACCAGCCCAAGAGACTGGCACAGAGGTGGA
ATTGCCATTTTCCCAAGGCTAGGTGATGTGCTTCCATGGGCTGGCAACTCCATGCCTGGGGAAT
CACATTTGTCTGCCCTACCTCCAGACAGTAACAAACAGGGCTGCCTCCTATCCTTGTAAAACCC
TTGTTCCTGTCCAGGGTGGGGATGGGACTTGCATCTAAGAAGAATTACACCTAAGACCAAGGAC
CAGGGCTGGCATGAAGGAATATTTCAGTTACCTTTTCCTGGCATCCCTTATCTACACCCCATGT
GAATTTTTTTTGTATGTGATACTAGGGATTAAACTCAGGCCCTTTACCCAGAGCTACATCCCTA
ACCT

hide sequence

RefSeq Acc Id:

XM_005393547 ⟹ XP_005393604

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955450	3,183,958 - 3,189,488 (+)	NCBI

Sequence:

show sequence

AGAATCTGGAGCCTCCCCATCCTCCTCAGGGTCCTGGCCCCAGAGACTGCTCTTCTCAGCTTAG
CACCTCACAGCCAAGGCTGCCTGGAAGATCCTGCCACTACTCATGTTTTCTGTGTCTGAGCTTC
CAATGTTCACCTCCGCTGTGGACCTACTCCTGGCTGCCACCATCTTCTGCTTAGTACTCTGGGT
GGTCAGAGCCTCTAGGCCTCAGGTCCCCAAAGGCCTGAAGAGCCCCCCAGGGCCCTGGGGGTGG
CCACTGATCGGGCATGTGCTGACCCTGGGCAAGAATCCACACCTGGCGCTGGCCAGGCTGAGTG
CTCGCTATGGGGATGTGCTGCAGATCCGCATCGGCTCCACGCCTGTGGTGGTGCTGAGTGGTCT
AGACACCATCCGCCAGGCCTTGGTGCGGCAGGGCGACGACTTCAAGGGCCGGCCTGACTTCTAC
AGCTTCACCTTCATCTCTGATGGCCAAAGCATGACTTTCAACCCAGATTCAGGCCCCGTGTGGG
CTGCCCGCCGGCGCCTCGCGCAGGATGCCCTGAAGAGTTTCTCTTTGGCCTCAGACCCGGCTTC
TGCGTCCTCCTGCTACTTAGAGGAGCATGTGAAGAAGGAGGCTGAGTACCTTATCAACAAGTTC
CAGGAGCTCATGGCAGGGCCTGGACACTTTGACCCCTACAGATATGTGGTGGTCTCAGTGGCCA
ATGTCATCTCTGCCATATGCTTTGGGCGGCGCTATGACCACGACCACCAAGAGCTGCTTGATTT
AGTCGACCTGAATAATGAGTTTGGGGAGCTGACTGCCTCAGGAAACCCAGTTGACTTCATCCCC
ATCCTCCAGTATCTGCCCAGCTCTTCCATGGATACCTTCAAGGACCTGAACAGGAAGTTCTCTG
TCTTCATAAACAAGATGGTCAAGGAGCACTACAAAACATTTGAGAAGGGTCACATCCGGGACAT
CACAGACAGCCTGATAGAGCACTGTCAGGACAGGAAGCTGGATGAGAACGCCAATATTCTGCTT
TCAGACCAGAAGATCATTAGCATTGTCTTGGACCTCTTTGGAGCTGGTTTTGACACAGTCACAA
CTGCCATCTCCTGGAGCCTCCTGTACCTCGTGACGAACCCAAGGATACAGAGAAAGATCCAGGA
GGAGCTGGATACTGTGATTGGTAGGGAGCGGTGGCCCCAGCTCACTGACCGAACCCAGCTGCCC
TACATGGAAGCCTTCATCCTGGAGGTCTTCCGGCACTCCTCCTTCTTGCCCTTCACCATTCCAC
ACAGCACCACAAGAGACACAAGTTTGAATGGATTTTACATCCCAAAGGGGTGCTGTATTTTTGT
GAACCAGTGGCAGATTAACCATGACCTGAAGCTGTGGGGGGACCCATCTGTGTTCCGGCCTGAA
CGCTTTCTTTCTCCGGATGGCACTGTGGACAAGGCACTGAGTGAGAAGGTGATTATCTTTGGCT
TGGGCAAGCGCCGATGCATCGGGGAGATCATTGGTCGCTGGGAGGTCTTCCTTTTCCTGGCCAT
CCTGCTGCAGCAACTGGAATTCAGTGTATCACCAGGAGTGAAAGTAGACATGACCCCCATCTAT
GGTCTGTCTATGAAGCATCCCCGATGCAAGCACTTCCAGGCACAGCTACGTCCTTCTGTCCTCA
AGTGTCCTGAAGCCTAGATCTGTCTACCTGGTCTGCATGGGGAGTAGATCTGGGCTTCAGCCTG
AAACTCATAGACTCTTGGAGAATCATACCAGCTCTCTACCCCAACTTCCCACGCTGCATACTAA
ACACAGACAGTGGGGACAGCAGAAGGATGTAGGAACCCATGGGGTTTCCACAGAGGTGCCTGAG
CTGGGAGCCCAGCAGAGTTGGGTCTTTCAGCCTCTGGGAACCTCTGAGGAGCTCTCTGGAAGTC
TCTGGGCCTACCAGCTGCCAGGCTGGAGAAACATTTAGAGCAGGCCTGCCAGGACCTGTCTGAT
CCTTGTGGGATCCTCCTGGAGGAAGGGAAGAACCAGCCCAAGAGACTGGCACAGAGGTGGAATT
GCCATTTTCCCAAGGCTAGGTGATGTGCTTCCATGGGCTGGCAACTCCATGCCTGGGGAATCAC
ATTTGTCTGCCCTACCTCCAGACAGTAACAAACAGGGCTGCCTCCTATCCTTGTAAAACCCTTG
TTCCTGTCCAGGGTGGGGATGGGACTTGCATCTAAGAAGAATTACACCTAAGACCAAGGACCAG
GGCTGGCATGAAGGAATATTTCAGTTACCTTTTCCTGGCATCCCTTATCTACACCCCATGTGAA
TTTTTTTTGTATGTGATACTAGGGATTAAACTCAGGCCCTTTACCCAGAGCTACATCCCTAACC
T

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Protein Sequences


Protein RefSeqs	XP_005393603	(Get FASTA)	NCBI Sequence Viewer
	XP_005393604	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000009860
	ENSCLAP00000009860.1
	ENSCLAP00000009861
	ENSCLAP00000009861.1

RefSeq Acc Id:

XP_005393603 ⟸ XM_005393546

- UniProtKB:

A0A8C2V8W5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFSVSELPMFTSAVDLLLAATIFCLVLWVVRASRPQVPKGLKSPPGPWGWPLIGHVLTLGKNPH
LALARLSARYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDFYSFTFISDGQSMTFN
PDSGPVWAARRRLAQDALKSFSLASDPASASSCYLEEHVKKEAEYLINKFQELMAGPGHFDPYR
YVVVSVANVISAICFGRRYDHDHQELLDLVDLNNEFGELTASGNPVDFIPILQYLPSSSMDTFK
DLNRKFSVFINKMVKEHYKTFEKGHIRDITDSLIEHCQDRKLDENANILLSDQKIISIVLDLFG
AGFDTVTTAISWSLLYLVTNPRIQRKIQEELDTVIGRERWPQLTDRTQLPYMEAFILEVFRHSS
FLPFTIPHSTTRDTSLNGFYIPKGCCIFVNQWQINHDLKLWGDPSVFRPERFLSPDGTVDKALS
EKVIIFGLGKRRCIGEIIGRWEVFLFLAILLQQLEFSVSPGVKVDMTPIYGLSMKHPRCKHFQA
QLRPSVLKCPEA

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RefSeq Acc Id:

XP_005393604 ⟸ XM_005393547

- UniProtKB:

A0A8C2V8W5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFSVSELPMFTSAVDLLLAATIFCLVLWVVRASRPQVPKGLKSPPGPWGWPLIGHVLTLGKNPH
LALARLSARYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDFYSFTFISDGQSMTFN
PDSGPVWAARRRLAQDALKSFSLASDPASASSCYLEEHVKKEAEYLINKFQELMAGPGHFDPYR
YVVVSVANVISAICFGRRYDHDHQELLDLVDLNNEFGELTASGNPVDFIPILQYLPSSSMDTFK
DLNRKFSVFINKMVKEHYKTFEKGHIRDITDSLIEHCQDRKLDENANILLSDQKIISIVLDLFG
AGFDTVTTAISWSLLYLVTNPRIQRKIQEELDTVIGRERWPQLTDRTQLPYMEAFILEVFRHSS
FLPFTIPHSTTRDTSLNGFYIPKGCCIFVNQWQINHDLKLWGDPSVFRPERFLSPDGTVDKALS
EKVIIFGLGKRRCIGEIIGRWEVFLFLAILLQQLEFSVSPGVKVDMTPIYGLSMKHPRCKHFQA
QLRPSVLKCPEA

hide sequence

Ensembl Acc Id:

ENSCLAP00000009861 ⟸ ENSCLAT00000009990

Ensembl Acc Id:

ENSCLAP00000009860 ⟸ ENSCLAT00000009989

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000006828	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000009989	ENTREZGENE
	ENSCLAT00000009989.1	UniProtKB/TrEMBL
	ENSCLAT00000009990	ENTREZGENE
	ENSCLAT00000009990.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.630.10	UniProtKB/TrEMBL
InterPro	Cyt_P450	UniProtKB/TrEMBL
	Cyt_P450_CS	UniProtKB/TrEMBL
	Cyt_P450_E_grp-I	UniProtKB/TrEMBL
	Cyt_P450_E_grp-I_CYP1	UniProtKB/TrEMBL
	Cyt_P450_sf	UniProtKB/TrEMBL
NCBI Gene	LOC102010850	ENTREZGENE
PANTHER	CYTOCHROME P450 1A2	UniProtKB/TrEMBL
	STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE	UniProtKB/TrEMBL
Pfam	p450	UniProtKB/TrEMBL
PRINTS	EP450I	UniProtKB/TrEMBL
	EP450ICYP1A	UniProtKB/TrEMBL
	P450	UniProtKB/TrEMBL
PROSITE	CYTOCHROME_P450	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48264	UniProtKB/TrEMBL
UniProt	A0A8C2V3S6_CHILA	UniProtKB/TrEMBL
	A0A8C2V8W5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-25	LOC102010850	cytochrome P450 1A1		cytochrome P450 1A1-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB