Fis1 (fission, mitochondrial 1) - Rat Genome Database

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Gene: Fis1 (fission, mitochondrial 1) Chinchilla lanigera
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Symbol: Fis1
Name: fission, mitochondrial 1
RGD ID: 9055335
Description: ENCODES a protein that exhibits identical protein binding (ortholog); lipid binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); cellular response to lipid (ortholog); cellular response to peptide (ortholog); PARTICIPATES IN mitochondria fission pathway; ASSOCIATED WITH acute kidney failure (ortholog); Alzheimer's disease (ortholog); chronic kidney disease (ortholog); FOUND IN mitochondrial outer membrane (ortholog); mitochondrion (ortholog); peroxisomal membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fission 1 (mitochondrial outer membrane) homolog
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545616,038,221 - 16,060,623 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545616,057,158 - 16,060,623 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fis1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545616,038,221 - 16,060,623 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545616,057,158 - 16,060,623 (+)NCBIChiLan1.0ChiLan1.0
FIS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387101,239,472 - 101,245,081 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7101,239,458 - 101,252,316 (-)EnsemblGRCh38hg38GRCh38
GRCh377100,882,753 - 100,888,362 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,669,613 - 100,675,091 (-)NCBINCBI36Build 36hg18NCBI36
Build 347100,476,327 - 100,481,801NCBI
Celera795,892,051 - 95,897,529 (-)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef795,475,936 - 95,481,415 (-)NCBIHuRef
CHM1_17100,813,303 - 100,818,781 (-)NCBICHM1_1
T2T-CHM13v2.07102,562,935 - 102,568,544 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27100,241,280 - 100,246,758 (-)NCBI
Fis1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395136,982,129 - 136,995,088 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5136,982,129 - 136,995,088 (+)EnsemblGRCm39 Ensembl
GRCm385136,953,275 - 136,966,234 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5136,953,275 - 136,966,234 (+)EnsemblGRCm38mm10GRCm38
MGSCv375137,429,145 - 137,442,104 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365137,246,713 - 137,250,859 (+)NCBIMGSCv36mm8
Celera5133,969,492 - 133,982,284 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.06NCBI
Fis1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81225,345,239 - 25,360,135 (-)NCBIGRCr8
mRatBN7.21219,708,560 - 19,723,392 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1219,708,558 - 19,723,377 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1220,847,143 - 20,862,230 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,459,848 - 21,474,937 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01220,524,895 - 20,540,015 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01222,750,485 - 22,765,324 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,750,485 - 22,765,308 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,760,051 - 24,774,751 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41220,806,840 - 20,821,766 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11220,807,273 - 20,811,373 (+)NCBI
Celera1221,483,983 - 21,498,749 (-)NCBICelera
Cytogenetic Map12q12NCBI
FIS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26119,252,931 - 119,260,623 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17167,517,560 - 167,523,003 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0793,381,058 - 93,386,483 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17106,621,211 - 106,626,612 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7106,621,211 - 106,626,683 (-)Ensemblpanpan1.1panPan2
FIS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.168,642,014 - 8,645,812 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl68,642,039 - 8,648,851 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha610,339,369 - 10,343,166 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.068,461,512 - 8,465,308 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl68,458,742 - 8,465,308 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.168,417,290 - 8,421,077 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.068,392,322 - 8,396,123 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.068,557,014 - 8,560,797 (+)NCBIUU_Cfam_GSD_1.0
Fis1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344132,919,990 - 132,923,784 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365431,112,742 - 1,116,518 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365431,112,746 - 1,116,521 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FIS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,937,453 - 8,946,955 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,938,250 - 8,942,102 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FIS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12811,934,848 - 11,940,230 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2811,934,821 - 11,941,901 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660704,412,698 - 4,418,083 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fis1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,052,820 - 16,057,098 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,052,777 - 16,056,438 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Ensembl Acc Id: ENSCLAT00000018323   ⟹   ENSCLAP00000018144
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545616,038,221 - 16,060,427 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000018324   ⟹   ENSCLAP00000018145
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545616,057,158 - 16,060,623 (+)Ensembl
RefSeq Acc Id: XM_005396858   ⟹   XP_005396915
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545616,057,158 - 16,060,623 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005396915 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000018144.1
  ENSCLAP00000018145
  ENSCLAP00000018145.1
RefSeq Acc Id: XP_005396915   ⟸   XM_005396858
- UniProtKB: A0A8C2VN53 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000018144   ⟸   ENSCLAT00000018323
Ensembl Acc Id: ENSCLAP00000018145   ⟸   ENSCLAT00000018324


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012445 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018323.1 UniProtKB/TrEMBL
  ENSCLAT00000018324 ENTREZGENE
  ENSCLAT00000018324.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro Fis1 UniProtKB/TrEMBL
  Fis1_cytosol UniProtKB/TrEMBL
  Fis1_TPR_C UniProtKB/TrEMBL
  Fis1_TPR_N UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
NCBI Gene Fis1 ENTREZGENE
PANTHER MITOCHONDRIAL FISSION 1 PROTEIN UniProtKB/TrEMBL
  PTHR13247 UniProtKB/TrEMBL
Pfam Fis1_TPR_C UniProtKB/TrEMBL
  Fis1_TPR_N UniProtKB/TrEMBL
PIRSF TPR_repeat_11_Fis1 UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A8C2VN53 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VTJ4_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Fis1  fission, mitochondrial 1    fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED