Slc1a7 (solute carrier family 1 member 7)

Gene: Slc1a7 (solute carrier family 1 member 7) Chinchilla lanigera

Analyze

Symbol:

Slc1a7

Name:

solute carrier family 1 member 7

RGD ID:

9055052

Description:

ENCODES a protein that exhibits extracellularly glutamate-gated chloride channel activity (ortholog); glutamate:sodium symporter activity (ortholog); L-glutamate transmembrane transporter activity (ortholog); INVOLVED IN chloride transmembrane transport (ortholog); L-glutamate transmembrane transport (ortholog); monoatomic anion transmembrane transport (ortholog); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); FOUND IN axon terminus (ortholog); glutamatergic synapse (ortholog); photoreceptor cell terminal bouton (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

excitatory amino acid transporter 5; solute carrier family 1 (glutamate transporter), member 7

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955464	6,032,629 - 6,069,483 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955464	6,032,629 - 6,069,483 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chloride transmembrane transport (ISO)

L-glutamate transmembrane transport (ISO)

monoatomic anion transmembrane transport (ISO)

neurotransmitter uptake (ISO)

Cellular Component

axon terminus (ISO)

glutamatergic synapse (ISO)

photoreceptor cell terminal bouton (ISO)

plasma membrane (ISO)

postsynaptic membrane (ISO)

presynaptic membrane (ISO)

Molecular Function

extracellularly glutamate-gated chloride channel activity (ISO)

glutamate:sodium symporter activity (ISO)

L-glutamate transmembrane transporter activity (ISO)

monoatomic anion transmembrane transporter activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Slc1a7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955464	6,032,629 - 6,069,483 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955464	6,032,629 - 6,069,483 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC1A7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	53,087,183 - 53,142,638 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	53,087,179 - 53,142,638 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	53,552,855 - 53,608,310 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	53,325,443 - 53,380,837 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	53,264,876 - 53,320,270	NCBI
Celera	1	51,840,827 - 51,896,289 (-)	NCBI		Celera
Cytogenetic Map	1	p32.3	NCBI
HuRef	1	51,668,335 - 51,723,701 (-)	NCBI		HuRef
CHM1_1	1	53,670,009 - 53,725,460 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	52,968,685 - 53,024,057 (-)	NCBI		T2T-CHM13v2.0

Slc1a7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	107,825,603 - 107,870,726 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	107,825,529 - 107,870,729 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	107,968,406 - 108,013,529 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	107,968,332 - 108,013,532 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	107,640,939 - 107,686,137 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	107,466,264 - 107,511,461 (+)	NCBI		MGSCv36	mm8
Celera	4	106,317,626 - 106,362,935 (+)	NCBI		Celera
Cytogenetic Map	4	C7	NCBI
cM Map	4	50.18	NCBI

Slc1a7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	127,959,769 - 128,003,899 (+)	NCBI		GRCr8
mRatBN7.2	5	122,731,003 - 122,775,139 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	122,731,003 - 122,775,134 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	125,351,046 - 125,395,385 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	127,074,095 - 127,118,431 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	127,125,404 - 127,169,736 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	127,571,114 - 127,616,033 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	127,571,114 - 127,616,033 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	131,418,724 - 131,463,643 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	129,075,111 - 129,118,812 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	129,080,557 - 129,123,207 (+)	NCBI
Celera	5	121,472,346 - 121,518,187 (+)	NCBI		Celera
Cytogenetic Map	5	q34	NCBI

SLC1A7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	173,695,272 - 173,752,067 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	172,836,043 - 172,893,244 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	52,359,809 - 52,415,466 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	53,960,400 - 54,015,396 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	53,960,400 - 54,015,396 (-)	Ensembl	panpan1.1		panPan2

SLC1A7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	55,782,291 - 55,825,504 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	55,782,291 - 55,825,336 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	55,848,486 - 55,891,182 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	55,971,868 - 56,014,737 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	55,971,868 - 56,014,569 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	55,963,986 - 56,006,683 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	55,855,490 - 55,898,142 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	56,244,733 - 56,287,361 (+)	NCBI		UU_Cfam_GSD_1.0

Slc1a7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	67,443,673 - 67,487,295 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936522	7,928,742 - 7,973,399 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936522	7,928,847 - 7,972,618 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC1A7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	159,106,061 - 159,153,761 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	159,106,083 - 159,153,766 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	146,824,786 - 146,866,509 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC1A7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	79,779,277 - 79,832,786 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	79,779,759 - 79,831,960 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	37,448,191 - 37,501,993 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc1a7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624859	40,272 - 75,242 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624859	34,530 - 75,246 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005398562	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01050017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBBH01023325	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000015410 ⟹ ENSCLAP00000015250

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955464	6,032,629 - 6,069,483 (+)	Ensembl

RefSeq Acc Id:

XM_005398562 ⟹ XP_005398619

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955464	6,032,629 - 6,069,483 (+)	NCBI

Sequence:

show sequence

ATGGAATGGTGCCGTGCCCCATGCCAGCAGGCCCGGCTCACCATGGTGCTGGGTGCCCTTCTGG
TGCGAGGCAGGGACGTGTGCCGGCGGAACGGACTGCTCATCCTATCGGTGCTCTCTGTCATCGT
GGGCTGCCTCCTCGGCTTCTTCCTGAGGACCCGGCGCCTCTCACCACAGGAGATTAGTTACTTC
CAGTTCCCCGGAGAGCTCTTGATGAGGATGCTGAAGATGCTGATCCTGCCACTGGTGGTCTCCA
GCCTGATGTCCGGTCTCGCCTCCCTGGATGCCAAGACCTCCAGCCGCCTGGGCATCCTCACTGT
GGCTTACTACTTGTGGACCACTTTCCTGGCCGTCGTTGTGGGCATCGTCATGGTCTCCATCATC
CACCCGGGGGGCGCAGCCCAGAAGGAGACGACAGAGCAGAGCGGGAAGCCGGTCATGAGCTCAG
CCGACGCCCTTCTGGACCTCATCCGGAACATGTTCCCAGCCAACCTGGTGGAAGCCACATTCAA
ACAGTACCGCACCAAGACCACCCCGGTTATCAAGTCCCCCAAGGTGACCCCAGAGGAGGCCCCG
CCGCGACGGATCCTCATCTACGGGGTCCAGGAAGAGAATGGCTCTCGTGTGCAGAACTTCGCCT
TGGACCTGACCCCACCACCTGAGATCGTCTACAGGTCGGAGCCCGGCACCAGTGATGGCATGAA
CGTGCTGGGCATTGTCATATTCTCTGCCACCATGGGAATCATGCTAGGCCGCATGGGTGACAGC
GGGGCCCCCCTGGTCAGCTTCTGCCAGTGCCTCAACGAGTCTGTCATGAAGATCGTGGCAGTGG
CTGTGTGGTACTTCCCCTTTGGCATTGTGTTTCTCATCGCCGGCAAGATCCTGGAGATGGATGA
CCCCAAGGCGGTCGGAAAGAAGCTGGGCTTCTACGCCATCACCGTGGTGTGTGGCCTTGTGGTC
CACGGCCTCTTCATCCTGCCCCTGCTCTACTTCTTCATCACCAAGAAGAACCCCATTGTCTTCA
TCCGCGGTGTCCTCCAGGCCCTGCTCATCGCACTGGCCACCTCCTCCAGCTCAGCCACACTGCC
CATCACCTTCAAGTGCCTGCTGGAAAACAACCACATTGACCGGCGCATTGCCCGCTTTGTGCTG
CCCGTGGGTGCCACCATCAACATGGATGGCACTGCGCTCTATGAGGCTGTGGCCGCCATCTTCA
TTGCCCAGGTCAACAACTACGAGCTGGACTTTGGCCAGATCATCACCATCAGCATCACAGCCAC
CGCGGCCAGCATTGGGGCAGCTGGCATCCCCCAGGCCGGGCTTGTCACCATGGTCATTGTGCTC
ACCTCTGTGGGACTGCCCACTGACGACATCAACCTCATCATCGCTGTGGACTGGGCTCTGGACC
GTTTCCGCACCATGATTAACGTGCTGGGTGATGCATTGGCTGCAGGGATCATGGCCCACATCTG
TCGCAAGGACTTTGCACGGGACACTGGCACTGAGAAGCTGCCACCCTGTGAGACCAAGCCGGTG
AGCCTTCAGGAGATCGTGGCGACCCAGCAGAATGGCTGTGTGAAGAGCGTGGCTGAGGCCTCAG
AGCTGACCCTCGGCCCCACCTGCCCCCACCACATCCCTGTGCAGGTGGAGCAGGATGAGGAGCT
GGCCACGGCCAGCCTGGACCACTGCACCATAGAGATCAGCGAGCTGGAGACCAACGTGTGAGCC
TGTGGGGCAGGAGCAGAACTCGCGGCTCACCTGAGCAGCCAGGCAGCCGGCAGGCACCAGGTTC
ATGCATTCTGCTCTCCTTGAGAGGCTGGAATTAGCCTGAGAGGTGGGAAATAGAATTTCAGAGG
GAGAGGGTGCACGCTGGAGCCTCATCCTGAGCGCGGTGGCCTGCCCAGCCCAAACCTTAACTGT
GCTACCTTGAAAGCCTATGTGGGGGTGAGGCAGGGGTTGTCATCCCCATTTTCTGGGTCACAGA
TTTGAGGTTCTGAGCACTTGCCCATGGTCTTGAGAAAGCAATGTCAGGGCTAGGATACTAACTC
AAGTCTCTGAGCCCTGGCTACTCCTTCCTGTAGGACAGAGTGGCCTGTAGGGACAGACGTGGAG
GGGTGCCACAGTCACTACTGCTTCTAATTCATGAGGATGTAATAACAACATCCTGGTTTCCACC
CCAGCCATGTCCAGGCCCAGGCCAGCCCTCACCCCACCCCATAGAACAGACAAATAGCTGCCCC
CAAACCTGGGCCTGTCCTGGGCTGAGACCCGCTTGCTGCCTTCCACGTGCCATGGCCTGCCCTG
TCCCTGCCCACCAGCTGAGTCTCCCACAGCTTGTCTGATGTGGACCGGATATCTTTACTAGGAC
CCTGGAAAGGCCTGGTGGGGACATCCAGGCCAGCTTGCTGTGGGCAGGAGGGCAGGCCCTGGTG
GCACCCTGGGGTCAGAACTCCCCCAAGGCCCATGTGACAAAGTGGAGTCACAATTCCTATCCCT
TCCTGTGTTAGCAAATTCAGTGATA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005398619	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000015250
	ENSCLAP00000015250.1

RefSeq Acc Id:

XP_005398619 ⟸ XM_005398562

- UniProtKB:

A0A8C2VGH0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEWCRAPCQQARLTMVLGALLVRGRDVCRRNGLLILSVLSVIVGCLLGFFLRTRRLSPQEISYF
QFPGELLMRMLKMLILPLVVSSLMSGLASLDAKTSSRLGILTVAYYLWTTFLAVVVGIVMVSII
HPGGAAQKETTEQSGKPVMSSADALLDLIRNMFPANLVEATFKQYRTKTTPVIKSPKVTPEEAP
PRRILIYGVQEENGSRVQNFALDLTPPPEIVYRSEPGTSDGMNVLGIVIFSATMGIMLGRMGDS
GAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPKAVGKKLGFYAITVVCGLVV
HGLFILPLLYFFITKKNPIVFIRGVLQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVL
PVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVL
TSVGLPTDDINLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKDFARDTGTEKLPPCETKPV
SLQEIVATQQNGCVKSVAEASELTLGPTCPHHIPVQVEQDEELATASLDHCTIEISELETNV

hide sequence

RefSeq Acc Id:

ENSCLAP00000015250 ⟸ ENSCLAT00000015410

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000010500	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000015410	ENTREZGENE
	ENSCLAT00000015410.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.3860.10	UniProtKB/TrEMBL
InterPro	Na-dicarboxylate_symporter	UniProtKB/TrEMBL
	Na-dicarboxylate_symporter_CS	UniProtKB/TrEMBL
	Na:dicarbo_symporter_sf	UniProtKB/TrEMBL
NCBI Gene	Slc1a7	ENTREZGENE
PANTHER	EXCITATORY AMINO ACID TRANSPORTER 5	UniProtKB/TrEMBL
	SODIUM/DICARBOXYLATE SYMPORTER-RELATED	UniProtKB/TrEMBL
Pfam	SDF	UniProtKB/TrEMBL
PRINTS	EDTRNSPORT	UniProtKB/TrEMBL
PROSITE	NA_DICARBOXYL_SYMP_1	UniProtKB/TrEMBL
	NA_DICARBOXYL_SYMP_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF118215	UniProtKB/TrEMBL
UniProt	A0A8C2VGH0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Slc1a7	solute carrier family 1 member 7		solute carrier family 1 (glutamate transporter), member 7	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar